Cytotoxicity of hydroxyapatite nanoparticles is shape and cell dependent

Archives of Toxicology

Volumn 87, Issue 6, 2013, Pages 1037-1052

  Zhao, Xinxin ^a   Ng, Suxiu ^a   Heng, Boon Chin ^a   Guo, Jun ^a   Ma, Lwinlwin ^a   Tan, Timothy Thatt Yang ^b   Ng, Kee Woei ^a   Loo, Say Chye Joachim ^a  

^a NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

^b Nanyang Technological University   (Singapore)

Author keywords

Hydroxyapatite; Inflammatory cytokines; Nanomaterials; Nanotoxicity; Particle cell association

Indexed keywords

FLUORESCEIN ISOTHIOCYANATE; HYDROXYAPATITE; INTERLEUKIN 6; NANOPARTICLE; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; BRONCHUS MUCOSA; CELL DEATH; CELL STRAIN BEAS 2B; CELL STRAIN RAW264.7; CHEMICAL COMPOSITION; CONCENTRATION (PARAMETERS); CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; CRYSTAL STRUCTURE; CYTOKINE PRODUCTION; CYTOTOXICITY; EPITHELIUM CELL; EXPOSURE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; MACROPHAGE; MOUSE; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; SYNTHESIS;

ANIMALS; APOPTOSIS; CELL LINE; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DURAPATITE; EPITHELIAL CELLS; HUMANS; INFLAMMATION MEDIATORS; INTERLEUKIN-6; LUNG; MACROPHAGES; MICE; MOLECULAR CONFORMATION; NANOPARTICLES; NECROSIS; OXIDATIVE STRESS; PARTICLE SIZE; REACTIVE OXYGEN SPECIES; SURFACE PROPERTIES; TIME FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84878728449     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-012-0827-1     Document Type: Article

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