Shaping T Cell - B Cell Collaboration in the Response to Human Immunodeficiency Virus Type 1 Envelope Glycoprotein gp120 by Peptide Priming

PLoS ONE

Volumn 8, Issue 6, 2013, Pages

  Steede, N Kalaya ^a   Rust, Blake J ^a   Hossain, Mohammad M ^a   Freytag, Lucy C ^a   Robinson, James E ^a   Landry, Samuel J ^a  

^a TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; EPITOPE; GLYCOPROTEIN GP 120; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN M ANTIBODY; INTERLEUKIN 2; INTERLEUKIN 5; PEPTIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY BLOOD LEVEL; ANTIBODY TITER; ARTICLE; B LYMPHOCYTE; CELLULAR IMMUNITY; CONTROLLED STUDY; CROSS REACTION; CYTOKINE PRODUCTION; CYTOKINE RELEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME LINKED IMMUNOSPOT ASSAY; FEMALE; HUMAN IMMUNODEFICIENCY VIRUS 1; IMMUNE RESPONSE; IMMUNIZATION; LYMPHOCYTE ACTIVATION; MOUSE; NONHUMAN; PEPTIDE PRIMING; PROTEIN FUNCTION; SPLEEN CELL; T LYMPHOCYTE;

ANIMALS; B-LYMPHOCYTE SUBSETS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HIV ENVELOPE PROTEIN GP120; HIV-1; HUMANS; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; INTERLEUKIN-2; MICE; MICE, INBRED BALB C; PEPTIDES; T-LYMPHOCYTE SUBSETS;

ANIMALIA; HUMAN IMMUNODEFICIENCY VIRUS 1; MUS;

EID: 84878922916     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0065748     Document Type: Article

References (47)

