-
1
-
-
80051580618
-
Cancer statistics, 2011: the impact of eliminating socioeconomic and racial disparities on premature cancer deaths
-
10.3322/caac.20121, 21685461
-
Siegel R, Ward E, Brawley O, Jemal A. Cancer statistics, 2011: the impact of eliminating socioeconomic and racial disparities on premature cancer deaths. CA Cancer J Clin 2011, 61:212-236. 10.3322/caac.20121, 21685461.
-
(2011)
CA Cancer J Clin
, vol.61
, pp. 212-236
-
-
Siegel, R.1
Ward, E.2
Brawley, O.3
Jemal, A.4
-
2
-
-
67249117049
-
Potential etiologic and functional implications of genome-wide association loci for human diseases and traits
-
10.1073/pnas.0903103106, 2687147, 19474294
-
Hindorff LA, Sethupathy P, Junkins HA, Ramos EM, Mehta JP, Collins FS, Manolio TA. Potential etiologic and functional implications of genome-wide association loci for human diseases and traits. Proc Natl Acad Sci USA 2009, 106:9362-9367. 10.1073/pnas.0903103106, 2687147, 19474294.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 9362-9367
-
-
Hindorff, L.A.1
Sethupathy, P.2
Junkins, H.A.3
Ramos, E.M.4
Mehta, J.P.5
Collins, F.S.6
Manolio, T.A.7
-
3
-
-
33846631884
-
Common genetic variants account for differences in gene expression among ethnic groups
-
10.1038/ng1955, 3005333, 17206142
-
Spielman RS, Bastone LA, Burdick JT, Morley M, Ewens WJ, Cheung VG. Common genetic variants account for differences in gene expression among ethnic groups. Nat Genet 2007, 39:226-231. 10.1038/ng1955, 3005333, 17206142.
-
(2007)
Nat Genet
, vol.39
, pp. 226-231
-
-
Spielman, R.S.1
Bastone, L.A.2
Burdick, J.T.3
Morley, M.4
Ewens, W.J.5
Cheung, V.G.6
-
4
-
-
45149106353
-
Integrating large-scale functional genomic data to dissect the complexity of yeast regulatory networks
-
10.1038/ng.167, 2573859, 18552845
-
Zhu J, Zhang B, Smith EN, Drees B, Brem RB, Kruglyak L, Bumgarner RE, Schadt EE. Integrating large-scale functional genomic data to dissect the complexity of yeast regulatory networks. Nat Genet 2008, 40:854-861. 10.1038/ng.167, 2573859, 18552845.
-
(2008)
Nat Genet
, vol.40
, pp. 854-861
-
-
Zhu, J.1
Zhang, B.2
Smith, E.N.3
Drees, B.4
Brem, R.B.5
Kruglyak, L.6
Bumgarner, R.E.7
Schadt, E.E.8
-
5
-
-
77950460661
-
Understanding mechanisms underlying human gene expression variation with RNA sequencing
-
10.1038/nature08872, 3089435, 20220758
-
Pickrell JK, Marioni JC, Pai AA, Degner JF, Engelhardt BE, Nkadori E, Veyrieras JB, Stephens M, Gilad Y, Pritchard JK. Understanding mechanisms underlying human gene expression variation with RNA sequencing. Nature 2010, 464:768-772. 10.1038/nature08872, 3089435, 20220758.
-
(2010)
Nature
, vol.464
, pp. 768-772
-
-
Pickrell, J.K.1
Marioni, J.C.2
Pai, A.A.3
Degner, J.F.4
Engelhardt, B.E.5
Nkadori, E.6
Veyrieras, J.B.7
Stephens, M.8
Gilad, Y.9
Pritchard, J.K.10
-
6
-
-
79751516976
-
Assessing gene length biases in gene set analysis of Genome-Wide Association Studies
-
10.1504/IJCBDD.2010.038394, 21297229
-
Jia P, Tian J, Zhao Z. Assessing gene length biases in gene set analysis of Genome-Wide Association Studies. Int J Comput Biol Drug Des 2010, 3:297-310. 10.1504/IJCBDD.2010.038394, 21297229.
