Alendronate retards the progression of lumbar intervertebral disc degeneration in ovariectomized rats

Bone

Volumn 55, Issue 2, 2013, Pages 439-448

  Luo, Yang ^a   Zhang, Liu ^a,b   Wang, Wen Ya ^b   Hu, Qi Feng ^b   Song, Hui Ping ^b   Su, Yan Ling ^a   Zhang, Ying Ze ^a  

^a HEBEI MEDICAL UNIVERSITY   (China)

^b HEBEI UNITED UNIVERSITY   (China)

Author keywords

Alendronate; Biomechanics; Disc degeneration; Micro computed tomography; Ovariectomy

Indexed keywords

AGGRECAN; ALENDRONIC ACID; COLLAGEN TYPE 1; COLLAGEN TYPE 2; COLLAGENASE 3; INTERSTITIAL COLLAGENASE; MESSENGER RNA; PLACEBO; SODIUM CHLORIDE; STROMELYSIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOMECHANICS; BONE DENSITY; BONE MASS; BONE STRENGTH; BONE STRUCTURE; CARTILAGE; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE COURSE; DRUG EFFICACY; DRUG MECHANISM; FEMALE; HISTOPATHOLOGY; INTERVERTEBRAL DISK DEGENERATION; LUMBAR SPINE; MICRO-COMPUTED TOMOGRAPHY; NONHUMAN; OSTEOPOROSIS; OVARIECTOMY; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION;

ABSORPTIOMETRY, PHOTON; ALENDRONATE; ANIMALS; BIOMECHANICS; BONE DENSITY; BONE DENSITY CONSERVATION AGENTS; COMPRESSIVE STRENGTH; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; FEMALE; IMMUNOHISTOCHEMISTRY; INTERVERTEBRAL DISC DEGENERATION; LUMBAR VERTEBRAE; OSTEOPOROSIS; OVARIECTOMY; RATS; RATS, SPRAGUE-DAWLEY; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; X-RAY MICROTOMOGRAPHY;

EID: 84878898589     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2013.03.002     Document Type: Article

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