Insulin-dependent apolipoprotein B degradation is mediated by autophagy and involves class I and class III phosphatidylinositide 3-kinases

Biochemical and Biophysical Research Communications

Volumn 435, Issue 4, 2013, Pages 616-620

  Sparks, Janet D ^a   O'Dell, Colleen ^a   Chamberlain, Jeffrey M ^a   Sparks, Charles E ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

Apo B; Autophagy; Liver; PI3K; PTEN; Thapsigargin; VLDL; Vps34

Indexed keywords

3 METHYLADENINE; APOLIPOPROTEIN B; ASPARAGINE; BAFILOMYCIN A1; CLASS I PHOSPHATIDYLINOSITIDE 3 KINASE; INSULIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PHOSPHOTRANSFERASE; PROTEIN KINASE B; PROTEIN P62; UNCLASSIFIED DRUG; VERY LOW DENSITY LIPOPROTEIN;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; AUTOPHAGY; CELL STRESS; CELLULAR PARAMETERS; CONTROLLED STUDY; ENDOSPLAMIC RETICULUM STRESS; GENE OVEREXPRESSION; IN VITRO STUDY; LIPID DEGRADATION; LIPID METABOLISM; LIPOPROTEIN SECRETION; LIVER CELL; LYSOSOME DEGRADATION; MOLECULAR MECHANICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; RADIOIMMUNOASSAY; RAT; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ANIMALS; APOLIPOPROTEINS B; AUTOPHAGY; CELL LINE; HEPATOCYTES; HUMANS; INSULIN; PHOSPHATIDYLINOSITOL 3-KINASES; RATS;

RATTUS;

EID: 84878980077     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2013.05.029     Document Type: Article

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