Quantitative DNA fingerprinting may distinguish new primary breast cancer from disease recurrence

Journal of Clinical Oncology

Volumn 22, Issue 10, 2004, Pages 1830-1838

  Schlechter, Benjamin L ^a   Yang, Qiong ^a   Larson, Pamela S ^a   Golubeva, Arina ^a   Blanchard, Rita A ^a   de Las Morenas, Antonio ^a   Rosenberg, Carol L ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLELE; ARTICLE; BREAST CANCER; CANCER GROWTH; CANCER RECURRENCE; CLONAL VARIATION; CONTROLLED STUDY; DNA FINGERPRINTING; FEMALE; HETEROZYGOSITY LOSS; HUMAN; PRIORITY JOURNAL; SCORING SYSTEM; BREAST TUMOR; CASE CONTROL STUDY; EVALUATION; GENETICS; METHODOLOGY; PATHOLOGY; PREDICTION AND FORECASTING; REPRODUCIBILITY; SECOND CANCER; TUMOR RECURRENCE;

ALLELES; BREAST NEOPLASMS; CASE-CONTROL STUDIES; DNA FINGERPRINTING; FEMALE; HUMANS; LOSS OF HETEROZYGOSITY; NEOPLASM RECURRENCE, LOCAL; NEOPLASMS, SECOND PRIMARY; PREDICTIVE VALUE OF TESTS; REPRODUCIBILITY OF RESULTS;

EID: 3042701606     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/JCO.2004.05.123     Document Type: Article

References (44)

