Mass spectrometry identification of granins and other proteins secreted by neuroblastoma cells

Tumor Biology

Volumn 34, Issue 3, 2013, Pages 1773-1781

  Rozek, Wojciech ^a   Kwasnik, Malgorzata ^a   Debski, Janusz ^b   Zmudzinski, Jan F ^a  

^a NATIONAL VETERINARY RESEARCH INSTITUTE   (Poland)

^b INSTITUTE OF BIOCHEMISTRY AND BIOPHYSICS   (Poland)

Author keywords

Chromogranin; Granins; Neuroblastoma; Secretogranin; Secretome

Indexed keywords

CHROMOGRANIN A; CHROMOGRANIN B; PEPTIDES AND PROTEINS; PROTEOME; SECRETOGRANIN III; SECRETOME; UNCLASSIFIED DRUG; VGF NERVE GROWTH FACTOR INDUCIBLE PROTEIN;

AMINO ACID SEQUENCE; ANGIOGENESIS; ANIMAL CELL; APOPTOSIS; ARTICLE; BIOLOGICAL ACTIVITY; CELL ADHESION; CELL CYCLE REGULATION; CELL PROLIFERATION; ENDOPLASMIC RETICULUM; MASS SPECTROMETRY; MOUSE; NEUROBLASTOMA CELL; NONHUMAN; PEPTIDE ANALYSIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DETERMINATION; PROTEIN FUNCTION; PROTEIN SECRETION; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION;

EID: 84878723809     PISSN: 10104283     EISSN: 14230380     Source Type: Journal    
DOI: 10.1007/s13277-013-0716-0     Document Type: Article

References (56)

