메뉴 건너뛰기




Volumn 139, Issue 2, 2013, Pages 351-360

Fulvestrant regulates epidermal growth factor (EGF) family ligands to activate EGF receptor (EGFR) signaling in breast cancer cells

Author keywords

Breast cancer cell lines; EGFR; EGFR ligands; Fulvestrant

Indexed keywords

AMPHIREGULIN; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPIREGULIN; ERLOTINIB; FULVESTRANT; LAPATINIB; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3;

EID: 84878759749     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-013-2541-y     Document Type: Article
Times cited : (19)

References (42)
  • 2
    • 79551584513 scopus 로고    scopus 로고
    • Antiestrogens and their therapeutic applications in breast cancer and other diseases
    • 21054173 10.1146/annurev-med-052209-100305 1:CAS:528:DC%2BC3MXivVWhtL0%3D
    • Ali S, Buluwela L, Coombes RC (2011) Antiestrogens and their therapeutic applications in breast cancer and other diseases. Annu Rev Med 62:217-232
    • (2011) Annu Rev Med , vol.62 , pp. 217-232
    • Ali, S.1    Buluwela, L.2    Coombes, R.C.3
  • 3
    • 0026395885 scopus 로고
    • A potent specific pure antiestrogen with clinical potential
    • 1855205 1:CAS:528:DyaK3MXlvFyrtr4%3D
    • Wakeling AE, Dukes M, Bowler J (1991) A potent specific pure antiestrogen with clinical potential. Cancer Res 51:3867-3873
    • (1991) Cancer Res , vol.51 , pp. 3867-3873
    • Wakeling, A.E.1    Dukes, M.2    Bowler, J.3
  • 4
    • 0029883292 scopus 로고    scopus 로고
    • Models of estrogen receptor regulation by estrogens and antiestrogens in breast cancer cell lines
    • 8625307 1:CAS:528:DyaK28XivF2ru74%3D
    • Pink JJ, Jordan VC (1996) Models of estrogen receptor regulation by estrogens and antiestrogens in breast cancer cell lines. Cancer Res 56:2321-2330
    • (1996) Cancer Res , vol.56 , pp. 2321-2330
    • Pink, J.J.1    Jordan, V.C.2
  • 5
    • 2442648038 scopus 로고    scopus 로고
    • Comparison of fulvestrant versus tamoxifen for the treatment of advanced breast cancer in postmenopausal women previously untreated with endocrine therapy: A multinational, double-blind, randomized trial
    • 15117982 10.1200/JCO.2004.02.112 1:CAS:528:DC%2BD2cXpsVWmu7w%3D
    • Howell A, Robertson JF, Abram P, Lichinitser MR, Elledge R, Bajetta E, Watanabe T, Morris C, Webster A, Dimery I, Osborne CK (2004) Comparison of fulvestrant versus tamoxifen for the treatment of advanced breast cancer in postmenopausal women previously untreated with endocrine therapy: a multinational, double-blind, randomized trial. J Clin Oncol 22:1605-1613
    • (2004) J Clin Oncol , vol.22 , pp. 1605-1613
    • Howell, A.1    Robertson, J.F.2    Abram, P.3    Lichinitser, M.R.4    Elledge, R.5    Bajetta, E.6    Watanabe, T.7    Morris, C.8    Webster, A.9    Dimery, I.10    Osborne, C.K.11
  • 7
    • 32944457272 scopus 로고    scopus 로고
    • Retrospective analysis of time to recurrence in the ATAC trial according to hormone receptor status: An hypothesis-generating study
    • 16234518 10.1200/JCO.2005.01.4829 1:CAS:528:DC%2BD2MXht1WrsrzE
    • Dowsett M, Cuzick J, Wale C, Howell T, Houghton J, Baum M (2005) Retrospective analysis of time to recurrence in the ATAC trial according to hormone receptor status: an hypothesis-generating study. J Clin Oncol 23:7512-7517
    • (2005) J Clin Oncol , vol.23 , pp. 7512-7517
    • Dowsett, M.1    Cuzick, J.2    Wale, C.3    Howell, T.4    Houghton, J.5    Baum, M.6
