Clinical and neuroimaging characteristics in neurodegenerative overlap syndrome

Neurological Sciences

Volumn 34, Issue 6, 2013, Pages 875-881

  Lim, Young Min ^a   Park, Hee Kyung ^b   Kim, Jae Seung ^a   Lee, Chong Sik ^a   Chung, Sun Ju ^a   Kim, Jimin ^a   Kim, Kwang Kuk ^a  

^a University of Ulsan College of Medicine   (South Korea)

^b Inje University   (South Korea)

Author keywords

Motor neuron disease; Neurodegenerative overlap syndrome; Parkinsonism; Positron emission tomography

Indexed keywords

FLUORINE 18; LEVODOPA; N (3 FLUOROPROPYL) 2BETA CARBON ETHOXY 3BETA (4 IODOPHENYL) NORTROPANE F 18; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CAUDATE NUCLEUS; CLINICAL FEATURE; CONTROLLED STUDY; DEMENTIA; DISEASE CLASSIFICATION; ELECTROMYOGRAPHY; FEMALE; FRONTAL LOBE; HUMAN; MAJOR CLINICAL STUDY; MALE; MESENCEPHALON; MOTOR NEURON DISEASE; NEURODEGENERATIVE OVERLAP SYNDROME; NUCLEAR MAGNETIC RESONANCE IMAGING; PARKINSONISM; POSITRON EMISSION TOMOGRAPHY; PUTAMEN; THALAMUS;

AGED; AGED, 80 AND OVER; FUNCTIONAL LATERALITY; HUMANS; LEVODOPA; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; MOTOR NEURON DISEASE; PARKINSONIAN DISORDERS; POSITRON-EMISSION TOMOGRAPHY; TREMOR; TROPANES;

EID: 84879071079     PISSN: 15901874     EISSN: 15903478     Source Type: Journal    
DOI: 10.1007/s10072-012-1139-1     Document Type: Article

References (31)