-
(2010)
Int J Comput Biol Drug Des
, vol.3
, pp. 297-310
-
-
Jia, P.1
Tian, J.2
Zhao, Z.3
-
7
-
-
79959735144
-
Gene set analysis of genome-wide association studies: methodological issues and perspectives
-
Wang L, Jia P, Wolfinger RD, Chen X, Zhao Z. Gene set analysis of genome-wide association studies: methodological issues and perspectives. Genomics 2011, 98:1-8.
-
(2011)
Genomics
, vol.98
, pp. 1-8
-
-
Wang, L.1
Jia, P.2
Wolfinger, R.D.3
Chen, X.4
Zhao, Z.5
-
8
-
-
78549251736
-
Analysing biological pathways in genome-wide association studies
-
10.1038/nrg2884, 21085203
-
Wang K, Li M, Hakonarson H. Analysing biological pathways in genome-wide association studies. Nat Rev Genet 2010, 11:843-854. 10.1038/nrg2884, 21085203.
-
(2010)
Nat Rev Genet
, vol.11
, pp. 843-854
-
-
Wang, K.1
Li, M.2
Hakonarson, H.3
-
9
-
-
34249663294
-
Analyzing gene expression data in terms of gene sets: methodological issues
-
10.1093/bioinformatics/btm051, 17303618
-
Goeman JJ, Buhlmann P. Analyzing gene expression data in terms of gene sets: methodological issues. Bioinformatics 2007, 23:980-987. 10.1093/bioinformatics/btm051, 17303618.
-
(2007)
Bioinformatics
, vol.23
, pp. 980-987
-
-
Goeman, J.J.1
Buhlmann, P.2
-
10
-
-
67649584052
-
Gene Ontology Analysis of GWA Study Data Sets Provides Insights into the Biology of Bipolar Disorder
-
10.1016/j.ajhg.2009.05.011, 2706963, 19539887
-
Holmans P, Green EK, Pahwa JS, Ferreira MAR, Purcell SM, Sklar P, Owen MJ, O'Donovan MC, Craddock N, Consor WTCC. Gene Ontology Analysis of GWA Study Data Sets Provides Insights into the Biology of Bipolar Disorder. Am J Hum Genet 2009, 85:13-24. 10.1016/j.ajhg.2009.05.011, 2706963, 19539887.
-
(2009)
Am J Hum Genet
, vol.85
, pp. 13-24
-
-
Holmans, P.1
Green, E.K.2
Pahwa, J.S.3
Ferreira, M.A.R.4
Purcell, S.M.5
Sklar, P.6
Owen, M.J.7
O'Donovan, M.C.8
Craddock, N.9
Consor, W.T.C.C.10
-
11
-
-
77953123145
-
Insights into Colon Cancer Etiology via a Regularized Approach to Gene Set Analysis of GWAS Data
-
10.1016/j.ajhg.2010.04.014, 3032068, 20560206
-
Chen LS, Hutter CM, Potter JD, Liu Y, Prentice RL, Peters U, Hsu L. Insights into Colon Cancer Etiology via a Regularized Approach to Gene Set Analysis of GWAS Data. Am J Hum Genet 2010, 86:860-871. 10.1016/j.ajhg.2010.04.014, 3032068, 20560206.
-
(2010)
Am J Hum Genet
, vol.86
, pp. 860-871
-
-
Chen, L.S.1
Hutter, C.M.2
Potter, J.D.3
Liu, Y.4
Prentice, R.L.5
Peters, U.6
Hsu, L.7
-
12
-
-
67651053605
-
Pathway analysis by adaptive combination of P-values
-
10.1002/gepi.20422, 2790032, 19333968
-
Yu K, Li Q, Bergen AW, Pfeiffer RM, Rosenberg PS, Caporaso N, Kraft P, Chatterjee N. Pathway analysis by adaptive combination of P-values. Genet Epidemiol 2009, 33:700-709. 10.1002/gepi.20422, 2790032, 19333968.
