The candidate tumor suppressor gene Ecrg4 as a wound terminating factor in cutaneous injury

Archives of Dermatological Research

Volumn 305, Issue 2, 2013, Pages 141-149

  Shaterian, Ashkaun ^a   Kao, Steven ^a   Chen, Lin ^b   Dipietro, Luisa A ^b   Coimbra, Raul ^a   Eliceiri, Brian P ^a   Baird, Andrew ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

Ecrg4; Skin; Tumor suppressor gene; Wound closure; Wound healing

Indexed keywords

ESOPHAGEAL CANCER RELATED GENE 4 PROTEIN; MESSENGER RNA; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EMBRYO; ESOPHAGEAL CANCER RELATED GENE 4; GENE EXPRESSION; GENE LOCATION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; IN VITRO STUDY; IN VIVO STUDY; MICROARRAY ANALYSIS; MIGRATION INHIBITION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SKIN FIBROBLAST; SKIN INJURY; TUMOR SUPPRESSOR GENE;

ANIMALS; CELL MOVEMENT; CELLS, CULTURED; DISEASE MODELS, ANIMAL; FIBROBLASTS; GENES, TUMOR SUPPRESSOR; GENETIC VECTORS; HUMANS; MICE; MICE, INBRED BALB C; NEOPLASM PROTEINS; SKIN; TRANSGENES; WOUND HEALING;

EID: 84878823266     PISSN: 03403696     EISSN: 1432069X     Source Type: Journal    
DOI: 10.1007/s00403-012-1276-7     Document Type: Article

References (40)

