-
1
-
-
0034603799
-
Genetic determinants of hemostasis phenotypes in spanish families
-
Souto JC, Almasy L, Borrell M, Garí M, Martínez E, Mateo J, Stone WH, Blangero J, Fontcuberta J. Genetic determinants of hemostasis phenotypes in Spanish families. Circulation. 2000;101:1546-1551.
-
(2000)
Circulation
, vol.101
, pp. 1546-1551
-
-
Souto, J.C.1
Almasy, L.2
Borrell, M.3
Garí, M.4
Martínez, E.5
Mateo, J.6
Stone, W.H.7
Blangero, J.8
Fontcuberta, J.9
-
2
-
-
13244287947
-
Familial segregation of venous thromboembolism
-
Heit JA, Phelps MA, Ward SA, Slusser JP, Petterson TM, De Andrade M. Familial segregation of venous thromboembolism. J Thromb Haemost. 2004;2:731-736.
-
(2004)
J Thromb Haemost
, vol.2
, pp. 731-736
-
-
Heit, J.A.1
Phelps, M.A.2
Ward, S.A.3
Slusser, J.P.4
Petterson, T.M.5
De Andrade, M.6
-
3
-
-
58849093978
-
Heritability of plasma concentrations of activated protein c in a spanish population
-
Soria JM, Navarro S, Medina P, Souto R, Buil A, Estellés A, Fontcuberta J, España F. Heritability of plasma concentrations of activated protein C in a Spanish population. Blood Coagul Fibrinolysis. 2009;20:17-21.
-
(2009)
Blood Coagul Fibrinolysis
, vol.20
, pp. 17-21
-
-
Soria, J.M.1
Navarro, S.2
Medina, P.3
Souto, R.4
Buil, A.5
Estellés, A.6
Fontcuberta, J.7
España, F.8
-
4
-
-
0034059213
-
The endothelial cell protein c receptor
-
Esmon CT. The endothelial cell protein C receptor. Thromb Haemost. 2000;83:639-643.
-
(2000)
Thromb Haemost
, vol.83
, pp. 639-643
-
-
Esmon, C.T.1
-
5
-
-
0019789514
-
Deficiency of protein c in congenital thrombotic disease
-
Griffin JH, Evatt B, Zimmerman TS, Kleiss AJ, Wideman C. Deficiency of protein C in congenital thrombotic disease. J Clin Invest. 1981;68:1370-1373.
-
(1981)
J Clin Invest
, vol.68
, pp. 1370-1373
-
-
Griffin, J.H.1
Evatt, B.2
Zimmerman, T.S.3
Kleiss, A.J.4
Wideman, C.5
-
6
-
-
0032879431
-
Inflammation, sepsis, and coagulation
-
Esmon CT, Fukudome K, Mather T, Bode W, Regan LM, Stearns-Kurosawa DJ, Kurosawa S. Inflammation, sepsis, and coagulation. Haematologica. 1999;84:254-259.
-
(1999)
Haematologica
, vol.84
, pp. 254-259
-
-
Esmon, C.T.1
Fukudome, K.2
Mather, T.3
Bode, W.4
Regan, L.M.5
Stearns-Kurosawa, D.J.6
Kurosawa, S.7
-
7
-
-
17144369480
-
The multifunctional protein c system
-
Espana F, Medina P, Navarro S, Zorio E, Estellés A, Aznar J. The multifunctional protein C system. Curr Med Chem Cardiovasc Hematol Agents. 2005;3:119-131.
-
(2005)
Curr Med Chem Cardiovasc Hematol Agents
, vol.3
, pp. 119-131
-
-
Espana, F.1
Medina, P.2
Navarro, S.3
Zorio, E.4
Estellés, A.5
Aznar, J.6
-
8
-
-
84865496914
-
Thrombomodulin protects endothelial cells from a calcineurin inhibitorinduced cytotoxicity by upregulation of extracellular signal-regulated kinase/myeloid leukemia cell-1 signaling
-
Ikezoe T, Yang J, Nishioka C, Honda G, Furihata M, Yokoyama A. Thrombomodulin protects endothelial cells from a calcineurin inhibitorinduced cytotoxicity by upregulation of extracellular signal-regulated kinase/myeloid leukemia cell-1 signaling. Arterioscler Thromb Vasc Biol. 2012;32:2259-2270.