-
(2009)
Genet Epidemiol
, vol.33
, pp. 700-709
-
-
Yu, K.1
Li, Q.2
Bergen, A.W.3
Pfeiffer, R.M.4
Rosenberg, P.S.5
Caporaso, N.6
Kraft, P.7
Chatterjee, N.8
-
13
-
-
27344435774
-
Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles
-
10.1073/pnas.0506580102, 1239896, 16199517
-
Subramanian A, Tamayo P, Mootha VK, Mukherjee S, Ebert BL, Gillette MA, Paulovich A, Pomeroy SL, Golub TR, Lander ES, Mesirov JP. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci USA 2005, 102:15545-15550. 10.1073/pnas.0506580102, 1239896, 16199517.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 15545-15550
-
-
Subramanian, A.1
Tamayo, P.2
Mootha, V.K.3
Mukherjee, S.4
Ebert, B.L.5
Gillette, M.A.6
Paulovich, A.7
Pomeroy, S.L.8
Golub, T.R.9
Lander, E.S.10
Mesirov, J.P.11
-
14
-
-
23144464901
-
WebGestalt: an integrated system for exploring gene sets in various biological contexts
-
10.1093/nar/gki475, 1160236, 15980575
-
Zhang B, Kirov S, Snoddy J. WebGestalt: an integrated system for exploring gene sets in various biological contexts. Nucleic Acids Res 2005, 33:W741-748. 10.1093/nar/gki475, 1160236, 15980575.
-
(2005)
Nucleic Acids Res
, vol.33
-
-
Zhang, B.1
Kirov, S.2
Snoddy, J.3
-
15
-
-
36549027355
-
GSEA-P: a desktop application for Gene Set Enrichment Analysis
-
10.1093/bioinformatics/btm369, 17644558
-
Subramanian A, Kuehn H, Gould J, Tamayo P, Mesirov JP. GSEA-P: a desktop application for Gene Set Enrichment Analysis. Bioinformatics 2007, 23:3251-3253. 10.1093/bioinformatics/btm369, 17644558.
-
(2007)
Bioinformatics
, vol.23
, pp. 3251-3253
-
-
Subramanian, A.1
Kuehn, H.2
Gould, J.3
Tamayo, P.4
Mesirov, J.P.5
-
16
-
-
36249029788
-
Pathway-based approaches for analysis of genomewide association studies
-
10.1086/522374, 2276352, 17966091
-
Wang K, Li M, Bucan M. Pathway-based approaches for analysis of genomewide association studies. Am J Hum Genet 2007, 81:1278-1283. 10.1086/522374, 2276352, 17966091.
-
(2007)
Am J Hum Genet
, vol.81
, pp. 1278-1283
-
-
Wang, K.1
Li, M.2
Bucan, M.3
-
17
-
-
56649097558
-
GSEA-SNP: applying gene set enrichment analysis to SNP data from genome-wide association studies
-
10.1093/bioinformatics/btn516, 18854360
-
Holden M, Deng S, Wojnowski L, Kulle B. GSEA-SNP: applying gene set enrichment analysis to SNP data from genome-wide association studies. Bioinformatics 2008, 24:2784-2785. 10.1093/bioinformatics/btn516, 18854360.
-
(2008)
Bioinformatics
, vol.24
, pp. 2784-2785
-
-
Holden, M.1
Deng, S.2
Wojnowski, L.3
Kulle, B.4
-
18
-
-
77954246243
-
I-GSEA4GWAS: a web server for identification of pathways/gene sets associated with traits by applying an improved gene set enrichment analysis to genome-wide association study
-
10.1093/nar/gkq324, 2896119, 20435672
-
Zhang K, Cui S, Chang S, Zhang L, Wang J. i-GSEA4GWAS: a web server for identification of pathways/gene sets associated with traits by applying an improved gene set enrichment analysis to genome-wide association study. Nucleic Acids Res 2010, 38:W90-95. 10.1093/nar/gkq324, 2896119, 20435672.
-
(2010)
Nucleic Acids Res
, vol.38
-
-
Zhang, K.1
Cui, S.2
Chang, S.3
Zhang, L.4
Wang, J.5
-
19
-
-
70349991890
-
The SNP ratio test: pathway analysis of genome-wide association datasets
-
10.1093/bioinformatics/btp448, 19620097
-
O'Dushlaine C, Kenny E, Heron EA, Segurado R, Gill M, Morris DW, Corvin A. The SNP ratio test: pathway analysis of genome-wide association datasets. Bioinformatics 2009, 25:2762-2763. 10.1093/bioinformatics/btp448, 19620097.
