WDR26 functions as a scaffolding protein to promote Gβγ-mediated phospholipase C β2 (PLCβ2) activation in leukocytes

Journal of Biological Chemistry

Volumn 288, Issue 23, 2013, Pages 16715-16725

  Sun, Zhizeng ^a   Smrcka, Alan V ^b   Chen, Songhai ^a  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOSOLS; LEUKOCYTE MIGRATION; MEMBRANE TRANSLOCATION; PARTIAL ACTIVATION; PHOSPHOLIPASE C; REPEAT PROTEINS; SCAFFOLDING PROTEINS; SIGNALING COMPLEX;

OLIGOMERS; PROTEINS;

SCAFFOLDS (BIOLOGY);

GUANINE NUCLEOTIDE BINDING PROTEIN BETA SUBUNIT; GUANINE NUCLEOTIDE BINDING PROTEIN GAMMA SUBUNIT; PHOSPHOLIPASE C BETA2; SCAFFOLD PROTEIN; UNCLASSIFIED DRUG; WD REPEAT PROTEIN 26;

ARTICLE; BINDING AFFINITY; BINDING SITE; CELL TRANSPORT; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION;

CHEMOTAXIS; G PROTEIN ΒΓ; G PROTEIN-COUPLED RECEPTORS (GPCR); HETEROTRIMERIC G PROTEINS; PHOSPHATIDYLINOSITOL; PHOSPHOLIPASE C; WD40 REPEAT PROTEINS; WDR26;

BINDING SITES; CELL MEMBRANE; CYTOSOL; HEK293 CELLS; HUMANS; JURKAT CELLS; LEUKOCYTES; PHOSPHOLIPASE C BETA; PROTEIN BINDING; PROTEIN TRANSPORT; PROTEINS; SIGNAL TRANSDUCTION;

EID: 84878760741     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.462564     Document Type: Article

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