  • 8
    • 1842684035 scopus 로고    scopus 로고
    • Fulvestrant: An oestrogen receptor antagonist with a novel mechanism of action
    • 15094757 10.1038/sj.bjc.6601629 1:CAS:528:DC%2BD2cXjtFaktbY%3D
    • Osborne CK, Wakeling A, Nicholson RI (2004) Fulvestrant: an oestrogen receptor antagonist with a novel mechanism of action. Br J Cancer 90(Suppl 1):S2-S6
    • (2004) Br J Cancer , vol.90 , Issue.SUPPL. 1
    • Osborne, C.K.1    Wakeling, A.2    Nicholson, R.I.3
  • 9
  • 10
    • 80053341141 scopus 로고    scopus 로고
    • Simultaneous inhibition of estrogen receptor and the HER2 pathway in breast cancer: Effects of HER2 abundance
    • 21966546
    • Emde A, Mahlknecht G, Maslak K, Ribba B, Sela M, Possinger K, Yarden Y (2011) Simultaneous inhibition of estrogen receptor and the HER2 pathway in breast cancer: effects of HER2 abundance. Transl Oncol 4:293-300
    • (2011) Transl Oncol , vol.4 , pp. 293-300
    • Emde, A.1    Mahlknecht, G.2    Maslak, K.3    Ribba, B.4    Sela, M.5    Possinger, K.6    Yarden, Y.7
  • 11
    • 34548537574 scopus 로고    scopus 로고
    • A phase II placebo-controlled trial of neoadjuvant anastrozole alone or with gefitinib in early breast cancer
    • 17679728 10.1200/JCO.2006.09.6578 1:CAS:528:DC%2BD2sXhtFanu7zJ
    • Smith IE, Walsh G, Skene A, Llombart A, Mayordomo JI, Detre S, Salter J, Clark E, Magill P, Dowsett M (2007) A phase II placebo-controlled trial of neoadjuvant anastrozole alone or with gefitinib in early breast cancer. J Clin Oncol 25:3816-3822
    • (2007) J Clin Oncol , vol.25 , pp. 3816-3822
    • Smith, I.E.1    Walsh, G.2    Skene, A.3    Llombart, A.4    Mayordomo, J.I.5    Detre, S.6    Salter, J.7    Clark, E.8    Magill, P.9    Dowsett, M.10
  • 13
    • 84863717166 scopus 로고    scopus 로고
    • A randomized trial of combination anastrozole plus gefitinib and of combination fulvestrant plus gefitinib in the treatment of postmenopausal women with hormone receptor positive metastatic breast cancer
    • 22418699 10.1007/s10549-012-1997-5 1:CAS:528:DC%2BC38XpvFeqsLY%3D
    • Carlson RW, O'Neill A, Vidaurre T, Gomez HL, Badve SS, Sledge GW (2012) A randomized trial of combination anastrozole plus gefitinib and of combination fulvestrant plus gefitinib in the treatment of postmenopausal women with hormone receptor positive metastatic breast cancer. Breast Cancer Res Treat 133(3):1049-1056
    • (2012) Breast Cancer Res Treat , vol.133 , Issue.3 , pp. 1049-1056
    • Carlson, R.W.1    O'Neill, A.2    Vidaurre, T.3    Gomez, H.L.4    Badve, S.S.5    Sledge, G.W.6
  • 14
    • 75549083827 scopus 로고    scopus 로고
    • EGFR signaling and drug discovery
    • 20130423 10.1159/000279388 1:CAS:528:DC%2BC3cXit1Ont70%3D
    • Lurje G, Lenz HJ (2009) EGFR signaling and drug discovery. Oncology 77:400-410
    • (2009) Oncology , vol.77 , pp. 400-410
    • Lurje, G.1    Lenz, H.J.2
  • 15
    • 70449534597 scopus 로고    scopus 로고
    • EGFR ligands and their signaling scissors, ADAMs, as new molecular targets for anticancer treatments
    • 19896805 10.1016/j.jdermsci.2009.10.002 1:CAS:528:DC%2BD1MXhsVGlt77L
    • Kataoka H (2009) EGFR ligands and their signaling scissors, ADAMs, as new molecular targets for anticancer treatments. J Dermatol Sci 56:148-153
    • (2009) J Dermatol Sci , vol.56 , pp. 148-153
    • Kataoka, H.1
  • 16
    • 22144431886 scopus 로고    scopus 로고
    • Autocrine, paracrine and juxtacrine signaling by EGFR ligands
