메뉴 건너뛰기




Volumn 435, Issue 3, 2013, Pages 385-390

Picropodophyllin inhibits epithelial ovarian cancer cells in vitro and in vivo

Author keywords

Cisplatin; Insulin like growth factor 1 receptor; Ovarian carcinoma; Picropodophyllin

Indexed keywords

ANTINEOPLASTIC AGENT; CISPLATIN; PICROPODOPHYLLIN; SODIUM CHLORIDE; SOMATOMEDIN C RECEPTOR; UNCLASSIFIED DRUG;

EID: 84878964512     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2013.04.097     Document Type: Article
Times cited : (11)

References (28)
  • 1
    • 78651256832 scopus 로고    scopus 로고
    • Targeting insulin and insulin-like growth factor pathways in epithelial ovarian cancer
    • Beauchamp M.C., Yasmeen A., Knafo A., et al. Targeting insulin and insulin-like growth factor pathways in epithelial ovarian cancer. J. Oncol. 2010, 2010:257058.
    • (2010) J. Oncol. , vol.2010 , pp. 257058
    • Beauchamp, M.C.1    Yasmeen, A.2    Knafo, A.3
  • 2
    • 77958095449 scopus 로고    scopus 로고
    • New advances in ovarian cancer
    • Liu J., Matulonis U.A. New advances in ovarian cancer. Oncology 2010, 24:721-728.
    • (2010) Oncology , vol.24 , pp. 721-728
    • Liu, J.1    Matulonis, U.A.2
  • 3
    • 28944440023 scopus 로고    scopus 로고
    • Standard treatment in advanced ovarian cancer in 2005: the state of the art
    • Bookman M.A. Standard treatment in advanced ovarian cancer in 2005: the state of the art. Int. J. Gynecol. Cancer 2005, 15:212-220.
    • (2005) Int. J. Gynecol. Cancer , vol.15 , pp. 212-220
    • Bookman, M.A.1
  • 4
    • 84861725367 scopus 로고    scopus 로고
    • Potent inhibitory effect of the cyclolignan picropodophyllin (PPP) on human adrenocortical carcinoma cellsproliferation
    • Doghman M., Axelson M., Lalli E. Potent inhibitory effect of the cyclolignan picropodophyllin (PPP) on human adrenocortical carcinoma cellsproliferation. Am. J. Cancer Res. 2011, 1:356-361.
    • (2011) Am. J. Cancer Res. , vol.1 , pp. 356-361
    • Doghman, M.1    Axelson, M.2    Lalli, E.3
  • 5
    • 40849131149 scopus 로고    scopus 로고
    • Insulin-like growth factor type-I receptor-dependent phosphorylation of extracellular signal-regulated kinase 1/2 but not Akt (protein kinase B) can be induced by picropodophyllin
    • Vasilcanu R., Vasilcanu D., Sehat B., et al. Insulin-like growth factor type-I receptor-dependent phosphorylation of extracellular signal-regulated kinase 1/2 but not Akt (protein kinase B) can be induced by picropodophyllin. Mol. Pharmacol. 2008, 73:930-939.
    • (2008) Mol. Pharmacol. , vol.73 , pp. 930-939
    • Vasilcanu, R.1    Vasilcanu, D.2    Sehat, B.3
  • 6
    • 33846212284 scopus 로고    scopus 로고
    • Sorafenib blocks the RAF/MEK/ERK pathway, inhibits tumor angiogenesis, and induces tumor cell apoptosis in hepatocellular carcinoma model PLC/PRF/5
    • Liu L., Cao Y., Chen C., et al. Sorafenib blocks the RAF/MEK/ERK pathway, inhibits tumor angiogenesis, and induces tumor cell apoptosis in hepatocellular carcinoma model PLC/PRF/5. Cancer Res. 2006, 66:11851-11858.
    • (2006) Cancer Res. , vol.66 , pp. 11851-11858
    • Liu, L.1    Cao, Y.2    Chen, C.3
  • 7
    • 33644751770 scopus 로고    scopus 로고
    • The insulin-like growth factor-I receptor inhibitor picropodophyllin causes tumor regression and attenuates mechanisms involved in invasion of uveal melanoma cells
    • Girnita A., All-Ericsson C., Economou M.A., et al. The insulin-like growth factor-I receptor inhibitor picropodophyllin causes tumor regression and attenuates mechanisms involved in invasion of uveal melanoma cells. Clin. Cancer Res. 2006, 12:1383-1391.
    • (2006) Clin. Cancer Res. , vol.12 , pp. 1383-1391
    • Girnita, A.1    All-Ericsson, C.2    Economou, M.A.3
  • 8
    • 0036721496 scopus 로고    scopus 로고
    • Functional insulin receptors on human epithelial ovarian carcinoma cells: implications for IGF-II mitogenic signaling
    • Kalli K.R., Falowo O.I., Bale L.K., et al. Functional insulin receptors on human epithelial ovarian carcinoma cells: implications for IGF-II mitogenic signaling. Endocrinology 2002, 143:3259-3267.
    • (2002) Endocrinology , vol.143 , pp. 3259-3267
