Evaluating Baculovirus as a Vector for Human Prostate Cancer Gene Therapy

PLoS ONE

Volumn 8, Issue 6, 2013, Pages

  Swift, Stephanie L ^a   Rivera, Guillermo C ^a   Dussupt, Vincent ^a   Leadley, Regina M ^a   Hudson, Lucy C ^a   MA de Ridder, Corrina ^b   Kraaij, Robert ^b   Burns, Julie E ^a   Maitland, Norman J ^a   Georgopoulos, Lindsay J ^a  

^a UNIVERSITY OF YORK   (United Kingdom)

^b ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

BACULOVIRUS VECTOR; ENHANCED GREEN FLUORESCENT PROTEIN; NITROREDUCTASE; PRODRUG; TRETAZICAR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL CULTURE; CANCER GENE THERAPY; CANCER STAGING; CELL DIFFERENTIATION; CELL TYPE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOMEGALOVIRUS; DRUG MECHANISM; EPITHELIUM CELL; FEMALE; GENE DIRECTED ENZYME PRODRUG THERAPY; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PHENOTYPE; PROSTATE CANCER; STROMA CELL; TRANSGENE; TUMOR SPHEROID; TUMOR XENOGRAFT; VIRAL GENE DELIVERY SYSTEM; ANIMAL; BACULOVIRIDAE; CELL LINE; CELL SURVIVAL; CONFOCAL MICROSCOPY; DRUG SCREENING; FLOW CYTOMETRY; GENE THERAPY; GENE VECTOR; GENETICS; NUDE MOUSE; PHYSIOLOGY; PROCEDURES; PROSTATIC NEOPLASMS; TUMOR CELL CULTURE; TUMOR CELL LINE;

HEXAPODA; MURINAE;

ANIMALS; BACULOVIRIDAE; CELL LINE; CELL LINE, TUMOR; CELL SURVIVAL; FLOW CYTOMETRY; GENETIC THERAPY; GENETIC VECTORS; HUMANS; MALE; MICE; MICE, NUDE; MICROSCOPY, CONFOCAL; PROSTATIC NEOPLASMS; TUMOR CELLS, CULTURED; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84878776778     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0065557     Document Type: Article

References (60)