    • 15982853 10.1016/j.cellsig.2005.03.026 1:CAS:528:DC%2BD2MXmsVOns70%3D
    • Singh AB, Harris RC (2005) Autocrine, paracrine and juxtacrine signaling by EGFR ligands. Cell Signal 17:1183-1193
    • (2005) Cell Signal , vol.17 , pp. 1183-1193
    • Singh, A.B.1    Harris, R.C.2
  • 17
    • 0034987631 scopus 로고    scopus 로고
    • Enhanced epidermal growth factor receptor signaling in MCF7 breast cancer cells after long-term culture in the presence of the pure antiestrogen ICI 182,780 (Faslodex)
    • 11415996 10.1210/en.142.7.2776 1:CAS:528:DC%2BD3MXkslels7o%3D
    • McClelland RA, Barrow D, Madden TA, Dutkowski CM, Pamment J, Knowlden JM, Gee JM, Nicholson RI (2001) Enhanced epidermal growth factor receptor signaling in MCF7 breast cancer cells after long-term culture in the presence of the pure antiestrogen ICI 182,780 (Faslodex). Endocrinology 142:2776-2788
    • (2001) Endocrinology , vol.142 , pp. 2776-2788
    • McClelland, R.A.1    Barrow, D.2    Madden, T.A.3    Dutkowski, C.M.4    Pamment, J.5    Knowlden, J.M.6    Gee, J.M.7    Nicholson, R.I.8
  • 18
    • 33748068094 scopus 로고    scopus 로고
    • Mechanisms of tumor regression and resistance to estrogen deprivation and fulvestrant in a model of estrogen receptor-positive, HER-2/neu-positive breast cancer
    • 16912207 10.1158/0008-5472.CAN-05-4045 1:CAS:528:DC%2BD28XotFWqurs%3D
    • Massarweh S, Osborne CK, Jiang S, Wakeling AE, Rimawi M, Mohsin SK, Hilsenbeck S, Schiff R (2006) Mechanisms of tumor regression and resistance to estrogen deprivation and fulvestrant in a model of estrogen receptor-positive, HER-2/neu-positive breast cancer. Cancer Res 66:8266-8273
    • (2006) Cancer Res , vol.66 , pp. 8266-8273
    • Massarweh, S.1    Osborne, C.K.2    Jiang, S.3    Wakeling, A.E.4    Rimawi, M.5    Mohsin, S.K.6    Hilsenbeck, S.7    Schiff, R.8
  • 19
    • 39049175084 scopus 로고    scopus 로고
    • Cooperative effect of gefitinib and fumitremorgin c on cell growth and chemosensitivity in estrogen receptor alpha negative fulvestrant-resistant MCF-7 cells
    • 17016657 1:CAS:528:DC%2BD28Xht1Wjs7jP
    • Liu H, Cheng D, Weichel AK, Osipo C, Wing LK, Chen B, Louis TE, Jordan VC (2006) Cooperative effect of gefitinib and fumitremorgin c on cell growth and chemosensitivity in estrogen receptor alpha negative fulvestrant-resistant MCF-7 cells. Int J Oncol 29:1237-1246
    • (2006) Int J Oncol , vol.29 , pp. 1237-1246
    • Liu, H.1    Cheng, D.2    Weichel, A.K.3    Osipo, C.4    Wing, L.K.5    Chen, B.6    Louis, T.E.7    Jordan, V.C.8
  • 21
    • 77953119642 scopus 로고    scopus 로고
    • Breast cancer cells can switch between estrogen receptor alpha and ErbB signaling and combined treatment against both signaling pathways postpones development of resistance
    • 19697122 10.1007/s10549-009-0506-y 1:CAS:528:DC%2BC3cXmtVyrtr0%3D
    • Sonne-Hansen K, Norrie IC, Emdal KB, Benjaminsen RV, Frogne T, Christiansen IJ, Kirkegaard T, Lykkesfeldt AE (2010) Breast cancer cells can switch between estrogen receptor alpha and ErbB signaling and combined treatment against both signaling pathways postpones development of resistance. Breast Cancer Res Treat 121:601-613
    • (2010) Breast Cancer Res Treat , vol.121 , pp. 601-613
    • Sonne-Hansen, K.1    Norrie, I.C.2    Emdal, K.B.3    Benjaminsen, R.V.4    Frogne, T.5    Christiansen, I.J.6    Kirkegaard, T.7    Lykkesfeldt, A.E.8