-
(2012)
Arterioscler Thromb Vasc Biol
, vol.32
, pp. 2259-2270
-
-
Ikezoe, T.1
Yang, J.2
Nishioka, C.3
Honda, G.4
Furihata, M.5
Yokoyama, A.6
-
9
-
-
80054951313
-
Therapeutic angiogenesis of human early endothelial progenitor cells is enhanced by thrombomodulin
-
Li JY, Su CH, Wu YJ, Tien TY, Hsieh CL, Chen CH, Tseng YM, Shi GY, Wu HL, Tsai CH, Lin FY, Yeh HI. Therapeutic angiogenesis of human early endothelial progenitor cells is enhanced by thrombomodulin. Arterioscler Thromb Vasc Biol. 2011;31:2518-2525.
-
(2011)
Arterioscler Thromb Vasc Biol
, vol.31
, pp. 2518-2525
-
-
Li, J.Y.1
Su, C.H.2
Wu, Y.J.3
Tien, T.Y.4
Hsieh, C.L.5
Chen, C.H.6
Tseng, Y.M.7
Shi, G.Y.8
Wu, H.L.9
Tsai, C.H.10
Lin, F.Y.11
Yeh, H.I.12
-
10
-
-
0032080409
-
A targeted point mutation in thrombomodulin generates viable mice with a prethrombotic state
-
Weiler-Guettler H, Christie PD, Beeler DL, Healy AM, Hancock WW, Rayburn H, Edelberg JM, Rosenberg RD. A targeted point mutation in thrombomodulin generates viable mice with a prethrombotic state. J Clin Invest. 1998;101:1983-1991.
-
(1998)
J Clin Invest
, vol.101
, pp. 1983-1991
-
-
Weiler-Guettler, H.1
Christie, P.D.2
Beeler, D.L.3
Healy, A.M.4
Hancock, W.W.5
Rayburn, H.6
Edelberg, J.M.7
Rosenberg, R.D.8
-
11
-
-
0034892611
-
Endothelium-specific loss of murine thrombomodulin disrupts the protein c anticoagulant pathway and causes juvenile-onset thrombosis
-
Isermann B, Hendrickson SB, Zogg M, Wing M, Cummiskey M, Kisanuki YY, Yanagisawa M, Weiler H. Endothelium-specific loss of murine thrombomodulin disrupts the protein C anticoagulant pathway and causes juvenile-onset thrombosis. J Clin Invest. 2001;108:537-546.
-
(2001)
J Clin Invest
, vol.108
, pp. 537-546
-
-
Isermann, B.1
Hendrickson, S.B.2
Zogg, M.3
Wing, M.4
Cummiskey, M.5
Kisanuki, Y.Y.6
Yanagisawa, M.7
Weiler, H.8
-
12
-
-
80054905522
-
Human thrombomodulin knock-in mice reveal differential effects of human thrombomodulin on thrombosis and atherosclerosis
-
Raife TJ, Dwyre DM, Stevens JW, Erger RA, Leo L, Wilson KM, Fernández JA, Wilder J, Kim HS, Griffin JH, Maeda N, Lentz SR. Human thrombomodulin knock-in mice reveal differential effects of human thrombomodulin on thrombosis and atherosclerosis. Arterioscler Thromb Vasc Biol. 2011;31:2509-2517.
-
(2011)
Arterioscler Thromb Vasc Biol
, vol.31
, pp. 2509-2517
-
-
Raife, T.J.1
Dwyre, D.M.2
Stevens, J.W.3
Erger, R.A.4
Leo, L.5
Wilson, K.M.6
Fernández, J.A.7
Wilder, J.8
Kim, H.S.9
Griffin, J.H.10
Maeda, N.11
Lentz, S.R.12
-
13
-
-
0022396035
-
Thrombomodulin is present in human plasma and urine
-
Ishii H, Majerus PW. Thrombomodulin is present in human plasma and urine. J Clin Invest. 1985;76:2178-2181.
-
(1985)
J Clin Invest
, vol.76
, pp. 2178-2181
-
-
Ishii, H.1
Majerus, P.W.2
-
14
-
-
0025241217
-
Plasma thrombomodulin in health and diseases
-
Takano S, Kimura S, Ohdama S, Aoki N. Plasma thrombomodulin in health and diseases. Blood. 1990;76:2024-2029.
