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Volumn 8, Issue 1, 2013, Pages

Bcr-Abl tyrosine kinase inhibitors-current status

Author keywords

[No Author keywords available]

Indexed keywords

1,3,4 THIADIAZOLE DERIVATIVE; ABELSON KINASE; BAFETINIB; BCR ABL PROTEIN; BOSUTINIB; CARBOXYLIC ACID; DASATINIB; IMATINIB; ISOLEUCINE; METHYL GROUP; MULTIDRUG RESISTANCE PROTEIN; NILOTINIB; PONATINIB; PROTEIN TYROSINE KINASE INHIBITOR;

EID: 84879094568     PISSN: None     EISSN: 17509378     Source Type: Journal    
DOI: 10.1186/1750-9378-8-23     Document Type: Article
Times cited : (26)

References (28)
  • 3
    • 0021674862 scopus 로고
    • An alteration of the human c-abl protein in K562 leukemia cells unmasks associated tyrosine kinase activity
    • 10.1016/0092-8674(84)90438-0 6204766
    • An alteration of the human c-abl protein in K562 leukemia cells unmasks associated tyrosine kinase activity. Konopka JB, Watanabe SM, Witte ON, Cell 1984 37 3 1035 10.1016/0092-8674(84)90438-0 6204766
    • (1984) Cell , vol.37 , Issue.3 , pp. 1035
    • Konopka, J.B.1    Watanabe, S.M.2    Witte, O.N.3
  • 4
    • 84880148865 scopus 로고    scopus 로고
    • A new consistent chromosomal adnormality in chronic myelogeneus leukaemia identified by quinacrine fluorescence and Giemsa staining
    • A new consistent chromosomal adnormality in chronic myelogeneus leukaemia identified by quinacrine fluorescence and Giemsa staining. Rowley JD, Landmarks in Medical Genetics: Classic Papers with Commentaries 2004 243 51 104
    • (2004) Landmarks in Medical Genetics: Classic Papers with Commentaries , vol.243 , Issue.51 , pp. 104
    • Rowley, J.D.1
  • 5
    • 0028256425 scopus 로고
    • Inhibition of apoptosis by BCR-ABL in chronic myeloid leukemia
    • Inhibition of apoptosis by BCR-ABL in chronic myeloid leukemia. Bedi A, Zehnbauer BA, Barber JP, Sharkis S, Jones R, Blood 1994 83 8 2038 2044 8161775 (Pubitemid 24112713)
    • (1994) Blood , vol.83 , Issue.8 , pp. 2038-2044
    • Bedi, A.1    Zehnbauer, B.A.2    Barber, J.P.3    Sharkis, S.J.4    Jones, R.J.5
  • 6
    • 0032556921 scopus 로고    scopus 로고
    • BCR-ABL activates pathways mediating cytokine independence and protection against apoptosis in murine hematopoietic cells in a dose-dependent manner
    • 10.1038/sj.onc.1201490 9467959
    • BCR-ABL activates pathways mediating cytokine independence and protection against apoptosis in murine hematopoietic cells in a dose-dependent manner. Cambier N, Chopra R, Strasser A, Metcalf D, Elefanty AG, Oncogene 1998 16 3 335 10.1038/sj.onc.1201490 9467959
    • (1998) Oncogene , vol.16 , Issue.3 , pp. 335
    • Cambier, N.1    Chopra, R.2    Strasser, A.3    Metcalf, D.4    Elefanty, A.G.5
  • 7
    • 0030471795 scopus 로고    scopus 로고
    • The BCR-ABL tyrosine kinase inhibits apoptosis by activating a Ras-dependent signaling pathway
    • 9000132
    • The BCR-ABL tyrosine kinase inhibits apoptosis by activating a Ras-dependent signaling pathway. Cortez D, Stoica G, Pierce JH, Pendergast AM, Oncogene 1996 13 12 2589 9000132
    • (1996) Oncogene , vol.13 , Issue.12 , pp. 2589