1. Cunha GR, Ricke W, Thomson A, Marker PC, Risbridger G, et al. (2004) Hormonal, cellular, and molecular regulation of normal and neoplastic prostatic development. J Steroid Biochem Mol Biol 92: 221-236.
2. El-Alfy M, Pelletier G, Hermo LS, Labrie F, (2000) Unique features of the basal cells of human prostate epithelium. Microsc Res Tech 51: 436-446.
3. Abate-Shen C, Shen MM, (2000) Molecular genetics of prostate cancer. Genes Dev 14: 2410-2434.
4. Maitland NJ, Stanbridge LJ, Dussupt V, (2004) Targeting gene therapy for prostate cancer. Curr Pharm Des 10: 531-555.
5. Carson DD, Summers MD, Guarino LA, (1991) Transient expression of the Autographa californica nuclear polyhedrosis virus immediate-early gene, IE-N, is regulated by three viral elements. J Virol 65: 945-951.
6. Volkman LE, Goldsmith PA, (1983) In Vitro Survey of Autographa californica Nuclear Polyhedrosis Virus Interaction with Nontarget Vertebrate Host Cells. Appl Environ Microbiol 45: 1085-1093.
7. van Loo ND, Fortunati E, Ehlert E, Rabelink M, Grosveld F, et al. (2001) Baculovirus infection of nondividing mammalian cells: mechanisms of entry and nuclear transport of capsids. J Virol 75: 961-970.
8. Gao R, McCormick CJ, Arthur MJ, Ruddell R, Oakley F, et al. (2002) High efficiency gene transfer into cultured primary rat and human hepatic stellate cells using baculovirus vectors. Liver 22: 15-22.
9. Zeng J, Du J, Zhao Y, Palanisamy N, Wang S, (2007) Baculoviral vector-mediated transient and stable transgene expression in human embryonic stem cells. Stem Cells 25: 1055-1061.
10. Burges HD, Croizier G, Huber J, (1980) A review of safety tests on baculoviruses. BioControl 25: 329-339.
11. Hofmann C, Sandig V, Jennings G, Rudolph M, Schlag P, et al. (1995) Efficient gene transfer into human hepatocytes by baculovirus vectors. Proc Natl Acad Sci U S A 92: 10099-10103.
12. Sarkis C, Serguera C, Petres S, Buchet D, Ridet JL, et al. (2000) Efficient transduction of neural cells in vitro and in vivo by a baculovirus-derived vector. Proc Natl Acad Sci U S A 97: 14638-14643.
13. Ho YC, Lee HP, Hwang SM, Lo WH, Chen HC, et al. (2006) Baculovirus transduction of human mesenchymal stem cell-derived progenitor cells: variation of transgene expression with cellular differentiation states. Gene Ther 13: 1471-1479.
14. Sandig V, Hofmann C, Steinert S, Jennings G, Schlag P, et al. (1996) Gene transfer into hepatocytes and human liver tissue by baculovirus vectors. 7: 1937-1945.
15. Georgopoulos LJ, Elgue G, Sanchez J, Dussupt V, Magotti P, et al. (2009) Preclinical evaluation of innate immunity to baculovirus gene therapy vectors in whole human blood. 46: 2911-2917.
16. Hofmann C, Strauss M, (1998) Baculovirus-mediated gene transfer in the presence of human serum or blood facilitated by inhibition of the complement system. 5: 531-536.
17. Kaikkonen MU, Maatta AI, Yla-Herttuala S, Airenne KJ, (2010) Screening of complement inhibitors: shielded baculoviruses increase the safety and efficacy of gene delivery. 18: 987-992.
18. Huser A, Rudolph M, Hofmann C, (2001) Incorporation of decay-accelerating factor into the baculovirus envelope generates complement-resistant gene transfer vectors. 19: 451-455.
19. Kaname Y, Tani H, Kataoka C, Shiokawa M, Taguwa S, et al. (2010) Acquisition of complement resistance through incorporation of CD55/decay-accelerating factor into viral particles bearing baculovirus GP64. 84: 3210-3219.
20. Kinnunen K, Kalesnykas G, Mahonen AJ, Laidinen S, Holma L, et al. (2009) Baculovirus is an efficient vector for the transduction of the eye: comparison of baculovirus- and adenovirus-mediated intravitreal vascular endothelial growth factor D gene transfer in the rabbit eye. 11: 382-389.