1. Uitti RJ, Berry K, Yasuhara O, Eisen A, Feldman H, McGeer PL, Calne DB (1995) Neurodegenerative 'overlap' syndrome: clinical and pathological features of Parkinson's disease, motor neuron disease, and Alzheimer's disease. Parkinsonism Relat Disord 1:21-34
2. Eisen A, Calne D (1992) Amyotrophic lateral sclerosis, Parkinson's disease and Alzheimer's disease: phylogenetic disorders of the human neocortex sharing many characteristics. Can J Neurol Sci 19:117-123
3. Imamura A, Wszolek Z, Uitti R (2007) Neurodegenerative overlap syndrome: Parkinsonism and motor neuron disorder. Mov Disord 22:151-152
4. Deapen DM, Henderson BE (1986) A case-control study of amyotrophic lateral sclerosis. Am J Epidemiol 123:790-799
5. Mulder DW, Kurland LT, Offord KP, Beard CM (1986) Familial adult motor neuron disease: amyotrophic lateral sclerosis. Neurology 36:511-517
6. Fallis BA, Hardiman O (2009) Aggregation of neurodegenerative disease in ALS kindreds. Amyotroph Lateral Scler 10:95-98
7. Williams TL, Shaw PJ, Lowe J, Bates D, Ince PG (1995) Parkinsonism in motor neuron disease: case report and literature review. Acta Neuropathol 89:275-283
8. Klos KJ, Josephs KA, Parisi JE, Dickson DW (2005) Alpha-synuclein immunohistochemistry in two cases of co-occurring idiopathic Parkinson's disease and motor neuron disease. Mov Disord 20:1515-1520
9. Brait K, Fahn S, Schwarz GA (1973) Sporadic and familial parkinsonism and motor neuron disease. Neurology 23:990-1002
10. Pinkhardt EH, Sperfeld AD, Gdynia HJ, Ludolph AC, Kassubek J (2009) The combination of dopa-responsive parkinsonian syndrome and motor neuron disease. Neurodegener Dis 6:95-101
11. Gilbert RM, Fahn S, Mitsumoto H, Rowland LP (2010) Parkinsonism and motor neuron diseases: twenty-seven patients with diverse overlap syndromes. Mov Disord 25:1868-1875
12. Park HK, Lim YM, Kim JS, Lee MC, Kim SM, Kim BJ, Kim KK (2011) Nigrostriatal dysfunction in patients with amyotrophic lateral sclerosis and parkinsonism. J Neurol Sci 301:12-13
13. Qureshi AI, Wilmot G, Dihenia B, Schneider JA, Krendel DA (1996) Motor neuron disease with parkinsonism. Arch Neurol 53:987-991
14. Desai J, Swash M (1999) Extrapyramidal involvement in amyotrophic lateral sclerosis: backward falls and retropulsion. J Neurol Neurosurg Psychiatry 67:214-216
15. Zoccolella S, Palagano G, Fraddosio A, Russo I, Ferrannini E, Serlenga L, Maggio F, Lamberti S, Iliceto G (2002) ALS-plus: 5 cases of concomitant amyotrophic lateral sclerosis and parkinsonism. Neurol Sci 23(Suppl 2):S123-S124
16. Im JH, Chung SJ, Kim JS, Lee MC (2006) Differential patterns of dopamine transporter loss in the basal ganglia of progressive supranuclear palsy and Parkinson's disease: analysis with [(123)I]IPT single photon emission computed tomography. J Neurol Sci 244:103-109
17. Antonini A, Benti R, De Notaris R, Tesei S, Zecchinelli A, Sacilotto G, Meucci N, Canesi M, Mariani C, Pezzoli G, Gerundini P (2003) 123I-Ioflupane/SPECT binding to striatal dopamine transporter (DAT) uptake in patients with Parkinson's disease, multiple system atrophy, and progressive supranuclear palsy. Neurol Sci 24:149-150
18. Hudson AJ (1981) Amyotrophic lateral sclerosis and its association with dementia, parkinsonism and other neurological disorders: a review. Brain 104:217-247
19. Shintaku M, Oyanagi K, Kaneda D (2007) Amyotrophic lateral sclerosis with dementia showing clinical parkinsonism and severe degeneration of the substantia nigra: report of an autopsy case. Neuropathology 27:295-299
20. Schmitt HP, Emser W, Heimes C (1984) Familial occurrence of amyotrophic lateral sclerosis, parkinsonism, and dementia. Ann Neurol 16:642-648
21. Hideyama T, Momose T, Shimizu J, Tsuji S, Kwak S (2006) A positron emission tomography study on the role of nigral lesions in parkinsonism in patients with amyotrophic lateral sclerosis. Arch Neurol 63:1719-1722
22. Espay AJ, Spina S, Houghton DJ, Murrell JR, de Courten-Myers GM, Ghetti B, Litvan I (2011) Rapidly progressive atypical parkinsonism associated with frontotemporal lobar degeneration and motor neuron disease. J Neurol Neurosurg Psychiatry 82:751-753
23. Appel SH (1981) A unifying hypothesis for the cause of amyotrophic lateral sclerosis, parkinsonism, and Alzheimer disease. Ann Neurol 10:499-505
24. Reynolds A, Laurie C, Mosley RL, Gendelman HE (2007) Oxidative stress and the pathogenesis of neurodegenerative disorders. Int Rev Neurobiol 82:297-325
25. Martin LJ (2010) Mitochondrial pathobiology in Parkinson's disease and amyotrophic lateral sclerosis. J Alzheimers Dis 20(Suppl 2):S335-S356
26. Glass CK, Saijo K, Winner B, Marchetto MC, Gage FH (2010) Mechanisms underlying inflammation in neurodegeneration. Cell 140:918-934
27. Snow BJ, Peppard RF, Guttman M, Okada J, Martin WR, Steele J, Eisen A, Carr G, Schoenberg B, Calne D (1990) Positron emission tomographic scanning demonstrates a presynaptic dopaminergic lesion in Lytico-Bodig. The amyotrophic lateral sclerosis-parkinsonism-dementia complex of Guam. Arch Neurol 47:870-874
28. 18F]fluorodopa studies correlate with dopamine cell counts and levels. Ann Neurol 34:324-330
29. Takahashi H, Snow BJ, Bhatt MH, Peppard R, Eisen A, Calne DB (1993) Evidence for a dopaminergic deficit in sporadic amyotrophic lateral sclerosis on positron emission scanning. Lancet 342:1016-1018
30. Przedborski S, Dhawan V, Donaldson DM, Murphy PL, McKenna-Yasek D, Mandel FS, Brown RH Jr, Eidelberg D (1996) Nigrostriatal dopaminergic function in familial amyotrophic lateral sclerosis patients with and without copper/zinc superoxide dismutase mutations. Neurology 47:1546-1551
31. Borasio GD, Linke R, Schwarz J, Schlamp V, Abel A, Mozley PD, Tatsch K (1998) Dopaminergic deficit in amyotrophic lateral sclerosis assessed with [I-123] IPT single photon emission computed tomography. J Neurol Neurosurg Psychiatry 65:263-265