A Branched Biosynthetic Pathway Is Involved in Production of Roquefortine and Related Compounds in Penicillium chrysogenum

PLoS ONE

Volumn 8, Issue 6, 2013, Pages

  Ali, Hazrat ^a,b   Ries, Marco I ^c   Nijland, Jeroen G ^a,b   Lankhorst, Peter P ^d   Hankemeier, Thomas ^c,e   Bovenberg, Roel A L ^a,d   Vreeken, Rob J ^c,e   Driessen, Arnold J M ^a,b  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

^b Industrial Fermentation   (Netherlands)

^c LEIDEN UNIVERSITY   (Netherlands)

^d DSM BIOTECHNOLOGY CENTER   (Netherlands)

^e LEIDEN UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; CYTOCHROME P450 REDUCTASE; DEHYDROHISTIDYLTRYPTOPHANYLDI KETOPIPERAZINE; DIMETHYLALLYLTRYPTOPHAN SYNTHETASE; GENOMIC DNA; GLANDICOLINE A; GLANDICOLINE B; HISTIDINE; HISTIDYLTRYPTOPHANYLDIKETOPIPERAZINE; MELEAGRIN; METHYLTRANSFERASE; NONRIBOSOMAL PEPTIDE SYNTHETASE; RNA; ROQUEFORTINE; ROQUEFORTINE D; SYNTHETASE; TRYPTOPHAN; UNCLASSIFIED DRUG;

ARTICLE; BIOSYNTHESIS; DNA EXTRACTION; ENZYME MECHANISM; FUNGAL GENE; FUNGAL STRAIN; GENE AMPLIFICATION; GENE CLUSTER; GENE DELETION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MICROARRAY ANALYSIS; NONHUMAN; PENICILLIUM CHRYSOGENUM; PLASMID; REVERSED PHASE LIQUID CHROMATOGRAPHY; RNA EXTRACTION; ROQD GENE; ROQM GENE; ROQN GENE; ROQO GENE; ROQR GENE; ROQT GENE; SOUTHERN BLOTTING;

BIOSYNTHETIC PATHWAYS; BLOTTING, SOUTHERN; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DNA PRIMERS; HETEROCYCLIC COMPOUNDS WITH 4 OR MORE RINGS; INDOLES; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; MICROARRAY ANALYSIS; MULTIGENE FAMILY; OVOMUCIN; PENICILLIUM CHRYSOGENUM; PIPERAZINES; PLASMIDS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

FUNGI; PENICILLIUM CHRYSOGENUM;

EID: 84878938243     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0065328     Document Type: Article

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