메뉴 건너뛰기




Volumn 304, Issue 11, 2013, Pages

Arcuate nucleus injection of an anti-insulin affibody prevents the sympathetic response to insulin

Author keywords

Blood pressure; Lumbar; Obesity; Renal; Sympathetic nerve activity

Indexed keywords

INSULIN; INSULIN ANTIBODY;

EID: 84878766034     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00081.2013     Document Type: Article
Times cited : (39)

References (51)
  • 1
    • 34547642988 scopus 로고    scopus 로고
    • Increased dietary salt enhances sympathoexcitatory and sympathoinhibitory responses from the rostral ventrolateral medulla
    • Adams JM, Madden CJ, Sved AF, Stocker SD. Increased dietary salt enhances sympathoexcitatory and sympathoinhibitory responses from the rostral ventrolateral medulla. Hypertension 50: 354-359, 2007.
    • (2007) Hypertension , vol.50 , pp. 354-359
    • Adams, J.M.1    Madden, C.J.2    Sved, A.F.3    Stocker, S.D.4
  • 3
    • 0025995364 scopus 로고
    • Hyperinsulinemia produces both sympathetic neural activation and vasodilation in normal humans
    • Anderson EA, Hoffman RP, Balon TW, Sinkey CA, Mark AL. Hyperinsulinemia produces both sympathetic neural activation and vasodilation in normal humans. J Clin Invest 87: 2246-2252, 1991.
    • (1991) J Clin Invest , vol.87 , pp. 2246-2252
    • Anderson, E.A.1    Hoffman, R.P.2    Balon, T.W.3    Sinkey, C.A.4    Mark, A.L.5
  • 4
    • 74949087576 scopus 로고    scopus 로고
    • Glutamatergic receptor activation in the rostral ventrolateral medulla mediates the sympathoexcitatory response to hyperinsulinemia
    • Bardgett ME, McCarthy JJ, Stocker SD. Glutamatergic receptor activation in the rostral ventrolateral medulla mediates the sympathoexcitatory response to hyperinsulinemia. Hypertension 55: 284-290, 2010.
    • (2010) Hypertension , vol.55 , pp. 284-290
    • Bardgett, M.E.1    McCarthy, J.J.2    Stocker, S.D.3
  • 5
    • 0027361094 scopus 로고
    • Saturable transport of insulin from plasma into the central nervous system of dogs in vivo. A mechanism for regulated insulin delivery to the brain
    • Baura GD, Foster DM, Porte D Jr, Kahn SE, Bergman RN, Cobelli C, Schwartz MW. Saturable transport of insulin from plasma into the central nervous system of dogs in vivo. A mechanism for regulated insulin delivery to the brain. J Clin Invest 92: 1824-1830, 1993.
    • (1993) J Clin Invest , vol.92 , pp. 1824-1830
    • Baura, G.D.1    Foster, D.M.2    Porte Jr., D.3    Kahn, S.E.4    Bergman, R.N.5    Cobelli, C.6    Schwartz, M.W.7
  • 6
    • 1642564326 scopus 로고    scopus 로고
    • Dual viral transneuronal tracing of central autonomic circuits involved in the innervation of the two kidneys in rat
    • Cano G, Card JP, Sved AF. Dual viral transneuronal tracing of central autonomic circuits involved in the innervation of the two kidneys in rat. J Comp Neurol 471: 462-481, 2004.
    • (2004) J Comp Neurol , vol.471 , pp. 462-481
    • Cano, G.1    Card, J.P.2    Sved, A.F.3
  • 7
    • 0035829144 scopus 로고    scopus 로고
    • Characterization of the central nervous system innervation of the rat spleen using viral transneuronal tracing
    • Cano G, Sved AF, Rinaman L, Rabin BS, Card JP. Characterization of the central nervous system innervation of the rat spleen using viral transneuronal tracing. J Comp Neurol 439: 1-18, 2001.
