Cytogenetic analysis of human cells reveals specific patterns of DNA damage in replicative and oncogene-induced senescence

Aging Cell

Volumn 12, Issue 2, 2013, Pages 312-315

  Falcone, Germana ^a,b   Mazzola, Alessia ^a   Michelini, Flavia ^a   Bossi, Gianluca ^c   Censi, Federica ^a   Biferi, Maria G ^a   Minghetti, Luisa ^a   Floridia, Giovanna ^a   Federico, Maurizio ^a   Musio, Antonio ^d,e   Crescenzi, Marco ^a  

^a ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^b CNR   (Italy)

^c REGINA ELENA NATIONAL CANCER INSTITUTE   (Italy)

^d Milan Unit   (Italy)

^e ISTITUTO TOSCANO TUMORI   (Italy)

Author keywords

Cell cycle inhibitors; Cytogenetic analysis; DNA damage; Oncogene induced senescence; Replicative senescence; Telomerase

Indexed keywords

DOUBLE STRANDED DNA; HISTONE H2AX; PROTEIN P16; PROTEIN P21; SMALL INTERFERING RNA; TELOMERASE REVERSE TRANSCRIPTASE;

ANEUPLOIDY; ARTICLE; CARCINOGENESIS; CELL AGING; CELL CYCLE; CELL POPULATION; CELL PROLIFERATION; CHROMOSOME 1; CHROMOSOME ABERRATION; CHROMOSOME ANALYSIS; CHROMOSOME BREAKAGE; CHROMOSOME DAMAGE; COMPARATIVE GENOMIC HYBRIDIZATION; DNA DAMAGE; DOUBLE STRANDED DNA BREAK; FIBROBLAST; GENETIC DAMAGE; HUMAN; HUMAN CELL; MITOSIS; ONCOGENE; PRIORITY JOURNAL; PROTO ONCOGENE; TELOMERE;

CELL AGING; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYTOGENETIC ANALYSIS; DNA DAMAGE; FIBROBLASTS; GENETIC VECTORS; HUMANS; LENTIVIRUS; NEOPLASM PROTEINS; ONCOGENES; RNA, SMALL INTERFERING; TELOMERASE; TELOMERE; TRANSDUCTION, GENETIC;

EID: 84878950563     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/acel.12034     Document Type: Article

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