Airway irritation among indoor swimming pool personnel: Trichloramine exposure, exhaled NO and protein profiling of nasal lavage fluids

International Archives of Occupational and Environmental Health

Volumn 86, Issue 5, 2013, Pages 571-580

  Fornander, Louise ^a   Ghafouri, Bijar ^a,b   Lindahl, Mats ^a   Graff, Pål ^a,b  

^a LINKÖPING UNIVERSITY   (Sweden)

^b Department of Clinical Immunology and Transfusion Medicine   (Sweden)

Author keywords

Innate immunity; Occupational medicine; Proteomics; Upper respiratory tract

Indexed keywords

BIOLOGICAL MARKER; CHLORIDE; NITRIC OXIDE; NITROGEN CHLORIDE; NITROGEN DERIVATIVE; PROTEOME;

ADULT; AIR POLLUTANT; ARTICLE; CHEMISTRY; CROSS-SECTIONAL STUDY; FEMALE; HUMAN; IMMUNOBLOTTING; MALE; MASS SPECTROMETRY; METABOLISM; MIDDLE AGED; NOSE MUCUS; OCCUPATIONAL DISEASE; OCCUPATIONAL EXPOSURE; PREVALENCE; RESPIRATORY TRACT DISEASE; RISK FACTOR; SWEDEN; SWIMMING POOL; TWO DIMENSIONAL GEL ELECTROPHORESIS;

ADULT; AIR POLLUTANTS, OCCUPATIONAL; BIOLOGICAL MARKERS; CHLORIDES; CROSS-SECTIONAL STUDIES; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; FEMALE; HUMANS; IMMUNOBLOTTING; MALE; MIDDLE AGED; NASAL LAVAGE FLUID; NITRIC OXIDE; NITROGEN COMPOUNDS; OCCUPATIONAL DISEASES; OCCUPATIONAL EXPOSURE; PREVALENCE; PROTEOME; RESPIRATORY TRACT DISEASES; RISK FACTORS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; SWEDEN; SWIMMING POOLS;

EID: 84879098039     PISSN: 03400131     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00420-012-0790-4     Document Type: Article

References (40)

