Cisplatin-induced ototoxicity in pediatric solid tumors: The role of glutathione S-transferases and megalin genetic polymorphisms

Journal of Pediatric Hematology/Oncology

Volumn 35, Issue 4, 2013, Pages

  Choeyprasert, Worawut ^a   Sawangpanich, Rachchadol ^b   Lertsukprasert, Krisna ^b   Udomsubpayakul, Umaporn ^b   Songdej, Duantida ^b   Unurathapan, Usanarat ^b   Pakakasama, Samart ^b   Hongeng, Suradej ^b  

^a Faculty of Medicine Chiang Mai University   (Thailand)

^b MAHIDOL UNIVERSITY   (Thailand)

Author keywords

Cisplatin; Genetic polymorphisms; Glutathione S transferase; GST; Megalin; Ototoxicity

Indexed keywords

CISPLATIN; GLUTATHIONE TRANSFERASE; MEGALIN; ANTINEOPLASTIC AGENT; GLUTATHIONE S-TRANSFERASE M1; GLUTATHIONE S-TRANSFERASE T1; GLUTATHIONE TRANSFERASE M1; GLUTATHIONE TRANSFERASE T1;

ADOLESCENT; ARTICLE; AUDIOMETRY; CANCER CHEMOTHERAPY; CHILD; CHILDHOOD CANCER; DISEASE ASSOCIATION; DRUG INDUCED DISEASE; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC RISK; GENETIC VARIABILITY; GENOTYPE; GSTM1 GENE; GSTT1 GENE; HEARING IMPAIRMENT; HUMAN; MAJOR CLINICAL STUDY; MALE; MEGALIN GENE; OTOTOXICITY; PRESCHOOL CHILD; PRIORITY JOURNAL; RISK ASSESSMENT; SCHOOL CHILD; SINGLE NUCLEOTIDE POLYMORPHISM; SOLID TUMOR; CHEMICALLY INDUCED DISORDER; GENETICS; INFANT; NEOPLASM;

ADOLESCENT; ANTINEOPLASTIC AGENTS; CHILD; CHILD, PRESCHOOL; CISPLATIN; FEMALE; GLUTATHIONE TRANSFERASE; HEARING LOSS; HUMANS; INFANT; LOW DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN-2; MALE; NEOPLASMS; POLYMORPHISM, SINGLE NUCLEOTIDE;

MLCS; MLOWN;

EID: 84878653311     PISSN: 10774114     EISSN: 15363678     Source Type: Journal    
DOI: 10.1097/MPH.0b013e3182707fc5     Document Type: Article

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