-
1
-
-
78651256832
-
Targeting insulin and insulin-like growth factor pathways in epithelial ovarian cancer
-
Beauchamp M.C., Yasmeen A., Knafo A., et al. Targeting insulin and insulin-like growth factor pathways in epithelial ovarian cancer. J. Oncol. 2010, 2010:257058.
-
(2010)
J. Oncol.
, vol.2010
, pp. 257058
-
-
Beauchamp, M.C.1
Yasmeen, A.2
Knafo, A.3
-
2
-
-
77958095449
-
New advances in ovarian cancer
-
Liu J., Matulonis U.A. New advances in ovarian cancer. Oncology 2010, 24:721-728.
-
(2010)
Oncology
, vol.24
, pp. 721-728
-
-
Liu, J.1
Matulonis, U.A.2
-
3
-
-
28944440023
-
Standard treatment in advanced ovarian cancer in 2005: the state of the art
-
Bookman M.A. Standard treatment in advanced ovarian cancer in 2005: the state of the art. Int. J. Gynecol. Cancer 2005, 15:212-220.
-
(2005)
Int. J. Gynecol. Cancer
, vol.15
, pp. 212-220
-
-
Bookman, M.A.1
-
4
-
-
84861725367
-
Potent inhibitory effect of the cyclolignan picropodophyllin (PPP) on human adrenocortical carcinoma cellsproliferation
-
Doghman M., Axelson M., Lalli E. Potent inhibitory effect of the cyclolignan picropodophyllin (PPP) on human adrenocortical carcinoma cellsproliferation. Am. J. Cancer Res. 2011, 1:356-361.
-
(2011)
Am. J. Cancer Res.
, vol.1
, pp. 356-361
-
-
Doghman, M.1
Axelson, M.2
Lalli, E.3
-
5
-
-
40849131149
-
Insulin-like growth factor type-I receptor-dependent phosphorylation of extracellular signal-regulated kinase 1/2 but not Akt (protein kinase B) can be induced by picropodophyllin
-
Vasilcanu R., Vasilcanu D., Sehat B., et al. Insulin-like growth factor type-I receptor-dependent phosphorylation of extracellular signal-regulated kinase 1/2 but not Akt (protein kinase B) can be induced by picropodophyllin. Mol. Pharmacol. 2008, 73:930-939.
-
(2008)
Mol. Pharmacol.
, vol.73
, pp. 930-939
-
-
Vasilcanu, R.1
Vasilcanu, D.2
Sehat, B.3
-
6
-
-
33846212284
-
Sorafenib blocks the RAF/MEK/ERK pathway, inhibits tumor angiogenesis, and induces tumor cell apoptosis in hepatocellular carcinoma model PLC/PRF/5
-
Liu L., Cao Y., Chen C., et al. Sorafenib blocks the RAF/MEK/ERK pathway, inhibits tumor angiogenesis, and induces tumor cell apoptosis in hepatocellular carcinoma model PLC/PRF/5. Cancer Res. 2006, 66:11851-11858.
-
(2006)
Cancer Res.
, vol.66
, pp. 11851-11858
-
-
Liu, L.1
Cao, Y.2
Chen, C.3
-
7
-
-
33644751770
-
The insulin-like growth factor-I receptor inhibitor picropodophyllin causes tumor regression and attenuates mechanisms involved in invasion of uveal melanoma cells
-
Girnita A., All-Ericsson C., Economou M.A., et al. The insulin-like growth factor-I receptor inhibitor picropodophyllin causes tumor regression and attenuates mechanisms involved in invasion of uveal melanoma cells. Clin. Cancer Res. 2006, 12:1383-1391.
-
(2006)
Clin. Cancer Res.
, vol.12
, pp. 1383-1391
-
-
Girnita, A.1
All-Ericsson, C.2
Economou, M.A.3
-
8
-
-
0036721496
-
Functional insulin receptors on human epithelial ovarian carcinoma cells: implications for IGF-II mitogenic signaling
-
Kalli K.R., Falowo O.I., Bale L.K., et al. Functional insulin receptors on human epithelial ovarian carcinoma cells: implications for IGF-II mitogenic signaling. Endocrinology 2002, 143:3259-3267.
-
(2002)
Endocrinology
, vol.143
, pp. 3259-3267
-
-
Kalli, K.R.1
Falowo, O.I.2
Bale, L.K.3
-
9
-
-
30444433597
-
Insulin-like growth factor receptor I targeting in epithelial ovarian cancer
-
Gotlieb W.H., Bruchim I., Gu J., et al. Insulin-like growth factor receptor I targeting in epithelial ovarian cancer. Gynecol. Oncol. 2006, 100:389-396.