    • Cortez, D.1    Stoica, G.2    Pierce, J.H.3    Pendergast, A.M.4
  • 8
    • 0030038231 scopus 로고    scopus 로고
    • Bcr/Abl expression stimulates integrin function in hematopoietic cell lines
    • 10.1172/JCI118820 8755665
    • Bcr/Abl expression stimulates integrin function in hematopoietic cell lines. Bazzoni G, Carlesso N, Griffin JD, Hemler ME, J Clin Investig 1996 98 2 521 10.1172/JCI118820 8755665
    • (1996) J Clin Investig , vol.98 , Issue.2 , pp. 521
    • Bazzoni, G.1    Carlesso, N.2    Griffin, J.D.3    Hemler, M.E.4
  • 9
    • 0003345351 scopus 로고    scopus 로고
    • Presence of the adhesion inhibitory β1B integrin isoform on CML but not normal progenitors is at least in part responsible for the decreased CML progenitor adhesion
    • Presence of the adhesion inhibitory β1B integrin isoform on CML but not normal progenitors is at least in part responsible for the decreased CML progenitor adhesion. Zhao R, Tarone G, Verfaillie C, Blood 1997 90 Suppl 1 393a
    • (1997) Blood , vol.90 , Issue.SUPPL. 1
    • Zhao, R.1    Tarone, G.2    Verfaillie, C.3
  • 10
    • 0025348013 scopus 로고
    • Tyrosine kinase activity and transformation potency of bcr-abl oncogene products
    • 10.1126/science.2408149
    • Tyrosine kinase activity and transformation potency of bcr-abl oncogene products. Lugo TG, Pendergast A-M, Muller AJ, Witte ON, Science (New York, NY) 1990 247 4946 1079 10.1126/science.2408149
    • (1990) Science (New York, NY) , vol.247 , Issue.4946 , pp. 1079
    • Lugo, T.G.1    Pendergast, A.-M.2    Muller, A.J.3    Witte, O.N.4
  • 11
    • 0028980342 scopus 로고
    • Structural and signaling requirements for BCR-ABL-mediated transformation and inhibition of apoptosis
    • 7565705
    • Structural and signaling requirements for BCR-ABL-mediated transformation and inhibition of apoptosis. Cortez D, Kadlec L, Pendergast AM, Mol Cell Biol 1995 15 10 5531 5541 7565705
    • (1995) Mol Cell Biol , vol.15 , Issue.10 , pp. 5531-5541
    • Cortez, D.1    Kadlec, L.2    Pendergast, A.M.3
  • 12
    • 77749288978 scopus 로고    scopus 로고
    • Mechanisms of resistance to tyrosine kinase inhibitors in chronic myeloid leukemia and recent therapeutic strategies to overcome resistance
    • Mechanisms of resistance to tyrosine kinase inhibitors in chronic myeloid leukemia and recent therapeutic strategies to overcome resistance. Bixby D, Talpaz M, ASH Education Program Book 2009 2009 1 461 476
    • (2009) ASH Education Program Book , vol.2009 , Issue.1 , pp. 461-476
    • Bixby, D.1    Talpaz, M.2
  • 14
    • 31344435118 scopus 로고    scopus 로고
    • Design and synthesis of 3-substituted benzamide derivatives as Bcr-Abl kinase inhibitors
    • DOI 10.1016/j.bmcl.2005.11.042, PII S0960894X05014538
    • Design and synthesis of 3-substituted benzamide derivatives as Bcr-Abl kinase inhibitors. Asaki T, Sugiyama Y, Hamamoto T, Higashioka M, Umehara M, Naito H, Niwa T, Bioorg Med Chem Lett 2006 16 5 1421 1425 10.1016/j.bmcl.2005. 11.042 16332440 (Pubitemid 43143035)
