Antimycobacterial activity of novel 1-(5-cyclobutyl-1,3-oxazol-2-yl)-3-(sub)phenyl/pyridylthiourea compounds endowed with high activity toward multidrug-resistant Mycobacterium tuberculosis

Journal of Antimicrobial Chemotherapy

Volumn 59, Issue 6, 2007, Pages 1194-1196

  Sriram, Dharmarajan ^a   Yogeeswari, Perumal ^a   Dinakaran, Murugesan ^a   Thirumurugan, Rathinasababathy ^a  

^a BIRLA INSTITUTE OF TECHNOLOGY AND SCIENCE   (India)

Author keywords

Antimycobacterial activity; Antitubercular activity; Oxazole derivatives; Thiourea derivatives

Indexed keywords

1 (5 CYCLOBUTYL 1,3 OXAZOL 2 YL) 3 (2' TRIFLUOROMETHYL)PHENYLTHIOUREA; 1 (5 CYCLOBUTYL 1,3 OXAZOL 2 YL) 3 PHENYLTHIOUREA DERIVATIVE; 1 (5 CYCLOBUTYL 1,3 OXAZOL 2 YL) 3 PYRIDYLTHIOUREA DERIVATIVE; AMINE; ANILINE DERIVATIVE; ETHAMBUTOL; GATIFLOXACIN; IMIDAZOLE DERIVATIVE; ISONIAZID; PHENYLTHIOUREA; PYRIDINE DERIVATIVE; RIFAMPICIN; UNCLASSIFIED DRUG;

ANIMAL MODEL; ANIMAL TISSUE; ANTIBACTERIAL ACTIVITY; ARTICLE; CHEMICAL REACTION; CONTROLLED STUDY; DRUG STRUCTURE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LUNG PARENCHYMA; MINIMUM INHIBITORY CONCENTRATION; MOUSE; MULTIDRUG RESISTANCE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; SPLEEN; TUBERCULOSIS; VERO CELL;

ANIMALS; ANTITUBERCULAR AGENTS; CELL SURVIVAL; CERCOPITHECUS AETHIOPS; DRUG RESISTANCE, MULTIPLE, BACTERIAL; FEMALE; ISONIAZID; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MICROBIAL SENSITIVITY TESTS; MYCOBACTERIUM TUBERCULOSIS; PYRIDINES; STRUCTURE-ACTIVITY RELATIONSHIP; TETRAZOLIUM SALTS; THIAZOLES; THIOUREA; TUBERCULOSIS; VERO CELLS;

EID: 34447542173     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dkm085     Document Type: Article

References (5)

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