    • (2001) J Comp Neurol , vol.439 , pp. 1-18
    • Cano, G.1    Sved, A.F.2    Rinaman, L.3    Rabin, B.S.4    Card, J.P.5
  • 8
    • 79953156262 scopus 로고    scopus 로고
    • Insulin acts in the arcuate nucleus to increase lumbar sympathetic nerve activity and baroreflex function in rats
    • Cassaglia PA, Hermes SM, Aicher SA, Brooks VL. Insulin acts in the arcuate nucleus to increase lumbar sympathetic nerve activity and baroreflex function in rats. J Physiol 589: 1643-1662, 2011.
    • (2011) J Physiol , vol.589 , pp. 1643-1662
    • Cassaglia, P.A.1    Hermes, S.M.2    Aicher, S.A.3    Brooks, V.L.4
  • 14
    • 0032568488 scopus 로고    scopus 로고
    • Body weight reduction, sympathetic nerve traffic, and arterial baroreflex in obese normotensive humans
    • Grassi G, Seravalle G, Colombo M, Bolla G, Cattaneo BM, Cavagnini F, Mancia G. Body weight reduction, sympathetic nerve traffic, and arterial baroreflex in obese normotensive humans. Circulation 97: 2037-2042, 1998.
    • (1998) Circulation , vol.97 , pp. 2037-2042
    • Grassi, G.1    Seravalle, G.2    Colombo, M.3    Bolla, G.4    Cattaneo, B.M.5    Cavagnini, F.6    Mancia, G.7
  • 15
    • 0028143715 scopus 로고
    • The effect of metformin and insulin on sympathetic nerve activity, norepinephrine spillover and blood pressure in obese, insulin resistant, normoglycemic, hypertensive men
    • Gudbjornsdottir S, Friberg P, Elam M, Attvall S, Lonnroth P, Wallin BG. The effect of metformin and insulin on sympathetic nerve activity, norepinephrine spillover and blood pressure in obese, insulin resistant, normoglycemic, hypertensive men. Blood Press 3: 394-403, 1994.
    • (1994) Blood Press , vol.3 , pp. 394-403
    • Gudbjornsdottir, S.1    Friberg, P.2    Elam, M.3    Attvall, S.4    Lonnroth, P.5    Wallin, B.G.6
  • 17
    • 0030885584 scopus 로고    scopus 로고
    • CNS sites involved in sympathetic and parasympathetic control of the pancreas: A viral tracing study
    • Jansen AS, Hoffman JL, Loewy AD. CNS sites involved in sympathetic and parasympathetic control of the pancreas: a viral tracing study. Brain Res 766: 29-38, 1997.
    • (1997) Brain Res , vol.766 , pp. 29-38
    • Jansen, A.S.1    Hoffman, J.L.2    Loewy, A.D.3
  • 18
    • 0033857975 scopus 로고    scopus 로고
    • Obesity induced by a high-fat diet is associated with reduced brain insulin transport in dogs
    • Kaiyala KJ, Prigeon RL, Kahn SE, Woods SC, Schwartz MW. Obesity induced by a high-fat diet is associated with reduced brain insulin transport in dogs. Diabetes 49: 1525-1533, 2000.
    • (2000) Diabetes , vol.49 , pp. 1525-1533
    • Kaiyala, K.J.1    Prigeon, R.L.2    Kahn, S.E.3    Woods, S.C.4    Schwartz, M.W.5
  • 19
    • 84866466565 scopus 로고    scopus 로고
    • Cardiovascular responses to chemical stimulation of the hypothalamic arcuate nucleus in the rat: Role of the hypothalamic paraventricular nucleus
    • Kawabe T, Kawabe K, Sapru HN. Cardiovascular responses to chemical stimulation of the hypothalamic arcuate nucleus in the rat: role of the hypothalamic paraventricular nucleus. PLos One 7: e45180, 2012.
    • (2012) PLos One , vol.7
    • Kawabe, T.1    Kawabe, K.2    Sapru, H.N.3
  • 20
    • 84871666264 scopus 로고    scopus 로고
    • Effect of barodenervation on cardiovascular responses elicited from the hypothalamic arcuate nucleus of the rat
    • Kawabe T, Kawabe K, Sapru HN. Effect of barodenervation on cardiovascular responses elicited from the hypothalamic arcuate nucleus of the rat. PLos One 7: e53111, 2012.