    • (2006) Bioorganic and Medicinal Chemistry Letters , vol.16 , Issue.5 , pp. 1421-1425
    • Asaki, T.1    Sugiyama, Y.2    Hamamoto, T.3    Higashioka, M.4    Umehara, M.5    Naito, H.6    Niwa, T.7
  • 15
    • 63749090203 scopus 로고    scopus 로고
    • The interplay of structural information and functional studies in kinase drug design: Insights from BCR-Abl
    • 10.1016/j.ceb.2009.01.014 19217274
    • The interplay of structural information and functional studies in kinase drug design: insights from BCR-Abl. Eck MJ, Manley PW, Curr Opin Cell Biol 2009 21 2 288 10.1016/j.ceb.2009.01.014 19217274
    • (2009) Curr Opin Cell Biol , vol.21 , Issue.2 , pp. 288
    • Eck, M.J.1    Manley, P.W.2
  • 16
    • 77955985510 scopus 로고    scopus 로고
    • BCR-ABL tyrosine kinase inhibitors in the treatment of Philadelphia chromosome positive chronic myeloid leukemia: A review
    • 10.1016/j.leukres.2010.04.016 20537386
    • BCR-ABL tyrosine kinase inhibitors in the treatment of Philadelphia chromosome positive chronic myeloid leukemia: a review. An X, Tiwari AK, Sun Y, Ding P-R, Ashby CR, Chen Z-S, Leuk Res 2010 34 10 1255 1268 10.1016/j.leukres. 2010.04.016 20537386
    • (2010) Leuk Res , vol.34 , Issue.10 , pp. 1255-1268
    • An, X.1    Tiwari, A.K.2    Sun, Y.3    Ding, P.-R.4    Ashby, C.R.5    Chen, Z.-S.6
  • 17
    • 77954794865 scopus 로고    scopus 로고
    • Treatment options for patients with chronic myeloid leukemia who are resistant to or unable to tolerate imatinib
    • 10.1016/j.clinthera.2010.05.003 20685492
    • Treatment options for patients with chronic myeloid leukemia who are resistant to or unable to tolerate imatinib. Stein B, Douglas Smith B, Clin Ther 2010 32 5 804 820 10.1016/j.clinthera.2010.05.003 20685492
    • (2010) Clin Ther , vol.32 , Issue.5 , pp. 804-820
    • Stein, B.1    Douglas Smith, B.2
  • 18
    • 9444282642 scopus 로고    scopus 로고
    • Active transport of imatinib into and out of cells: Implications for drug resistance
    • DOI 10.1182/blood-2003-12-4276
    • Active transport of imatinib into and out of cells: implications for drug resistance. Thomas J, Wang L, Clark RE, Pirmohamed M, Blood 2004 104 12 3739 3745 10.1182/blood-2003-12-4276 15315971 (Pubitemid 39564452)
    • (2004) Blood , vol.104 , Issue.12 , pp. 3739-3745
    • Thomas, J.1    Wang, L.2    Clark, R.E.3    Pirmohamed, M.4
  • 19
    • 79959371494 scopus 로고    scopus 로고
    • Nilotinib for the treatment of chronic myeloid leukemia: An evidence-based review
    • Nilotinib for the treatment of chronic myeloid leukemia: An evidence-based review. Jabbour E, Cortes J, Kantarjian H, Core evidence 2009 4 207
    • (2009) Core Evidence , vol.4 , pp. 207
    • Jabbour, E.1    Cortes, J.2    Kantarjian, H.3
  • 20
    • 29144464371 scopus 로고    scopus 로고
    • Advances in the structural biology, design and clinical development of Bcr-Abl kinase inhibitors for the treatment of chronic myeloid leukaemia
    • DOI 10.1016/j.bbapap.2005.07.040, PII S1570963905003018
