Nasal lavage fluid and proteomics as means to identify the effects of the irritating epoxy chemical dimethylbenzylamine

Biomarkers

Volumn 9, Issue 1, 2004, Pages 56-70

  Lindahl, Mats ^a   Irander, Kristina ^a   Tagesson, Christer ^a   Ståhlbom, Bengt ^a  

^a LINKÖPING UNIVERSITY   (Sweden)

Author keywords

Dimethylbenzylamine; Epoxy; Mass spectrometry; Nasal lavage fluid; Proteomics

Indexed keywords

ALPHA 2 MACROGLOBULIN; BENZYLAMINE DERIVATIVE; BIOLOGICAL MARKER; CALGRANULIN; CERULOPLASMIN; CLARA CELL PROTEIN; DIMETHYLBENZ[A]ANTHRACENE; IMMUNOGLOBULIN A; IMMUNOGLOBULIN BINDING FACTOR; STATHERIN;

ADULT; AMINO TERMINAL SEQUENCE; ARTICLE; CHEMICAL ANALYSIS; CLINICAL ARTICLE; CONTROLLED STUDY; DATA BASE; EOSINOPHIL; FEMALE; HUMAN; LAVAGE; LEUKOCYTE COUNT; MALE; MASS SPECTROMETRY; NOSE MUCOSA; NOSE MUCUS; OCCUPATIONAL EXPOSURE; PROTEIN ANALYSIS; PROTEOMICS; RESPIRATORY TRACT DISEASE; RESPIRATORY TRACT INFLAMMATION; TWO DIMENSIONAL GEL ELECTROPHORESIS;

9,10-DIMETHYL-1,2-BENZANTHRACENE; ADULT; ALPHA-MACROGLOBULINS; CALGRANULIN B; CARCINOGENS; CERULOPLASMIN; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; EOSINOPHILS; HUMANS; INDUSTRY; MASS SPECTROMETRY; MIDDLE AGED; NASAL LAVAGE FLUID; NASAL MUCOSA; OCCUPATIONAL EXPOSURE; PROTEIN STRUCTURE, TERTIARY; PROTEOME; PROTEOMICS; SALIVARY PROTEINS; SMOKING; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 2442640456     PISSN: 1354750X     EISSN: None     Source Type: Journal    
DOI: 10.1080/13547500410001662005     Document Type: Article

References (47)

