Reversal of the substrate specificity of CMP N-glycosidase to dCMP

Biochemistry

Volumn 52, Issue 23, 2013, Pages 4037-4047

  Sikowitz, Megan D ^a   Cooper, Lisa E ^b   Begley, Tadhg P ^b   Kaminski, Pierre Alexandre ^c   Ealick, Steven E ^a  

^a Cornell University ^*  (United States)

^b TEXAS A AND M UNIVERSITY   (United States)

^c CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE RESIDUES; ANTIFUNGAL COMPOUNDS; BIOSYNTHETIC PATHWAY; DEOXYNUCLEOSIDES; N-GLYCOSIDIC BONDS; PHENYLALANINE RESIDUES; SUBSTRATE SPECIFICITY; TYROSINE RESIDUES;

AMINO ACIDS; BIOCHEMISTRY; BIOMOLECULES; BIOSYNTHESIS; ENZYMES;

SUBSTRATES;

BCMB PROTEIN; CYTIDINE PHOSPHATE; DEOXYCYTIDINE PHOSPHATE; GLYCOSIDASE; HYDROXYL GROUP; MILB PROTEIN; NUCLEIC ACID BASE; NUCLEOSIDE; PHENYLALANINE; TYROSINE; UNCLASSIFIED DRUG;

ARTICLE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SYNTHESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

AMINO ACID SUBSTITUTION; BACTERIAL PROTEINS; CATALYTIC DOMAIN; CLOSTRIDIUM BOTULINUM TYPE A; CRYSTALLOGRAPHY, X-RAY; DEOXYCYTIDINE MONOPHOSPHATE; KINETICS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PENTOSYLTRANSFERASES; PROTEIN STRUCTURE, SECONDARY; STREPTOMYCES; STRUCTURAL HOMOLOGY, PROTEIN; SUBSTRATE SPECIFICITY;

EID: 84878951875     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi400316p     Document Type: Article

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