1. Aardal S, Helle KB. The vasoinhibitory activity of bovine chromogranin A fragment (vasostatin) and its independence of extracellular calcium in isolated segments of human blood vessels. Regul Pept. 1992;41(1):9-18.
2. Apweiler R, Bairoch A, Wu CH, Barker WC, Boeckmann B, Ferro S, Gasteiger E, Huang H, Lopez R, Magrane M, Martin MJ, Natale DA, O'Donovan C, Redaschi N, Yeh, LS (2004) UniProt: the Universal Protein knowledgebase. Nucleic Acids Res 32(Database issue): D115-9.
3. Ashburner M, Ball CA, Blake JA, Botstein D, Butler H, Cherry JM, et al. Gene ontology: tool for the unification of biology. The Gene Ontology Consortium. Nat Genet. 2000;25(1):25-9.
4. Bartolomucci A, Bresciani E, Bulgarelli I, Rigamonti AE, Pascucci T, Levi A, et al. Chronic intracerebroventricular injection of TLQP-21 prevents high fat diet induced weight gain in fast weight-gaining mice. Genes Nutr. 2009;4(1):49-57.
5. Bartolomucci A, La Corte G, Possenti R, Locatelli V, Rigamonti AE, Torsello A, et al. TLQP-21, a VGF-derived peptide, increases energy expenditure and prevents the early phase of diet-induced obesity. Proc Natl Acad Sci U S A. 2006;103(39):14584-9.
6. Bartolomucci A, Pasinetti GM, Salton SR. Granins as disease-biomarkers: translational potential for psychiatric and neurological disorders. Neuroscience. 2010;170(1):289-97.
7. Bartolomucci A, Possenti R, Mahata SK, Fischer-Colbrie R, Loh YP, Salton SR. The extended granin family: structure, function, and biomedical implications. Endocr Rev. 2011;32(6):755-97.
8. Bendtsen JD, Jensen LJ, Blom N, Von Heijne G, Brunak S. Feature-based prediction of non-classical and leaderless protein secretion. Protein Eng Des Sel. 2004;17(4):349-56.
9. Chenau J, Michelland S, de Fraipont F, Josserand V, Coll JL, Favrot MC, et al. The cell line secretome, a suitable tool for investigating proteins released in vivo by tumors: application to the study of p53-modulated proteins secreted in lung cancer cells. J Proteome Res. 2009;8(10):4579-91.
10. Cocco C, D'Amato F, Noli B, Ledda A, Brancia C, Bongioanni P, et al. Distribution of VGF peptides in the human cortex and their selective changes in Parkinson's and Alzheimer's diseases. J Anat. 2010;217(6):683-93.
11. Conlon JM. Granin-derived peptides as diagnostic and prognostic markers for endocrine tumors. Regul Pept. 2010;165(1):5-11.
12. Curry WJ, Johnston CF, Hutton JC, Arden SD, Rutherford NG, Shaw C, et al. The tissue distribution of rat chromogranin A-derived peptides: evidence for differential tissue processing from sequence specific antisera. Histochemistry. 1991;96(6):531-8.
13. D'Amato F, Cocco C, Noli B, Cabras T, Messana I, Ferri GL. VGF peptides upon osmotic stimuli: changes in neuroendocrine regulatory peptides 1 and 2 in the hypothalamic-pituitary-axis and plasma. J Chem Neuroanat. 2012;44(2):57-65.
14. Doucet A, Butler GS, Rodriguez D, Prudova A, Overall CM. Metadegradomics: toward in vivo quantitative degradomics of proteolytic post-translational modifications of the cancer proteome. Mol Cell Proteomics. 2008;7(10):1925-51.
15. Fricker LD, McKinzie AA, Sun J, Curran E, Qian Y, Yan L, et al. Identification and characterization of proSAAS, a granin-like neuroendocrine peptide precursor that inhibits prohormone processing. J Neurosci. 2000;20(2):639-48.
16. Guerin M, Guillemot J, Thouennon E, Pierre A, El-Yamani FZ, Montero-Hadjadje M, et al. Granins and their derived peptides in normal and tumoral chromaffin tissue: implications for the diagnosis and prognosis of pheochromocytoma. Regul Pept. 2010;165(1):21-9.
17. Hann HW, Stahlhut MW, Evans AE. Serum ferritin as a prognostic indicator in neuroblastoma: biological effects of isoferritins. Prog Clin Biol Res. 1985;175:331-45.
18. Helle KB. The granin family of uniquely acidic proteins of the diffuse neuroendocrine system: comparative and functional aspects. Biol Rev Camb Philos Soc. 2004;79(4):769-94.
19. Helle KB. The chromogranin A-derived peptides vasostatin-I and catestatin as regulatory peptides for cardiovascular functions. Cardiovasc Res. 2010;85(1):9-16.
20. Hosaka M, Suda M, Sakai Y, Izumi T, Watanabe T, Takeuchi T. Secretogranin III binds to cholesterol in the secretory granule membrane as an adapter for chromogranin A. J Biol Chem. 2004;279(5):3627-34.
21. Hosaka M, Watanabe T, Sakai Y, Kato T, Takeuchi T. Interaction between secretogranin III and carboxypeptidase E facilitates prohormone sorting within secretory granules. J Cell Sci. 2005;118(Pt 20):4785-95.
22. Hsiao RJ, Seeger RC, Yu AL, O'Connor DT. Chromogranin A in children with neuroblastoma. Serum concentration parallels disease stage and predicts survival. J Clin Invest. 1990;85(5):1555-9.
23. Jethwa PH, Ebling FJ. Role of VGF-derived peptides in the control of food intake, body weight and reproduction. Neuroendocrinology. 2008;88(2):80-7.
24. Karagiannis GS, Pavlou MP, Diamandis EP. Cancer secretomics reveal pathophysiological pathways in cancer molecular oncology. Mol Oncol. 2010;4(6):496-510.
25. Kogner P, Bjellerup P, Svensson T, Theodorsson E. Pancreastatin immunoreactivity in favourable childhood neuroblastoma and ganglioneuroma. Eur J Cancer. 1995;31A(4):557-60.
26. Koshimizu H, Cawley NX, Kim T, Yergey AL, Loh YP. Serpinin: a novel chromogranin A-derived, secreted peptide up-regulates protease nexin-1 expression and granule biogenesis in endocrine cells. Mol Endocrinol. 2011;25(5):732-44.
27. Kroesen S, Marksteiner J, Leitner B, Hogue-Angeletti R, Fischer-Colbrie R, Winkler H. Rat brain: distribution of immunoreactivity of PE-11, a peptide derived from chromogranin B. Eur J Neurosci. 1996;8(12):2679-89.