1. Banks, R. E., Dunn, M. J., Hochstrasser, D. F., Sanchez, J.-C., Pappin, D. J. and Selby, P. J. 2000, Proteomics: new perspectives, new biomedical opportunities. Lancet, 356, 1749-1756.
2. Bernard, A. and Lauwerys, R. 1995, Low-molecular-weight proteins as markers of organ toxicity with special reference to Clara cell protein. Toxicology Letters, 77, 145-151.
3. Bjellqvist, B., Basse, B., Olsen, E. and Celis, J. E. 1994, Reference points for comparison of two-dimensional maps of proteins from different human cell types defined in a pH scale where isoelectric points correlate with polypeptide composition. Electrophoresis, 15, 529-539.
4. Bradford, M. 1976, A rapid and sensitive method for the quantification of microgram quantities of protein utilising the principle of protein-dye binding. Analytical Biochemistry, 72, 248-252.
5. Carbonnelle, S., Francaux, M., Doyle, I., Dumont, X., De Burbure, C., Morel, G., Michel, O. and Bernard, A. 2002, Changes in serum pneumoproteins caused by short-term exposures to nitrogen trichloride in indoor chlorinated swimming pools. Biomarkers, 7, 464-478.
6. Cole, A. M., Dewan, P. and Ganz, T. 1999, Innate antimicrobial activity of nasal secretions. Infection and Immunity, 67, 3267-3275.
7. Cole, A. M., Liao, H.-I., Stuchlik, O., Tilan, J., Pohl, J. and Ganz, T. 2002, Cationic polypeptides are required for antibacterial activity of human airway fluid. Journal of Immunology, 169, 6985-6991.
8. Donato, R. 2001, S100: a multigenic family of calcium-modulated proteins of the EF-hand type with intracellular and extracellular functional roles. International Journal of Biochemistry and Cell Biology, 33, 637-668.
9. Ghafouri, B., Ståhlbom, B., Tagesson, C. and Lindahl, M. 2002, Newly identified proteins in human nasal lavage fluid from non-smokers and smokers using two-dimensional gel electrophoresis and peptide mass fingerprinting. Proteomics, 2, 112-120.
10. Ghafouri, B., Kihlström, E., Ståhlbom, B., Tagesson, C. and Lindahl, M. 2003, PLUNC (palate, lung and nasal epithelial clone) proteins in human nasal lavage fluid. Biochemical Society Transactions, 31, 810-814.
11. Görg, A., Obermaier, C., Boguth, G., Harder, A., Scheibe, B., Wildgruber, R. and Weiss, W. 2000, The current state of two-dimensional gel electrophoresis with immobilized pH gradients. Electrophoresis, 21, 1037-1053.
12. Grandstrand, P., Nylander-French, L. and Holmström, M. 1998, Biomarkers of nasal inflammation in wood-surface coating industry workers. American Journal of Industrial Medicine, 33, 392-399.
13. Greiff, L., Pipkorn, U., Alkner, U. and Persson, C. G. 1990, The nasal pool device applies controlled concentrations of solutes on human airway mucosa and samples its surface exudations/secretions. Clinical and Experimental Allergy, 20, 253-259.
14. Hochstrasser, D. F. 1998, Proteome in perspective. Clinical Chemistry and Laboratory Medicine, 36, 825-836.
15. Irander, K., Ståhlbom, B., Wellinder, H. and Åkesson, B. 1997, Methachromatic cells and eosinphils in the nasal mucosa and N,N-dimethylbenzylamine exposure. Acta Oto-laryngologica, 117, 433-436.
16. Jensen, J. L., Uhlig, T., Kvien, T. K. and Axell, T. 1997, Characteristics of rheumatoid arthritis patients with self-reported sicca symptoms: evaluation of medical, salivary and oral parameters. Oral Diseases, 3, 254-261.
17. 2 inhibitor, in acute lung injury. European Respiratory Journal, 8, 1647-1653.
18. Kamada, M., Mori, H., Maeda, N., Yamamoto, S., Kunimi, K., Takikawa, M., Maegawa, M., Aono, T., Futaki, S. and Koide, S. S. 1998, β-Microseminoprotein/prostatic secretory protein is a member of immunoglobulin binding factor family. Biochimica et Biophysica Acta, 1388, 101-110.
19. Kennedy, S. 2002, The role of proteomics in toxicology: identification of biomarkers of toxicity by protein expression analysis. Biomarkers, 7, 269-290.
20. Kerkhoff, C., Klempt, M. and Song, C. 1998, Novel insights into structure and function of MRP8 (S100A8) and MRP9 (S100A9). Biochimica et Biophysica Acta, 1448, 200-211.
21. Kerkhoff, C., Klempt, M., Kaever, V. and Sorg, C. 1999, The two calcium-binding proteins, S100A8 and S100A9, are involved in the metabolism of arachidonic acid in human neutrophils. Journal of Biological Chemistry, 12, 32672-32679.
22. Lensmar, C., Nord, M., Gudmunsson, G. H., Roquet, A., Andersson, O., Jornvall, H., Eklund, A., Grunewald, J. and Agerberth, B. 2000, Decreased pulmonary levels of the anti-inflammatory Clara cell 16 kDa protein after induction of airway inflammation in asthmatics. Cellular and Molecular Life Sciences, 57, 976-981.
23. Lindahl, M., Ståhlbom, B. and Tagesson, C. 1995, Two-dimensional gel electrophoresis of nasal and bronchoalveolar lavage fluids after occupational exposure. Electrophoresis, 16, 1199-1204.
24. Lindahl, M., Ekström, T., Sörensen, J. and Tagesson, C. 1996, Two-dimensional protein patterns of bronchoalveolar lavage fluid from non-smokers, smokers, and subjects exposed to asbestos. Thorax, 51, 1028-1035.
