Transcriptional profiling and pathway analysis of CSF-1 and IL-34 effects on human monocyte differentiation

Cytokine

Volumn 63, Issue 1, 2013, Pages 10-17

  Barve, Ruteja A ^a   Zack, Marc D ^a   Weiss, David ^a   Song, Ruo Hua ^a   Beidler, David ^a   Head, Richard D ^a  

^a PFIZER INC   (United States)

Author keywords

CSF 1; Differentiation; IL 34; Macrophage; Monocyte

Indexed keywords

CD14 ANTIGEN; CHEMOKINE RECEPTOR CCR2; COLONY STIMULATING FACTOR 1; COLONY STIMULATING FACTOR 1 RECEPTOR; COLONY STIMULATING FACTOR RECEPTOR; CYTOKINE; INTERLEUKIN 34; UNCLASSIFIED DRUG;

ARTICLE; CELL DIFFERENTIATION; COMPLEMENT SYSTEM; CONTROLLED STUDY; FLOW CYTOMETRY; FLUORESCENCE ACTIVATED CELL SORTING; GENE EXPRESSION PROFILING; GENETIC ASSOCIATION; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; MACROPHAGE; MICROARRAY ANALYSIS; MONOCYTE; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSCRIPTION REGULATION;

BIOLOGICAL MARKERS; CELL DIFFERENTIATION; FLOW CYTOMETRY; GENE EXPRESSION PROFILING; HUMANS; INTERLEUKINS; MACROPHAGE COLONY-STIMULATING FACTOR; MACROPHAGES; MONOCYTES; RECEPTORS, CCR2; REPRODUCIBILITY OF RESULTS; SIGNAL TRANSDUCTION; TISSUE DONORS;

EID: 84878951452     PISSN: 10434666     EISSN: 10960023     Source Type: Journal    
DOI: 10.1016/j.cyto.2013.04.019     Document Type: Article

References (35)