-
(1990)
Blood
, vol.76
, pp. 2024-2029
-
-
Takano, S.1
Kimura, S.2
Ohdama, S.3
Aoki, N.4
-
15
-
-
23844451164
-
Soluble thrombomodulin activity and soluble thrombomodulin antigen in plasma
-
Ohlin AK, Larsson K, Hansson M. Soluble thrombomodulin activity and soluble thrombomodulin antigen in plasma. J Thromb Haemost. 2005;3:976-982.
-
(2005)
J Thromb Haemost
, vol.3
, pp. 976-982
-
-
Ohlin, A.K.1
Larsson, K.2
Hansson, M.3
-
16
-
-
0011376542
-
Plasma thrombomodulin concentrations in healthy persons depends on age and sex
-
(Abstract)
-
Loreth RM, Seus Ch, Berger HH, Albert FW. Plasma thrombomodulin concentrations in healthy persons depends on age and sex. Ann Hematol. 1997;74(suppl II):A89 (Abstract).
-
(1997)
Ann Hematol
, vol.74
, Issue.SUPPL. II
-
-
Loreth, R.M.1
Seus, Ch.2
Berger, H.H.3
Albert, F.W.4
-
17
-
-
0028031435
-
Design and validation of a new immunoassay for soluble forms of thrombomodulin and studies on plasma
-
Amiral J, Adam M, Mimilla F, Larrivaz I, Chambrette B, Boffa MC. Design and validation of a new immunoassay for soluble forms of thrombomodulin and studies on plasma. Hybridoma. 1994;13:205-213.
-
(1994)
Hybridoma
, vol.13
, pp. 205-213
-
-
Amiral, J.1
Adam, M.2
Mimilla, F.3
Larrivaz, I.4
Chambrette, B.5
Boffa, M.C.6
-
19
-
-
0025801573
-
A frequent thrombomodulin amino acid dimorphism is not associated with thrombophilia
-
van der Velden PA, Krommenhoek-Van Es T, Allaart CF, Bertina RM, Reitsma PH. A frequent thrombomodulin amino acid dimorphism is not associated with thrombophilia. Thromb Haemost. 1991;65:511-513.
-
(1991)
Thromb Haemost
, vol.65
, pp. 511-513
-
-
Van Der Velden, P.A.1
Krommenhoek-Van Es, T.2
Allaart, C.F.3
Bertina, R.M.4
Reitsma, P.H.5
-
20
-
-
0028954459
-
The first mutation identified in the thrombomodulin gene in a 45-year-old man presenting with thromboembolic disease
-
Ohlin AK, Marlar RA. The first mutation identified in the thrombomodulin gene in a 45-year-old man presenting with thromboembolic disease. Blood. 1995;85:330-336.
-
(1995)
Blood
, vol.85
, pp. 330-336
-
-
Ohlin, A.K.1
Marlar, R.A.2
-
21
-
-
84879113871
-
The c1418t polymorphism in the thrombomodulin gene is associated with increased levels of circulating activated protein c
-
Medina P, España F, Villa P, Vayá A, Mira Y, Estellés A, Royo M, Bertina RM, Aznar J. The C1418T polymorphism in the thrombomodulin gene is associated with increased levels of circulating activated protein C. J Thromb Haemost. 2005;3:P1328.
-
(2005)
J Thromb Haemost
, vol.3
, pp. 1328
-
-
Medina, P.1
España, F.2
Villa, P.3
Vayá, A.4
Mira, Y.5
Estellés, A.6
Royo, M.7
Bertina, R.M.8
Aznar, J.9
-
22
-
-
0141595888
-
Prospective study of the a455v polymorphism in the thrombomodulin gene, plasma thrombomodulin, and incidence of venous thromboembolism: The lite study
-
Aleksic N, Folsom AR, Cushman M, Heckbert SR, Tsai MY, Wu KK. Prospective study of the A455V polymorphism in the thrombomodulin gene, plasma thrombomodulin, and incidence of venous thromboembolism: the LITE Study. J Thromb Haemost. 2003;1:88-94.
-
(2003)
J Thromb Haemost
, vol.1
, pp. 88-94
-
-
Aleksic, N.1
Folsom, A.R.2
Cushman, M.3
Heckbert, S.R.4
Tsai, M.Y.5
Wu, K.K.6
-
23
-
-
23044457444
-
Thrombomodulin gene polymorphisms or haplotypes as potential risk factors for venous thromboembolism: A population-based case-control study
-
Heit JA, Petterson TM, Owen WG, Burke JP, DE Andrade M, Melton LJ 3rd. Thrombomodulin gene polymorphisms or haplotypes as potential risk factors for venous thromboembolism: a population-based case-control study. J Thromb Haemost. 2005;3:710-717.
