메뉴 건너뛰기




Volumn 14, Issue 1, 2010, Pages 13-20

Synthesis and evaluation of antiviral, antitubercular and anticancer activities of some novel thioureas derived from 4-aminobenzohydrazide hydrazones;4-Aminobenzohidrazit hidrazonlarından türetilmiş bazı yeni tiyoürelerin sentezi, antiviral, antitüberküler ve antikanser etkilerinin deǧerlendirilmesi

Author keywords

Anticancer activity; Antiviral activity; Hydrazones; Mycobacterium tuberculosis H37Rv; Thioureas

Indexed keywords


EID: 84878837700     PISSN: None     EISSN: 13090801     Source Type: Journal    
DOI: 10.12991/201014460     Document Type: Article
Times cited : (33)

References (30)
  • 3
    • 41849092228 scopus 로고    scopus 로고
    • N-D-aldopentofuranosyl-N'-[p-(isoamyloxy)phenyl]-thiourea derivatives: Potential anti-TB therapeutic agents
    • Liav A, Angala SK, Brennan PJ, Jackson M. N-D-aldopentofuranosyl-N'-[p-(isoamyloxy)phenyl]-thiourea derivatives: potential anti-TB therapeutic agents. Bioorg Med Chem Lett, 18:2649-2651, 2008.
    • (2008) Bioorg Med Chem Lett , vol.18 , pp. 2649-2651
    • Liav, A.1    Angala, S.K.2    Brennan, P.J.3    Jackson, M.4
  • 4
    • 33846467138 scopus 로고    scopus 로고
    • From actually toxic to highly specific--novel drugs against poxviruses
    • Sliva K, Schnierle B. From actually toxic to highly specific--novel drugs against poxviruses. Virol J. 4:8, 2007.
    • (2007) Virol J. , vol.4 , pp. 8
    • Sliva, K.1    Schnierle, B.2
  • 5
    • 0021673083 scopus 로고
    • Studies antitubercular and antibacterial agents: Preparation of 1-(4-aminobenzoyl)-2-benzalhydrazine and 1-[4-(phenylthio ureido)benzoyl]-2-substituted benzalhydrazine
    • Patel JM, Dave M, Langalia NA, Thaker KA. Studies antitubercular and antibacterial agents: Preparation of 1-(4-aminobenzoyl)-2-benzalhydrazine and 1-[4-(phenylthio ureido)benzoyl]-2-substituted benzalhydrazine. J Indian Chem Soc, 61: 718-720, 1984.
    • (1984) J Indian Chem Soc , vol.61 , pp. 718-720
    • Patel, J.M.1    Dave, M.2    Langalia, N.A.3    Thaker, K.A.4
  • 6
    • 30344482252 scopus 로고    scopus 로고
    • Synthesis and in vitro antitubercular activity of some 1-[(4-sub)phenyl]-3-(4-{1-[(pyridine-4-carbonyl)hydrazono]ethyl}phenyl) thiourea
    • Sriram D, Yogeeswari P, Madhu K. Synthesis and in vitro antitubercular activity of some 1-[(4-sub)phenyl]-3-(4-{1-[(pyridine-4-carbonyl)hydrazono]ethyl}phenyl) thiourea. Bioorg Med Chem Lett, 16: 876-878, 2006.
    • (2006) Bioorg Med Chem Lett , vol.16 , pp. 876-878
    • Sriram, D.1    Yogeeswari, P.2    Madhu, K.3
  • 7
    • 34548385246 scopus 로고    scopus 로고
    • Biological Activities of Hydrazone Derivatives
    • Rollas S, Küçükgüzel ŞG. Biological Activities of Hydrazone Derivatives. Molecules, 12:1910-1939, 2007.
    • (2007) Molecules , vol.12 , pp. 1910-1939
    • Rollas, S.1    Küçükgüzel, S.G.2
  • 9
    • 34447542173 scopus 로고    scopus 로고
    • Antimycobacterial activity of novel 1-(5-cyclobutyl-1,3-oxazol-2-yl)-3-(sub)phenyl/pyridylthiourea compounds endowed with high activity toward multidrug-resistant Mycobacterium tuberculosis
    • Sriram D, Yogeeswari P, Dinakaran M, Thirumurugan R. Antimycobacterial activity of novel 1-(5-cyclobutyl-1,3-oxazol-2-yl)-3-(sub)phenyl/pyridylthiourea compounds endowed with high activity toward multidrug-resistant Mycobacterium tuberculosis. J Antimicrob Chem, 59: 1194-1196, 2007.