1. Rosen PP, Groshen S, Kinne DW, et al: Contralateral breast carcinoma: An assessment of risk and prognosis in stage I (T1N0M0) and stage II (T1N1M0) patients with 20-year follow-up. Surgery 106:904-910, 1989
2. Gogas J, Markopoulos C, Skandalakis P, et al: Bilateral breast cancer. Am Surg 59:733-735, 1993
3. Anastasiadis PG, Liberis VA, Koutlaki NG, et al: Incidence and detection of contralateral breast cancer. Breast J 6:178-182, 2000
4. Heron DE, Komarnicky LT, Hyslop T, et al: Bilateral breast carcinoma: Risk factors and outcomes for patients with synchronous and metachronous disease. Cancer 88:2739-2750, 2000
5. Ries LAG, Eisner MP, Kosary CL, et al: SEER Cancer Statistics Review, 1973-1999. Bethesda, MD, National Cancer Institute, 2002
6. Chaudary MA, Millis RR, Hoskins EO, et al: Bilateral primary breast cancer: A prospective study of disease incidence. Br J Surg 71:711-714, 1984
7. Smith TE, Lee D, Turner BC, et al: True recurrence vs. new primary ipsilateral breast tumor relapse: An analysis of clinical and pathologic differences and their implications in natural history, prognoses, and therapeutic management. Int J Radiat Oncol Biol Phys 48:1281-1289, 2000
8. Huang E, Buchholz TA, Meric F, et al: Classifying local disease recurrences after breast conservation therapy based on location and histology: New primary tumors have more favorable outcomes than true local disease recurrences. Cancer 95:2059-2067, 2002
9. van der Sijp JR, van Meerbeeck JP, Maat AP, et al: Determination of the molecular relationship between multiple tumors within one patient is of clinical importance. J Clin Oncol 20:1105-1114, 2002
10. Noguchi S, Motomura K, Inaji H, et al: Differentiation of primary and secondary breast cancer with clonal analysis. Surgery 115:458-462, 1994
11. Shibata A, Tsai YC, Press MF, et al: Clonal analysis of bilateral breast cancer. Clin Cancer Res 2:743-748, 1996
12. Janschek E, Kandioler-Eckersberger D, Ludwig C, et al: Contralateral breast cancer: Molecular differentiation between metastasis and second primary cancer. Breast Cancer Res Treat 67:1-8, 2001
13. Ackerman J, Baunoch DA, Gimotty P, et al: The role of p53 mutations in bilateral breast carcinoma. Mod Pathol 8:244-248, 1995
14. Unger MA, Rishi M, Clemmer VB, et al: Characterization of adjacent breast tumors using oligonucleotide microarrays. Breast Cancer Res 3:336-341, 2001
15. Dickson RB, Lippman ME: Cancer of the breast, in Rosenberg SA (ed): Cancer Principles and Practice of Oncology (ed 6). Philadelphia, PA, Lippincott, Williams & Wilkins, 2001, pp 1633-1647
16. Kerangueven F, Noguchi T, Coulier F, et al: Genome-wide search for loss of heterozygosity shows extensive genetic diversity of human breast carcinomas. Cancer Res 57:5469-5474, 1997
17. Osborne RJ, Hamshere MG: A genome-wide map showing common regions of loss of heterozygosity/allelic imbalance in breast cancer. Cancer Res 60:3706-3712, 2000
18. Shen CY, Yu JC, Lo YL, et al: Genome-wide search for loss of heterozygosity using laser capture microdissected tissue of breast carcinoma: An implication for mutator phenotype and breast cancer pathogenesis. Cancer Res 60:3884-3892, 2000
19. Chen LC, Kurisu W, Ljung BM, et al: Heterogeneity for allelic loss in human breast cancer. J Natl Cancer Inst 84:506-510, 1992
20. Larson PS, De Las Morenas A, Bennett SR, et al: Loss of heterozygosity or allele imbalance in histologically normal breast epithelium is distinct from loss of heterozygosity or allele imbalance in co-existing carcinomas. Am J Pathol 161:283-290, 2002
21. Imyanitov EN, Suspitsin EN, Grigoriev MY, et al: Concordance of allelic imbalance profiles in synchronous and metachronous bilateral breast carcinomas. Int J Cancer 100: 557-564, 2002
22. Lininger RA, Fujii H, Man YG, et al: Comparison of loss heterozygosity in primary and recurrent ductal carcinoma in situ of the breast. Mod Pathol 11:1151-1159, 1998
23. Lichy JH, Dalbegue F, Zavar M, et al: Genetic heterogeneity in ductal carcinoma of the breast. Lab Invest 80:291-301, 2000
24. Fujii H, Marsh C, Cairns P, et al: Genetic divergence in the clonal evolution of breast cancer. Cancer Res 56:1493-1497, 1996
25. Kuukasjarvi T, Karhu R, Tanner M, et al: Genetic heterogeneity and clonal evolution underlying development of asynchronous metastasis in human breast cancer. Cancer Res 57:1597-1604, 1997
26. Nakayama T, Teback B, Turner R, et al: Molecular clonality of in-transit melanoma metastasis. Am J Pathol 158:1371-1378, 2001
27. Abeln EC, Kuipers-Dijkshoorn NJ, Berns EM, et al: Molecular genetic evidence for unifocal origin of advanced epithelial ovarian cancer and for minor clonal divergence. Br J Cancer 72:1330-1336, 1995
28. Chen YJ, Yeh SH, Chen JT, et al: Chromosomal changes and clonality relationship between primary and recurrent hepatocellular carcinoma. Gastroenterology 119:431-440, 2000
29. Shimizu S, Yatabe Y, Koshikawa T, et al: High frequency of clonally related tumors in cases of multiple synchronous lung cancers as revealed by molecular diagnosis. Clin Cancer Res 6:3994-3999, 2000
30. Kollias J, Man S, Marafie M, et al: Loss of heterozygosity in bilateral breast cancer. Breast Cancer Res Treat 64:241-251, 2000
31. Kung FY, Tse GM, Lo KW, et al: Metachronous bilateral mammary metaplastic and infiltrating duct carcinomas: A molecular study for clonality. Hum Pathol 33:677-679, 2002
32. Agelopoulos K, Tidow N, Korsching E, et al: Molecular cytogenetic investigations of synchronous bilateral breast cancer. J Clin Pathol 56:660-665, 2003
33. Larson PS, de las Morenas A, Cupples LA, et al: Genetically abnormal clones in histologically normal breast tissue. Am J Pathol 152: 1591-1598, 1998
34. Diaz-Cano SJ, Blanes A, Wolfe HJ: PCR techniques for clonality assays. Diagn Mol Pathol 10:24-33, 2001
35. Tomlinson IP, Lambros MB, Roylance RR: Loss of heterozygosity analysis: Practically and conceptually flawed? Genes Chromosomes Cancer 34:349-353, 2002
36. Aubele M, Mattis A, Zitzelsberger H, et al: Intratumoral heterogeneity in breast carcinoma revealed by laser-microdissection and comparative genomic hybridization. Cancer Genet Cytogenet 110:94-102, 1999
37. Glockner S, Buurman H, Kleeberger W, et al: Marked intratumoral heterogeneity of c-myc and cyclinD1 but not of c-erbB2 amplification in breast cancer. Lab Invest 82:1419-1426, 2002
38. Sterns EE, Fletcher WA: Bilateral cancer of the breast: A review of clinical, histologic, and immunohistologic characteristics. Surgery 110: 617-622, 1991
39. Tirkkonen M, Johannsson O, Agnarsson BA, et al: Distinct somatic genetic changes associated with tumor progression in carriers of BRCA1 and BRCA2 germ-line mutations. Cancer Res 57:1222-1227, 1997
40. Hedenfalk I, Duggan D, Chen Y, et al: Gene-expression profiles in hereditary breast cancer. N Engl J Med 344:539-548, 2001
41. Wistuba II, Tomlinson GE, Behrens C, et al: Two identical triplet sisters carrying a germline BRCA1 gene mutation acquire very similar breast cancer somatic mutations at multiple other sites throughout the genome. Genes Chromosomes Cancer 28:359-369, 2000
42. Pandis N, Teixeira MR, Gerdes AM, et al: Chromosome abnormalities in bilateral breast carcinomas: Cytogenetic evaluation of the clonal origin of multiple primary tumors. Cancer 76:250-258, 1995
43. Haffty BG, Carter D, Flynn SD, et al: Local recurrence versus new primary: Clinical analysis of 82 breast relapses and potential applications for genetic fingerprinting. Int J Radiat Oncol Biol Phys 27:575-583, 1993
44. Regitnig P, Moser R, Thalhammer M, et al: Microsatellite analysis of breast carcinoma and corresponding local recurrences. J Pathol 198: 190-197, 2002