Tempol prevents cardiac oxidative damage and left ventricular dysfunction in the PPAR-α KO mouse

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 304, Issue 11, 2013, Pages

  Guellich, Aziz ^a   Damy, Thibaud ^b,c,d   Conti, Marc ^b   Claes, Victor ^e   Samuel, Jane Lise ^a   Pineau, Thierry ^f   Lecarpentier, Yves ^g,h   Coirault, Catherine ^a,i,j,k  

^a INSERM   (France)

^b HENRI MONDOR HOSPITAL   (France)

^c INSERM U955   (France)

^d UNIVERSITÉ PARIS EST CRÉTEIL   (France)

^e UNIVERSITY OF ANTWERP   (Belgium)

^f CEMAGREF   (France)

^g PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^h CENTRE HOSPITALIER DE MEAUX   (France)

ⁱ CNRS   (France)

^j SORBONNE UNIVERSITÉ   (France)

^k Institut de Myologie   (France)

more..

Author keywords

Antioxidant therapy; Cardiomyopathy; Knockout; Metabolism; Myosin; Oxidative stress; Peroxisome proliferator activated receptor

Indexed keywords

ANION; ANION SUPEROXIDE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; MYOSIN HEAVY CHAIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; TEMPOL; TYROSINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERIAL PRESSURE; ARTICLE; DRUG MECHANISM; ECHOCARDIOGRAPHY; ENZYME ACTIVITY; HEART INJURY; HEART LEFT VENTRICLE CONTRACTILITY; HEART LEFT VENTRICLE EJECTION FRACTION; HEART LEFT VENTRICLE FAILURE; HEART LEFT VENTRICLE FUNCTION; HEART PAPILLARY MUSCLE; IN VIVO STUDY; MALE; MOUSE; NITRATION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROPHYLAXIS; PROTEIN EXPRESSION;

ANTIOXIDANT THERAPY; CARDIOMYOPATHY; KNOCKOUT; METABOLISM; MYOSIN; OXIDATIVE STRESS; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-Α;

ANIMALS; ARTERIAL PRESSURE; BLOOD PRESSURE; BLOTTING, WESTERN; CYCLIC N-OXIDES; ECHOCARDIOGRAPHY; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GLUCOSEPHOSPHATE DEHYDROGENASE; ISOMERISM; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MYOCARDIAL CONTRACTION; MYOCARDIUM; MYOSIN HEAVY CHAINS; OXIDATIVE STRESS; PAPILLARY MUSCLES; PPAR ALPHA; SPIN LABELS; SUPEROXIDE DISMUTASE; VENTRICULAR DYSFUNCTION, LEFT;

EID: 84878752153     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00669.2012     Document Type: Article

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