1. Baird A, Coimbra R, Dang X, Lopez N, Lee J, Krzyzaniak M, Winfield R, Potenza B, Eliceiri BP (2012) Cell surface localization and release of the candidate tumor suppressor Ecrg4 from polymorphonuclear cells and monocytes activate macrophages. J Leukoc Biol 91(5):773-781
2. Bartkova J, Gron B, Dabelsteen E, Bartek J (2003) Cell-cycle regulatory proteins in human wound healing. Arch Oral Biol 48(2):125-132
3. Baum CL, Arpey CJ (2005) Normal cutaneous wound healing: clinical correlation with cellular and molecular events. Dermatol Surg 31(6):674-686 (discussion 686)
4. Chen L, Arbieva ZH, Guo S, Marucha PT, Mustoe TA, DiPietro LA (2010) Positional differences in the wound transcriptome of skin and oral mucosa. BMC Genom 11:471
5. Croce CM (2008) Oncogenes and cancer. N Engl J Med 358(5):502-511
6. Demaria M, Misale S, Giorgi C, Miano V, Camporeale A, Campisi J, Pinton P, Poli V (2012) STAT3 can serve as a hit in the process of malignant transformation of primary cells. Cell Death Differ. doi: 10.1038/cdd.2012.20
7. Deonarine K, Panelli MC, Stashower ME, Jin P, Smith K, Slade HB, Norwood C, Wang E, Marincola FM, Stroncek DF (2007) Gene expression profiling of cutaneous wound healing. J Transl Med 5:11
8. Doshi BM, Perdrizet GA, Hightower LE (2008) Wound healing from a cellular stress response perspective. Cell Stress Chaperones 13(4):393-399
9. Dvorak HF (1986) Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing. N Engl J Med 315(26):1650-1659
10. Eliceiri BP, Klemke R, Stromblad S, Cheresh DA (1998) Integrin alphavbeta3 requirement for sustained mitogen-activated protein kinase activity during angiogenesis. J Cell Biol 140(5):1255-1263
11. Gannon HS, Donehower LA, Lyle S, Jones SN (2011) Mdm2-p53 signaling regulates epidermal stem cell senescence and premature aging phenotypes in mouse skin. Dev Biol 353(1):1-9
12. Gonzalez AM, Podvin S, Lin SY, Miller MC, Botfield H, Leadbeater WE, Roberton A, Dang X, Knowling SE, Cardenas-Galindo E, Donahue JE, Stopa EG, Johanson CE, Coimbra R, Eliceiri BP, Baird A (2011) Ecrg4 expression and its product augurin in the choroid plexus: impact on fetal brain development, cerebrospinal fluid homeostasis and neuroprogenitor cell response to CNS injury. Fluids Barriers CNS 8(1):6
13. Gotze S, Feldhaus V, Traska T, Wolter M, Reifenberger G, Tannapfel A, Kuhnen C, Martin D, Muller O, Sievers S (2009) ECRG4 is a candidate tumor suppressor gene frequently hypermethylated in colorectal carcinoma and glioma. BMC Cancer 9:447
14. Guo S, Dipietro LA (2010) Factors affecting wound healing. J Dent Res 89(3):219-229
15. Gurtner GC, Werner S, Barrandon Y, Longaker MT (2008) Wound repair and regeneration. Nature 453(7193):314-321
16. Kamiya K, Ryer E, Sakakibara K, Zohlman A, Kent KC, Liu B (2007) Protein kinase C delta activated adhesion regulates vascular smooth muscle cell migration. J Surg Res 141(1):91-96
17. Kane CD, Greenhalgh DG (2000) Expression and localization of p53 and bcl-2 in healing wounds in diabetic and nondiabetic mice. Wound Repair Regen 8(1):45-58
18. King KE, Weinberg WC (2007) p63: defining roles in morphogenesis, homeostasis, and neoplasia of the epidermis. Mol Carcinog 46(8):716-724
19. Li L, Zhang C, Li X, Lu S, Zhou Y (2010) The candidate tumor suppressor gene ECRG4 inhibits cancer cells migration and invasion in esophageal carcinoma. J Exp Clin Cancer Res 29:133
20. Li W, Liu X, Zhang B, Qi D, Zhang L, Jin Y, Yang H (2010) Overexpression of candidate tumor suppressor ECRG4 inhibits glioma proliferation and invasion. J Exp Clin Cancer Res 29:89
21. Li X, Mohan S, Gu W, Baylink DJ (2001) Analysis of gene expression in the wound repair/regeneration process. Mamm Genome 12(1):52-59
22. Lindblad WJ (2004) The future of human wound repair-regeneration science. Wound Repair Regen 12(3):261
23. Martin P (1997) Wound healing - aiming for perfect skin regeneration. Science 276(5309):75-81
24. Mirabeau O, Perlas E, Severini C, Audero E, Gascuel O, Possenti R, Birney E, Rosenthal N, Gross C (2007) Identification of novel peptide hormones in the human proteome by hidden Markov model screening. Genome Res 17(3):320-327
25. Mori Y, Ishiguro H, Kuwabara Y, Kimura M, Mitsui A, Kurehara H, Mori R, Tomoda K, Ogawa R, Katada T, Harata K, Fujii Y (2007) Expression of ECRG4 is an independent prognostic factor for poor survival in patients with esophageal squamous cell carcinoma. Oncol Rep 18(4):981-985
26. O'Grady NP, Tropea M, Preas HL 2nd, Reda D, Vandivier RW, Banks SM, Suffredini AF (1999) Detection of macrophage inflammatory protein (MIP)-1alpha and MIP-1beta during experimental endotoxemia and human sepsis. J Infect Dis 179(1):136-141
27. Ozawa A, Lick AN, Lindberg I (2011) Processing of proaugurin is required to suppress proliferation of tumor cell lines. Mol Endocrinol 25(5):776-784
28. Peterson CY, Shaterian A, Borboa AK, Gonzalez AM, Potenza BM, Coimbra R, Eliceiri BP, Baird A (2009) The noninvasive, quantitative, in vivo assessment of adenoviral-mediated gene delivery in skin wound biomaterials. Biomaterials 30(35):6788-6793
29. Podvin S, Gonzalez AM, Miller MC, Dang X, Botfield H, Donahue JE, Kurabi A, Boissaud-Cooke M, Rossi R, Leadbeater WE, Johanson CE, Coimbra R, Stopa EG, Eliceiri BP, Baird A (2011) Esophageal cancer related gene-4 is a choroid plexus-derived injury response gene: evidence for a biphasic response in early and late brain injury. PLoS ONE 6(9):e24609
30. Riss J, Khanna C, Koo S, Chandramouli GV, Yang HH, Hu Y, Kleiner DE, Rosenwald A, Schaefer CF, Ben-Sasson SA, Yang L, Powell J, Kane DW, Star RA, Aprelikova O, Bauer K, Vasselli JR, Maranchie JK, Kohn KW, Buetow KH, Linehan WM, Weinstein JN, Lee MP, Klausner RD, Barrett JC (2006) Cancers as wounds that do not heal: differences and similarities between renal regeneration/repair and renal cell carcinoma. Cancer Res 66(14):7216-7224
31. Schafer M, Werner S (2007) Transcriptional control of wound repair. Annu Rev Cell Dev Biol 23:69-92
32. Schafer M, Werner S (2008) Cancer as an overhealing wound: an old hypothesis revisited. Nat Rev Mol Cell Biol 9(8):628-638
33. Shaterian A, Borboa A, Sawada R, Costantini T, Potenza B, Coimbra R, Baird A, Eliceiri BP (2009) Real-time analysis of the kinetics of angiogenesis and vascular permeability in an animal model of wound healing. Burns 35(6):811-817
34. Shaw TJ, Martin P (2009) Wound repair at a glance. J Cell Sci 122(Pt 18):3209-3213
35. Stadelmann WK, Digenis AG, Tobin GR (1998) Physiology and healing dynamics of chronic cutaneous wounds. Am J Surg 176(2A suppl):26S-38S
36. Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci USA 99(26):16899-16903
37. Streit M, Velasco P, Riccardi L, Spencer L, Brown LF, Janes L, Lange-Asschenfeldt B, Yano K, Hawighorst T, Iruela-Arispe L, Detmar M (2000) Thrombospondin-1 suppresses wound healing and granulation tissue formation in the skin of transgenic mice. EMBO J 19(13):3272-3282
38. Tan SH, Pal M, Tan MJ, Wong MH, Tam FU, Teo JW, Chong HC, Tan CK, Goh YY, Tang MB, Cheung PC, Tan NS (2009) Regulation of cell proliferation and migration by TAK1 via transcriptional control of von Hippel-Lindau tumor suppressor. J Biol Chem 284(27):18047-18058
39. Werner S, Grose R (2003) Regulation of wound healing by growth factors and cytokines. Physiol Rev 83(3):835-870
40. Yue CM, Deng DJ, Bi MX, Guo LP, Lu SH (2003) Expression of ECRG4, a novel esophageal cancer-related gene, downregulated by CpG island hypermethylation in human esophageal squamous cell carcinoma. World J Gastroenterol 9(6):1174-1178