    • (2012) PLos One , vol.7
    • Kawabe, T.1    Kawabe, K.2    Sapru, H.N.3
  • 21
    • 33645451436 scopus 로고    scopus 로고
    • Rostral elements of sympatho-motor circuitry: A virally mediated transsynaptic tracing study
    • Kerman IA, Akil H, Watson SJ. Rostral elements of sympatho-motor circuitry: a virally mediated transsynaptic tracing study. J Neurosci 26: 3423-3433, 2006.
    • (2006) J Neurosci , vol.26 , pp. 3423-3433
    • Kerman, I.A.1    Akil, H.2    Watson, S.J.3
  • 24
    • 0035066361 scopus 로고    scopus 로고
    • Insulin-mediated sympathetic stimulation: Role in the pathogenesis of obesity-related hypertension (or, how insulin affects blood pressure, and why)
    • Landsberg L. Insulin-mediated sympathetic stimulation: role in the pathogenesis of obesity-related hypertension (or, how insulin affects blood pressure, and why). J Hypertens 19: 523-528, 2001.
    • (2001) J Hypertens , vol.19 , pp. 523-528
    • Landsberg, L.1
  • 25
    • 84874363892 scopus 로고    scopus 로고
    • Obesity-related hypertension and the role of insulin and leptin in high-fat-fed rabbits
    • Lim K, Burke SL, Head GA. Obesity-related hypertension and the role of insulin and leptin in high-fat-fed rabbits. Hypertension 61: 628-634, 2013.
    • (2013) Hypertension , vol.61 , pp. 628-634
    • Lim, K.1    Burke, S.L.2    Head, G.A.3
  • 26
    • 0025612094 scopus 로고
    • Localization of insulin receptor mRNA in rat brain by in situ hybridization
    • Marks JL, Porte D Jr, Stahl WL, Baskin DG. Localization of insulin receptor mRNA in rat brain by in situ hybridization. Endocrinology 127: 3234-3236, 1990.
    • (1990) Endocrinology , vol.127 , pp. 3234-3236
    • Marks, J.L.1    Porte Jr., D.2    Stahl, W.L.3    Baskin, D.G.4
  • 27
    • 0033810868 scopus 로고    scopus 로고
    • Relation of leptin and insulin to adiposity-associated elevations in sympathetic activity with age in humans
    • Monroe MB, Van Pelt RE, Schiller BC, Seals DR, Jones PP. Relation of leptin and insulin to adiposity-associated elevations in sympathetic activity with age in humans. Int J Obes Relat Metab Disord 24: 1183-1187, 2000.
    • (2000) Int J Obes Relat Metab Disord , vol.24 , pp. 1183-1187
    • Monroe, M.B.1    van Pelt, R.E.2    Schiller, B.C.3    Seals, D.R.4    Jones, P.P.5
  • 29
    • 77955854156 scopus 로고    scopus 로고
    • Differential effects of insulin on sympathetic nerve activity in agouti obese mice
    • Morgan DA, Rahmouni K. Differential effects of insulin on sympathetic nerve activity in agouti obese mice. J Hypertens 28: 1913-1919, 2010.
    • (2010) J Hypertens , vol.28 , pp. 1913-1919
    • Morgan, D.A.1    Rahmouni, K.2
  • 30
    • 0028216451 scopus 로고
    • Anteroventral third ventricle lesions abolish lumbar sympathetic responses to insulin
    • Muntzel M, Beltz T, Mark AL, Johnson AK. Anteroventral third ventricle lesions abolish lumbar sympathetic responses to insulin. Hypertension 23: 1059-1062, 1994.
    • (1994) Hypertension , vol.23 , pp. 1059-1062
    • Muntzel, M.1    Beltz, T.2    Mark, A.L.3    Johnson, A.K.4
  • 32
    • 0028005885 scopus 로고
    • Insulin acts centrally to enhance reflex tachycardia in conscious rats
    • Okada M, Bunag RD. Insulin acts centrally to enhance reflex tachycardia in conscious rats. Am J Physiol Regul Integr Comp Physiol 266: R481-R486, 1994.
