-
1
-
-
0027921638
-
Head and neck cancer
-
Vokes EE, Weichselbaum RR, Lippman SM, and Hong WK (1993). Head and neck cancer. N Engl J Med 328, 184-194.
-
(1993)
N Engl J Med
, vol.328
, pp. 184-194
-
-
Vokes, E.E.1
Weichselbaum, R.R.2
Lippman, S.M.3
Hong, W.K.4
-
2
-
-
49249095295
-
EGFR, p16, HPV Titer, Bcl-xL and p53, sex, and smoking as indicators of response to therapy and survival in oropharyngeal cancer
-
Kumar B, Cordell KG, Lee JS, Worden FP, Prince ME, Tran HH, Wolf GT, Urba SG, Chepeha DB, Teknos TN, et al. (2008). EGFR, p16, HPV Titer, Bcl-xL and p53, sex, and smoking as indicators of response to therapy and survival in oropharyngeal cancer. J Clin Oncol 26, 3128-3137.
-
(2008)
J Clin Oncol
, vol.26
, pp. 3128-3137
-
-
Kumar, B.1
Cordell, K.G.2
Lee, J.S.3
Worden, F.P.4
Prince, M.E.5
Tran, H.H.6
Wolf, G.T.7
Urba, S.G.8
Chepeha, D.B.9
Teknos, T.N.10
-
3
-
-
0035960866
-
Head and neck cancer
-
Forastiere A, Koch W, Trotti A, and Sidransky D (2001). Head and neck cancer. N Engl J Med 345, 1890-1900.
-
(2001)
N Engl J Med
, vol.345
, pp. 1890-1900
-
-
Forastiere, A.1
Koch, W.2
Trotti, A.3
Sidransky, D.4
-
4
-
-
30444454024
-
G-protein-coupled receptors: Past, present and future
-
Hill SJ (2006). G-protein-coupled receptors: past, present and future. Br J Pharmacol 147(suppl 1), S27-S37.
-
(2006)
Br J Pharmacol
, vol.147
, Issue.SUPPL. 1
-
-
Hill, S.J.1
-
5
-
-
35948943898
-
Hypermethylation of tachykinin-1 is a potential biomarker in human esophageal cancer
-
Jin Z, Olaru A, Yang J, Sato F, Cheng Y, Kan T, Mori Y, Mantzur C, Paun B, Hamilton JP, et al. (2007). Hypermethylation of tachykinin-1 is a potential biomarker in human esophageal cancer. Clin Cancer Res 13, 6293-6300.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 6293-6300
-
-
Jin, Z.1
Olaru, A.2
Yang, J.3
Sato, F.4
Cheng, Y.5
Kan, T.6
Mori, Y.7
Mantzur, C.8
Paun, B.9
Hamilton, J.P.10
-
6
-
-
40849139208
-
Epigenetics in cancer
-
Esteller M (2008). Epigenetics in cancer. N Engl J Med 358, 1148-1159.
-
(2008)
N Engl J Med
, vol.358
, pp. 1148-1159
-
-
Esteller, M.1
-
7
-
-
0021040521
-
Galanin-a novel biologically active peptide from porcine intestine
-
Tatemoto K, Rokaeus A, Jornvall H, McDonald TJ, and Mutt V (1983). Galanin-a novel biologically active peptide from porcine intestine. FEBS Lett 164, 124-128.
-
(1983)
FEBS Lett
, vol.164
, pp. 124-128
-
-
Tatemoto, K.1
Rokaeus, A.2
Jornvall, H.3
McDonald, T.J.4
Mutt, V.5
-
9
-
-
0013641607
-
Regulatory role of galanin in control of hypothalamic-anterior pituitary function
-
Ottlecz A, Snyder GD, and McCann SM (1988). Regulatory role of galanin in control of hypothalamic-anterior pituitary function. Proc Natl Acad Sci USA 85, 9861-9865.