  • 22
    • 0742304062 scopus 로고    scopus 로고
    • Motility response to insulin-like growth factor-I (IGF-I) in MCF-7 cells is associated with IRS-2 activation and integrin expression
    • 14997047 10.1023/B:BREA.0000010709.31256.c6 1:CAS:528:DC%2BD2cXnvVKh
    • Zhang X, Kamaraju S, Hakuno F, Kabuta T, Takahashi S, Sachdev D, Yee D (2004) Motility response to insulin-like growth factor-I (IGF-I) in MCF-7 cells is associated with IRS-2 activation and integrin expression. Breast Cancer Res Treat 83:161-170
    • (2004) Breast Cancer Res Treat , vol.83 , pp. 161-170
    • Zhang, X.1    Kamaraju, S.2    Hakuno, F.3    Kabuta, T.4    Takahashi, S.5    Sachdev, D.6    Yee, D.7
  • 23
    • 33750453743 scopus 로고    scopus 로고
    • Insulin receptor substrates mediate distinct biological responses to insulin-like growth factor receptor activation in breast cancer cells
    • 17043687 10.1038/sj.bjc.6603354 1:CAS:528:DC%2BD28XhtFChs7zN
    • Byron SA, Horwitz KB, Richer JK, Lange CA, Zhang X, Yee D (2006) Insulin receptor substrates mediate distinct biological responses to insulin-like growth factor receptor activation in breast cancer cells. Br J Cancer 95:1220-1228
    • (2006) Br J Cancer , vol.95 , pp. 1220-1228
    • Byron, S.A.1    Horwitz, K.B.2    Richer, J.K.3    Lange, C.A.4    Zhang, X.5    Yee, D.6
  • 24
    • 0035423119 scopus 로고    scopus 로고
    • Re-expression of estrogen receptor alpha in estrogen receptor alpha-negative MCF-7 cells restores both estrogen and insulin-like growth factor-mediated signaling and growth
    • 11479214 1:CAS:528:DC%2BD3MXlvVCgtbw%3D
    • Oesterreich S, Zhang P, Guler RL, Sun X, Curran EM, Welshons WV, Osborne CK, Lee AV (2001) Re-expression of estrogen receptor alpha in estrogen receptor alpha-negative MCF-7 cells restores both estrogen and insulin-like growth factor-mediated signaling and growth. Cancer Res 61:5771-5777
    • (2001) Cancer Res , vol.61 , pp. 5771-5777
    • Oesterreich, S.1    Zhang, P.2    Guler, R.L.3    Sun, X.4    Curran, E.M.5    Welshons, W.V.6    Osborne, C.K.7    Lee, A.V.8
  • 25
    • 77649268890 scopus 로고    scopus 로고
    • Inhibitors of the PI3K/Akt/mTOR pathway: New hope for breast cancer patients
    • 19751211 10.2174/157489210789702208 1:CAS:528:DC%2BC3cXisVKmtLk%3D
    • Ghayad SE, Cohen PA (2010) Inhibitors of the PI3K/Akt/mTOR pathway: new hope for breast cancer patients. Recent Pat Anticancer Drug Discov 5:29-57
    • (2010) Recent Pat Anticancer Drug Discov , vol.5 , pp. 29-57
    • Ghayad, S.E.1    Cohen, P.A.2
  • 26
    • 25844490097 scopus 로고    scopus 로고
    • Endocrinology and hormone therapy in breast cancer: New insight into estrogen receptor-alpha function and its implication for endocrine therapy resistance in breast cancer
    • 16168139 10.1186/bcr1287 1:CAS:528:DC%2BD2MXpvFOgt7c%3D
    • Schiff R, Osborne CK (2005) Endocrinology and hormone therapy in breast cancer: new insight into estrogen receptor-alpha function and its implication for endocrine therapy resistance in breast cancer. Breast Cancer Res 7:205-211
    • (2005) Breast Cancer Res , vol.7 , pp. 205-211
    • Schiff, R.1    Osborne, C.K.2
  • 27
    • 42049121934 scopus 로고    scopus 로고
    • Crosstalk between the estrogen receptor and the HER tyrosine kinase receptor family: Molecular mechanism and clinical implications for endocrine therapy resistance
    • 18216219 10.1210/er.2006-0045 1:CAS:528:DC%2BD1cXltlOhsrk%3D