-
(2006)
Gynecol. Oncol.
, vol.100
, pp. 389-396
-
-
Gotlieb, W.H.1
Bruchim, I.2
Gu, J.3
-
10
-
-
60549108365
-
Igf1r as a therapeutic target in a mouse model of basal-like breast cancer
-
Klinakis A., Szabolcs M., Chen G., et al. Igf1r as a therapeutic target in a mouse model of basal-like breast cancer. Proc. Natl. Acad. Sci. USA 2009, 106:2359-2364.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 2359-2364
-
-
Klinakis, A.1
Szabolcs, M.2
Chen, G.3
-
12
-
-
34347210331
-
Activation of a novel calcineurin-mediated insulin-like growth factor-1 receptor pathway, altered metabolism, and tumor cell invasion in cells subjected to mitochondrial respiratory stress
-
Guha M., Srinivasan S., Biswas G., et al. Activation of a novel calcineurin-mediated insulin-like growth factor-1 receptor pathway, altered metabolism, and tumor cell invasion in cells subjected to mitochondrial respiratory stress. J. Biol. Chem. 2007, 282:14536-14546.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 14536-14546
-
-
Guha, M.1
Srinivasan, S.2
Biswas, G.3
-
14
-
-
4544384011
-
Insulin-like growth factor 1 stimulates KCl cotransport, which is necessary for invasion and proliferation of cervical cancer and ovarian cancer cells
-
Shen M.R., Lin A.C., Hsu Y.M., et al. Insulin-like growth factor 1 stimulates KCl cotransport, which is necessary for invasion and proliferation of cervical cancer and ovarian cancer cells. J. Biol. Chem. 2004, 279:40017-40025.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 40017-40025
-
-
Shen, M.R.1
Lin, A.C.2
Hsu, Y.M.3
-
15
-
-
34249745222
-
Insulin-like growth factor-I induces cyclooxygenase-2 expression via PI3K, MAPK and PKC signaling pathways in human ovarian cancer cells
-
Cao Z., Liu L.Z., Dixon D.A., et al. Insulin-like growth factor-I induces cyclooxygenase-2 expression via PI3K, MAPK and PKC signaling pathways in human ovarian cancer cells. Cell. Signal. 2007, 19:1542-1553.
-
(2007)
Cell. Signal.
, vol.19
, pp. 1542-1553
-
-
Cao, Z.1
Liu, L.Z.2
Dixon, D.A.3
-
16
-
-
33750285711
-
Role of PI3K and AKT specific isoforms in ovarian cancer cell migration, invasion and proliferation through the p70S6K1 pathway
-
Meng Q., Xia C., Fang J., et al. Role of PI3K and AKT specific isoforms in ovarian cancer cell migration, invasion and proliferation through the p70S6K1 pathway. Cell Signal. 2006, 18:2262-2271.
-
(2006)
Cell Signal.
, vol.18
, pp. 2262-2271
-
-
Meng, Q.1
Xia, C.2
Fang, J.3
-
18
-
-
0042889104
-
Expression and distribution of insulin-like growth factor-1 receptor in human carcinomas
-
Ouban A., Muraca P., Yeatman T., et al. Expression and distribution of insulin-like growth factor-1 receptor in human carcinomas. Hum. Pathol. 2003, 34:803-808.
-
(2003)
Hum. Pathol.
, vol.34
, pp. 803-808
-
-
Ouban, A.1
Muraca, P.2
Yeatman, T.3
-
19
-
-
70349751409
-
BMS-536924 sensitizes human epithelial ovarian cancer cells to the PARP inhibitor, 3-aminobenzamide
-
Beauchamp M.C., Knafo A., Yasmeen A., et al. BMS-536924 sensitizes human epithelial ovarian cancer cells to the PARP inhibitor, 3-aminobenzamide. Gynecol. Oncol. 2009, 115:193-198.
-
(2009)
Gynecol. Oncol.
, vol.115
, pp. 193-198
-
-
Beauchamp, M.C.1
Knafo, A.2
Yasmeen, A.3
-
20
-
-
31544464616
-
In vitro and in vivo antitumor effects of the dual insulin-like growth factor-I/insulin receptor inhibitor, BMS-554417
-
Haluska P., Carboni J.M., Loegering D.A., et al. In vitro and in vivo antitumor effects of the dual insulin-like growth factor-I/insulin receptor inhibitor, BMS-554417. Cancer Res. 2006, 66:362-371.