    • Kalli, K.R.1    Falowo, O.I.2    Bale, L.K.3
  • 9
    • 30444433597 scopus 로고    scopus 로고
    • Insulin-like growth factor receptor I targeting in epithelial ovarian cancer
    • Gotlieb W.H., Bruchim I., Gu J., et al. Insulin-like growth factor receptor I targeting in epithelial ovarian cancer. Gynecol. Oncol. 2006, 100:389-396.
    • (2006) Gynecol. Oncol. , vol.100 , pp. 389-396
    • Gotlieb, W.H.1    Bruchim, I.2    Gu, J.3
  • 10
    • 60549108365 scopus 로고    scopus 로고
    • Igf1r as a therapeutic target in a mouse model of basal-like breast cancer
    • Klinakis A., Szabolcs M., Chen G., et al. Igf1r as a therapeutic target in a mouse model of basal-like breast cancer. Proc. Natl. Acad. Sci. USA 2009, 106:2359-2364.
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 2359-2364
    • Klinakis, A.1    Szabolcs, M.2    Chen, G.3
  • 12
    • 34347210331 scopus 로고    scopus 로고
    • Activation of a novel calcineurin-mediated insulin-like growth factor-1 receptor pathway, altered metabolism, and tumor cell invasion in cells subjected to mitochondrial respiratory stress
    • Guha M., Srinivasan S., Biswas G., et al. Activation of a novel calcineurin-mediated insulin-like growth factor-1 receptor pathway, altered metabolism, and tumor cell invasion in cells subjected to mitochondrial respiratory stress. J. Biol. Chem. 2007, 282:14536-14546.
    • (2007) J. Biol. Chem. , vol.282 , pp. 14536-14546
    • Guha, M.1    Srinivasan, S.2    Biswas, G.3
  • 14
    • 4544384011 scopus 로고    scopus 로고
    • Insulin-like growth factor 1 stimulates KCl cotransport, which is necessary for invasion and proliferation of cervical cancer and ovarian cancer cells
    • Shen M.R., Lin A.C., Hsu Y.M., et al. Insulin-like growth factor 1 stimulates KCl cotransport, which is necessary for invasion and proliferation of cervical cancer and ovarian cancer cells. J. Biol. Chem. 2004, 279:40017-40025.
    • (2004) J. Biol. Chem. , vol.279 , pp. 40017-40025
    • Shen, M.R.1    Lin, A.C.2    Hsu, Y.M.3
  • 15
    • 34249745222 scopus 로고    scopus 로고
    • Insulin-like growth factor-I induces cyclooxygenase-2 expression via PI3K, MAPK and PKC signaling pathways in human ovarian cancer cells
    • Cao Z., Liu L.Z., Dixon D.A., et al. Insulin-like growth factor-I induces cyclooxygenase-2 expression via PI3K, MAPK and PKC signaling pathways in human ovarian cancer cells. Cell. Signal. 2007, 19:1542-1553.
    • (2007) Cell. Signal. , vol.19 , pp. 1542-1553
    • Cao, Z.1    Liu, L.Z.2    Dixon, D.A.3
  • 16
    • 33750285711 scopus 로고    scopus 로고
    • Role of PI3K and AKT specific isoforms in ovarian cancer cell migration, invasion and proliferation through the p70S6K1 pathway
    • Meng Q., Xia C., Fang J., et al. Role of PI3K and AKT specific isoforms in ovarian cancer cell migration, invasion and proliferation through the p70S6K1 pathway. Cell Signal. 2006, 18:2262-2271.
    • (2006) Cell Signal. , vol.18 , pp. 2262-2271
    • Meng, Q.1    Xia, C.2    Fang, J.3
  • 17
    • 0242594016 scopus 로고    scopus 로고
    • The IGF-1 receptor in cancer biology
    • Baserga R., Peruzzi F., Reiss K. The IGF-1 receptor in cancer biology. Int. J. Cancer 2003, 107:873-877.
    • (2003) Int. J. Cancer , vol.107 , pp. 873-877
    • Baserga, R.1    Peruzzi, F.2    Reiss, K.3
  • 18
    • 0042889104 scopus 로고    scopus 로고
    • Expression and distribution of insulin-like growth factor-1 receptor in human carcinomas
    • Ouban A., Muraca P., Yeatman T., et al. Expression and distribution of insulin-like growth factor-1 receptor in human carcinomas. Hum. Pathol. 2003, 34:803-808.
    • (2003) Hum. Pathol. , vol.34 , pp. 803-808
    • Ouban, A.1    Muraca, P.2    Yeatman, T.3
  • 19
    • 70349751409 scopus 로고    scopus 로고
    • BMS-536924 sensitizes human epithelial ovarian cancer cells to the PARP inhibitor, 3-aminobenzamide
    • Beauchamp M.C., Knafo A., Yasmeen A., et al. BMS-536924 sensitizes human epithelial ovarian cancer cells to the PARP inhibitor, 3-aminobenzamide. Gynecol. Oncol. 2009, 115:193-198.
    • (2009) Gynecol. Oncol. , vol.115 , pp. 193-198
    • Beauchamp, M.C.1    Knafo, A.2    Yasmeen, A.3