    • Arpino G, Wiechmann L, Osborne CK, Schiff R (2008) Crosstalk between the estrogen receptor and the HER tyrosine kinase receptor family: molecular mechanism and clinical implications for endocrine therapy resistance. Endocr Rev 29:217-233
    • (2008) Endocr Rev , vol.29 , pp. 217-233
    • Arpino, G.1    Wiechmann, L.2    Osborne, C.K.3    Schiff, R.4
  • 28
    • 0033429237 scopus 로고    scopus 로고
    • Acquired antiestrogen resistance in MCF-7 human breast cancer sublines is not accomplished by altered expression of receptors in the ErbB-family
    • 10634517 10.1023/A:1006232830161 1:CAS:528:DC%2BD3cXmsV2htA%3D%3D
    • Larsen SS, Egeblad M, Jaattela M, Lykkesfeldt AE (1999) Acquired antiestrogen resistance in MCF-7 human breast cancer sublines is not accomplished by altered expression of receptors in the ErbB-family. Breast Cancer Res Treat 58:41-56
    • (1999) Breast Cancer Res Treat , vol.58 , pp. 41-56
    • Larsen, S.S.1    Egeblad, M.2    Jaattela, M.3    Lykkesfeldt, A.E.4
  • 29
    • 0029916220 scopus 로고    scopus 로고
    • Short-term effects of pure anti-oestrogen ICI 182780 treatment on oestrogen receptor, epidermal growth factor receptor and transforming growth factor-alpha protein expression in human breast cancer
    • 8814683 10.1016/0959-8049(95)00517-X 1:CAS:528:DyaK28XisFyitLg%3D
    • McClelland RA, Gee JM, Francis AB, Robertson JF, Blamey RW, Wakeling AE, Nicholson RI (1996) Short-term effects of pure anti-oestrogen ICI 182780 treatment on oestrogen receptor, epidermal growth factor receptor and transforming growth factor-alpha protein expression in human breast cancer. Eur J Cancer 32A:413-416
    • (1996) Eur J Cancer , vol.32 , pp. 413-416
    • McClelland, R.A.1    Gee, J.M.2    Francis, A.B.3    Robertson, J.F.4    Blamey, R.W.5    Wakeling, A.E.6    Nicholson, R.I.7
  • 30
    • 1242338758 scopus 로고    scopus 로고
    • Selective estrogen receptor modulators: Discrimination of agonistic versus antagonistic activities by gene expression profiling in breast cancer cells
    • 14973112 10.1158/0008-5472.CAN-03-3326 1:CAS:528:DC%2BD2cXhtleitLk%3D
    • Frasor J, Stossi F, Danes JM, Komm B, Lyttle CR, Katzenellenbogen BS (2004) Selective estrogen receptor modulators: discrimination of agonistic versus antagonistic activities by gene expression profiling in breast cancer cells. Cancer Res 64:1522-1533
    • (2004) Cancer Res , vol.64 , pp. 1522-1533
    • Frasor, J.1    Stossi, F.2    Danes, J.M.3    Komm, B.4    Lyttle, C.R.5    Katzenellenbogen, B.S.6
  • 31
    • 1542344018 scopus 로고    scopus 로고
    • Estradiol and selective estrogen receptor modulators differentially regulate target genes with estrogen receptors alpha and beta
    • 14699072 1:CAS:528:DC%2BD2cXitlGgs74%3D
    • Tee MK, Rogatsky I, Tzagarakis-Foster C, Cvoro A, An J, Christy RJ, Yamamoto KR, Leitman DC (2004) Estradiol and selective estrogen receptor modulators differentially regulate target genes with estrogen receptors alpha and beta. Mol Biol Cell 15:1262-1272
    • (2004) Mol Biol Cell , vol.15 , pp. 1262-1272
    • Tee, M.K.1    Rogatsky, I.2    Tzagarakis-Foster, C.3    Cvoro, A.4    An, J.5    Christy, R.J.6    Yamamoto, K.R.7    Leitman, D.C.8
  • 32
    • 2342526570 scopus 로고    scopus 로고
    • Estrogen regulation in human breast cancer cells of new downstream gene targets involved in estrogen metabolism, cell proliferation and cell transformation