-
(2009)
Bioinformatics
, vol.25
, pp. 2762-2763
-
-
O'Dushlaine, C.1
Kenny, E.2
Heron, E.A.3
Segurado, R.4
Gill, M.5
Morris, D.W.6
Corvin, A.7
-
20
-
-
79951966907
-
An efficient hierarchical generalized linear mixed model for pathway analysis of genome-wide association studies
-
10.1093/bioinformatics/btq728, 3042187, 21266443
-
Wang L, Jia P, Wolfinger RD, Chen X, Grayson BL, Aune TM, Zhao Z. An efficient hierarchical generalized linear mixed model for pathway analysis of genome-wide association studies. Bioinformatics 2011, 27:686-692. 10.1093/bioinformatics/btq728, 3042187, 21266443.
-
(2011)
Bioinformatics
, vol.27
, pp. 686-692
-
-
Wang, L.1
Jia, P.2
Wolfinger, R.D.3
Chen, X.4
Grayson, B.L.5
Aune, T.M.6
Zhao, Z.7
-
21
-
-
84896380770
-
-
CGEMS
-
CGEMS. , http://cgems.cancer.gov/data_access.html
-
-
-
-
22
-
-
84896341024
-
Prostate cancer CGEMS GWAS dataset through dbGAP
-
Prostate cancer CGEMS GWAS dataset through dbGAP. , http://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000207.v1.p1
-
-
-
-
23
-
-
84896359968
-
Prostate, Lung, Colon and Ovarian Cancer Screening Trial
-
Prostate, Lung, Colon and Ovarian Cancer Screening Trial. , http://prevention.cancer.gov/plco
-
-
-
-
24
-
-
34247548755
-
Genome-wide association study of prostate cancer identifies a second risk locus at 8q24
-
10.1038/ng2022, 17401363
-
Yeager M, Orr N, Hayes RB, Jacobs KB, Kraft P, Wacholder S, Minichiello MJ, Fearnhead P, Yu K, Chatterjee N, et al. Genome-wide association study of prostate cancer identifies a second risk locus at 8q24. Nat Genet 2007, 39:645-649. 10.1038/ng2022, 17401363.
-
(2007)
Nat Genet
, vol.39
, pp. 645-649
-
-
Yeager, M.1
Orr, N.2
Hayes, R.B.3
Jacobs, K.B.4
Kraft, P.5
Wacholder, S.6
Minichiello, M.J.7
Fearnhead, P.8
Yu, K.9
Chatterjee, N.10
-
25
-
-
34249709906
-
Gene expression profiles of prostate cancer reveal involvement of multiple molecular pathways in the metastatic process
-
10.1186/1471-2407-7-64, 1865555, 17430594
-
Chandran UR, Ma C, Dhir R, Bisceglia M, Lyons-Weiler M, Liang W, Michalopoulos G, Becich M, Monzon FA. Gene expression profiles of prostate cancer reveal involvement of multiple molecular pathways in the metastatic process. BMC Cancer 2007, 7:64. 10.1186/1471-2407-7-64, 1865555, 17430594.
-
(2007)
BMC Cancer
, vol.7
, pp. 64
-
-
Chandran, U.R.1
Ma, C.2
Dhir, R.3
Bisceglia, M.4
Lyons-Weiler, M.5
Liang, W.6
Michalopoulos, G.7
Becich, M.8
Monzon, F.A.9
-
26
-
-
4344561557
-
Gene expression alterations in prostate cancer predicting tumor aggression and preceding development of malignancy
-
10.1200/JCO.2004.05.158, 15254046
-
Yu YP, Landsittel D, Jing L, Nelson J, Ren B, Liu L, McDonald C, Thomas R, Dhir R, Finkelstein S, et al. Gene expression alterations in prostate cancer predicting tumor aggression and preceding development of malignancy. J Clin Oncol 2004, 22:2790-2799. 10.1200/JCO.2004.05.158, 15254046.