-
(1988)
Proc Natl Acad Sci USA
, vol.85
, pp. 9861-9865
-
-
Ottlecz, A.1
Snyder, G.D.2
McCann, S.M.3
-
10
-
-
0027358576
-
Galanin-receptor ligand M40 peptide distinguishes between putative galanin-receptor subtypes
-
Bartfai T, Langel U, Bedecs K, Andell S, Land T, Gregersen S, Ahren B, Girotti P, Consolo S, Corwin R, et al. (1993). Galanin-receptor ligand M40 peptide distinguishes between putative galanin-receptor subtypes. Proc Natl Acad Sci USA 90, 11287-11291.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 11287-11291
-
-
Bartfai, T.1
Langel, U.2
Bedecs, K.3
Andell, S.4
Land, T.5
Gregersen, S.6
Ahren, B.7
Girotti, P.8
Consolo, S.9
Corwin, R.10
-
11
-
-
17344362824
-
Cell growth control by G protein-coupled receptors: From signal transduction to signal integration
-
Gutkind JS (1998). Cell growth control by G protein-coupled receptors: from signal transduction to signal integration. Oncogene 17, 1331-1342.
-
(1998)
Oncogene
, vol.17
, pp. 1331-1342
-
-
Gutkind, J.S.1
-
12
-
-
0037066596
-
Galanin/GALP and galanin receptors: Role in central control of feeding, body weight/obesity and reproduction?
-
Gundlach AL (2002). Galanin/GALP and galanin receptors: role in central control of feeding, body weight/obesity and reproduction? Eur J Pharmacol 440, 255-268.
-
(2002)
Eur J Pharmacol
, vol.440
, pp. 255-268
-
-
Gundlach, A.L.1
-
13
-
-
20744447187
-
Galanin receptor 1 has anti-proliferative effects in oral squamous cell carcinoma
-
Henson BS, Neubig RR, Jang I, Ogawa T, Zhang Z, Carey TE, and D'Silva NJ (2005). Galanin receptor 1 has anti-proliferative effects in oral squamous cell carcinoma. J Biol Chem 280, 22564-22571.
-
(2005)
J Biol Chem
, vol.280
, pp. 22564-22571
-
-
Henson, B.S.1
Neubig, R.R.2
Jang, I.3
Ogawa, T.4
Zhang, Z.5
Carey, T.E.6
D'Silva, N.J.7
-
14
-
-
34447266723
-
Galanin and galanin receptor type 1 suppress proliferation in squamous carcinoma cells: Activation of the extracellular signal regulated kinase pathway and induction of cyclin-dependent kinase inhibitors
-
Kanazawa T, Iwashita T, Kommareddi P, Nair T, Misawa K, Misawa Y, Ueda Y, Tono T, and Carey TE (2007). Galanin and galanin receptor type 1 suppress proliferation in squamous carcinoma cells: activation of the extracellular signal regulated kinase pathway and induction of cyclin-dependent kinase inhibitors. Oncogene 26, 5762-5771.
-
(2007)
Oncogene
, vol.26
, pp. 5762-5771
-
-
Kanazawa, T.1
Iwashita, T.2
Kommareddi, P.3
Nair, T.4
Misawa, K.5
Misawa, Y.6
Ueda, Y.7
Tono, T.8
Carey, T.E.9
-
15
-
-
59449094364
-
Epigenetic inactivation of galanin receptor 1 in head and neck cancer
-
Misawa K, Ueda Y, Kanazawa T, Misawa Y, Jang I, Brenner JC, Ogawa T, Takebayashi S, Grenman RA, Herman JG, et al. (2008). Epigenetic inactivation of galanin receptor 1 in head and neck cancer. Clin Cancer Res 14, 7604-7613.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 7604-7613
-
-
Misawa, K.1
Ueda, Y.2
Kanazawa, T.3
Misawa, Y.4
Jang, I.5
Brenner, J.C.6
Ogawa, T.7
Takebayashi, S.8
Grenman, R.A.9
Herman, J.G.10
-
16
-
-
77949400528
-
Genotyping of 73 UM-SCC head and neck squamous cell carcinoma cell lines
-
Brenner JC, Graham MP, Kumar B, Saunders LM, Kupfer R, Lyons RH, Bradford CR, and Carey TE (2010). Genotyping of 73 UM-SCC head and neck squamous cell carcinoma cell lines. Head Neck 32, 417-426.
-
(2010)
Head Neck
, vol.32
, pp. 417-426
-
-
Brenner, J.C.1
Graham, M.P.2
Kumar, B.3
Saunders, L.M.4
Kupfer, R.5
Lyons, R.H.6
Bradford, C.R.7
Carey, T.E.8
-
17
-
-
0025734560
-
Immortalization of normal human oral keratinocytes with type 16 human papillomavirus
-
Park NH, Min BM, Li SL, Huang MZ, Cherick HM, and Doniger J (1991). Immortalization of normal human oral keratinocytes with type 16 human papillomavirus. Carcinogenesis 12, 1627-1631.
