Interleukin-6-signal transducer and activator of transcription-3 signaling mediates aortic dissections induced by angiotensin ii via the t-helper lymphocyte 17-interleukin 17 axis in C57BL/6 mice

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 33, Issue 7, 2013, Pages 1612-1621

  Ju, Xiaoxi ^a   Ijaz, Talha ^a   Sun, Hong ^b   Ray, Sutapa ^b,c   Lejeune, Wanda ^b   Lee, Chang ^b   Recinos III, Adrian ^b   Guo, Dong Chuan ^d   Milewicz, Dianna M ^d   Tilton, Ronald G ^b,c,e   Brasier, Allan R ^a,b,c,e  

^a Department of Biochemistry and Molecular Biology ^*  (United States)

^b University of Texas Medical Branch School of Medicine   (United States)

^c Sealy Center for Molecular Medicine   (United States)

^d UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

^e UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

Angiotensin II; Aortic dissection; Familial; Helper; Inflammation; Interleukin 6; T lymphocytes; Vascular inflammation

Indexed keywords

ANGIOTENSIN II; INTERLEUKIN 17; INTERLEUKIN 17 ANTIBODY; INTERLEUKIN 6; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; STAT3 PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; AORTA DISSECTION; ARTICLE; BLOOD PRESSURE; C57BL 6 MOUSE; CELL ACTIVATION; CELL POPULATION; ENZYME SYNTHESIS; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TH17 CELL;

ANGIOTENSIN II; AORTIC DISSECTION, FAMILIAL; INFLAMMATION; INTERLEUKIN-6; T-LYMPHOCYTES, HELPER; VASCULAR INFLAMMATION;

ANEURYSM, DISSECTING; ANGIOTENSIN II; ANIMALS; ANTIBODIES, NEUTRALIZING; AORTA; AORTIC ANEURYSM; BLOOD PRESSURE; CHEMOKINE CCL2; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; HUMANS; INFLAMMATION MEDIATORS; INTERLEUKIN-17; INTERLEUKIN-6; LYMPHOCYTE ACTIVATION; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; RNA, MESSENGER; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; TH17 CELLS; TISSUE CULTURE TECHNIQUES;

EID: 84879074286     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.112.301049     Document Type: Article

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