Exploration of 2, 4-diaminopyrimidine and 2, 4-diamino-s-triazine derivatives as potential antifilarial agents

Parasitology

Volumn 140, Issue 8, 2013, Pages 959-965

  Sharma, R D ^a   Bag, S ^b   Tawari, N R ^b   Degani, M S ^b   Goswami, K ^a   Reddy, M V R ^a  

^a MAHATMA GANDHI INSTITUTE OF MEDICAL SCIENCES   (India)

^b INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

Author keywords

2,4 diamino s triazine; 2,4 diaminopyrimidine; antifilarial; Brugia malayi; DHFR; filariasis

Indexed keywords

2,4 DIAMINOPYRIMIDINE DERIVATIVE; ACRIDINE ORANGE; ANTIFILARIAL AGENT; DIHYDROFOLATE REDUCTASE; ETHIDIUM BROMIDE; FOLIC ACID; FOLINIC ACID; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; STAUROSPORINE; TRIAZINE DERIVATIVE;

ANTIMICROBIAL ACTIVITY; APOPTOSIS; ARTICLE; BRUGIA MALAYI; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; DRUG SCREENING; DRUG STRUCTURE; DRUG WITHDRAWAL; ENZYME INHIBITION; FILARIASIS; IC 50; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL;

AEDES; ANIMALS; BRUGIA MALAYI; ELEPHANTIASIS, FILARIAL; FEMALE; FILARICIDES; FOLIC ACID ANTAGONISTS; GERBILLINAE; HELMINTH PROTEINS; HUMANS; INHIBITORY CONCENTRATION 50; MALE; MICROFILARIA; MURINAE; PARASITIC SENSITIVITY TESTS; PYRIMIDINES; TETRAHYDROFOLATE DEHYDROGENASE; TRIAZINES;

BRUGIA MALAYI;

EID: 84878836212     PISSN: 00311820     EISSN: 14698161     Source Type: Journal    
DOI: 10.1017/S0031182013000309     Document Type: Article

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