-
(2006)
Cancer Res.
, vol.66
, pp. 362-371
-
-
Haluska, P.1
Carboni, J.M.2
Loegering, D.A.3
-
21
-
-
56849114259
-
Oral picropodophyllin (PPP) is well tolerated in vivo and inhibits IGF-1R expression and growth of uveal melanoma
-
Economou M.A., Andersson S., Vasilcanu D., et al. Oral picropodophyllin (PPP) is well tolerated in vivo and inhibits IGF-1R expression and growth of uveal melanoma. Invest. Ophthalmol. Vis. Sci. 2008, 86:35-41.
-
(2008)
Invest. Ophthalmol. Vis. Sci.
, vol.86
, pp. 35-41
-
-
Economou, M.A.1
Andersson, S.2
Vasilcanu, D.3
-
22
-
-
30444448398
-
IGF-1 receptor tyrosine kinase inhibition by the cyclolignan PPP induces G2/M-phase accumulation and apoptosis in multiple myeloma cells
-
Strömberg T., Ekman S., Girnita L., et al. IGF-1 receptor tyrosine kinase inhibition by the cyclolignan PPP induces G2/M-phase accumulation and apoptosis in multiple myeloma cells. Blood 2006, 107:669-678.
-
(2006)
Blood
, vol.107
, pp. 669-678
-
-
Strömberg, T.1
Ekman, S.2
Girnita, L.3
-
23
-
-
63449104490
-
Inhibition of the insulin-like growth factor 1 receptor pathway enhances the antitumor effect of cisplatin in human malignant mesothelioma cell lines
-
Kai K., D'Costa S., Sills R.C., et al. Inhibition of the insulin-like growth factor 1 receptor pathway enhances the antitumor effect of cisplatin in human malignant mesothelioma cell lines. Cancer Lett. 2009, 278:49-55.
-
(2009)
Cancer Lett.
, vol.278
, pp. 49-55
-
-
Kai, K.1
D'Costa, S.2
Sills, R.C.3
-
24
-
-
66149092327
-
Hyperactivation of the insulin-like growth factor receptor I signaling pathway is an essential event for cisplatin resistance of ovarian cancer cells
-
Eckstein N., Servan K., Hildebrandt B., et al. Hyperactivation of the insulin-like growth factor receptor I signaling pathway is an essential event for cisplatin resistance of ovarian cancer cells. Cancer Res. 2009, 69:2996-3003.
-
(2009)
Cancer Res.
, vol.69
, pp. 2996-3003
-
-
Eckstein, N.1
Servan, K.2
Hildebrandt, B.3
-
25
-
-
79954624503
-
Therapeutic implications of the emerging molecular biology of uveal melanoma
-
Patel M., Smyth E., Chapman P.B., et al. Therapeutic implications of the emerging molecular biology of uveal melanoma. Clin. Cancer Res. 2011, 17:2087-2100.
-
(2011)
Clin. Cancer Res.
, vol.17
, pp. 2087-2100
-
-
Patel, M.1
Smyth, E.2
Chapman, P.B.3
-
26
-
-
70449645189
-
Cisplatin ototoxicity and protection: clinical and experimental studie
-
Rybak L.P., Mukherjea D., Jajoo S., et al. Cisplatin ototoxicity and protection: clinical and experimental studie. Tohoku J. Exp. Med. 2009, 219:177-186.
-
(2009)
Tohoku J. Exp. Med.
, vol.219
, pp. 177-186
-
-
Rybak, L.P.1
Mukherjea, D.2
Jajoo, S.3
-
27
-
-
70449715208
-
Cisplatin overdose: toxicities and management
-
Tsang R.Y., Al-Fayea T., Au H.J. Cisplatin overdose: toxicities and management. Drug Saf. 2009, 32:1109-1122.
-
(2009)
Drug Saf.
, vol.32
, pp. 1109-1122
-
-
Tsang, R.Y.1
Al-Fayea, T.2
Au, H.J.3
-
28
-
-
1642494838
-
Cyclolignans as inhibitors of the insulin-like growth factor-1 receptor and malignant cell growth
-
Girnita A., Girnita L., del Prete F., et al. Cyclolignans as inhibitors of the insulin-like growth factor-1 receptor and malignant cell growth. Cancer Res. 2004, 64:236-242.
-
(2004)
Cancer Res.
, vol.64
, pp. 236-242
-
-
Girnita, A.1
Girnita, L.2
del Prete, F.3
|