  • 20
    • 31544464616 scopus 로고    scopus 로고
    • In vitro and in vivo antitumor effects of the dual insulin-like growth factor-I/insulin receptor inhibitor, BMS-554417
    • Haluska P., Carboni J.M., Loegering D.A., et al. In vitro and in vivo antitumor effects of the dual insulin-like growth factor-I/insulin receptor inhibitor, BMS-554417. Cancer Res. 2006, 66:362-371.
    • (2006) Cancer Res. , vol.66 , pp. 362-371
    • Haluska, P.1    Carboni, J.M.2    Loegering, D.A.3
  • 21
    • 56849114259 scopus 로고    scopus 로고
    • Oral picropodophyllin (PPP) is well tolerated in vivo and inhibits IGF-1R expression and growth of uveal melanoma
    • Economou M.A., Andersson S., Vasilcanu D., et al. Oral picropodophyllin (PPP) is well tolerated in vivo and inhibits IGF-1R expression and growth of uveal melanoma. Invest. Ophthalmol. Vis. Sci. 2008, 86:35-41.
    • (2008) Invest. Ophthalmol. Vis. Sci. , vol.86 , pp. 35-41
    • Economou, M.A.1    Andersson, S.2    Vasilcanu, D.3
  • 22
    • 30444448398 scopus 로고    scopus 로고
    • IGF-1 receptor tyrosine kinase inhibition by the cyclolignan PPP induces G2/M-phase accumulation and apoptosis in multiple myeloma cells
    • Strömberg T., Ekman S., Girnita L., et al. IGF-1 receptor tyrosine kinase inhibition by the cyclolignan PPP induces G2/M-phase accumulation and apoptosis in multiple myeloma cells. Blood 2006, 107:669-678.
    • (2006) Blood , vol.107 , pp. 669-678
    • Strömberg, T.1    Ekman, S.2    Girnita, L.3
  • 23
    • 63449104490 scopus 로고    scopus 로고
    • Inhibition of the insulin-like growth factor 1 receptor pathway enhances the antitumor effect of cisplatin in human malignant mesothelioma cell lines
    • Kai K., D'Costa S., Sills R.C., et al. Inhibition of the insulin-like growth factor 1 receptor pathway enhances the antitumor effect of cisplatin in human malignant mesothelioma cell lines. Cancer Lett. 2009, 278:49-55.
    • (2009) Cancer Lett. , vol.278 , pp. 49-55
    • Kai, K.1    D'Costa, S.2    Sills, R.C.3
  • 24
    • 66149092327 scopus 로고    scopus 로고
    • Hyperactivation of the insulin-like growth factor receptor I signaling pathway is an essential event for cisplatin resistance of ovarian cancer cells
    • Eckstein N., Servan K., Hildebrandt B., et al. Hyperactivation of the insulin-like growth factor receptor I signaling pathway is an essential event for cisplatin resistance of ovarian cancer cells. Cancer Res. 2009, 69:2996-3003.
    • (2009) Cancer Res. , vol.69 , pp. 2996-3003
    • Eckstein, N.1    Servan, K.2    Hildebrandt, B.3
  • 25
    • 79954624503 scopus 로고    scopus 로고
    • Therapeutic implications of the emerging molecular biology of uveal melanoma
    • Patel M., Smyth E., Chapman P.B., et al. Therapeutic implications of the emerging molecular biology of uveal melanoma. Clin. Cancer Res. 2011, 17:2087-2100.
    • (2011) Clin. Cancer Res. , vol.17 , pp. 2087-2100
    • Patel, M.1    Smyth, E.2    Chapman, P.B.3
  • 26
    • 70449645189 scopus 로고    scopus 로고
    • Cisplatin ototoxicity and protection: clinical and experimental studie
    • Rybak L.P., Mukherjea D., Jajoo S., et al. Cisplatin ototoxicity and protection: clinical and experimental studie. Tohoku J. Exp. Med. 2009, 219:177-186.
    • (2009) Tohoku J. Exp. Med. , vol.219 , pp. 177-186
    • Rybak, L.P.1    Mukherjea, D.2    Jajoo, S.3
  • 27
    • 70449715208 scopus 로고    scopus 로고
    • Cisplatin overdose: toxicities and management
    • Tsang R.Y., Al-Fayea T., Au H.J. Cisplatin overdose: toxicities and management. Drug Saf. 2009, 32:1109-1122.
    • (2009) Drug Saf. , vol.32 , pp. 1109-1122
    • Tsang, R.Y.1    Al-Fayea, T.2    Au, H.J.3
  • 28
    • 1642494838 scopus 로고    scopus 로고
    • Cyclolignans as inhibitors of the insulin-like growth factor-1 receptor and malignant cell growth
    • Girnita A., Girnita L., del Prete F., et al. Cyclolignans as inhibitors of the insulin-like growth factor-1 receptor and malignant cell growth. Cancer Res. 2004, 64:236-242.
    • (2004) Cancer Res. , vol.64 , pp. 236-242
    • Girnita, A.1    Girnita, L.2    del Prete, F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.