-
(1991)
Carcinogenesis
, vol.12
, pp. 1627-1631
-
-
Park, N.H.1
Min, B.M.2
Li, S.L.3
Huang, M.Z.4
Cherick, H.M.5
Doniger, J.6
-
18
-
-
0029843950
-
Methylation-specific PCR: A novel PCR assay for methylation status of CpG islands
-
Herman JG, Graff JR, Myohanen S, Nelkin BD, and Baylin SB (1996). Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands. Proc Natl Acad Sci USA 93, 9821-9826.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 9821-9826
-
-
Herman, J.G.1
Graff, J.R.2
Myohanen, S.3
Nelkin, B.D.4
Baylin, S.B.5
-
19
-
-
0038756374
-
Allele loss and promoter hypermethylation of VHL, RAR-β, RASSF1A, and FHIT tumor suppressor genes on chromosome 3p in esophageal squamous cell carcinoma
-
Kuroki T, Trapasso F, Yendamuri S, Matsuyama A, Alder H, Mori M, and Croce CM (2003). Allele loss and promoter hypermethylation of VHL, RAR-β, RASSF1A, and FHIT tumor suppressor genes on chromosome 3p in esophageal squamous cell carcinoma. Cancer Res 63, 3724-3728.
-
(2003)
Cancer Res
, vol.63
, pp. 3724-3728
-
-
Kuroki, T.1
Trapasso, F.2
Yendamuri, S.3
Matsuyama, A.4
Alder, H.5
Mori, M.6
Croce, C.M.7
-
20
-
-
34548853713
-
Association between hypermethylated tumor and paired surgical margins in head and neck squamous cell carcinomas
-
Martone T, Gillio-Tos A, De Marco L, Fiano V, Maule M, Cavalot A, Garzaro M, Merletti F, and Cortesina G (2007). Association between hypermethylated tumor and paired surgical margins in head and neck squamous cell carcinomas. Clin Cancer Res 13, 5089-5094.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 5089-5094
-
-
Martone, T.1
Gillio-Tos, A.2
de Marco, L.3
Fiano, V.4
Maule, M.5
Cavalot, A.6
Garzaro, M.7
Merletti, F.8
Cortesina, G.9
-
21
-
-
42549142983
-
DCC promoter hypermethylation in esophageal squamous cell carcinoma
-
Park HL, Kim MS, Yamashita K, Westra W, Carvalho AL, Lee J, Jiang WW, Baek JH, Liu J, Osada M, et al. (2008). DCC promoter hypermethylation in esophageal squamous cell carcinoma. Int J Cancer 122, 2498-2502.
-
(2008)
Int J Cancer
, vol.122
, pp. 2498-2502
-
-
Park, H.L.1
Kim, M.S.2
Yamashita, K.3
Westra, W.4
Carvalho, A.L.5
Lee, J.6
Jiang, W.W.7
Baek, J.H.8
Liu, J.9
Osada, M.10
-
22
-
-
0037142615
-
Patterns of gene promoter methylation in squamous cell cancer of the head and neck
-
Hasegawa M, Nelson HH, Peters E, Ringstrom E, Posner M, and Kelsey KT (2002). Patterns of gene promoter methylation in squamous cell cancer of the head and neck. Oncogene 21, 4231-4236.
-
(2002)
Oncogene
, vol.21
, pp. 4231-4236
-
-
Hasegawa, M.1
Nelson, H.H.2
Peters, E.3
Ringstrom, E.4
Posner, M.5
Kelsey, K.T.6
-
24
-
-
2342504654
-
Expression of neuropeptide galanin and galanin receptors in human skin
-
Kofler B, Berger A, Santic R, Moritz K, Almer D, Tuechler C, Lang R, Emberger M, Klausegger A, Sperl W, et al. (2004). Expression of neuropeptide galanin and galanin receptors in human skin. J Invest Dermatol 122, 1050-1053.
-
(2004)
J Invest Dermatol
, vol.122
, pp. 1050-1053
-
-
Kofler, B.1
Berger, A.2
Santic, R.3
Moritz, K.4
Almer, D.5
Tuechler, C.6
Lang, R.7
Emberger, M.8
Klausegger, A.9
Sperl, W.10
-
25
-
-
0031034503
-
Evidence that loss of chromosome 18q is associated with tumor progression
-
Frank CJ, McClatchey KD, Devaney KO, and Carey TE (1997). Evidence that loss of chromosome 18q is associated with tumor progression. Cancer Res 57, 824-827.