21. Lehtolainen P, Tyynela K, Kannasto J, Airenne KJ, Yla-Herttuala S, (2002) Baculoviruses exhibit restricted cell type specificity in rat brain: a comparison of baculovirus- and adenovirus-mediated intracerebral gene transfer in vivo. Gene Ther 9: 1693-1699.
22. Li Y, Wang X, Guo H, Wang S, (2004) Axonal transport of recombinant baculovirus vectors. Mol Ther 10: 1121-1129.
23. Tani H, Limn CK, Yap CC, Onishi M, Nozaki M, et al. (2003) In vitro and in vivo gene delivery by recombinant baculoviruses. J Virol 77: 9799-9808.
24. Huang W, Tian XL, Wu YL, Zhong J, Yu LF, et al. (2008) Suppression of gastric cancer growth by baculovirus vector-mediated transfer of normal epithelial cell specific-1 gene. 14: 5810-5815.
25. Marques RB, van Weerden WM, Erkens-Schulze S, de Ridder CM, Bangma CH, et al. (2006) The human PC346 xenograft and cell line panel: a model system for prostate cancer progression. Eur Urol 49: 245-257.
26. Berthon P, Cussenot O, Hopwood L, Leduc A, Maitland N, (1995) Functional expression of sv40 in normal human prostatic epithelial and fibroblastic cells- differentiation pattern of nontumorigenic cell-lines. Int J Oncol 6: 333-343.
27. Maitland NJ, Macintosh CA, Hall J, Sharrard M, Quinn G, et al. (2001) In vitro models to study cellular differentiation and function in human prostate cancers. Radiat Res 155: 133-142.
28. Swift SL, Burns JE, Maitland NJ, (2010) Altered expression of neurotensin receptors is associated with the differentiation state of prostate cancer. Cancer Res 70: 347-356.
29. Collins AT, Habib FK, Maitland NJ, Neal DE, (2001) Identification and isolation of human prostate epithelial stem cells based on alpha(2)beta(1)-integrin expression. J Cell Sci 114: 3865-3872.
30. Knudson DL, Tinsley TW, (1974) Replication of a nuclear polyhedrosis virus in a continuous cell culture of Spodoptera frugiperda: purification, assay of infectivity, and growth characteristics of the virus. J Virol 14: 934-944.
31. Volkman LE, Summers MD, Hsieh CH, (1976) Occluded and nonoccluded nuclear polyhedrosis virus grown in Trichoplusia ni: comparative neutralization comparative infectivity, and in vitro growth studies. J Virol 19: 820-832.
32. Wang X, Kelly DC, (1985) Baculovirus Replication: Uptake of Trichoplusia ni Nuclear Polyhedrosis Virus Particles by Insect Cells. J Gen Virol 66: 541-550.
33. Whitt MA, Manning JS, (1988) A phosphorylated 34-kDa protein and a subpopulation of polyhedrin are thiol linked to the carbohydrate layer surrounding a baculovirus occlusion body. Virology 163: 33-42.
34. Rembrink K, Romijn JC, van der Kwast TH, Rubben H, Schroder FH, (1997) Orthotopic implantation of human prostate cancer cell lines: a clinically relevant animal model for metastatic prostate cancer. Prostate 31: 168-174.
35. Kraaij R, van Weerden WM, de Ridder CM, Gussenhoven EJ, Honkoop J, et al. (2002) Validation of transrectal ultrasonographic volumetry for orthotopic prostate tumours in mice. Lab Anim 36: 165-172.
36. Airenne KJ, Makkonen KE, Mahonen AJ, Yla-Herttuala S, (2010) In vivo application and tracking of baculovirus. Curr Gene Ther 10: 187-194.
37. Lang SH, Stower M, Maitland NJ, (2000) In vitro modelling of epithelial and stromal interactions in non-malignant and malignant prostates. Br J Cancer 82: 990-997.
38. van Leenders G, Dijkman H, Hulsbergen-van de Kaa C, Ruiter D, Schalken J, (2000) Demonstration of intermediate cells during human prostate epithelial differentiation in situ and in vitro using triple-staining confocal scanning microscopy. Lab Invest 80: 1251-1258.
39. Cunha GR, Wang YZ, Hayward SW, Risbridger GP, (2001) Estrogenic effects on prostatic differentiation and carcinogenesis. Reprod Fertil Dev 13: 285-296.
40. Olumi AF, Grossfeld GD, Hayward SW, Carroll PR, Tlsty TD, et al. (1999) Carcinoma-associated fibroblasts direct tumor progression of initiated human prostatic epithelium. Cancer Res 59: 5002-5011.