1. Archimandriti DT, Dalavanga YA, Cianti R, Bianchi L, Manda-Stachouli C, Armini A, Koukkou AI, Rottoli P, Constantopoulos SH, Bini L (2009) Proteome analysis of bronchoalveolar lavage in individuals from metsovo, nonoccupationally exposed to asbestos. J Proteome Res 8(2):860-869. doi: 10.1021/pr800370n
2. Bernard A, Carbonnelle S, Nickmilder M, de Burbure C (2005) Non-invasive biomarkers of pulmonary damage and inflammation: application to children exposed to ozone and trichloramine. Toxicol Appl Pharmacol 206(2):185-190. doi: 10.1016/j.taap.2004.10.022
3. Bernard A, Carbonnelle S, de Burbure C, Michel O, Nickmilder M (2006) Chlorinated pool attendance, atopy, and the risk of asthma during childhood. Environ Health Perspect 114(10):1567-1573
4. Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254
5. Carbonnelle S, Francaux M, Doyle I, Dumont X, de Burbure C, Morel G, Michel O, Bernard A (2002) Changes in serum pneumoproteins caused by short-term exposures to nitrogen trichloride in indoor chlorinated swimming pools. Biomarkers 7(6):464-478. doi: 10.1080/13547500210166612
6. Dang B, Chen L, Mueller C, Dunn KH, Almaguer D, Roberts JL, Otto CS (2010) Ocular and respiratory symptoms among lifeguards at a hotel indoor waterpark resort. J Occup Environ Med 52(2):207-213. doi: 10.1097/JOM. 0b013e3181cf00d5
7. Demange V, Bohadana A, Massin N, Wild P (2009) Exhaled nitric oxide and airway hyperresponsiveness in workers: a preliminary study in lifeguards. BMC Pulm Med 9:53. doi: 10.1186/1471-2466-9-53
8. Ernst P, Dales RE, Nunes F, Becklake MR (1989) Relation of airway responsiveness to duration of work in a dusty environment. Thorax 44(2):116-120
9. Fantuzzi G, Righi E, Predieri G, Giacobazzi P, Mastroianni K, Aggazzotti G (2010) Prevalence of ocular, respiratory and cutaneous symptoms in indoor swimming pool workers and exposure to disinfection by-products (dbps). Int J Environ Res Public Health 7(4):1379-1391. doi: 10.3390/ijerph7041379
10. Font-Ribera L, Kogevinas M, Zock JP, Gomez FP, Barreiro E, Nieuwenhuijsen MJ, Fernandez P, Lourencetti C, Perez-Olabarria M, Bustamante M, Marcos R, Grimalt JO, Villanueva CM (2010) Short-term changes in respiratory biomarkers after swimming in a chlorinated pool. Environ Health Perspect 118(11):1538-1544. doi: 10.1289/ehp.1001961
11. Font-Ribera L, Villanueva CM, Nieuwenhuijsen MJ, Zock JP, Kogevinas M, Henderson J (2011) Swimming pool attendance, asthma, allergies, and lung function in the avon longitudinal study of parents and children cohort. Am J Respir Crit Care Med 183(5):582-588. doi: 10.1164/rccm.201005-0761OC
12. Garcia-Montoya IA, Cendon TS, Arevalo-Gallegos S, Rascon-Cruz Q (2011) Lactoferrin a multiple bioactive protein: an overview. Biochim Biophys Acta. doi: 10.1016/j.bbagen.2011.06.018
13. Ghafouri B, Stahlbom B, Tagesson C, Lindahl M (2002) Newly identified proteins in human nasal lavage fluid from non-smokers and smokers using two-dimensional gel electrophoresis and peptide mass fingerprinting. Proteomics 2(1):112-120
14. Ghafouri B, Kihlstrom E, Tagesson C, Lindahl M (2004) Plunc in human nasal lavage fluid: multiple isoforms that bind to lipopolysaccharide. Biochim Biophys Acta 1699(1-2):57-63. doi: 10.1016/j.bbapap.2004.01.001
15. Ghafouri B, Irander K, Lindbom J, Tagesson C, Lindahl M (2006) Comparative proteomics of nasal fluid in seasonal allergic rhinitis. J Proteome Res 5(2):330-338. doi: 10.1021/pr050341h
16. Ghafouri B, Karlsson H, Mortstedt H, Lewander A, Tagesson C, Lindahl M (2007) 2,5-dihydroxybenzoic acid instead of alpha-cyano-4-hydroxycinnamic acid as matrix in matrix-assisted laser desorption/ionization time-of-flight mass spectrometry for analyses of in-gel digests of silver-stained proteins. Anal Biochem 371(1):121-123. doi: 10.1016/j.ab.2007.07.002
17. Gharahdaghi F, Weinberg CR, Meagher DA, Imai BS, Mische SM (1999) Mass spectrometric identification of proteins from silver-stained polyacrylamide gel: a method for the removal of silver ions to enhance sensitivity. Electrophoresis 20(3):601-605
18. Gorg A, Obermaier C, Boguth G, Harder A, Scheibe B, Wildgruber R, Weiss W (2000) The current state of two-dimensional electrophoresis with immobilized ph gradients. Electrophoresis 21(6):1037-1053
19. Goyette J, Geczy CL (2010) Inflammation-associated s100 proteins: new mechanisms that regulate function. Amino Acids. doi: 10.1007/s00726-010-0528-0