-
(1997)
Cancer Res
, vol.57
, pp. 824-827
-
-
Frank, C.J.1
McClatchey, K.D.2
Devaney, K.O.3
Carey, T.E.4
-
26
-
-
0031966351
-
Loss of 18q predicts poor survival of patients with squamous cell carcinoma of the head and neck
-
Pearlstein RP, Benninger MS, Carey TE, Zarbo RJ, Torres FX, Rybicki BA, and Dyke DL (1998). Loss of 18q predicts poor survival of patients with squamous cell carcinoma of the head and neck. Genes Chromosomes Cancer 21, 333-339.
-
(1998)
Genes Chromosomes Cancer
, vol.21
, pp. 333-339
-
-
Pearlstein, R.P.1
Benninger, M.S.2
Carey, T.E.3
Zarbo, R.J.4
Torres, F.X.5
Rybicki, B.A.6
Dyke, D.L.7
-
27
-
-
0034235567
-
Identification of new minimally lost regions on 18q in head and neck squamous cell carcinoma
-
Takebayashi S, Ogawa T, Jung KY, Muallem A, Mineta H, Fisher SG, Grenman R, and Carey TE (2000). Identification of new minimally lost regions on 18q in head and neck squamous cell carcinoma. Cancer Res 60, 3397-3403.
-
(2000)
Cancer Res
, vol.60
, pp. 3397-3403
-
-
Takebayashi, S.1
Ogawa, T.2
Jung, K.Y.3
Muallem, A.4
Mineta, H.5
Fisher, S.G.6
Grenman, R.7
Carey, T.E.8
-
28
-
-
65249160571
-
Galanin receptor subtype 2 suppresses cell proliferation and induces apoptosis in p53 mutant head and neck cancer cells
-
Kanazawa T, Kommareddi PK, Iwashita T, Kumar B, Misawa K, Misawa Y, Jang I, Nair TS, Iino Y, and Carey TE (2009). Galanin receptor subtype 2 suppresses cell proliferation and induces apoptosis in p53 mutant head and neck cancer cells. Clin Cancer Res 15, 2222-2230.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 2222-2230
-
-
Kanazawa, T.1
Kommareddi, P.K.2
Iwashita, T.3
Kumar, B.4
Misawa, K.5
Misawa, Y.6
Jang, I.7
Nair, T.S.8
Iino, Y.9
Carey, T.E.10
-
29
-
-
77149177951
-
Galanin receptor subtypes 1 and 2 as therapeutic targets in head and neck squamous cell carcinoma
-
Kanazawa T, Misawa K, and Carey TE (2010). Galanin receptor subtypes 1 and 2 as therapeutic targets in head and neck squamous cell carcinoma. Expert Opin Ther Targets 14, 289-302.
-
(2010)
Expert Opin Ther Targets
, vol.14
, pp. 289-302
-
-
Kanazawa, T.1
Misawa, K.2
Carey, T.E.3
-
30
-
-
78650845707
-
G protein-coupled receptors: Novel targets for drug discovery in cancer
-
Lappano R and Maggiolini M (2011). G protein-coupled receptors: novel targets for drug discovery in cancer. Nat Rev Drug Discov 10, 47-60.
-
(2011)
Nat Rev Drug Discov
, vol.10
, pp. 47-60
-
-
Lappano, R.1
Maggiolini, M.2
-
31
-
-
84876288615
-
Frequent promoter hypermethylation of tachykinin-1 and tachykinin receptor type 1 is a potential biomarker for head and neck cancer
-
Misawa K, Kanazawa T, Misawa Y, Imai A, Uehara T, Mochizuki D, Endo S, Takahashi G, and Mineta H (2013). Frequent promoter hypermethylation of tachykinin-1 and tachykinin receptor type 1 is a potential biomarker for head and neck cancer. J Cancer Res Clin Oncol.
-
(2013)
J Cancer Res Clin Oncol.
-
-
Misawa, K.1
Kanazawa, T.2
Misawa, Y.3
Imai, A.4
Uehara, T.5
Mochizuki, D.6
Endo, S.7
Takahashi, G.8
Mineta, H.9
-
32
-
-
33748108547
-
A genome-wide search identifies epigenetic silencing of somatostatin, tachykinin-1, and 5 other genes in colon cancer
-
Mori Y, Cai K, Cheng Y, Wang S, Paun B, Hamilton JP, Jin Z, Sato F, Berki AT, Kan T, et al. (2006). A genome-wide search identifies epigenetic silencing of somatostatin, tachykinin-1, and 5 other genes in colon cancer. Gastroenterology 131, 797-808.