-
(2004)
J Clin Oncol
, vol.22
, pp. 2790-2799
-
-
Yu, Y.P.1
Landsittel, D.2
Jing, L.3
Nelson, J.4
Ren, B.5
Liu, L.6
McDonald, C.7
Thomas, R.8
Dhir, R.9
Finkelstein, S.10
-
27
-
-
84858983547
-
KEGG for integration and interpretation of large-scale molecular data sets
-
10.1093/nar/gkr988, 3245020, 22080510
-
Kanehisa M, Goto S, Sato Y, Furumichi M, Tanabe M. KEGG for integration and interpretation of large-scale molecular data sets. Nucleic Acids Res 2012, 40:D109-114. 10.1093/nar/gkr988, 3245020, 22080510.
-
(2012)
Nucleic Acids Res
, vol.40
-
-
Kanehisa, M.1
Goto, S.2
Sato, Y.3
Furumichi, M.4
Tanabe, M.5
-
28
-
-
0037249538
-
PGDB: a curated and integrated database of genes related to the prostate
-
10.1093/nar/gkg008, 165455, 12520005
-
Li LC, Zhao H, Shiina H, Kane CJ, Dahiya R. PGDB: a curated and integrated database of genes related to the prostate. Nucleic Acids Res 2003, 31:291-293. 10.1093/nar/gkg008, 165455, 12520005.
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 291-293
-
-
Li, L.C.1
Zhao, H.2
Shiina, H.3
Kane, C.J.4
Dahiya, R.5
-
29
-
-
77956192274
-
Common variants conferring risk of schizophrenia: a pathway analysis of GWAS data
-
10.1016/j.schres.2010.07.001, 2933424, 20659789
-
Jia P, Wang L, Meltzer HY, Zhao Z. Common variants conferring risk of schizophrenia: a pathway analysis of GWAS data. Schizophr Res 2010, 122:38-42. 10.1016/j.schres.2010.07.001, 2933424, 20659789.
-
(2010)
Schizophr Res
, vol.122
, pp. 38-42
-
-
Jia, P.1
Wang, L.2
Meltzer, H.Y.3
Zhao, Z.4
-
30
-
-
84896341966
-
GenGen
-
GenGen. , http://www.openbioinformatics.org/gengen/
-
-
-
-
31
-
-
34548292504
-
PLINK: a tool set for whole-genome association and population-based linkage analyses
-
10.1086/519795, 1950838, 17701901
-
Purcell S, Neale B, Todd-Brown K, Thomas L, Ferreira MA, Bender D, Maller J, Sklar P, de Bakker PI, Daly MJ, Sham PC. PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet 2007, 81:559-575. 10.1086/519795, 1950838, 17701901.
-
(2007)
Am J Hum Genet
, vol.81
, pp. 559-575
-
-
Purcell, S.1
Neale, B.2
Todd-Brown, K.3
Thomas, L.4
Ferreira, M.A.5
Bender, D.6
Maller, J.7
Sklar, P.8
de Bakker, P.I.9
Daly, M.J.10
Sham, P.C.11
-
32
-
-
84896377215
-
The GSEA home
-
The GSEA home. , http://www.broadinstitute.org/gsea/index.jsp
-
-
-
-
34
-
-
0034651980
-
Interleukin-6 induces prostate cancer cell growth accompanied by activation of stat3 signaling pathway
-
10.1002/(SICI)1097-0045(20000215)42:3<239::AID-PROS10>3.0.CO;2-G, 10639195
-
Lou W, Ni Z, Dyer K, Tweardy DJ, Gao AC. Interleukin-6 induces prostate cancer cell growth accompanied by activation of stat3 signaling pathway. Prostate 2000, 42:239-242. 10.1002/(SICI)1097-0045(20000215)42:3<239::AID-PROS10>3.0.CO;2-G, 10639195.
-
(2000)
Prostate
, vol.42
, pp. 239-242
-
-
Lou, W.1
Ni, Z.2
Dyer, K.3
Tweardy, D.J.4
Gao, A.C.5
-
35
-
-
0034163461
-
Inhibition of constitutively activated stat3 signaling pathway suppresses growth of prostate cancer cells
-
Ni Z, Lou W, Leman ES, Gao AC. Inhibition of constitutively activated stat3 signaling pathway suppresses growth of prostate cancer cells. Cancer Research 2000, 60:1225-1228.