1. Dai X.M., Zhong X.H., Sylvestre V., Stanley E.R. Incomplete restoration of colony-stimulating factor 1 (CSF-1) function in CSF-1-deficient Csf1op/Csf1op mice by transgenic expression of cell surface CSF-1. Blood 2004, 103:1114-1123.
2. Ryan G.R., Dai X.M., Dominguez M.G., Tong W., Chuan F., Chisholm O., et al. Rescue of the colony-stimulating factor 1 (CSF-1)-nullizygous mouse (Csf1(op)/Csf1(op)) phenotype with a CSF-1 transgene and identification of sites of local CSF-1 synthesis. Blood 2001, 98:74-84.
3. Wiktor-jedrzejczak W.W., Ahmed A., Szczylik C., Skelly R.R. Hematological characterization of congenital osteopetrosis in op/op mouse. Possible mechanism for abnormal macrophage differentiation. J Exp Med 1982, 156:1516-1527.
4. Dai X.M., Ryan G.R., Hapel A.J., Dominguez M.G., Russell R.G., Kapp S., et al. Targeted disruption of the mouse colony-stimulating factor 1 receptor gene results in osteopetrosis, mononuclear phagocyte deficiency, increased primitive progenitor cell frequencies, and reproductive defects. Blood 2002, 99:111-120.
5. Begg S.K., Radley J.M., Pollard J.W., Chisholm O.T., Stanley E.R., Bertoncello I. Delayed hematopoietic development in osteopetrotic (op/op) mice. J Exp Med 1993, 177:237-242.
6. Begg S.K., Bertoncello I. The hematopoietic deficiencies in osteopetrotic (op/op) mice are not permanent, but progressively correct with age. Exp Hematol 1993, 21:493-495.
7. Burns C.J., Wilks A.F. C-FMS inhibitors: a patent review. Expert Opin Ther Pat 2011, 21:147-165.
8. Lin H., Lee E., Hestir K., Leo C., Huang M., Bosch E., et al. Discovery of a cytokine and its receptor by functional screening of the extracellular proteome. Science 2008, 320:807-811.
9. Matsumura T., Sakai M., Matsuda K., Furukawa N., Kaneko K., Shichiri M. Cis-acting DNA elements of mouse granulocyte/macrophage colony-stimulating factor gene responsive to oxidized low density lipoprotein. J Biol Chem 1999, 274.
10. Bartocci A., Pollard J.W., Stanley E.R. Regulation of colony-stimulating factor 1 during pregnancy. J Exp Med 1986, 164:956-961.
11. Chihara T., Suzu S., Hassan R., Chutiwitoonchai N., Hiyoshi M., Motoyoshi K., et al. IL-34 and M-CSF share the receptor Fms but are not identical in biological activity and signal activation. Cell death differ 2010, 17:1917-1927.
12. Chen Z., Buki K., Vääräniemi J., Gu G., Väänänen H.K. The critical role of IL-34 in osteoclastogenesis. PLos One 2011, 6:e18689.
13. Liu H., Leo C., Chen X., Wong B.R., Williams L.T., Lin H., et al. The mechanism of shared but distinct CSF-1R signaling by the non-homologous cytokines IL-34 and CSF-1. Biochim Biophys Acta 2012, 1824(7):938-945.
14. Lehtonen A., Ahlfors H., Veckman V., Miettinen M., Lahesmaa R., Julkunen I. Gene expression profiling during differentiation of human monocytes to macrophages or dendritic cells. J Leukoc Biol 2007, 82:710-720.
15. Liu H., Shi B., Huang C.-C., Eksarko P., Pope R.M. Transcriptional diversity during monocyte to macrophage differentiation. Immunol Lett 2008, 117:70-80.
16. Eda H., Shimada H., Beidler D.R., Monahan J.B. Proinflammatory cytokines, IL-1β and TNF-α, induce expression of interleukin-34 mRNA via JNK- and p44/42 MAPK-NF-κB pathway but not p38 pathway in osteoblasts. Rheumatol Int 2010, (December).
17. Livak K.J., Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001, 25:402-408.
18. Dijk K.W., Hofker M.H., Havekes L.M. Dissection of the complex role of apolipoprotein E in lipoprotein metabolism and atherosclerosis using mouse models. Curr Atheroscler Rep 1999, 1:101-107.
19. van Ree J.H., Hofker M., van den Broek W.J., van Deursen J.M., van der Boom H., Frants R.R., et al. Increased response to cholesterol feeding in apolipoprotein C1-deficient mice. Biochem J 1995, 305:905-911.
20. Kockx M., Jessup W., Kritharides L. Regulation of endogenous apolipoprotein E secretion by macrophages. Arterioscler Thromb Vasc Biol 2008, 28:1060-1067.
21. Charo I.F., Myers S., Herman A., Franci C., Connolly A.J., Coughlin S.R. Molecular cloning and functional expression of two monocyte chemoattractant protein 1 receptors reveals alternative splicing of the carboxyl-terminal tails. Proc Natl Acad Sci USA 1994, 91:2752-2756.
22. Garceau V., Smith J., Paton I.R., Davey M., Fares M.A., Sester D.P., et al. Pivotal advance: avian colony-stimulating factor 1 (CSF-1), interleukin-34 (IL-34), and CSF-1 receptor genes and gene products. J Leukoc Biol 2010, 87:753-764.
23. Martinez F.O., Gordon S., Locati M., Mantovani A. Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene expression. J Immunol 2006, 177:7303-7311.
24. Mroczko B., Groblewska M., Wereszczyńska-Siemiatkowska U., Okulczyk B., Kedra B., Łaszewicz W., et al. Serum macrophage-colony stimulating factor levels in colorectal cancer patients correlate with lymph node metastasis and poor prognosis. Clin Chim Acta 2007, 380:208-212.
25. Weinberg J.B., Haney A., Xu F.J., Ramakrishnan S. Peritoneal fluid and plasma levels of human macrophage colony-stimulating factor in relation to peritoneal fluid macrophage content. Blood 1991, 78:513-516.
26. Grasset M.-F., Gobert G.S., Mouchiroud G, Bourette R.P. Macrophage differentiation of myeloid progenitor cells in response to M-CSF is regulated by the dual-specificity phosphatase DUSP5. J Leukoc Biol 2010, 87:127-135.
27. Caunt C.J., Rivers C.A., Conway-Campbell B.L., Norman M.R., McArdle C.A. Epidermal growth factor receptor and protein kinase C signaling to ERK2: spatiotemporal regulation of ERK2 by dual specificity phosphatases. J Biol Chem 2008, 283:6241-6252.
28. Irvine K.M., Andrews M.R., Fernandez-Rojo M.A., Schroder K., Burns C.J., Su S., et al. Colony-stimulating factor-1 (CSF-1) delivers a proatherogenic signal to human macrophages. J Leukoc Biol 2009, 85:278-288.
29. Kodvawala A., Ghering A.B., Davidson W.S., Hui D.Y. Carboxyl ester lipase expression in macrophages increases cholesteryl ester accumulation and promotes atherosclerosis. J Biol Chem 2005, 280:38592-38598.
30. Yang X.P., Yan D., Qiao C., Liu R.J., Chen J.-G., Li J., et al. Increased atherosclerotic lesions in apoE mice with plasma phospholipid transfer protein overexpression. Arterioscler Thromb Vasc Biol 2003, 23:1601-1607.
31. Wechsler A., Brafman A., Shafir M., Heverin M., Gottlieb H., Damari G., et al. Cholesterol-free mice. Science 2003, 302:52621.
32. Stein Y., Stein O. Lipoprotein lipase and atherosclerosis. Atherosclerosis 2003, 170:1-9.
33. Boring L., Gosling J., Cleary M., Charo I.F. Decreased lesion formation in CCR2-/- mice reveals a role for chemokines in the initiation of atherosclerosis. Nature 1998, 394:894-897.
34. Phillips R.J., Lutz M., Premack B. Differential signaling mechanisms regulate expression of CC chemokine receptor-2 during monocyte maturation. J Inflamm (Lond) 2005, 31:2-14.
35. Wong L.M., Myers S., Tsou C.L., Gosling J., Arai H., Charo I.F. Organization and differential expression of the human monocyte chemoattractant protein 1 receptor gene. Evidence for the role of the carboxyl-terminal tail in receptor trafficking. J Biol Chem 1997, 272:1038-1045.