    • (2007) J Antimicrob Chem , vol.59 , pp. 1194-1196
    • Sriram, D.1    Yogeeswari, P.2    Dinakaran, M.3    Thirumurugan, R.4
  • 10
    • 33751032349 scopus 로고    scopus 로고
    • Synthesis and characterization of novel hydrazide-hydrazones and the study of their structure-antituberculosis activity
    • Kaymakçi{dotless}oǧlu BK, Oruç EE, Ünsalan S, Kandemirli F, Shvets N, Rollas S, Anatholy D. Synthesis and characterization of novel hydrazide-hydrazones and the study of their structure-antituberculosis activity. Eur J Med Chem, 41:1253-1261, 2006.
    • (2006) Eur J Med Chem , vol.41 , pp. 1253-1261
    • Kaymakçioǧlu, B.K.1    Oruç, E.E.2    Ünsalan, S.3    Kandemirli, F.4    Shvets, N.5    Rollas, S.6    Anatholy, D.7
  • 11
    • 33646500347 scopus 로고    scopus 로고
    • Synthesis of 1-[3-(4-benzotriazol-1/2-yl-3-fluoro-phenyl)-2-oxo-oxazolidin-5-ylmethyl ]-3-substituted thiourea derivatives as antituberculosis agents
    • Dixit PP, Patil VJ, Nair PS, Jain S, Sinha N, Arora SK. Synthesis of 1-[3-(4-benzotriazol-1/2-yl-3-fluoro-phenyl)-2-oxo-oxazolidin-5-ylmethyl ]-3-substituted thiourea derivatives as antituberculosis agents. Eur J Med Chem, 41: 423-428, 2006.
    • (2006) Eur J Med Chem , vol.41 , pp. 423-428
    • Dixit, P.P.1    Patil, V.J.2    Nair, P.S.3    Jain, S.4    Sinha, N.5    Arora, S.K.6
  • 12
    • 38949167100 scopus 로고    scopus 로고
    • Quantitative structure activity relationship studies on thiourea analogues as influenza virus neuraminidase inhibitors
    • Nair PC, Sobhia ME. Quantitative structure activity relationship studies on thiourea analogues as influenza virus neuraminidase inhibitors. Eur J Med Chem, 43: 293-299, 2008.
    • (2008) Eur J Med Chem , vol.43 , pp. 293-299
    • Nair, P.C.1    Sobhia, M.E.2
  • 13
    • 38949189604 scopus 로고    scopus 로고
    • Synthesis of Some novel thiourea derivatives obtained from 5-[(4-aminophenoxy)methyl]-4-methyl-2,4-dihydro-3H-1,2,4-triazole-3-thio nes and evaluation as antiviral / anti-HIV agents
    • Küçükgüzel İ, Tatar E, Küçükgüzel ŞG, Rollas S, De Clercq E. Synthesis of Some novel thiourea derivatives obtained from 5-[(4-aminophenoxy)methyl]-4-methyl-2,4-dihydro-3H-1,2,4-triazole-3-thio nes and evaluation as antiviral / anti-HIV agents. Eur J Med Chem, 43: 381-392, 2008.
    • (2008) Eur J Med Chem , vol.43 , pp. 381-392
    • Küçükgüzel, I.1    Tatar, E.2    Küçükgüzel, S.G.3    Rollas, S.4    de Clercq, E.5
  • 14
    • 0342514570 scopus 로고    scopus 로고
    • Synthesis and Antimycobacterial activity of some coupling products from 4-aminobenzoic acid hydrazones
    • Küçükgüzel ŞG, Rollas S, Küçükgüzel İ, Kiraz M. Synthesis and Antimycobacterial activity of some coupling products from 4-aminobenzoic acid hydrazones. Eur J Med Chem, 34: 1093-1100, 1999.
    • (1999) Eur J Med Chem , vol.34 , pp. 1093-1100
    • Küçükgüzel, S.G.1    Rollas, S.2    Küçükgüzel, I.3    Kiraz, M.4
  • 15
    • 0035833072 scopus 로고    scopus 로고
    • Some 3-thioxo / alkylthio-1,2,4-triazoles with a substituted thiourea moiety as possible antimycobacterials
    • Küçükgüzel İ, Küçükgüzel ŞG, Rollas S, Kiraz M. Some 3-thioxo / alkylthio-1,2,4-triazoles with a substituted thiourea moiety as possible antimycobacterials. Bioorg Med Chem Lett, 11: 1703-1707, 2001.
