-
1
-
-
0034788240
-
The occurrence and signi ficance of v gene mutations in b cell-derived human malignancy
-
Stevenson FK, Sahota SS, Ottensmeier CH, Zhu D, Forconi F, Hamblin TJ (2001) The occurrence and signi ficance of V gene mutations in B cell-derived human malignancy. Adv Cancer Res 83:81-116
-
(2001)
Adv Cancer Res
, vol.83
, pp. 81-116
-
-
Stevenson, F.K.1
Sahota, S.S.2
Ottensmeier, C.H.3
Zhu, D.4
Forconi, F.5
Hamblin, T.J.6
-
2
-
-
0042971643
-
B cell chronic lymphocytic leukemia: Lessons learned from studies of the b cell antigen receptor
-
Chiorazzi N, Ferrarini M (2003) B cell chronic lymphocytic leukemia: lessons learned from studies of the B cell antigen receptor. Annu Rev Immunol 21:841-894
-
(2003)
Annu Rev Immunol
, vol.21
, pp. 841-894
-
-
Chiorazzi, N.1
Ferrarini, M.2
-
5
-
-
84861345119
-
The bruton's tyrosine kinase (btk) inhibitor pci-32765 induces durable responses in relapsed or refractory (r/r) chronic lymphocytic leukemia/small lymphocytic lymphoma (cll/sll): Follow-up of a phase ib/ii study
-
(Abstract 983)
-
O'Brien S, Burger J, Blum KA et al (2011) The Bruton's Tyrosine Kinase (BTK) inhibitor PCI-32765 induces durable responses in relapsed or refractory (R/R) chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL): follow-up of a phase Ib/II study. Blood 118 (Abstract 983)
-
(2011)
Blood
, vol.118
-
-
O'Brien, S.1
Burger, J.2
Blum, K.A.3
-
6
-
-
84860430028
-
The bruton's tyrosine kinase inhibitor pci-32765 is highly active as single-agent therapy in previously-treated mantle cell lymphoma (mcl): Preliminary results of a phase ii trial
-
(Abstract 442)
-
Wang L, Martin P, Blum KA et al (2011) The Bruton's Tyrosine Kinase inhibitor PCI-32765 is highly active as single-agent therapy in previously-treated mantle cell lymphoma (MCL): preliminary results of a phase II trial. Blood 118 (Abstract 442)
-
(2011)
Blood
, vol.118
-
-
Wang, L.1
Martin, P.2
Blum, K.A.3
-
7
-
-
79951498701
-
Cellular origin(s) of chronic lymphocytic leukemia: Cautionary notes and additional considerations and possibilities
-
Chiorazzi N, Ferrarini M (2011) Cellular origin(s) of chronic lymphocytic leukemia: cautionary notes and additional considerations and possibilities. Blood 117:1781-1791
-
(2011)
Blood
, vol.117
, pp. 1781-1791
-
-
Chiorazzi, N.1
Ferrarini, M.2
-
8
-
-
0028355650
-
The pathogenesis of chronic lymphocytic leukemia: Analysis of the antibody repertoire
-
Schroeder HW Jr, Dighiero G (1994) The pathogenesis of chronic lymphocytic leukemia: analysis of the antibody repertoire. Immunol Today 15:288-294
-
(1994)
Immunol Today
, vol.15
, pp. 288-294
-
-
Schroeder Jr., H.W.1
Dighiero, G.2
-
9
-
-
0032532668
-
Chronic lymphocytic leukemia b cells express restricted sets of mutated and unmutated antigen receptors
-
Fais F, Ghiotto F, Hashimoto S et al (1998) Chronic lymphocytic leukemia B cells express restricted sets of mutated and unmutated antigen receptors. J Clin Invest 102:1515-1525
-
(1998)
J Clin Invest
, vol.102
, pp. 1515-1525
-
-
Fais, F.1
Ghiotto, F.2
Hashimoto, S.3
-
10
-
-
27744598787
-
Immunoglobulin light chain repertoire in chronic lymphocytic leukemia
-
Stamatopoulos K, Belessi C, Hadzidimitriou A et al (2005) Immunoglobulin light chain repertoire in chronic lymphocytic leukemia. Blood 106:3575-3583
-
(2005)
Blood
, vol.106
, pp. 3575-3583
-
-
Stamatopoulos, K.1
Belessi, C.2
Hadzidimitriou, A.3
-
11
-
-
0033567968
-