    • (1994) Am J Physiol Regul Integr Comp Physiol , vol.266
    • Okada, M.1    Bunag, R.D.2
  • 33
    • 0015977740 scopus 로고
    • Comparative measurements of glucose, beta-hydroxybutyrate, acetoacetate, and insulin in blood and cerebrospinal fluid during starvation
    • Owen OE, Reichard GA Jr, Boden G, Shuman C. Comparative measurements of glucose, beta-hydroxybutyrate, acetoacetate, and insulin in blood and cerebrospinal fluid during starvation. Metabolism 23: 7-14, 1974.
    • (1974) Metabolism , vol.23 , pp. 7-14
    • Owen, O.E.1    Reichard Jr., G.A.2    Boden, G.3    Shuman, C.4
  • 34
    • 0023499457 scopus 로고
    • Pro-opiomelanocortin-derived peptides (ACTH/beta-endorphin/alpha-MSH) in brainstem baroreceptor areas of the rat
    • Palkovits M, Mezey E, Eskay RL. Pro-opiomelanocortin-derived peptides (ACTH/beta-endorphin/alpha-MSH) in brainstem baroreceptor areas of the rat. Brain Res 436: 323-338, 1987.
    • (1987) Brain Res , vol.436 , pp. 323-338
    • Palkovits, M.1    Mezey, E.2    Eskay, R.L.3
  • 37
    • 38549132891 scopus 로고    scopus 로고
    • Insulin in the brain increases gain of baroreflex control of heart rate and lumbar sympathetic nerve activity
    • Pricher MP, Freeman KL, Brooks VL. Insulin in the brain increases gain of baroreflex control of heart rate and lumbar sympathetic nerve activity. Hypertension 51: 514-520, 2008.
    • (2008) Hypertension , vol.51 , pp. 514-520
    • Pricher, M.P.1    Freeman, K.L.2    Brooks, V.L.3
  • 38
    • 0038149085 scopus 로고    scopus 로고
    • Role of melanocortin-4 receptors in mediating renal sympathoactivation to leptin and insulin
    • Rahmouni K, Haynes WG, Morgan DA, Mark AL. Role of melanocortin-4 receptors in mediating renal sympathoactivation to leptin and insulin. J Neurosci 23: 5998-6004, 2003.
    • (2003) J Neurosci , vol.23 , pp. 5998-6004
    • Rahmouni, K.1    Haynes, W.G.2    Morgan, D.A.3    Mark, A.L.4
  • 40
    • 0019483909 scopus 로고
    • Effect of insulin and glucose infusions on sympathetic nervous system activity in normal man
    • Rowe JW, Young JB, Minaker KL, Stevens AL, Pallotta J, Landsberg L. Effect of insulin and glucose infusions on sympathetic nervous system activity in normal man. Diabetes 30: 219-225, 1981.
    • (1981) Diabetes , vol.30 , pp. 219-225
    • Rowe, J.W.1    Young, J.B.2    Minaker, K.L.3    Stevens, A.L.4    Pallotta, J.5    Landsberg, L.6
  • 43
    • 33847077261 scopus 로고    scopus 로고
    • Neurons of the rostral ventrolateral medulla contribute to obesity-induced hypertension in rats
    • Stocker SD, Meador R, Adams JM. Neurons of the rostral ventrolateral medulla contribute to obesity-induced hypertension in rats. Hypertension 49: 640-646, 2007.
    • (2007) Hypertension , vol.49 , pp. 640-646
    • Stocker, S.D.1    Meador, R.2    Adams, J.M.3
  • 44
    • 50249120768 scopus 로고    scopus 로고
    • Synaptic release of GABA by AgRP neurons is required for normal regulation of energy balance
    • Tong Q, Ye CP, Jones JE, Elmquist JK, Lowell BB. Synaptic release of GABA by AgRP neurons is required for normal regulation of energy balance. Nat Neurosci 11: 998-1000, 2008.
