Genomic aberrations in normal tissue adjacent to HER2-amplified breast cancers: Field cancerization or contaminating tumor cells?

Breast Cancer Research and Treatment

Volumn 136, Issue 3, 2012, Pages 693-703

  Sadanandam, Anguraj ^a,f   Lal, Aseem ^b   Benz, Stephen C ^c   Eppenberger Castori, Serenella ^d   Scott, Gary ^e   Gray, Joe W ^a,b,g   Spellman, Paul ^a,g   Waldman, Fred ^b,h   Benz, Christopher C ^b,e  

^a LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c Five3 Genomics   (United States)

^d UNIVERSITY HOSPITAL BASEL   (Switzerland)

^e BUCK INSTITUTE FOR RESEARCH ON AGING   (United States)

^f SWISS INSTITUTE OF BIOINFORMATICS   (Switzerland)

^g OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^h QUEST DIAGNOSTICS NICHOLS INSTITUTE   (United States)

Author keywords

HER2 ERBB2 amplified breast tumors; Normal adjacent tissue

Indexed keywords

ADULT; AGED; ALLELE; AMPLICON; ARTICLE; BREAST CANCER; CLINICAL ARTICLE; CONTROLLED STUDY; COPY NUMBER VARIATION; DNA EXTRACTION; DNA MICROARRAY; GENE LOCUS; GENETIC DISORDER; HAPLOTYPE; HER2 POSITIVE BREAST CANCER; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; ONCOGENE NEU; PILOT STUDY; PRIORITY JOURNAL; TUMOR INVASION; TUMOR MICROENVIRONMENT; UPREGULATION; BREAST TUMOR; FEMALE; GENETICS; METABOLISM; MIDDLE AGED; PATHOLOGY; REFERENCE VALUE;

EPIDERMAL GROWTH FACTOR RECEPTOR 2; ERBB2 PROTEIN, HUMAN;

ADULT; BREAST NEOPLASMS; DNA COPY NUMBER VARIATIONS; FEMALE; HUMANS; MIDDLE AGED; PILOT PROJECTS; RECEPTOR, ERBB-2; REFERENCE VALUES; TUMOR MICROENVIRONMENT;

EID: 84878767379     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-012-2290-3     Document Type: Article

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