Solid-state amorphization of linaprazan by mechanical milling and evidence of polymorphism

Journal of Pharmaceutical Sciences

Volumn 102, Issue 7, 2013, Pages 2214-2220

  Willart, Jean Francois ^a   Durand, Morgan ^a   Briggner, Lars Erik ^b   Marx, Anke ^b   Danède, Florence ^a   Descamps, Marc ^a  

^a UNIV LILLE   (France)

^b ASTRAZENECA R AND D   (Sweden)

Author keywords

Amorphous; Calorimetry (DSC); Glass transition; Materials science; Milling; Polymorphism; Thermodynamics; Transformation; X ray powder diffractometry

Indexed keywords

LINAPRAZAN;

AMORPHIZATION; ARTICLE; CHEMICAL REACTION; DRUG STRUCTURE; SOLID STATE; THERMODYNAMICS;

EID: 84879025084     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.23573     Document Type: Article

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