1. Lai L, Kwa S, Kozlowski PA, Montefiori DC, Ferrari G, et al. (2011) Prevention of Infection by a Granulocyte-Macrophage Colony-Stimulating Factor Co-Expressing DNA/Modified Vaccinia Ankara Simian Immunodeficiency Virus Vaccine. J Infect Dis 204: 164-173.
2. Haynes BF, Gilbert PB, McElrath MJ, Zolla-Pazner S, Tomaras GD, et al. (2012) Immune-correlates analysis of an HIV-1 vaccine efficacy trial. N Engl J Med 366: 1275-1286.
3. Letvin NL, Rao SS, Montefiori DC, Seaman MS, Sun Y, et al. (2011) Immune and Genetic Correlates of Vaccine Protection Against Mucosal Infection by SIV in Monkeys. Sci Transl Med 3: 81ra36.
4. Pancera M, McLellan JS, Wu X, Zhu J, Changela A, et al. (2010) Crystal structure of PG16 and chimeric dissection with somatically related PG9: structure-function analysis of two quaternary-specific antibodies that effectively neutralize HIV-1. J Virol 84: 8098-8110.
5. Wu X, Zhou T, Zhu J, Zhang B, Georgiev I, et al. (2011) Focused evolution of HIV-1 neutralizing antibodies revealed by structures and deep sequencing. Science 333: 1593-1602.
6. Bonsignori M, Alam SM, Liao HX, Verkoczy L, Tomaras GD, et al. (2012) HIV-1 antibodies from infection and vaccination: insights for guiding vaccine design. Trends Microbiol 20: 532-539.
7. Noelle RJ, Shepherd DM, Fell HP, (1992) Cognate interaction between T helper cells and B cells. VII. Role of contact and lymphokines in the expression of germ-line and mature gamma 1 transcripts. J Immunol 149: 1164-1169.
8. Reinhardt RL, Liang HE, Locksley RM, (2009) Cytokine-secreting follicular T cells shape the antibody repertoire. Nat Immunol 10: 385-393.
9. Jin H, Malek TR, (2006) Redundant and unique regulation of activated mouse B lymphocytes by IL-4 and IL-21. J Leukoc Biol 80: 1416-1423.
10. Mitsdoerffer M, Lee Y, Jager A, Kim HJ, Korn T, et al. (2010) Proinflammatory T helper type 17 cells are effective B-cell helpers. Proc Natl Acad Sci U S A 107: 14292-14297.
11. Maric M, Arunachalam B, Phan UT, Dong C, Garrett WS, et al. (2001) Defective antigen processing in GILT-free mice. Science 294: 1361-1365.
12. Li H, Xu CF, Blais S, Wan Q, Zhang HT, et al. (2009) Proximal glycans outside of the epitopes regulate the presentation of HIV-1 envelope gp120 helper epitopes. J Immunol 182: 6369-6378.
13. Mirano-Bascos D, Steede NK, Robinson JE, Landry SJ, (2010) Influence of Disulfide-Stabilized Structure on the Specificity of Helper T-Cell and Antibody Responses to HIV Envelope Glycoprotein gp120. J Virol 84: 3303-3311.
14. Dzuris JL, Sidney J, Horton H, Correa R, Carter D, et al. (2001) Molecular determinants of peptide binding to two common rhesus macaque major histocompatibility complex class II molecules. J Virol 75: 10958-10968.
15. Moon JJ, Chu HH, Pepper M, McSorley SJ, Jameson SC, et al. (2007) Naive CD4(+) T cell frequency varies for different epitopes and predicts repertoire diversity and response magnitude. Immunity 27: 203-213.
16. Choi YS, Kageyama R, Eto D, Escobar TC, Johnston RJ, et al. (2011) ICOS receptor instructs T follicular helper cell versus effector cell differentiation via induction of the transcriptional repressor Bcl6. Immunity 34: 932-946.
17. Crotty S, (2011) Follicular helper CD4 T cells (TFH). Annu Rev Immunol 29: 621-663.
18. Turcanu V, Winterbotham M, Kelleher P, Lack G, (2008) Peanut-specific B and T cell responses are correlated in peanut-allergic but not in non-allergic individuals. Clin Exp Allergy 38: 1132-1139.
19. Sette A, Moutaftsi M, Moyron-Quiroz J, McCausland MM, Davies DH, et al. (2008) Selective CD4+ T cell help for antibody responses to a large viral pathogen: deterministic linkage of specificities. Immunity 28: 847-858.
20. Nayak JL, Fitzgerald TF, Richards KA, Yang H, Treanor JJ, et al. (2013) CD4+ T-cell expansion predicts neutralizing antibody responses to monovalent, inactivated 2009 pandemic influenza A(H1N1) virus subtype H1N1 vaccine. J Infect Dis 207: 297-305.
21. Berzofsky JA, (1983) T-B reciprocity. An Ia-restricted epitope-specific circuit regulating T cell-B cell interaction and antibody specificity. Surveys of Immunology Research 2: 223.
22. Watts C, Antoniou A, Manoury B, Hewitt EW, McKay LM, et al. (1998) Modulation by epitope-specific antibodies of class II MHC-restricted presentation of the tetanus toxin antigen. Immunological Reviews 164: 11-16.
23. Gao F, Li Y, Decker JM, Peyerl FW, Bibollet-Ruche F, et al. (2003) Codon usage optimization of HIV type 1 subtype C gag, pol, env, and nef genes: in vitro expression and immune responses in DNA-vaccinated mice. AIDS Res Hum Retroviruses 19: 817-823.
