Quinidine, a life-saving medication for brugada syndrome, is inaccessible in many countries

Journal of the American College of Cardiology

Volumn 61, Issue 23, 2013, Pages 2383-2387

  Viskin, Sami ^a   Wilde, Arthur A M ^b   Guevara Valdivia, Milton E ^c   Daoulah, Amin ^d   Krahn, Andrew D ^e   Zipes, Douglas P ^f   Halkin, Amir ^a   Shivkumar, Kalyanam ^g   Boyle, Noel G ^g   Adler, Arnon ^a   Belhassen, Bernard ^a   Schapachnik, Edgardo ^h   Asrar, Farhan ⁱ   Rosso, Raphael ^a  

^a TEL AVIV UNIVERSITY   (Israel)

^b ACADEMIC MEDICAL CENTER   (Netherlands)

^c HOSPITAL DE ESPECIALIDADES   (Mexico)

^d KING FAISAL SPECIALIST HOSPITAL AND RESEARCH CENTER   (Saudi Arabia)

^e UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^f INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g UNIVERSITY OF CALIFORNIA   (United States)

^h Asociación Carlos Chagas   (Argentina)

ⁱ MCMASTER UNIVERSITY   (Canada)

Author keywords

arrhythmic storm; Brugada syndrome; idiopathic ventricular fibrillation; implantable cardioverter defibrillator; quinidine; ventricular fibrillation

Indexed keywords

QUINIDINE;

ARTICLE; BRUGADA SYNDROME; CLINICAL ARTICLE; DRUG BIOAVAILABILITY; DRUG MARKETING; GEOGRAPHIC DISTRIBUTION; HEALTH CARE ACCESS; HEALTH CARE SYSTEM; HEALTH CARE UTILIZATION; HEALTH HAZARD; HUMAN; MEDICAL SOCIETY; MEDICAL SPECIALIST; PRIORITY JOURNAL; QUESTIONNAIRE;

ANTI-ARRHYTHMIA AGENTS; BRUGADA SYNDROME; CROSS-SECTIONAL STUDIES; DRUG UTILIZATION; FEMALE; HEALTH SERVICES ACCESSIBILITY; HUMANS; MALE; NEEDS ASSESSMENT; QUESTIONNAIRES; QUINIDINE; RISK ASSESSMENT; SURVIVAL ANALYSIS; VENTRICULAR FIBRILLATION; WORLD HEALTH;

EID: 84878679774     PISSN: 07351097     EISSN: 15583597     Source Type: Journal    
DOI: 10.1016/j.jacc.2013.02.077     Document Type: Article

References (38)

