Adiponectin prevents islet ischemia-reperfusion injury through the COX2-TNFα-NF-κB-dependent signal transduction pathway in mice

Journal of Endocrinology

Volumn 218, Issue 1, 2013, Pages 75-84

  Du, Xiaojiong ^a   He, Sirong ^b   Jiang, Yaowen ^a   Wei, Lingling ^c   Hu, Weiming ^a  

^a SICHUAN UNIVERSITY   (China)

^b SICHUAN UNIVERSITY   (China)

^c SICHUAN PROVINCIAL PEOPLE'S HOSPITAL   (China)

Author keywords

Adiponectin; Ischemia reperfusion; Islet transplantation

Indexed keywords

ADIPONECTIN; CYCLOOXYGENASE 2; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GRAFT DYSFUNCTION; HYPOXIA; MALE; MOUSE; NONHUMAN; PANCREAS ISLET; PANCREAS ISLET CELL; PANCREAS ISLET TRANSPLANTATION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REPERFUSION INJURY; SIGNAL TRANSDUCTION;

ADIPONECTIN; ISCHEMIA-REPERFUSION; ISLET TRANSPLANTATION;

ADIPONECTIN; ANIMALS; APOPTOSIS; CELL HYPOXIA; CYCLOOXYGENASE 2; HORMONE ANTAGONISTS; I-KAPPA B PROTEINS; INSULIN; ISLETS OF LANGERHANS; ISLETS OF LANGERHANS TRANSPLANTATION; MALE; MICE; MICE, KNOCKOUT; NF-KAPPA B; PHOSPHORYLATION; PROTECTIVE AGENTS; PROTEIN PROCESSING, POST-TRANSLATIONAL; REPERFUSION INJURY; SIGNAL TRANSDUCTION; TISSUE CULTURE TECHNIQUES; TRANSPLANTATION, HETEROTOPIC; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84878774257     PISSN: 00220795     EISSN: 14796805     Source Type: Journal    
DOI: 10.1530/JOE-12-0568     Document Type: Article

References (26)