24. Illick MM, Branco LM, Fair JN, Illick KA, Matschiner A, et al. (2008) Uncoupling GP1 and GP2 expression in the Lassa virus glycoprotein complex: implications for GP1 ectodomain shedding. Virol J 5: 161.
25. Dai G, Steede NK, Landry SJ, (2001) Allocation of helper T-cell epitope immunodominance according to three-dimensional structure in the human immunodeficiency virus type I envelope glycoprotein gp120. Journal of Biological Chemistry 276: 41913-41920.
26. Chong C, Friberg M, Clements JD, (1998) LT(R192G), a non-toxic mutant of the heat-labile enterotoxin of Escherichia coli, elicits enhanced humoral and cellular immune responses associated with protection against lethal oral challenge with Salmonella spp. Vaccine 16: 732-740.
27. Nutt SL, Taubenheim N, Hasbold J, Corcoran LM, Hodgkin PD, (2011) The genetic network controlling plasma cell differentiation. Semin Immunol 23: 341-349.
28. Horikawa K, Takatsu K, (2006) Interleukin-5 regulates genes involved in B-cell terminal maturation. Immunology 118: 497-508.
29. Punnonen J, de Vries JE, (1994) IL-13 induces proliferation, Ig isotype switching, and Ig synthesis by immature human fetal B cells. J Immunol 152: 1094-1102.
30. Ma CS, Deenick EK, Batten M, Tangye SG, (2012) The origins, function, and regulation of T follicular helper cells. J Exp Med 209: 1241-1253.
31. Lang KS, Hegazy AN, Lang PA, Eschli B, Lohning M, et al. (2007) "Negative vaccination" by specific CD4 T cell tolerisation enhances virus-specific protective antibody responses. PLoS ONE 2: e1162.
32. Ise W, Kohyama M, Schraml BU, Zhang T, Schwer B, et al. (2011) The transcription factor BATF controls the global regulators of class-switch recombination in both B cells and T cells. Nat Immunol 12: 536-543.
33. Singh A, Wuthrich M, Klein B, Suresh M, (2007) Indirect regulation of CD4 T-cell responses by tumor necrosis factor receptors in an acute viral infection. J Virol 81: 6502-6512.
34. Morita R, Schmitt N, Bentebibel SE, Ranganathan R, Bourdery L, et al. (2011) Human blood CXCR5(+)CD4(+) T cells are counterparts of T follicular cells and contain specific subsets that differentially support antibody secretion. Immunity 34: 108-121.
35. Barbosa RR, Silva SP, Silva SL, Melo AC, Pedro E, et al. (2011) Primary B-Cell Deficiencies Reveal a Link between Human IL-17-Producing CD4 T-Cell Homeostasis and B-Cell Differentiation. PLoS ONE 6: e22848.
36. Croft M, Swain SL, (1992) Analysis of CD4+ T cells that provide contact-dependent bystander help to B cells. J Immunol 149: 3157-3165.
37. Sangster MY, Riberdy JM, Gonzalez M, Topham DJ, Baumgarth N, et al. (2003) An early CD4+ T cell-dependent immunoglobulin A response to influenza infection in the absence of key cognate T-B interactions. J Exp Med 198: 1011-1021.
38. Perona-Wright G, Mohrs K, Mohrs M, (2010) Sustained signaling by canonical helper T cell cytokines throughout the reactive lymph node. Nat Immunol 11: 520-526.
39. Manca F, Kunkl A, Fenoglio D, Fowler A, Sercarz E, et al. (1985) Constraints in T-B cooperation related to epitope topology on E. coli beta-galactosidase. I. The fine specificity of T cells dictates the fine specificity of antibodies directed to conformation-dependent determinants. Eur J Immunol 15: 345-350.
40. Manca F, Fenoglio D, Kunkl A, Cambiaggi C, Sasso M, et al. (1988) Differential Activation of T Cell Clones Stimulated by Macrophages Exposed to Antigen Complexed with Monoclonal Antibodies. Journal of Immunology 9: 2893-2898.
41. Davidson HW, Watts C, (1989) Epitope-directed processing of specific antigen by B lymphocytes. Journal of Cell Biology 109: 85-92.
42. Simitsek PD, Campbell DG, Lanzavecchia A, Fairweather N, Watts C, (1995) Modulation of antigen processing by bound antibodies can boost or suppress class II major histocompatibility complex presentation of different T cell determinants [see comments]. Journal of Experimental Medicine 181: 1957-1963.
43. Moss CX, Tree TI, Watts C, (2007) Reconstruction of a pathway of antigen processing and class II MHC peptide capture. Embo J 26: 2137-2147.
44. McLellan AD, (2009) Exosome release by primary B cells. Crit Rev Immunol 29: 203-217.
45. Harvey BP, Quan TE, Rudenga BJ, Roman RM, Craft J, et al. (2008) Editing antigen presentation: antigen transfer between human B lymphocytes and macrophages mediated by class A scavenger receptors. J Immunol 181: 4043-4051.
46. Schwickert TA, Victora GD, Fooksman DR, Kamphorst AO, Mugnier MR, et al. (2011) A dynamic T cell-limited checkpoint regulates affinity-dependent B cell entry into the germinal center. J Exp Med.
47. Depoil D, Zaru R, Guiraud M, Chauveau A, Harriague J, et al. (2005) Immunological synapses are versatile structures enabling selective T cell polarization. Immunity 22: 185-194.