28. Kruger PG, Mahata SK, Helle KB. Catestatin (CgA344-364) stimulates rat mast cell release of histamine in a manner comparable to mastoparan and other cationic charged neuropeptides. Regul Pept. 2003;114(1):29-35.
29. Kwasnik M, Rozek W, Zmudzinski JF. Different patterns of multiplication of equine influenza virus serotypes H7N7 and H3N8 in chicken embryo. Bull Vet Inst Pulawy. 2011;55(4):575-9.
30. Loh YP, Cheng Y, Mahata SK, Corti A, Tota B. Chromogranin a and derived peptides in health and disease. J Mol Neurosci. 2012;48(2):347-56.
31. Loh YP, Koshimizu H, Cawley NX, Tota B. Serpinins: role in granule biogenesis, inhibition of cell death and cardiac function. Curr Med Chem. 2012;19(24):4086-92.
32. Machado JD, Diaz-Vera J, Dominguez N, Alvarez CM, Pardo MR, Borges R. Chromogranins A and B as regulators of vesicle cargo and exocytosis. Cell Mol Neurobiol. 2010;30(8):1181-7.
33. Makridakis M, Vlahou A. Secretome proteomics for discovery of cancer biomarkers. J Proteomics. 2010;73(12):2291-305.
34. McVicar CM, Cunningham RT, Harriott P, Johnston CF, Buchanan KD, Curry WJ. Analysis of the post-translational processing of chromogranin A in rat neuroendocrine tissue employing an N-terminal site-specific antiserum. J Neuroendocrinol. 2001;13(7):588-95.
35. Mehul B, Hughes RC. Plasma membrane targeting, vesicular budding and release of galectin 3 from the cytoplasm of mammalian cells during secretion. J Cell Sci. 1997;110(Pt 10):1169-78.
36. Mi H, Dong Q, Muruganujan A, Gaudet P, Lewis S, Thomas PD (2010) PANTHER version 7: improved phylogenetic trees, orthologs and collaboration with the Gene Ontology Consortium. Nucleic Acids Res 38(Database issue), D204-10.
37. Pasinetti GM, Ungar LH, Lange DJ, Yemul S, Deng H, Yuan X, et al. Identification of potential CSF biomarkers in ALS. Neurology. 2006;66(8):1218-22.
38. Portela-Gomes GM, Grimelius L, Stridsberg M. Secretogranin III in human neuroendocrine tumours: a comparative immunohistochemical study with chromogranins A and B and secretogranin II. Regul Pept. 2010;165(1):30-5.
39. Portela-Gomes GM, Grimelius L, Wilander E, Stridsberg M. Granins and granin-related peptides in neuroendocrine tumours. Regul Pept. 2010;165(1):12-20.
40. Possenti R, Rinaldi AM, Ferri GL, Borboni P, Trani E, Levi A. Expression, processing, and secretion of the neuroendocrine VGF peptides by INS-1 cells. Endocrinology. 1999;140(8):3727-35.
41. Rindi G, Licini L, Necchi V, Bottarelli L, Campanini N, Azzoni C, et al. Peptide products of the neurotrophin-inducible gene vgf are produced in human neuroendocrine cells from early development and increase in hyperplasia and neoplasia. J Clin Endocrinol Metab. 2007;92(7):2811-5.
42. Rizzi R, Bartolomucci A, Moles A, D'Amato F, Sacerdote P, Levi A, et al. The VGF-derived peptide TLQP-21: a new modulatory peptide for inflammatory pain. Neurosci Lett. 2008;441(1):129-33.
43. Rossi A, Granata F, Augusti-Tocco G, Canu N, Levi A, Possenti R. Expression in murine and human neuroblastoma cell lines of VGF, a tissue specific protein. Int J Dev Neurosci. 1992;10(6):527-34.
44. Rubartelli A, Bajetto A, Allavena G, Wollman E, Sitia R. Secretion of thioredoxin by normal and neoplastic cells through a leaderless secretory pathway. J Biol Chem. 1992;267(34):24161-4.
45. Salton SR, Ferri GL, Hahm S, Snyder SE, Wilson AJ, Possenti R, et al. VGF: a novel role for this neuronal and neuroendocrine polypeptide in the regulation of energy balance. Front Neuroendocrinol. 2000;21(3):199-219.
46. Sandoval JA, Hoelz DJ, Woodruff HA, Powell RL, Jay CL, Grosfeld JL, et al. Novel peptides secreted from human neuroblastoma: useful clinical tools? J Pediatr Surg. 2006;41(1):245-51.
47. Sekiya K, Ghatei MA, Salahuddin MJ, Bishop AE, Hamid QA, Ibayashi H, et al. Production of GAWK (chromogranin-B 420-493)-like immunoreactivity by endocrine tumors and its possible diagnostic value. J Clin Invest. 1989;83(6):1834-42.
48. Strub JM, Garcia-Sablone P, Lonning K, Taupenot L, Hubert P, Van Dorsselaer A, et al. Processing of chromogranin B in bovine adrenal medulla. Identification of secretolytin, the endogenous C-terminal fragment of residues 614-626 with antibacterial activity. Eur J Biochem. 1995;229(2):356-68.
49. Thakker-Varia S, Alder J. Neuropeptides in depression: role of VGF. Behav Brain Res. 2009;197(2):262-78.
50. Thomas PD, Campbell MJ, Kejariwal A, Mi H, Karlak B, Daverman R, et al. PANTHER: a library of protein families and subfamilies indexed by function. Genome Res. 2003;13(9):2129-41.
51. Tjalsma H, Bolhuis A, Jongbloed JD, Bron S, van Dijl JM. Signal peptide-dependent protein transport in Bacillus subtilis: a genome-based survey of the secretome. Microbiol Mol Biol Rev. 2000;64(3):515-47.
52. Toshinai K, Nakazato M. Neuroendocrine regulatory peptide-1 and -2: novel bioactive peptides processed from VGF. Cell Mol Life Sci. 2009;66(11-12):1939- 45.
53. Trani E, Ciotti T, Rinaldi AM, Canu N, Ferri GL, Levi A, et al. Tissue-specific processing of the neuroendocrine protein VGF. J Neurochem. 1995;65(6):2441-9.
54. Wang Z, Vandenberghe I, Depreitere J, Devreese B, Clerens S, Nouwen EJ, et al. Identification and characterization of novel chromogranin B-derived peptides from porcine chromaffin granules by liquid chromatography/electrospray tandem MS. Eur J Biochem. 2001;268(2):235-42.
55. Zeltzer PM, Marangos PJ, Evans AE, Schneider SL. Serum neuron-specific enolase in children with neuroblastoma. Relationship to stage and disease course. Cancer. 1986;57(6):1230-4.
56. Zhao E, Zhang D, Basak A, Trudeau VL. New insights into granin-derived peptides: evolution and endocrine roles. Gen Comp Endocrinol. 2009;164(2-3):161-74.