1. A. Attaran, and L. Gillespie-White Do patents for antiretroviral drugs constrain access to AIDS treatment in Africa? JAMA 286 2001 1886 1892 (Pubitemid 33010242)
2. A.D. Federman, A.S. Adams, D. Ross-Degnan, S.B. Soumerai, and J.Z. Ayanian Supplemental insurance and use of effective cardiovascular drugs among elderly medicare beneficiaries with coronary heart disease JAMA 286 2001 1732 1739 (Pubitemid 33010259)
3. S. Viskin, C. Antzelevitch, M.F. Marquez, and B. Belhassen Quinidine: A valuable medication joins the list of 'endangered species' Europace 9 2007 1105 1106 (Pubitemid 351773249)
4. A.A. Wilde, and P. Langendijk Antiarrhythmic drugs, patients, and the pharmaceutical industry: value for patients, physicians, pharmacists or shareholders? Neth Heart J 15 2007 127 128 (Pubitemid 47253678)
5. S. Viskin, B. Belhassen, and A.A. Wilde To the editor - Irreplaceable antiarrhythmic medications are disappearing: the case of quinidine Heart Rhythm 7 2010 863
6. B. Belhassen, A. Glick, and S. Viskin Efficacy of quinidine in high-risk patients with Brugada syndrome Circulation 110 2004 1731 1737 (Pubitemid 39299213)
7. B. Belhassen, S. Viskin, R. Fish, A. Glick, I. Setbon, and M. Eldar Effects of electrophysiologic-guided therapy with Class IA antiarrhythmic drugs on the long-term outcome of patients with idiopathic ventricular fibrillation with or without the Brugada syndrome J Cardiovasc Electrophysiol 10 1999 1301 1312 (Pubitemid 29468567)
8. J.S. Hermida, I. Denjoy, and J. Clerc Hydroquinidine therapy in Brugada syndrome J Am Coll Cardiol 43 2004 1853 1860 (Pubitemid 38622526)
9. K. Bettiol, L. Gianfranchi, S. Scarfo, F. Pacchioni, M. Pedaci, and P. Alboni Successful treatment of electrical storm with oral quinidine in Brugada syndrome Ital Heart J 6 2005 601 602
10. M. Haghjoo, A. Arya, A. Heidari, and M.A. Sadr-Ameli Suppression of electrical storm by oral quinidine in a patient with Brugada syndrome J Cardiovasc Electrophysiol 16 2005 674 (Pubitemid 40807662)
11. J.K. Jongman, N. Jepkes-Bruin, and A.R. Ramdat Misier Electrical storms in Brugada syndrome successfully treated with isoproterenol infusion and quinidine orally Neth Heart J 15 2007 151 155
12. M.F. Marquez, J. Rivera, and A.G. Hermosillo Arrhythmic storm responsive to quinidine in a patient with Brugada syndrome and vasovagal syncope Pacing Clin Electrophysiol 28 2005 870 873 (Pubitemid 41648232)
13. N.S. Mok, N.Y. Chan, and A.C. Chiu Successful use of quinidine in treatment of electrical storm in Brugada syndrome Pacing Clin Electrophysiol 27 2004 821 823 (Pubitemid 38758770)
14. T. Ohgo, H. Okamura, and T. Noda Acute and chronic management in patients with Brugada syndrome associated with electrical storm of ventricular fibrillation Heart Rhythm 4 2007 695 700 (Pubitemid 46840335)
15. B. Belhassen A 25-year control of idiopathic ventricular fibrillation with electrophysiologic-guided antiarrhythmic drug therapy Heart Rhythm 1 2004 352 354 (Pubitemid 39549768)
16. B. Belhassen, A. Glick, and S. Viskin Excellent long-term reproducibility of the electrophysiologic efficacy of quinidine in patients with idiopathic ventricular fibrillation and Brugada syndrome Pacing Clin Electrophysiol 32 2009 294 301
17. B. Belhassen, A. Pelleg, H.I. Miller, and S. Laniado Serial electrophysiological studies in a young patient with recurrent ventricular fibrillation Pacing Clin Electrophysiol 4 1981 92 99 (Pubitemid 11174559)
18. B. Belhassen, I. Shapira, D. Shoshani, A. Paredes, H. Miller, and S. Laniado Idiopathic ventricular fibrillation: inducibility and beneficial effects of class I antiarrhythmic agents Circulation 75 1987 809 816 (Pubitemid 17052666)
19. B. Belhassen, and S. Viskin Idiopathic ventricular tachycardia and fibrillation J Cardiovasc Electrophysiol 4 1993 356 368 (Pubitemid 23164677)
20. S. Viskin, and B. Belhassen Idiopathic ventricular fibrillation Am Heart J 120 1990 661 671 (Pubitemid 20312599)
21. M. Haissaguerre, N. Derval, and F. Sacher Sudden cardiac arrest associated with early repolarization N Engl J Med 358 2008 2016 2023 (Pubitemid 351681636)
22. M. Haissaguerre, F. Sacher, and A. Nogami Characteristics of recurrent ventricular fibrillation associated with inferolateral early repolarization role of drug therapy J Am Coll Cardiol 53 2009 612 619
23. S. Viskin Idiopathic ventricular fibrillation "Le Syndrome d'Haissaguerre" and the fear of J waves J Am Coll Cardiol 53 2009 620 622
24. E.S. Kaufman Quinidine in short QT syndrome: An old drug for a new disease J Cardiovasc Electrophysiol 18 2007 665 666 (Pubitemid 46800514)
25. C. Wolpert, R. Schimpf, and C. Giustetto Further insights into the effect of quinidine in short QT syndrome caused by a mutation in HERG J Cardiovasc Electrophysiol 16 2005 54 58 (Pubitemid 40165452)
26. G. Olsson To the editor - Market withdrawal of quinidine bisulfate (Kinidin Durules) in 2006 Heart Rhythm 7 2010 864
27. M.F. Marquez, G. Salica, and A.G. Hermosillo Ionic basis of pharmacological therapy in Brugada syndrome J Cardiovasc Electrophysiol 18 2007 234 240 (Pubitemid 46131388)
28. S. Viskin, A.A. Wilde, H.L. Tan, C. Antzelevitch, W. Shimizu, and B. Belhassen Empiric quinidine therapy for asymptomatic Brugada syndrome: time for a prospective registry Heart Rhythm 6 2009 401 404
29. M.A. Brodsky, J.G. Chun, P.J. Podrid, S. Douban, B.J. Allen, and R. Cygan Regional attitudes of generalists, specialists, and subspecialists about management of atrial fibrillation Arch Intern Med 156 1996 2553 2562 (Pubitemid 26404792)
30. A.A. Grace, and A.J. Camm Quinidine N Engl J Med 338 1998 35 45 (Pubitemid 28040538)
31. J.L. Bauman, R.A. Bauernfeind, J.V. Hoff, B. Strasberg, S. Swiryn, and K.M. Rosen Torsade de pointes due to quinidine: observations in 31 patients Am Heart J 107 1984 425 430 (Pubitemid 14167715)
32. N. El-Sherif, S.S. Bekheit, and R. Henkin Quinidine-induced long QTU interval and torsade de pointes: role of bradycardia-dependent early afterdepolarizations J Am Coll Cardiol 14 1989 252 257 (Pubitemid 19165560)
33. D. Roden, R. Woosley, and R. Primm Incidence and clinical features of the quinidine-associated long QT syndrome: Implications for patient care Am Heart J 111 1986 1088 1093 (Pubitemid 16085013)
34. Preliminary report: effect of encainide and flecainide on mortality in a randomized trial of arrhythmia suppression after myocardial infarction. The Cardiac Arrhythmia Suppression Trial (CAST) Investigators N Engl J Med 321 1989 406 412
35. S.E. Coplen, E.M. Antman, J.A. Berlin, P. Hewitt, and T.C. Chalmers Efficacy and safety of quinidine therapy for maintenance of sinus rhythm after cardioversion. A meta-analysis of randomized control trials Circulation 82 1990 1106 1116
36. C. Antzelevitch The Brugada syndrome: ionic basis and arrhythmia mechanisms J Cardiovasc Electrophysiol 12 2001 268 272 (Pubitemid 32171521)
37. M. Vatta, R. Dumaine, and G. Varghese Genetic and biophysical basis of sudden unexplained nocturnal death syndrome (SUNDS), a disease allelic to Brugada syndrome Hum Mol Genet 11 2002 337 345 (Pubitemid 34173363)
38. S. Mehrotra, R. Juneja, N. Naik, and B.B. Pavri Successful use of quinine in the treatment of electrical storm in a child with Brugada syndrome J Cardiovasc Electrophysiol 22 2011 594 597