-
(2005)
J Thromb Haemost
, vol.3
, pp. 710-717
-
-
Heit, J.A.1
Petterson, T.M.2
Owen, W.G.3
Burke, J.P.D.E.4
Andrade, M.5
Melton III, L.J.6
-
24
-
-
0030855091
-
Thrombomodulin gene mutations associated with myocardial infarction
-
Ireland H, Kunz G, Kyriakoulis K, Stubbs PJ, Lane DA. Thrombomodulin gene mutations associated with myocardial infarction. Circulation. 1997;96:15-18.
-
(1997)
Circulation
, vol.96
, pp. 15-18
-
-
Ireland, H.1
Kunz, G.2
Kyriakoulis, K.3
Stubbs, P.J.4
Lane, D.A.5
-
25
-
-
0031056791
-
A common thrombomodulin amino acid dimorphism is associated with myocardial infarction
-
Norlund L, Holm J, Zöller B, Ohlin AK. A common thrombomodulin amino acid dimorphism is associated with myocardial infarction. Thromb Haemost. 1997;77:248-251.
-
(1997)
Thromb Haemost
, vol.77
, pp. 248-251
-
-
Norlund, L.1
Holm, J.2
Zöller, B.3
Ohlin, A.K.4
-
26
-
-
0035853133
-
Atherosclerosis risk in communities study (aric) investigators. Thrombomodulin ala455val polymorphism and risk of coronary heart disease
-
Wu KK, Aleksic N, Ahn C, Boerwinkle E, Folsom AR, Juneja H; Atherosclerosis Risk in Communities Study (ARIC) Investigators. Thrombomodulin Ala455Val polymorphism and risk of coronary heart disease. Circulation. 2001;103:1386-1389.
-
(2001)
Circulation
, vol.103
, pp. 1386-1389
-
-
Wu, K.K.1
Aleksic, N.2
Ahn, C.3
Boerwinkle, E.4
Folsom, A.R.5
Juneja, H.6
-
27
-
-
5444221341
-
A combination of two common thrombomodulin gene variants (-1208-1209ttdeltt and a455v) influence risk of coronary heart disease: A prospective study in men
-
Konstantoulas CJ, Cooper J, Warnock G, Miller GJ, Humphries SE, Ireland H. A combination of two common thrombomodulin gene variants (-1208-1209TTdelTT and A455V) influence risk of coronary heart disease: a prospective study in men. Atherosclerosis. 2004;177: 97-104.
-
(2004)
Atherosclerosis
, vol.177
, pp. 97-104
-
-
Konstantoulas, C.J.1
Cooper, J.2
Warnock, G.3
Miller, G.J.4
Humphries, S.E.5
Ireland, H.6
-
28
-
-
0027322651
-
Plasma thrombomodulin concentrations in relation to cardiovascular risk factors in a population sample
-
Nilsson TK, Hellsten G, Amiral J. Plasma thrombomodulin concentrations in relation to cardiovascular risk factors in a population sample. Blood Coagul Fibrinolysis. 1993;4:455-458.
-
(1993)
Blood Coagul Fibrinolysis
, vol.4
, pp. 455-458
-
-
Nilsson, T.K.1
Hellsten, G.2
Amiral, J.3
-
29
-
-
0035655929
-
Low level of circulating activated protein c is a risk factor for venous thromboembolism
-
España F, Vayá A, Mira Y, Medina P, Estellés A, Villa P, Falcó C, Aznar J. Low level of circulating activated protein C is a risk factor for venous thromboembolism. Thromb Haemost. 2001;86:1368-1373.
-
(2001)
Thromb Haemost
, vol.86
, pp. 1368-1373
-
-
España, F.1
Vayá, A.2
Mira, Y.3
Medina, P.4
Estellés, A.5
Villa, P.6
Falcó, C.7
Aznar, J.8
-
30
-
-
33644859098
-
The ser219->gly dimorphism of the endothelial protein c receptor contributes to the higher soluble protein levels observed in individuals with the a3 haplotype
-
Qu D, Wang Y, Song Y, Esmon NL, Esmon CT. The Ser219->Gly dimorphism of the endothelial protein C receptor contributes to the higher soluble protein levels observed in individuals with the A3 haplotype. J Thromb Haemost. 2006;4:229-235.
