Dermal γδ T cells - A new player in the pathogenesis of psoriasis

International Immunopharmacology

Volumn 16, Issue 3, 2013, Pages 388-391

  Cai, Yihua ^a   Fleming, Chris ^a   Yan, Jun ^a  

^a University of Louisville School of Medicine   (United States)

Author keywords

Dermal T cells; IL 17; Psoriasis

Indexed keywords

IMIQUIMOD; INTERLEUKIN 17; INTERLEUKIN 23; T LYMPHOCYTE RECEPTOR; T LYMPHOCYTE RECEPTOR DELTA CHAIN;

CELL POPULATION; DERMIS; DISEASE SEVERITY; GAMMA DELTA T LYMPHOCYTE; HUMAN; IMMUNOPATHOGENESIS; IMMUNOSTIMULATION; NONHUMAN; PRIORITY JOURNAL; PSORIASIS; REVIEW; SKIN CELL; TH1 CELL; TH17 CELL;

ANIMALS; HUMANS; INTERLEUKIN-17; PSORIASIS; SKIN; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES;

EID: 84878838607     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2013.02.018     Document Type: Review

References (34)

1. F.O. Nestle, D.H. Kaplan, and J. Barker Psoriasis N Engl J Med 361 2009 496 509
2. G.K. Perera, P. Di Meglio, and F.O. Nestle Psoriasis Annu Rev Pathol 7 2012 385 422
3. W. Lew, A.M. Bowcock, and J.G. Krueger Psoriasis vulgaris: cutaneous lymphoid tissue supports T-cell activation and "Type 1" inflammatory gene expression Trends Immunol 25 2004 295 305 (Pubitemid 38610353)
4. L. Steinman A brief history of T(H)17, the first major revision in the T(H)1/T(H)2 hypothesis of T cell-mediated tissue damage Nat Med 13 2007 139 145
5. C.T. Weaver, R.D. Hatton, P.R. Mangan, and L.E. Harrington IL-17 family cytokines and the expanding diversity of effector T cell lineages Annu Rev Immunol 25 2007 821 852 (Pubitemid 46697925)
6. A. Di Cesare, P. Di Meglio, and F.O. Nestle The IL-23/Th17 axis in the immunopathogenesis of psoriasis J Invest Dermatol 129 2009 1339 1350
7. K. Boniface, E. Guignouard, N. Pedretti, M. Garcia, A. Delwail, and F.X. Bernard A role for T cell-derived interleukin 22 in psoriatic skin inflammation Clin Exp Immunol 150 2007 407 415 (Pubitemid 350098734)
8. M.A. Lowes, T. Kikuchi, J. Fuentes-Duculan, I. Cardinale, L.C. Zaba, and A.S. Haider Psoriasis vulgaris lesions contain discrete populations of Th1 and Th17 T cells J Invest Dermatol 128 2008 1207 1211 (Pubitemid 351543220)
9. R. Caruso, E. Botti, M. Sarra, M. Esposito, C. Stolfi, and L. Diluvio Involvement of interleukin-21 in the epidermal hyperplasia of psoriasis Nat Med 15 2009 1013 1015
10. S. Kagami, H.L. Rizzo, J.J. Lee, Y. Koguchi, and A. Blauvelt Circulating Th17, Th22, and Th1 cells are increased in psoriasis J Invest Dermatol 130 2010 1373 1383
11. R.L. O'Brien, C.L. Roark, and W.K. Born IL-17-producing gammadelta T cells Eur J Immunol 39 2009 662 666
12. M.L. Michel, A.C. Keller, C. Paget, M. Fujio, F. Trottein, and P.B. Savage Identification of an IL-17-producing NK1.1(neg) iNKT cell population involved in airway neutrophilia J Exp Med 204 2007 995 1001 (Pubitemid 46798144)
13. B. Martin, K. Hirota, D.J. Cua, B. Stockinger, and M. Veldhoen Interleukin-17-producing gammadelta T cells selectively expand in response to pathogen products and environmental signals Immunity 31 2009 321 330
14. C.E. Sutton, S.J. Lalor, C.M. Sweeney, C.F. Brereton, E.C. Lavelle, and K.H. Mills Interleukin-1 and IL-23 induce innate IL-17 production from gammadelta T cells, amplifying Th17 responses and autoimmunity Immunity 31 2009 331 341
15. A.E. Price, R.L. Reinhardt, H.E. Liang, and R.M. Locksley Marking and quantifying IL-17A-producing cells in vivo PLoS One 7 2012 e39750
16. Y. Cai, X. Shen, C. Ding, C. Qi, K. Li, and X. Li Pivotal role of dermal IL-17-producing gammadelta T cells in skin inflammation Immunity 35 2011 596 610