41. Searle PF, Chen MJ, Hu L, Race PR, Lovering AL, et al. (2004) Nitroreductase: a prodrug-activating enzyme for cancer gene therapy. Clin Exp Pharmacol Physiol 31: 811-816.
42. Horoszewicz JS, Leong SS, Chu TM, Wajsman ZL, Friedman M, et al. (1980) The LNCaP cell line-a new model for studies on human prostatic carcinoma. Prog Clin Biol Res 37: 115-132.
43. Kaighn ME, Narayan KS, Ohnuki Y, Lechner JF, Jones LW, (1979) Establishment and characterization of a human prostatic carcinoma cell line (PC-3). Invest Urol 17: 16-23.
44. Datta MW, Hernandez AM, Schlicht MJ, Kahler AJ, DeGueme AM, et al. (2006) Perlecan, a candidate gene for the CAPB locus, regulates prostate cancer cell growth via the Sonic Hedgehog pathway. Mol Cancer 5: 9.
45. Shariat SF, Svatek RS, Kabbani W, Walz J, Lotan Y, et al. (2008) Prognostic value of syndecan-1 expression in patients treated with radical prostatectomy. BJU Int 101: 232-237.
46. Duisit G, Saleun S, Douthe S, Barsoum J, Chadeuf G, et al. (1999) Baculovirus vector requires electrostatic interactions including heparan sulfate for efficient gene transfer in mammalian cells. J Gene Med 1: 93-102.
47. Maitland N, Chambers K, Georgopoulos L, Simpson-Holley M, Leadley R, et al. (2010) Gene transfer vectors targeted to human prostate cancer: do we need better preclinical testing systems? Hum Gene Ther 21: 815-827.
48. Batra RK, Olsen JC, Pickles RJ, Hoganson DK, Boucher RC, (1998) Transduction of non-small cell lung cancer cells by adenoviral and retroviral vectors. Am J Respir Cell Mol Biol 18: 402-410.
49. Russell DW, Miller AD, Alexander IE, (1994) Adeno-associated virus vectors preferentially transduce cells in S phase. Proc Natl Acad Sci U S A 91: 8915-8919.
50. Zack JA, (1995) The role of the cell cycle in HIV-1 infection. Adv Exp Med Biol 374: 27-31.
51. De Klerk DP, (1983) The glycosaminoglycans of normal and hyperplastic prostate. Prostate 4: 73-81.
52. De Klerk DP, Lee DV, Human HJ, (1984) Glycosaminoglycans of human prostatic cancer. J Urol 131: 1008-1012.
53. Washburn JO, Chan EY, Volkman LE, Aumiller JJ, Jarvis DL, (2003) Early synthesis of budded virus envelope fusion protein GP64 enhances Autographa californica multicapsid nucleopolyhedrovirus virulence in orally infected Heliothis virescens. J Virol 77: 280-290.
54. Washburn JO, Lyons EH, Haas-Stapleton EJ, Volkman LE, (1999) Multiple nucleocapsid packaging of Autographa californica nucleopolyhedrovirus accelerates the onset of systemic infection in Trichoplusia ni. J Virol 73: 411-416.
55. Vicente T, Peixoto C, Carrondo MJ, Alves PM, (2009) Purification of recombinant baculoviruses for gene therapy using membrane processes. Gene Ther 16: 766-775.
56. Djeha AH, Hulme A, Dexter MT, Mountain A, Young LS, et al. (2000) Expression of Escherichia coli B nitroreductase in established human tumor xenografts in mice results in potent antitumoral and bystander effects upon systemic administration of the prodrug CB1954. Cancer Gene Ther 7: 721-731.
57. Blackwood L, O'Shaughnessy PJ, Reid SW, Argyle DJ, (2001) E. coli nitroreductase/CB1954: in vitro studies into a potential system for feline cancer gene therapy. Vet J 161: 269-279.
58. Bridgewater JA, Knox RJ, Pitts JD, Collins MK, Springer CJ, (1997) The bystander effect of the nitroreductase/CB1954 enzyme/prodrug system is due to a cell-permeable metabolite. Hum Gene Ther 8: 709-717.
59. Wilson WR, Pullen SM, Hogg A, Helsby NA, Hicks KO, et al. (2002) Quantitation of bystander effects in nitroreductase suicide gene therapy using three-dimensional cell cultures. Cancer Res 62: 1425-1432.
60. Hanna NN, Mauceri HJ, Wayne JD, Hallahan DE, Kufe DW, et al. (1997) Virally directed cytosine deaminase/5-fluorocytosine gene therapy enhances radiation response in human cancer xenografts. Cancer Res 57: 4205-4209.