-
(2006)
Gastroenterology
, vol.131
, pp. 797-808
-
-
Mori, Y.1
Cai, K.2
Cheng, Y.3
Wang, S.4
Paun, B.5
Hamilton, J.P.6
Jin, Z.7
Sato, F.8
Berki, A.T.9
Kan, T.10
-
33
-
-
0842269862
-
Galanin receptor subtype GalR2 mediates apoptosis in SH-SY5Y neuroblastoma cells
-
Berger A, Lang R, Moritz K, Santic R, Hermann A, Sperl W, and Kofler B (2004). Galanin receptor subtype GalR2 mediates apoptosis in SH-SY5Y neuroblastoma cells. Endocrinology 145, 500-507.
-
(2004)
Endocrinology
, vol.145
, pp. 500-507
-
-
Berger, A.1
Lang, R.2
Moritz, K.3
Santic, R.4
Hermann, A.5
Sperl, W.6
Kofler, B.7
-
34
-
-
40649089094
-
Galanin decreases proliferation of PC12 cells and induces apoptosis via its subtype 2 receptor (GalR2)
-
Tofighi R, Joseph B, Xia S, Xu ZQ, Hamberger B, Hokfelt T, and Ceccatelli S (2008). Galanin decreases proliferation of PC12 cells and induces apoptosis via its subtype 2 receptor (GalR2). Proc Natl Acad Sci USA 105, 2717-2722.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 2717-2722
-
-
Tofighi, R.1
Joseph, B.2
Xia, S.3
Xu, Z.Q.4
Hamberger, B.5
Hokfelt, T.6
Ceccatelli, S.7
-
35
-
-
79952384705
-
Cancer epigenetics reaches mainstream oncology
-
Rodriguez-Paredes M and Esteller M (2011). Cancer epigenetics reaches mainstream oncology. Nat Med 17, 330-339.
-
(2011)
Nat Med
, vol.17
, pp. 330-339
-
-
Rodriguez-Paredes, M.1
Esteller, M.2
-
36
-
-
83355175582
-
Synthetic small molecules for epigenetic activation of pluripotency genes in mouse embryonic fibroblasts
-
Pandian GN, Shinohara K, Ohtsuki A, Nakano Y, Masafumi M, Bando T, Nagase H, Yamada Y, Watanabe A, Terada N, et al. (2011). Synthetic small molecules for epigenetic activation of pluripotency genes in mouse embryonic fibroblasts. Chembiochem 12, 2822-2828.
-
(2011)
Chembiochem
, vol.12
, pp. 2822-2828
-
-
Pandian, G.N.1
Shinohara, K.2
Ohtsuki, A.3
Nakano, Y.4
Masafumi, M.5
Bando, T.6
Nagase, H.7
Yamada, Y.8
Watanabe, A.9
Terada, N.10
-
37
-
-
70449095972
-
Synthesis and properties of PI polyamide-SAHA conjugate
-
Ohtsuki A, Kimura M, Minoshima M, Suzuki T, Ikeda M, Bando T, Nagase H, Shinohara K, and Sugiyama H (2009). Synthesis and properties of PI polyamide-SAHA conjugate. Tetrahedron Lett 50, 7288-7292.
-
(2009)
Tetrahedron Lett
, vol.50
, pp. 7288-7292
-
-
Ohtsuki, A.1
Kimura, M.2
Minoshima, M.3
Suzuki, T.4
Ikeda, M.5
Bando, T.6
Nagase, H.7
Shinohara, K.8
Sugiyama, H.9
-
38
-
-
40849124009
-
DNA methylation markers and early recurrence in stage I lung cancer
-
Brock MV, Hooker CM, Ota-Machida E, Han Y, Guo M, Ames S, Glockner S, Piantadosi S, Gabrielson E, Pridham G, et al. (2008). DNA methylation markers and early recurrence in stage I lung cancer. N Engl J Med 358, 1118-1128.
-
(2008)
N Engl J Med
, vol.358
, pp. 1118-1128
-
-
Brock, M.V.1
Hooker, C.M.2
Ota-Machida, E.3
Han, Y.4
Guo, M.5
Ames, S.6
Glockner, S.7
Piantadosi, S.8
Gabrielson, E.9
Pridham, G.10
|