17. N. Sumaria, B. Roediger, L.G. Ng, J. Qin, R. Pinto, and L.L. Cavanagh Cutaneous immunosurveillance by self-renewing dermal gammadelta T cells J Exp Med 208 2011 505 518
18. E.E. Gray, K. Suzuki, and J.G. Cyster Cutting edge: identification of a motile IL-17-producing gammadelta T cell population in the dermis J Immunol 186 2011 6091 6095
19. + dendritic epidermal cells of adult mice from fetal thymic precursors Nature 344 1990 68 70
20. J.D. Haas, S. Ravens, S. Duber, I. Sandrock, L. Oberdorfer, and E. Kashani Development of interleukin-17-producing gammadelta T cells is restricted to a functional embryonic wave Immunity 37 2012 48 59
21. M. Alaibac, J. Morris, R. Yu, and A.C. Chu T lymphocytes bearing the gamma delta T-cell receptor: a study in normal human skin and pathological skin conditions Br J Dermatol 127 1992 458 462
22. P. Dupuy, M. Heslan, S. Fraitag, T. Hercend, L. Dubertret, and M. Bagot T-cell receptor-gamma/delta bearing lymphocytes in normal and inflammatory human skin J Invest Dermatol 94 1990 764 768 (Pubitemid 20184375)
23. L.M. Ebert, S. Meuter, and B. Moser Homing and function of human skin gammadelta T cells and NK cells: relevance for tumor surveillance J Immunol 176 2006 4331 4336 (Pubitemid 44264412)
24. U. Laggner, P. Di Meglio, G.K. Perera, C. Hundhausen, K.E. Lacy, and N. Ali Identification of a novel proinflammatory human skin-homing Vgamma9Vdelta2 T cell subset with a potential role in psoriasis J Immunol 187 2011 2783 2793
25. K.J. Ness-Schwickerath, C. Jin, and C.T. Morita Cytokine requirements for the differentiation and expansion of IL-17A- and IL-22-producing human Vgamma2Vdelta2 T cells J Immunol 184 2010 7268 7280
26. N. Caccamo, C. La Mendola, V. Orlando, S. Meraviglia, M. Todaro, and G. Stassi Differentiation, phenotype, and function of interleukin-17-producing human Vgamma9Vdelta2 T cells Blood 118 2011 129 138
27. J.R. Chan, W. Blumenschein, E. Murphy, C. Diveu, M. Wiekowski, and S. Abbondanzo IL-23 stimulates epidermal hyperplasia via TNF and IL-20R2-dependent mechanisms with implications for psoriasis pathogenesis J Exp Med 203 2006 2577 2587 (Pubitemid 44833335)
28. L. van der Fits, S. Mourits, J.S. Voerman, M. Kant, L. Boon, and J.D. Laman Imiquimod-induced psoriasis-like skin inflammation in mice is mediated via the IL-23/IL-17 axis J Immunol 182 2009 5836 5845
29. + gammadelta T cells are major producers of IL-22 and IL-17 in a murine model of psoriasiform dermatitis J Immunol 187 2011 5026 5031
30. S. Pantelyushin, S. Haak, B. Ingold, P. Kulig, F.L. Heppner, and A.A. Navarini Rorgammat + innate lymphocytes and gammadelta T cells initiate psoriasiform plaque formation in mice J Clin Invest 122 2012 2252 2256
31. T. Mabuchi, T.P. Singh, T. Takekoshi, G.F. Jia, X. Wu, and M.C. Kao CCR6 is required for epidermal trafficking of gammadelta-T cells in an IL-23-induced model of psoriasiform dermatitis J Invest Dermatol 133 2013 164 171
32. C.E. Griffiths, B.E. Strober, P. van de Kerkhof, V. Ho, R. Fidelus-Gort, and N. Yeilding Comparison of ustekinumab and etanercept for moderate-to-severe psoriasis N Engl J Med 362 2010 118 128
33. C. Leonardi, R. Matheson, C. Zachariae, G. Cameron, L. Li, and E. Edson-Heredia Anti-interleukin-17 monoclonal antibody ixekizumab in chronic plaque psoriasis N Engl J Med 366 2012 1190 1199
34. K.A. Papp, C. Leonardi, A. Menter, J.P. Ortonne, J.G. Krueger, and G. Kricorian Brodalumab, an anti-interleukin-17-receptor antibody for psoriasis N Engl J Med 366 2012 1181 1189