-
(2006)
J Thromb Haemost
, vol.4
, pp. 229-235
-
-
Qu, D.1
Wang, Y.2
Song, Y.3
Esmon, N.L.4
Esmon, C.T.5
-
31
-
-
50849093562
-
Endothelial protein c receptor polymorphisms and risk of myocardial infarction
-
RECAVA Thrombosis Groups
-
Medina P, Navarro S, Corral J, Zorio E, Roldán V, Estellés A, Santamaría A, Marín F, Rueda J, Bertina RM, España F; RECAVA Thrombosis Groups. Endothelial protein C receptor polymorphisms and risk of myocardial infarction. Haematologica. 2008;93: 1358-1363.
-
(2008)
Haematologica
, vol.93
, pp. 1358-1363
-
-
Medina, P.1
Navarro, S.2
Corral, J.3
Zorio, E.4
Roldán, V.5
Estellés, A.6
Santamaría, A.7
Marín, F.8
Rueda, J.9
Bertina, R.M.10
España, F.11
-
32
-
-
33750827380
-
Haplotype of thrombomodulin gene associated with plasma thrombomodulin level and deep vein thrombosis in the japanese population
-
Sugiyama S, Hirota H, Kimura R, Kokubo Y, Kawasaki T, Suehisa E, Okayama A, Tomoike H, Hayashi T, Nishigami K, Kawase I, Miyata T. Haplotype of thrombomodulin gene associated with plasma thrombomodulin level and deep vein thrombosis in the Japanese population. Thromb Res. 2007;119:35-43.
-
(2007)
Thromb Res
, vol.119
, pp. 35-43
-
-
Sugiyama, S.1
Hirota, H.2
Kimura, R.3
Kokubo, Y.4
Kawasaki, T.5
Suehisa, E.6
Okayama, A.7
Tomoike, H.8
Hayashi, T.9
Nishigami, K.10
Kawase, I.11
Miyata, T.12
-
33
-
-
0033452690
-
Analysis of thrombomodulin gene polymorphism in women with severe early-onset preeclampsia
-
Nakabayashi M, Yamamoto S, Suzuki K. Analysis of thrombomodulin gene polymorphism in women with severe early-onset preeclampsia. Semin Thromb Hemost. 1999;25:473-479.
-
(1999)
Semin Thromb Hemost
, vol.25
, pp. 473-479
-
-
Nakabayashi, M.1
Yamamoto, S.2
Suzuki, K.3
-
34
-
-
0028211896
-
Purification and characterization of two forms of soluble thrombomodulin from human urine
-
Jackson DE, Tetaz TJ, Salem HH, Mitchell CA. Purification and characterization of two forms of soluble thrombomodulin from human urine. Eur J Biochem. 1994;221:1079-1087.
-
(1994)
Eur J Biochem
, vol.221
, pp. 1079-1087
-
-
Jackson, D.E.1
Tetaz, T.J.2
Salem, H.H.3
Mitchell, C.A.4
-
35
-
-
33646683042
-
Thrombomodulin gene polymorphisms and haplotypes and the risk of cardiovascular events: A prospective follow-up study
-
Auro K, Komulainen K, Alanne M, Silander K, Peltonen L, Perola M, Salomaa V. Thrombomodulin gene polymorphisms and haplotypes and the risk of cardiovascular events: a prospective follow-up study. Arterioscler Thromb Vasc Biol. 2006;26:942-947.
-
(2006)
Arterioscler Thromb Vasc Biol
, vol.26
, pp. 942-947
-
-
Auro, K.1
Komulainen, K.2
Alanne, M.3
Silander, K.4
Peltonen, L.5
Perola, M.6
Salomaa, V.7
-
36
-
-
36249018383
-
Venous thromboembolism in carriers of the factor v leiden mutation and in patients without known thrombophilic risk factor; prediction of recurrence and apc-pci complex concentration and/or soluble thrombomodulin antigen and activity
-
Strandberg K, Svensson PJ, Ohlin AK. Venous thromboembolism in carriers of the Factor V Leiden mutation and in patients without known thrombophilic risk factor; prediction of recurrence and APC-PCI complex concentration and/or soluble thrombomodulin antigen and activity. Thromb Res. 2007;121:145-151.
-
(2007)
Thromb Res
, vol.121
, pp. 145-151
-
-
Strandberg, K.1
Svensson, P.J.2
Ohlin, A.K.3
|