    • (2001) Bioorg Med Chem Lett , vol.11 , pp. 1703-1707
    • Küçükgüzel, I.1    Küçükgüzel, S.G.2    Rollas, S.3    Kiraz, M.4
  • 16
    • 0037019130 scopus 로고    scopus 로고
    • Synthesis and antituberculosis activity of new N-phenyl-N'-[4-(5-alkyl/arylamino-1,3,4-thiadiazole-2-yl)phenyl]thiourea s
    • Karakuş S, Rollas S. Synthesis and antituberculosis activity of new N-phenyl-N'-[4-(5-alkyl/arylamino-1,3,4-thiadiazole-2-yl)phenyl]thiourea s. Farmaco, 57: 577-581, 2002.
    • (2002) Farmaco , vol.57 , pp. 577-581
    • Karakuş, S.1    Rollas, S.2
  • 17
    • 0029548497 scopus 로고
    • Evaluation of some arylhydrazones of p-Aminobenzoic acid hydrazide as antimicrobial agents and their in-vitro hepatic microsomal metabolism
    • Kömürcü ŞG, Rollas S, Ülgen M, Gorrod JW, Çevikbaş A. Evaluation of some arylhydrazones of p-Aminobenzoic acid hydrazide as antimicrobial agents and their in-vitro hepatic microsomal metabolism. Boll Chim Farmaceutico, 134: 375-379, 1995.
    • (1995) Boll Chim Farmaceutico , vol.134 , pp. 375-379
    • Kömürcü, S.G.1    Rollas, S.2    Ülgen, M.3    Gorrod, J.W.4    Çevikbaş, A.5
  • 18
    • 0026036259 scopus 로고
    • N-[4-(3H-1,3,4-oxadiazoline-2-thion-5-yl)phenyl]-N'-substituted thioureas: Synthesis and antimicrobiological activities
    • Rollas S, Büyüktimkin S, Çevikbaş A. N-[4-(3H-1,3,4-oxadiazoline-2-thion-5-yl)phenyl]-N'-substituted thioureas: synthesis and antimicrobiological activities. Arch Pharm (Weinheim), 324:189-190, 1991.
    • (1991) Arch Pharm (Weinheim) , vol.324 , pp. 189-190
    • Rollas, S.1    Büyüktimkin, S.2    Çevikbaş, A.3
  • 21
    • 23244468299 scopus 로고    scopus 로고
    • Synthesis and biological evaluation of new N-substituted-N'-(3,5-di/1,3,5-trimethylpyrazole-4-yl)thiourea/ urea derivatives
    • Koçyiǧit-Kaymakçi{dotless}oǧlu B, Rollas S, Körceǧiz E, Ari{dotless}ci{dotless}oǧlu F. Synthesis and biological evaluation of new N-substituted-N'-(3,5-di/1,3,5-trimethylpyrazole-4-yl)thiourea/ urea derivatives. Eur J Pharm Sci, 26: 97-103, 2005.
    • (2005) Eur J Pharm Sci , vol.26 , pp. 97-103
    • Koçyiǧit-Kaymakçioǧlu, B.1    Rollas, S.2    Körceǧiz, E.3    Aricioǧlu, F.4
  • 24
    • 0021237243 scopus 로고
    • Detection, isolation, and continuous production of cytopathic retroviruses (HTLV-III) from patients with AIDS and pre-AIDS
    • Popovic M, Sarngadharan MG, Read E, Gallo RC. Detection, isolation, and continuous production of cytopathic retroviruses (HTLV-III) from patients with AIDS and pre-AIDS. Science, 224: 497-500, 1984.
    • (1984) Science , vol.224 , pp. 497-500
    • Popovic, M.1    Sarngadharan, M.G.2    Read, E.3    Gallo, R.C.4
  • 28
    • 85080468944 scopus 로고    scopus 로고
    • http://www.taacf.org/about-TAACF.htm
  • 29
    • 0030903133 scopus 로고    scopus 로고
    • Microplate alamar blue assay versus BACTEC 460 system for high-throughput screening of compounds against Mycobacterium tuberculosis and Mycobacterium avium
    • Collins L, Franzblau G. Microplate alamar blue assay versus BACTEC 460 system for high-throughput screening of compounds against Mycobacterium tuberculosis and Mycobacterium avium. Antimicrob Agents Chemother, 41:1004-1009, 1997.
    • (1997) Antimicrob Agents Chemother , vol.41 , pp. 1004-1009
    • Collins, L.1    Franzblau, G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.