    • Advances in the structural biology, design and clinical development of Bcr-Abl kinase inhibitors for the treatment of chronic myeloid leukaemia. Manley PW, Cowan-Jacob SW, Mestan J, Biochim Biophys Acta 2005 1754 1-2 3 13 16172030 (Pubitemid 41797682)
    • (2005) Biochimica et Biophysica Acta - Proteins and Proteomics , vol.1754 , Issue.1-2 , pp. 3-13
    • Manley, P.W.1    Cowan-Jacob, S.W.2    Mestan, J.3
  • 21
    • 77956649599 scopus 로고    scopus 로고
    • Structural resemblances and comparisons of the relative pharmacological properties of imatinib and nilotinib
    • 10.1016/j.bmc.2010.08.026 20817538
    • Structural resemblances and comparisons of the relative pharmacological properties of imatinib and nilotinib. Manley PW, Stiefl N, Cowan-Jacob SW, Kaufman S, Mestan J, Wartmann M, Wiesmann M, Woodman R, Gallagher N, Bioorg Med Chem 2010 18 19 6977 6986 10.1016/j.bmc.2010.08.026 20817538
    • (2010) Bioorg Med Chem , vol.18 , Issue.19 , pp. 6977-6986
    • Manley, P.W.1    Stiefl, N.2    Cowan-Jacob, S.W.3    Kaufman, S.4    Mestan, J.5    Wartmann, M.6    Wiesmann, M.7    Woodman, R.8    Gallagher, N.9
  • 22
    • 74849116614 scopus 로고    scopus 로고
    • Nilotinib: A second-generation tyrosine kinase inhibitor for chronic myeloid leukemia
    • 10.1016/j.leukres.2009.08.031 19783301
    • Nilotinib: a second-generation tyrosine kinase inhibitor for chronic myeloid leukemia. Breccia M, Alimena G, Leuk Res 2010 34 2 129 134 10.1016/j.leukres.2009.08.031 19783301
    • (2010) Leuk Res , vol.34 , Issue.2 , pp. 129-134
    • Breccia, M.1    Alimena, G.2
  • 23
    • 35748952533 scopus 로고    scopus 로고
    • Dasatinib: A new step in molecular target therapy
    • 17591830
    • Dasatinib: a new step in molecular target therapy. Olivieri A, Manzione L, Ann Oncol 2007 18 suppl 6 22i42 vi46 17591830
    • (2007) Ann Oncol , vol.18 , Issue.SUPPL. 6
    • Olivieri, A.1    Manzione, L.2
  • 26
    • 34247381158 scopus 로고    scopus 로고
    • Structural factors contributing to the Abl/Lyn dual inhibitory activity of 3-substituted benzamide derivatives
    • DOI 10.1016/j.bmcl.2007.03.002, PII S0960894X07002910
    • Structural factors contributing to the Abl/Lyn dual inhibitory activity of 3-substituted benzamide derivatives. Horio T, Hamasaki T, Inoue T, Wakayama T, Itou S, Naito H, Asaki T, Hayase H, Niwa T, Bioorg Med Chem Lett 2007 17 10 2712 2717 10.1016/j.bmcl.2007.03.002 17376680 (Pubitemid 46636265)
    • (2007) Bioorganic and Medicinal Chemistry Letters , vol.17 , Issue.10 , pp. 2712-2717
    • Horio, T.1    Hamasaki, T.2    Inoue, T.3    Wakayama, T.4    Itou, S.5    Naito, H.6    Asaki, T.7    Hayase, H.8    Niwa, T.9
  • 28
    • 77956502134 scopus 로고    scopus 로고
    • Standard treatment of Ph+ CML in 2010: How, when and where not to use what BCR/ABL1 kinase inhibitor?
    • 10.1111/j.1365-2362.2010.02328.x
    • Standard treatment of Ph+ CML in 2010: how, when and where not to use what BCR/ABL1 kinase inhibitor? Valent P, Eur J Clin Investig 2010 40 10 918 931 10.1111/j.1365-2362.2010.02328.x
    • (2010) Eur J Clin Investig , vol.40 , Issue.10 , pp. 918-931
    • Valent, P.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.