25. Lindahl, M., Ståhlbom, B., Svartz, J. and Tagesson, C. 1998, Protein patterns of human nasal and bronchoalvolar lavage fluids analyzed with two-dimensional gel electrophoresis. Electrophoresis, 19, 3222-3229.
26. Lindahl, M., Ståhlbom, B. and Tagesson, C. 1999a, Newly identified proteins in human nasal and bronchoalvolar lavage fluids: potential biomedical and clinical applications. Electrophoresis, 20, 3670-3676.
27. Lindahl, M., Svartz, J. and Tagesson, C. 1999b, Demonstration of different forms of the anti-inflammatory proteins lipocortin-1 and Clara cell protein-16 in human and bronchoalveolar lavage fluids. Electrophoresis, 20, 881-890.
28. Lindahl, M., Ståhlbom, B. and Tagesson, C. 2001, Identification of a new potential airway irritation marker, palate lung nasal epithelial clone protein, in human nasal lavage fluid with two-dimensional electrophoresis and matrix-assisted laser desorption/ionisation-time of flight. Electrophoresis, 22, 1795-1800.
29. Long, J. R., Shaw, W. J., Stayton, P. S. and Drobny, G. P. 2001, Structure and dynamics of hydrated statherin on hydroxyapatite as determined by solid-state NMR. Biochemistry, 40, 15451-15455.
30. Longbottom, D., Sallenave, J. M. and van Heyningen, V. 1992, Subunit structure of calgranulins A and B obtained from sputum, plasma granulocytes and cultured epithelial cells. Biochimica et Biophysica Acta, 1120, 215-222.
31. Nielsen, J., Welinder, H., Ottosson, H., Bensryd, I., Venge, P. and Skerfving, S. 1994, Nasal challenge shows pathogenic relevance of specific IgE serum antibodies for nasal symptoms caused by hexahydrophthalic anhydride. Clinical and Experimental Allergy, 24, 440-449.
32. Noel-Georis, I., Bernard, A., Falmagne, P. and Wattiez, R. 2001, Proteomics as the tool to search for lung disease markers in bronchoalveolar lavage. Disease Markers, 17, 271-284.
33. Norbäck, D. and Wieslander, G. 2002, Biomarkers and chemosensory irritations. International Archives of Occupational and Environmental Health, 75, 298-304.
34. Ogushi, F., Sone, S., Tani, K., Takehara, H., Endo, T., Haku, T., Nakamura, Y., Ogura, T., Kamada, M. and Aono, T. 1995, Identification and localization of immunoglobulin binding factor in bronchoalveolar lavage fluid from healthy smokers. American Journal of Respiratory and Critical Care Medicine, 152, 2133-2137.
35. Oyama, Y., Shishibori, T., Yamashita, K., Naya, T., Nakagiri, S., Maeta, H. and Kobayashi, R. 1997, Two distinct anti-allergic drugs, amlexanox and cromolyn, bind to the same kinds of calcium binding proteins, except calmodulin, in bovine lung extract. Biochemical and Biophysical Research Communications, 240, 341-347.
36. Passalacqua, G., Ciprandi, G. and Canonica, G. W. 2000, United airways disease: therapeutic aspects. Thorax, 55, S26-S27.
37. Petrek, M., Hermans, C., Kolek, V., Fialova, J. and Bernard, A. 2002, Clara cell protein (CC16) in serum and bronchoalveolar lavage fluid of subjects exposed to asbestos. Biomarkers, 7, 58-67.
38. Sanchez, J.-C., Appel, R. D., Golaz, O., Pasquali, C., Ravier, F., Bairoch, A. and Hochstrasser, D. F. 1995, Inside SWISS-2DPAGE database. Electrophoresis, 16, 1131-1151.
39. Ståhlbom, B., Åkesson, B. and Jönsson, B. 1997, Experimental human exposure to N-dimethyl-benzylamine: generation of a controlled atmosphere and biological monitoring. International Archives of Occupational and Environmental Health, 70, 393-398.
40. Steiner, S. and Anderson, N. L. 2000, Expression profiling in toxicology - potential and limitations. Toxicology Letters, 15, 467-471.
41. Swain, M. and Ross, N. W. 1995, A silver stain protocol for proteins yielding high resolution and transparent background in sodium dodecyl sulfate-polyacrylamide gels. Electrophoresis, 16, 948-951.
42. van Heyningen, V. and Dorin, J. 1990, Possible role for two calcium-binding proteins of the S-100 family, co-expressed in granulocytes and certain epithelia. Advances in Experimental Medicine and Biology, 269, 139-143.
43. Vesterberg, O., Palmberg, L. and Larsson, K. 2001, Albumin, transferrin and (α2-macroglobulin in bronchoalveolar lavage fluid following exposure to organic dust in healthy subjects. International Archives of Occupational and Environmental Health, 74, 249-254.
44. Vignola, A. M., Chanez, P., Godard, P. and Bousquet, J. 1998, Relationships between rhinits and asthma. Allergy, 53, 833-839.
45. Wattiez, R., Hermans, C., Cruyt, C., Bernard, A. and Falmagne, P. 2000, Human bronchoalveolar lavage fluid protein two-dimensional database: a study of interstitial lung diseases. Electrophoresis, 21, 2703-2712.
46. Welinder, H., Jönsson, B., Nielsen, J., Ottosson, H. E. and Gustavsson, C. A. 1994, Exposure-response relationships in the formation of specific antibodies to hexahydrophthalic anhydride in exposed workers. Scandinavian Journal of Work and Environmental Health, 20, 459-465.
47. Wilkins, M. R. and Gooley, A. A. 1997, Protein identification in proteome projects. In Proteome Research: New Frontiers in Functional Genomics, edited by M. R. Wilkins, K. L. Williams, R. D. Appel and D. F. Hochstrasser (Berlin: Springer-Verlag), pp. 35-64.