    • 15072547 10.1677/jme.0.0320397 1:CAS:528:DC%2BD2cXjslKjtrY%3D
    • Vendrell JA, Magnino F, Danis E, Duchesne MJ, Pinloche S, Pons M, Birnbaum D, Nguyen C, Theillet C, Cohen PA (2004) Estrogen regulation in human breast cancer cells of new downstream gene targets involved in estrogen metabolism, cell proliferation and cell transformation. J Mol Endocrinol 32:397-414
    • (2004) J Mol Endocrinol , vol.32 , pp. 397-414
    • Vendrell, J.A.1    Magnino, F.2    Danis, E.3    Duchesne, M.J.4    Pinloche, S.5    Pons, M.6    Birnbaum, D.7    Nguyen, C.8    Theillet, C.9    Cohen, P.A.10
  • 33
    • 25844509287 scopus 로고    scopus 로고
    • Analysis of estrogen agonism and antagonism of tamoxifen, raloxifene, and ICI182780 in endometrial cancer cells: A putative role for the epidermal growth factor receptor ligand amphiregulin
    • 16202921 10.1016/j.jsgi.2005.08.003
    • Gielen SC, Burger CW, Kuhne LC, Hanifi-Moghaddam P, Blok LJ (2005) Analysis of estrogen agonism and antagonism of tamoxifen, raloxifene, and ICI182780 in endometrial cancer cells: a putative role for the epidermal growth factor receptor ligand amphiregulin. J Soc Gynecol Investig 12:e55-e67
    • (2005) J Soc Gynecol Investig , vol.12
    • Gielen, S.C.1    Burger, C.W.2    Kuhne, L.C.3    Hanifi-Moghaddam, P.4    Blok, L.J.5
  • 34
    • 79961011383 scopus 로고    scopus 로고
    • Fulvestrant-induced expression of ErbB3 and ErbB4 receptors sensitizes oestrogen receptor-positive breast cancer cells to heregulin beta1
    • 21396094 10.1186/bcr2848 1:CAS:528:DC%2BC3MXksVyjs7o%3D
    • Hutcheson IR, Goddard L, Barrow D, McClelland RA, Francies HE, Knowlden JM, Nicholson RI, Gee JM (2011) Fulvestrant-induced expression of ErbB3 and ErbB4 receptors sensitizes oestrogen receptor-positive breast cancer cells to heregulin beta1. Breast Cancer Res 13:R29
    • (2011) Breast Cancer Res , vol.13 , pp. 29
    • Hutcheson, I.R.1    Goddard, L.2    Barrow, D.3    McClelland, R.A.4    Francies, H.E.5    Knowlden, J.M.6    Nicholson, R.I.7    Gee, J.M.8
  • 35
    • 70450236961 scopus 로고    scopus 로고
    • The NRG1 gene is frequently silenced by methylation in breast cancers and is a strong candidate for the 8p tumour suppressor gene
    • 19802002 10.1038/onc.2009.259 1:CAS:528:DC%2BD1MXht1Wgsb3J
    • Chua YL, Ito Y, Pole JC, Newman S, Chin SF, Stein RC, Ellis IO, Caldas C, O'Hare MJ, Murrell A, Edwards PA (2009) The NRG1 gene is frequently silenced by methylation in breast cancers and is a strong candidate for the 8p tumour suppressor gene. Oncogene 28:4041-4052
    • (2009) Oncogene , vol.28 , pp. 4041-4052
    • Chua, Y.L.1    Ito, Y.2    Pole, J.C.3    Newman, S.4    Chin, S.F.5    Stein, R.C.6    Ellis, I.O.7    Caldas, C.8    O'Hare, M.J.9    Murrell, A.10    Edwards, P.A.11
  • 36
    • 0037562684 scopus 로고    scopus 로고
    • MRNA expression of the type i growth factor receptors in the human breast cancer cells MCF-7: Regulation by estradiol and tamoxifen
    • 12820409 1:CAS:528:DC%2BD3sXltlGmtb0%3D
    • Revillion F, Pawlowski V, Lhotellier V, Louchez MM, Peyrat JP (2003) mRNA expression of the type I growth factor receptors in the human breast cancer cells MCF-7: regulation by estradiol and tamoxifen. Anticancer Res 23:1455-1460
    • (2003) Anticancer Res , vol.23 , pp. 1455-1460
    • Revillion, F.1    Pawlowski, V.2    Lhotellier, V.3    Louchez, M.M.4    Peyrat, J.P.5
  • 37