1. Chang I, Kim S, Kim JY, Cho N, Kim YH, Kim HS, Lee MK, Kim KW & Lee MS 2003 Nuclear factor kB protects pancreatic b-cells from tumor necrosis factor-a-mediated apoptosis. Diabetes 52 1169-1175. (doi:10.2337/diabetes.52.5.1169)
2. Chen B, Liao WQ, Xu N, Xu H, Wen JY, Yu CA, Liu XY, Li CL, Zhao SM & Campbell W 2009 Adiponectin protects against cerebral ischemia- reperfusion injury through anti-inflammatory action. Brain Research 1273 129-137. (doi:10.1016/j.brainres.2009.04.002)
3. Cheng CF, Lian WS, Chen SH, Lai PF, Li HF, Lan YF, Cheng WT & Lin H 2012 Protective effects of adiponectin against renal ischemia- reperfusion injury via prostacyclin-PPARa-heme oxygenase-1 signaling pathway. Journal of Cellular Physiology 227 239-249. (doi:10.1002/ jcp.22726)
4. Davalli AM, Scaglia L, Zangen DH, Hollister J, Bonner-Weir S & Weir GC 1996 Vulnerability of islets in the immediate posttransplantation period. Dynamic changes in structure and function. Diabetes 45 1161-1167. (doi:10.2337/diabetes.45.9.1161)
5. Elias-Miro M, Massip-Salcedo M, Jimenez-Castro M & Peralta C 2011 Does adiponectin benefit steatotic liver transplantation?. Liver Transplantation 17 993-1004. (doi:10.1002/lt.22358)
6. Goldstein BJ, Scalia RG & Ma XL 2009 Protective vascular and myocardial effects of adiponectin. Nature Clinical Practice Cardiovascular Medicine 6 27-35. (doi:10.1038/ncpcardio1398)
7. Jung T, Schauer U, Heusser C, Neumann C & Rieger C 1993 Detection of intracellular cytokines by flow cytometry. Journal of Immunological Methods 159 197-207. (doi:10.1016/0022-1759(93)90158-4)
8. Kondo K, Shibata R, Unno K, Shimano M, Ishii M, Kito T, Shintani S, Walsh K, Ouchi N & Murohara T 2010 Impact of a single intracoronary administration of adiponectin on myocardial ischemia/reperfusion injury in a pig model. Circulation Cardiovascular Interventions 3 166-173. (doi:10.1161/CIRCINTERVENTIONS.109.872044)
9. Liuwantara D, Elliot M, Smith MW, Yam AO, Walters SN, Marino E, McShea A & Grey ST 2006 Nuclear factor-kB regulates b-cell death: a critical role for A20 in b-cell protection. Diabetes 55 2491-2501. (doi:10.2337/db06-0142)
10. Luo P, Chang HH, Zhou Y, Zhang S, Hwang SH, Morisseau C, Wang CY, Inscho EW, Hammock BD & Wang MH 2010 Inhibition or deletion of soluble epoxide hydrolase prevents hyperglycemia, promotes insulin secretion, and reduces islet apoptosis. Journal of Pharmacology and Experimental Therapeutics 334 430-438. (doi:10.1124/jpet.110.167544)
11. Maeda N, Shimomura I, Kishida K, Nishizawa H,Matsuda M, Nagaretani H, Furuyama N, Kondo H, Takahashi M, Arita Y et al. 2002 Diet-induced insulin resistance inmice lacking adiponectin/ACRP30. NatureMedicine 8 731-737. (doi:10.1038/nm724)
12. Malinin NL, Boldin MP, Kovalenko AV, Wallach D 1997 MAP3K-related kinase involved in NF-kB induction by TNF, CD95 and IL-1. Nature 385 540-544. (doi:10.1038/385540a0)
13. Massip-SalcedoM, Zaouali MA, Padrissa-Altés S, Casillas-Ramirez A, Rodés J, Roselló-Catafau J & Peralta C 2008 Activation of peroxisome proliferator- activated receptor-a inhibits the injurious effects of adiponectin in rat steatotic liver undergoing ischemia-reperfusion. Hepatology 47 461-472. (doi:10.1002/hep.21935)
14. Matsuda T, Omori K, Vuong T, Pascual M, Valiente L, Ferreri K, Todorov I, Kuroda Y, Smith CV, Kandeel F et al. 2005 Inhibition of p38 pathway suppresses human islet production of pro-inflammatory cytokines and improves islet graft function. American Journal of Transplantation 5 484-493. (doi:10.1046/j.1600-6143.2004.00716.x)
15. Matsuoka N, Itoh T, Watarai H, Sekine-Kondo E, Nagata N, Okamoto K, Mera T, Yamamoto H, Yamada S, Maruyama I et al. 2010 High-mobility group box 1 is involved in the initial events of early loss of transplanted islets in mice. Journal of Clinical Investigation 120 735-743. (doi:10.1172/JCI41360)
16. Montaña E, Bonner-Weir S, Weir GC 1993 b Cell mass and growth after syngeneic islet cell transplantation in normal and streptozocin diabetic C57BL/6 mice. Journal of Clinical Investigation 91 780-787. (doi:10.1172/JCI116297)
17. Negi S, Jetha A, Aikin R, Hasilo C, Sladek R & Paraskevas S 2012 Analysis of b-cell gene expression reveals inflammatory signaling and evidence of dedifferentiation following human islet isolation and culture. PLoS ONE 7 e30 415. (doi:10.1371/journal.pone.0030415)
18. Ohashi K, Ouchi N & Matsuzawa Y 2012 Anti-inflammatory and antiatherogenic properties of adiponectin. Biochimie 10 2137-2142. (doi:10.1016/j.biochi.2012.06.008)
19. Parazzoli S, Harmon J, Vallerie SN, Zhang T, Zhou H & Robertson RP 2012 COX-2, not mPGES-1, is the dominant regulator of IL-1b-induced PGE2 production and subsequent inhibition of pancreatic islet b-cell function during inflammation. Journal of Biological Chemistry 287 32246-32253. (doi:10.1074/jbc.M112.364612)
20. Porras DL, Wang Y, Zhou P, Molinero LL & Alegre ML 2012 Role of T-cell-specific nuclear factor kB in islet allograft rejection. Transplantation 93 976-982. (doi:10.1097/TP.0b013e31824d11d7)
21. Seki H, Tasaka S, Fukunaga K, Shiraishi Y, Moriyama K, Miyamoto K, Nakano Y, Matsunaga N, Takashima K, Matsumoto T et al. 2010 Effect of Toll-like receptor 4 inhibitor on LPS-induced lung injury. Inflammation Research 59 837-845. (doi:10.1007/s00011-010-0195-3)
22. Shibata R, Sato K, PimentelDR, Takemura Y, Kihara S,Ohashi K, Funahashi T, Ouchi N,Walsh K 2005 Adiponectin protects against myocardial ischemia-reperfusion injury through AMPK- and COX-2-dependent mechanisms. Nature Medicine 11 1096-1103. (doi:10.1038/nm1295)
23. Siasos G, Tousoulis D, Kollia C, Oikonomou E, Siasou Z, Stefanadis C & Papavassiliou AG 2012 Adiponectin and cardiovascular disease: mechanisms and new therapeutic approaches. Current Medicinal Chemistry 19 1193-1209. (doi:10.2174/092986712799320583)
24. Sklavos MM, Bertera S, Tse HM, Bottino R, He J, Beilke JN, Coulombe MG, Gill RG, Crapo JD, Trucco M et al. 2010 Redox modulation protects islets from transplant-related injury. Diabetes 59 1731-1738. (doi:10.2337/db09-0588)
25. Tak PP, Firestein GS 2001 NF-kB: a key role in inflammatory diseases. Journal of Clinical Investigation 107 7-11. (doi:10.1172/JCI11830)
26. Yang WS, LeeWJ, Funahashi T, Tanaka S,Matsuzawa Y, Chao CL, Chen CL, Tai TY & Chuang LM 2001 Weight reduction increases plasma levels of an adipose-derived anti-inflammatory protein, adiponectin. Journal of Clinical Endocrinology and Metabolism 86 3815-3819. (doi:10.1210/jc. 86.8.3815)