-
(2000)
Cancer Research
, vol.60
, pp. 1225-1228
-
-
Ni, Z.1
Lou, W.2
Leman, E.S.3
Gao, A.C.4
-
36
-
-
34547609006
-
Expression levels of the JAK/STAT pathway in the transition from hormone-sensitive to hormone-refractory prostate cancer
-
10.1038/sj.bjc.6603871, 2360337, 17595657
-
Tam L, McGlynn LM, Traynor P, Mukherjee R, Bartlett JM, Edwards J. Expression levels of the JAK/STAT pathway in the transition from hormone-sensitive to hormone-refractory prostate cancer. Br J Cancer 2007, 97:378-383. 10.1038/sj.bjc.6603871, 2360337, 17595657.
-
(2007)
Br J Cancer
, vol.97
, pp. 378-383
-
-
Tam, L.1
McGlynn, L.M.2
Traynor, P.3
Mukherjee, R.4
Bartlett, J.M.5
Edwards, J.6
-
37
-
-
1542515338
-
A census of human cancer genes
-
10.1038/nrc1299, 2665285, 14993899
-
Futreal PA, Coin L, Marshall M, Down T, Hubbard T, Wooster R, Rahman N, Stratton MR. A census of human cancer genes. Nat Rev Cancer 2004, 4:177-183. 10.1038/nrc1299, 2665285, 14993899.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 177-183
-
-
Futreal, P.A.1
Coin, L.2
Marshall, M.3
Down, T.4
Hubbard, T.5
Wooster, R.6
Rahman, N.7
Stratton, M.R.8
-
38
-
-
80053478943
-
Comparisons of seven algorithms for pathway analysis using the WTCCC Crohn's Disease dataset
-
10.1186/1756-0500-4-386, 3199264, 21981765
-
Gui H, Li M, Sham PC, Cherny SS. Comparisons of seven algorithms for pathway analysis using the WTCCC Crohn's Disease dataset. BMC Res Notes 2011, 4:386. 10.1186/1756-0500-4-386, 3199264, 21981765.
-
(2011)
BMC Res Notes
, vol.4
, pp. 386
-
-
Gui, H.1
Li, M.2
Sham, P.C.3
Cherny, S.S.4
-
39
-
-
39949083558
-
Mining for JAK-STAT mutations in cancer
-
10.1016/j.tibs.2007.12.002, 18291658
-
Constantinescu SN, Girardot M, Pecquet C. Mining for JAK-STAT mutations in cancer. Trends Biochem Sci 2008, 33:122-131. 10.1016/j.tibs.2007.12.002, 18291658.
-
(2008)
Trends Biochem Sci
, vol.33
, pp. 122-131
-
-
Constantinescu, S.N.1
Girardot, M.2
Pecquet, C.3
-
40
-
-
33846903838
-
Cytokine receptor signaling through the Jak-Stat-Socs pathway in disease
-
10.1016/j.molimm.2006.11.025, 17208301
-
O'Sullivan LA, Liongue C, Lewis RS, Stephenson SE, Ward AC. Cytokine receptor signaling through the Jak-Stat-Socs pathway in disease. Mol Immunol 2007, 44:2497-2506. 10.1016/j.molimm.2006.11.025, 17208301.
-
(2007)
Mol Immunol
, vol.44
, pp. 2497-2506
-
-
O'Sullivan, L.A.1
Liongue, C.2
Lewis, R.S.3
Stephenson, S.E.4
Ward, A.C.5
-
41
-
-
0034029101
-
Cytokine receptor signaling pathways
-
10.1067/mai.2000.106899, 10808165
-
Leonard WJ, Lin JX. Cytokine receptor signaling pathways. J Allergy Clin Immunol 2000, 105:877-888. 10.1067/mai.2000.106899, 10808165.
-
(2000)
J Allergy Clin Immunol
, vol.105
, pp. 877-888
-
-
Leonard, W.J.1
Lin, J.X.2
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