    • (2008) Nat Neurosci , vol.11 , pp. 998-1000
    • Tong, Q.1    Ye, C.P.2    Jones, J.E.3    Elmquist, J.K.4    Lowell, B.B.5
  • 45
    • 0030774228 scopus 로고    scopus 로고
    • Regional sympathetic nervous activity and oxygen consumption in obese normotensive human subjects
    • Vaz M, Jennings G, Turner A, Cox H, Lambert G, Esler M. Regional sympathetic nervous activity and oxygen consumption in obese normotensive human subjects. Circulation 96: 3423-3429, 1997.
    • (1997) Circulation , vol.96 , pp. 3423-3429
    • Vaz, M.1    Jennings, G.2    Turner, A.3    Cox, H.4    Lambert, G.5    Esler, M.6
  • 46
    • 0029967740 scopus 로고    scopus 로고
    • Influence of insulin, sympathetic nervous system activity, and obesity on blood pressure: The Normative Aging Study
    • Ward KD, Sparrow D, Landsberg L, Young JB, Vokonas PS, Weiss ST. Influence of insulin, sympathetic nervous system activity, and obesity on blood pressure: the Normative Aging Study. J Hypertens 14: 301-308, 1996.
    • (1996) J Hypertens , vol.14 , pp. 301-308
    • Ward, K.D.1    Sparrow, D.2    Landsberg, L.3    Young, J.B.4    Vokonas, P.S.5    Weiss, S.T.6
  • 47
    • 79953252126 scopus 로고    scopus 로고
    • Sympathetic response to insulin is mediated by melanocortin 3/4 receptors in the hypothalamic paraventricular nucleus
    • Ward KR, Bardgett JF, Wolfgang L, Stocker SD. Sympathetic response to insulin is mediated by melanocortin 3/4 receptors in the hypothalamic paraventricular nucleus. Hypertension 57: 435-441, 2011.
    • (2011) Hypertension , vol.57 , pp. 435-441
    • Ward, K.R.1    Bardgett, J.F.2    Wolfgang, L.3    Stocker, S.D.4
  • 48
    • 0023271871 scopus 로고
    • Localization and characterization of insulin receptors in rat brain and pituitary gland using in vitro autoradiography and computerized densitometry
    • Werther GA, Hogg A, Oldfield BJ, McKinley MJ, Figdor R, Allen AM, Mendelsohn FA. Localization and characterization of insulin receptors in rat brain and pituitary gland using in vitro autoradiography and computerized densitometry. Endocrinology 121: 1562-1570, 1987.
    • (1987) Endocrinology , vol.121 , pp. 1562-1570
    • Werther, G.A.1    Hogg, A.2    Oldfield, B.J.3    McKinley, M.J.4    Figdor, R.5    Allen, A.M.6    Mendelsohn, F.A.7
  • 49
  • 50
    • 77956765040 scopus 로고    scopus 로고
    • Insulin enhances the gain of arterial baroreflex control of muscle sympathetic nerve activity in humans
    • Young CN, Deo SH, Chaudhary K, Thyfault JP, Fadel PJ. Insulin enhances the gain of arterial baroreflex control of muscle sympathetic nerve activity in humans. J Physiol 588: 3593-3603, 2010.
    • (2010) J Physiol , vol.588 , pp. 3593-3603
    • Young, C.N.1    Deo, S.H.2    Chaudhary, K.3    Thyfault, J.P.4    Fadel, P.J.5
  • 51
    • 84866325097 scopus 로고    scopus 로고
    • Rosiglitazone improves insulin sensitivity and baroreflex gain in rats with diet-induced obesity
    • Zhao D, McCully BH, Brooks VL. Rosiglitazone improves insulin sensitivity and baroreflex gain in rats with diet-induced obesity. J Pharmacol Exp Ther 343: 206-213, 2012.
    • (2012) J Pharmacol Exp Ther , vol.343 , pp. 206-213
    • Zhao, D.1    McCully, B.H.2    Brooks, V.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.