    • 33645730357 scopus 로고    scopus 로고
    • Activation of mitogen-activated protein kinase in estrogen receptor alpha-positive breast cancer cells in vitro induces an in vivo molecular phenotype of estrogen receptor alpha-negative human breast tumors
    • 16585219 10.1158/0008-5472.CAN-05-4363 1:CAS:528:DC%2BD28XjtVOqs74%3D
    • Creighton CJ, Hilger AM, Murthy S, Rae JM, Chinnaiyan AM, El-Ashry D (2006) Activation of mitogen-activated protein kinase in estrogen receptor alpha-positive breast cancer cells in vitro induces an in vivo molecular phenotype of estrogen receptor alpha-negative human breast tumors. Cancer Res 66:3903-3911
    • (2006) Cancer Res , vol.66 , pp. 3903-3911
    • Creighton, C.J.1    Hilger, A.M.2    Murthy, S.3    Rae, J.M.4    Chinnaiyan, A.M.5    El-Ashry, D.6
  • 38
    • 77950691767 scopus 로고    scopus 로고
    • Estrogen receptor alpha attenuates transforming growth factor-beta signaling in breast cancer cells independent from agonistic and antagonistic ligands
    • 19370415 10.1007/s10549-009-0393-2 1:CAS:528:DC%2BC3cXjtlahuro%3D
    • Stope MB, Popp SL, Knabbe C, Buck MB (2010) Estrogen receptor alpha attenuates transforming growth factor-beta signaling in breast cancer cells independent from agonistic and antagonistic ligands. Breast Cancer Res Treat 120:357-367
    • (2010) Breast Cancer Res Treat , vol.120 , pp. 357-367
    • Stope, M.B.1    Popp, S.L.2    Knabbe, C.3    Buck, M.B.4
  • 39
    • 66149102496 scopus 로고    scopus 로고
    • ERalpha as ligand-independent activator of CDH-1 regulates determination and maintenance of epithelial morphology in breast cancer cells
    • 19383788 10.1073/pnas.0903033106 1:CAS:528:DC%2BD1MXmt1Khtr4%3D
    • Cardamone MD, Bardella C, Gutierrez A, Di Croce L, Rosenfeld MG, Di Renzo MF, De Bortoli M (2009) ERalpha as ligand-independent activator of CDH-1 regulates determination and maintenance of epithelial morphology in breast cancer cells. Proc Natl Acad Sci USA 106:7420-7425
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 7420-7425
    • Cardamone, M.D.1    Bardella, C.2    Gutierrez, A.3    Di Croce, L.4    Rosenfeld, M.G.5    Di Renzo, M.F.6    De Bortoli, M.7
  • 41
    • 60749137227 scopus 로고    scopus 로고
    • Modification of gene expression induced by siRNA targeting of estrogen receptor alpha in MCF7 human breast cancer cells
    • 19082494 1:CAS:528:DC%2BD1MXht1Cqtr0%3D
    • Luqmani YA, Al Azmi A, Al Bader M, Abraham G, El Zawahri M (2009) Modification of gene expression induced by siRNA targeting of estrogen receptor alpha in MCF7 human breast cancer cells. Int J Oncol 34:231-242
    • (2009) Int J Oncol , vol.34 , pp. 231-242
    • Luqmani, Y.A.1    Al Azmi, A.2    Al Bader, M.3    Abraham, G.4    El Zawahri, M.5
  • 42
    • 62549121734 scopus 로고    scopus 로고
    • Anti-oestrogens but not oestrogen deprivation promote cellular invasion in intercellular adhesion-deficient breast cancer cells
    • 19055788 10.1186/bcr2206
    • Borley AC, Hiscox S, Gee J, Smith C, Shaw V, Barrett-Lee P, Nicholson RI (2008) Anti-oestrogens but not oestrogen deprivation promote cellular invasion in intercellular adhesion-deficient breast cancer cells. Breast Cancer Res 10:R103
    • (2008) Breast Cancer Res , vol.10 , pp. 103
    • Borley, A.C.1    Hiscox, S.2    Gee, J.3    Smith, C.4    Shaw, V.5    Barrett-Lee, P.6    Nicholson, R.I.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.