Lessons learned from experimental myocarditis

Herz

Volumn 37, Issue 8, 2012, Pages 817-821

  Matsumori, A ^a  

^a TOKYO MEDICAL UNIVERSITY   (Japan)

Author keywords

Encephalomyocarditis (EMC) virus; Light chain immunoglobulins; Renin angiotension aldosterone system (RAAS); Treatment; Troponin I antibodies

Indexed keywords

ALDOSTERONE ANTAGONIST; AMLODIPINE; ANGIOTENSIN RECEPTOR ANTAGONIST; AUTOANTIBODY; CALCIUM; CALCIUM CHANNEL BLOCKING AGENT; CETIRIZINE; DILTIAZEM; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; EPLERENONE; FREE IMMUNOGLOBULIN LIGHT CHAIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOGLOBULIN LIGHT CHAIN; NIFEDIPINE; TROPONIN I; UNCLASSIFIED DRUG; VERAPAMIL; ANTIINFLAMMATORY AGENT; CYTOKINE;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CALCIUM TRANSPORT; CYTOKINE PRODUCTION; DISEASE MODEL; DRUG MECHANISM; ENCEPHALOMYOCARDITIS VIRUS; HEART INJURY; HUMAN; INFLAMMATION; MAST CELL; MYOCARDITIS; NONHUMAN; PATHOGENESIS; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; VIRUS MYOCARDITIS; ANIMAL; BIOLOGICAL MODEL; CONGESTIVE CARDIOMYOPATHY; HEART FAILURE; IMMUNOLOGY; MOUSE;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CARDIOMYOPATHY, DILATED; CYTOKINES; DISEASE MODELS, ANIMAL; HEART FAILURE; HUMANS; MICE; MODELS, IMMUNOLOGICAL; MYOCARDITIS;

EID: 84878895672     PISSN: 03409937     EISSN: 16156692     Source Type: Journal    
DOI: 10.1007/s00059-012-3692-z     Document Type: Article

References (28)

1. JCS joint Working Group (2011) Guidelines for diagnosis and treatment of myocarditis. Circ J 75:734-743
2. Matsumori A (1993) Animal models: pathological findings and therapeutic considerations. In: Banatvala J (ed) Viral infection of the heart. Edward Arnolds, London, pp 110-137
3. Ukimura A, Izumi T, Matsumori A (2000) A National survey on myocarditis associated with the 2009 influenza A (H1N1) pandemic in Japan. Circ J 101:2193-2219
4. Matsumori A (2005) Hepatitis C virus infection and cardiomyopathies. Circ Res 96:144-147
5. Matsumori A, Matoba Y, Nishio R et al (1996) Detection of hepatitis C virus RNA from the heart of patients with hypertrophic cardiomyopathy. Biochem Biophys Res Commun 222: 678-682
6. Matsumori A, Matova Y, Sasayama S (1995) Dilated cardiomyopathy associated with hepatitis C virus infection. Circulation 92:2519-2525
7. Caforio AL, Grazzini M, Mann JM et al (1992) Identification of alpha-and beta-cardiac myosin heavy chain isoforms as major autoantigens in dilated cardiomyopathy. Circulation 85:1734-1742
8. Schultheiss HP, Kuhl U, Janda I et al (1988) Antibody-mediated enhancement of calcium permeability in cardiac myocytes. J Exp Med 168:2105-2119
9. Tominaga M, Matsumori A, Horie M et al (1993) Activation of Ca-permeable cation channels by myocarditis-associated antibody in guinea pig ventriculae myocytes. J Clin Invest 91:1231-1234
10. Nishimura H, Okazaki T, Tanaka Y et al (2001) Autoimmue dilated cardiomyopathy in PD-1 receptor deficient mice. Science 291:319-322
11. Okazaki T, Tnanaka Y, Nisio R et al (2003) Autoantibodies against cardiac troponin I are responsible for dilated cardiomyopathy in PD-1-dificient mice. Nat Med 9:1477-1483
12. Matsumori A, Shimada T, Hattori H et al (2011) Autoantibodies against cardiac troponin I in patients presenting with myocarditis. CVD Prev Control 6:41-46
13. Hara M, Matsumori A, Ono K et al (1999) Mast cells cause apoptosis on cardiomyocytes and prolifiration of other intramyocardial cells in vitro. Circulation 100:1443-1449
14. Kitaura-Inenaga K, Hara M, Higuchi H et al (2003) Gene expression of cardiac mast cell chymase and tryptase in a murine model of heart failure caused by viral myocarditis. Circ J 67:881-884
15. Matsumori A, Yamamoto K, Shimada M (2010) Cetirizine a histamine H1 receptor antagonist improves viral myocarditis. J Inflamm (Lond) 7:39
16. Brown NJ (2008) Aldosterone and vascular inflammation. Hypertension 51:161-167
17. Griending KK, Minieri CA, Ollerenshaw JD, Alexander RW (1994) Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells. Circ Res 74:1141-1148
18. Okamura A, Rakugi H, Ohishi M et al (1999) Upregulation of rennin-angiotensin system during differention of monocytes to macrophages. J Hypertens 17:537-545.
19. Yamamoto K, Shioi T, Uchiyama K et al (2003) Attention of virus-induced myocardial injury by inhibition of the angiotensin II type 1 receptor signal and decreased nuclear factor-kappa â activation in knock-out mice. J Am Coll Cardiol 42:2000-2006
20. Wahed MI, Watanabe K, Ma M et al (2005) Effects of eplerenone, a selective aldsterone blocker, on the progression of left ventricular dysfunction and remodeling in rats with dilated cardiomyopathy. Pharmacology 73:81-88
21. Higuchi H, Hara M, Yamamoto K et al (2008) Mast cells play a critical role in the pathogenesis of viral myocarditis. Circulation 118:363-372
22. Xiao J, Shimada M, Liu W et al (2009) Anti-inflammatory effects of eplerenone on viral myocarditis. Eur J Heart Fail 11:349-353
23. Matsumori A, Nunokawa Y, Sasayama S (2000) Nifedipine inhibits activation of transcription factor NF-kappaB. Life Sci 67:2655-2661
24. Liu W, Matsumori A (2011) Calcium channel blockers and modulation of innate immunity. Curr Opin Infect Dis 24:254-258
25. Matsumori A, Nishio R, Nose Y (2010) Calcium channel blockers differentially modulate cytokine production by peripheral blood mononuclear cells. Circ J 74:567-571
26. Liu W, Shimada M, Xiao J et al (2009) Nifedipine inhibits the activation of inflammatory and immune reactions in viral myocarditis. Life Sci 85:235-240
27. Matsumori A, Shimada M, Jie X et al (2010) Effect of free immunoglobulin light chain on viral myocarditis. Circ Res 106:1533-1540
28. Matsumori A (2009) Global alert and response network for hepatitis C virus-derived heart diseases: a call to action. CVD Prev Control 4:109-118