α-Lipoic acid prevents p53 degradation in colon cancer cells by blocking NF-κB induction of RPS6KA4

Anti-Cancer Drugs

Volumn 24, Issue 6, 2013, Pages 555-565

  Yoo, Tae Hyoung ^a   Lee, Jin Hee ^a   Chun, Hyang Sook ^b   Chi, Sung Gil ^a  

^a Korea University   (South Korea)

^b Chung Ang University   (South Korea)

Author keywords

Lipoic acid; apoptosis; colon cancer; p53; RPS6KA4

Indexed keywords

3 (4 METHYLPHENYLSULFONYL) 2 PROPENENITRILE; ETOPOSIDE; FLUOROURACIL; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN P53; RIBOSOMAL PROTEIN P90S6K; RIBOSOME PROTEIN; THIOCTIC ACID; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL STRAIN HCT116; CONTROLLED STUDY; DOSE RESPONSE; DOWN REGULATION; DRUG EFFECT; DRUG MECHANISM; G1 PHASE CELL CYCLE CHECKPOINT; GAMMA IRRADIATION; HUMAN; HUMAN CELL; HYPOXIA; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN STABILITY; REGULATORY MECHANISM; ULTRAVIOLET C RADIATION;

ANOXIA; ANTINEOPLASTIC AGENTS; ANTIOXIDANTS; APOPTOSIS; DOSE-RESPONSE RELATIONSHIP, DRUG; G1 PHASE CELL CYCLE CHECKPOINTS; HCT116 CELLS; HUMANS; NF-KAPPA B; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RIBOSOMAL PROTEIN S6 KINASES, 90-KDA; THIOCTIC ACID; TUMOR NECROSIS FACTOR-ALPHA; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84878951705     PISSN: 09594973     EISSN: 14735741     Source Type: Journal    
DOI: 10.1097/CAD.0b013e32836181eb     Document Type: Article

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