20. Hery M, Hecht G, Gerber JM, Gender JC, Hubert G, Rebuffaud J (1995) Exposure to chloramines in the atmosphere of indoor swimming pools. Ann Occup Hyg 39(4):427-439
21. Hery M, Gerber JM, Hecht G, Subra I, Possoz C, Aubert S, Dieudonne M, Andre JC (1998) Exposure to chloramines in a green salad processing plant. Ann Occup Hyg 42(7):437-451
22. Jacobs JH, Spaan S, van Rooy GB, Meliefste C, Zaat VA, Rooyackers JM, Heederik D (2007) Exposure to trichloramine and respiratory symptoms in indoor swimming pool workers. Eur Respir J 29(4):690-698. doi: 10.1183/09031936. 00024706
23. Levesque B, Duchesne JF, Gingras S, Lavoie R, Prud'Homme D, Bernard E, Boulet LP, Ernst P (2006) The determinants of prevalence of health complaints among young competitive swimmers. Int Arch Occup Environ Health 80(1):32-39. doi: 10.1007/s00420-006-0100-0
24. Li CY, Sung FC (1999) A review of the healthy worker effect in occupational epidemiology. Occup Med (Lond) 49(4):225-229
25. Lindahl M, Irander K, Tagesson C, Stahlbom B (2004) Nasal lavage fluid and proteomics as means to identify the effects of the irritating epoxy chemical dimethylbenzylamine. Biomarkers 9(1):56-70. doi: 10.1080/13547500410001662005
26. Massin N, Bohadana AB, Wild P, Hery M, Toamain JP, Hubert G (1998) Respiratory symptoms and bronchial responsiveness in lifeguards exposed to nitrogen trichloride in indoor swimming pools. Occup Environ Med 55(4):258-263
27. Nemery B, Hoet PH, Nowak D (2002) Indoor swimming pools, water chlorination and respiratory health. Eur Respir J 19(5):790-793
28. Norback D, Wieslander G (2002) Biomarkers and chemosensory irritations. Int Arch Occup Environ Health 75(5):298-304. doi: 10.1007/s00420-002-0314-8
29. Packer NH, Lawson MA, Jardine DR, Sanchez JC, Gooley AA (1998) Analyzing glycoproteins separated by two-dimensional gel electrophoresis. Electrophoresis 19(6):981-988. doi: 10.1002/elps.1150190613
30. Richardson SD, DeMarini DM, Kogevinas M, Fernandez P, Marco E, Lourencetti C, Balleste C, Heederik D, Meliefste K, McKague AB, Marcos R, Font-Ribera L, Grimalt JO, Villanueva CM (2010) What's in the pool? A comprehensive identification of disinfection by-products and assessment of mutagenicity of chlorinated and brominated swimming pool water. Environ Health Perspect 118(11):1523-1530. doi: 10.1289/ehp.1001965
31. Schmalz C, Frimmel FH, Zwiener C (2011) Trichloramine in swimming pools-formation and mass transfer. Water Res 45(8):2681-2690. doi: 10.1016/j.watres.2011.02.024
32. Shevchenko A, Wilm M, Vorm O, Mann M (1996) Mass spectrometric sequencing of proteins silver-stained polyacrylamide gels. Anal Chem 68(5):850-858
33. Taylor DR, Pijnenburg MW, Smith AD, De Jongste JC (2006) Exhaled nitric oxide measurements: clinical application and interpretation. Thorax 61(9):817-827. doi: 10.1136/thx.2005.056093
34. Thickett KM, McCoach JS, Gerber JM, Sadhra S, Burge PS (2002) Occupational asthma caused by chloramines in indoor swimming-pool air. Eur Respir J 19(5):827-832
35. Vallyathan V, Goins M, Lapp LN, Pack D, Leonard S, Shi X, Castranova V (2000) Changes in bronchoalveolar lavage indices associated with radiographic classification in coal miners. Am J Respir Crit Care Med 162(3 Pt 1):958-965
36. van de Graaf EA, Out TA, Kobesen A, Jansen HM (1991) Lactoferrin and secretory iga in the bronchoalveolar lavage fluid from patients with a stable asthma. Lung 169(5):275-283
37. Vogl T, Tenbrock K, Ludwig S, Leukert N, Ehrhardt C, van Zoelen MA, Nacken W, Foell D, van der Poll T, Sorg C, Roth J (2007) Mrp8 and mrp14 are endogenous activators of toll-like receptor 4, promoting lethal, endotoxin-induced shock. Nat Med 13(9):1042-1049. doi: 10.1038/nm1638
38. Weaver WA, Li J, Wen Y, Johnston J, Blatchley MR, Blatchley ER 3rd (2009) Volatile disinfection by-product analysis from chlorinated indoor swimming pools. Water Res 43(13):3308-3318. doi: 10.1016/j.watres.2009.04.035
39. Wetmore BA, Merrick BA (2004) Toxicoproteomics: proteomics applied to toxicology and pathology. Toxicol Pathol 32(6):619-642
40. WHO (2006) Guidelines for safe recreational water environments. World Health Organization 2: swimming pools and similar environments: available: http://www.who.int/water-sanitation-health/bathing/srwe2full.pdf. Accessed 31 August 2011