Ig v gene mutation status and cd38 expression as novel prognostic indicators in chronic lymphocytic leukemia
-
Damle RN, Wasil T, Fais F et al (1999) Ig V gene mutation status and CD38 expression as novel prognostic indicators in chronic lymphocytic leukemia. Blood 94:1840-1847
-
(1999)
Blood
, vol.94
, pp. 1840-1847
-
-
Damle, R.N.1
Wasil, T.2
Fais, F.3
-
12
-
-
0033567907
-
Unmutated ig v(h) genes are associated with a more aggressive form of chronic lymphocytic leukemia
-
Hamblin TJ, Davis Z, Gardiner A, Oscier DG, Stevenson FK (1999) Unmutated Ig V(H) genes are associated with a more aggressive form of chronic lymphocytic leukemia. Blood 94:1848-1854
-
(1999)
Blood
, vol.94
, pp. 1848-1854
-
-
Hamblin, T.J.1
Davis, Z.2
Gardiner, A.3
Oscier, D.G.4
Stevenson, F.K.5
-
13
-
-
33845513520
-
European research initiative on cll. Eric recommendations on ighv gene mutational status analysis in chronic lymphocytic leukemia
-
Ghia P, Stamatopoulos K, Belessi C et al (2007) European Research Initiative on CLL. ERIC recommendations on IGHV gene mutational status analysis in chronic lymphocytic leukemia. Leukemia 21:1-3
-
(2007)
Leukemia
, vol.21
, pp. 1-3
-
-
Ghia, P.1
Stamatopoulos, K.2
Belessi, C.3
-
14
-
-
79958131059
-
European research initiative on cll (eric). Immunoglobulin sequence analysis and prognostication in cll: Guidelines from the eric review board for reliable interpretation of problematic cases
-
Langerak AW, Davi F, Ghia P et al (2011) European Research Initiative on CLL (ERIC). Immunoglobulin sequence analysis and prognostication in CLL: guidelines from the ERIC review board for reliable interpretation of problematic cases. Leukemia 25:979-984
-
(2011)
Leukemia
, vol.25
, pp. 979-984
-
-
Langerak, A.W.1
Davi, F.2
Ghia, P.3
-
15
-
-
0028945621
-
Somatic diversi fication and selection of immunoglobulin heavy and light chain variable region genes in igg+ cd5+ chronic lymphocytic leukemia b cells
-
Hashimoto S, Dono M, Wakai M et al (1995) Somatic diversi fication and selection of immunoglobulin heavy and light chain variable region genes in IgG+ CD5+ chronic lymphocytic leukemia B cells. J Exp Med 181:1507-1517
-
(1995)
J Exp Med
, vol.181
, pp. 1507-1517
-
-
Hashimoto, S.1
Dono, M.2
Wakai, M.3
-
16
-
-
0029665035
-
Restricted immunoglobulin vh region repertoire in chronic lymphocytic leukemia patients with autoimmune hemolytic anemia
-
Efremov DG, Ivanovski M, Siljanovski N et al (1996) Restricted immunoglobulin VH region repertoire in chronic lymphocytic leukemia patients with autoimmune hemolytic anemia. Blood 87:3869-3876
-
(1996)
Blood
, vol.87
, pp. 3869-3876
-
-
Efremov, D.G.1
Ivanovski, M.2
Siljanovski, N.3
-
17
-
-
0030639650
-
Ig vh1 genes expressed in b cell chronic lymphocytic leukemia exhibit distinctive molecular features
-
Johnson TA, Rassenti LZ, Kipps TJ (1997) Ig VH1 genes expressed in B cell chronic lymphocytic leukemia exhibit distinctive molecular features. J Immunol 158:235-246
-
(1997)
J Immunol
, vol.158
, pp. 235-246
-
-
Johnson, T.A.1
Rassenti, L.Z.2
Kipps, T.J.3
-
18
-
-
0035164178
-
Normal b cells express 51p1-encoded ig heavy chains that are distinct from those expressed by chronic lymphocytic leukemia b cells
-
Widhopf GF 2nd, Kipps TJ (2001) Normal B cells express 51p1-encoded Ig heavy chains that are distinct from those expressed by chronic lymphocytic leukemia B cells. J Immunol 166:95-102
-
(2001)
J Immunol
, vol.166
, pp. 95-102
-
-
Widhopf, G.F.1
Kipps, T.J.2
-
19
-
-
10744230550
-
Chronic lymphocytic leukemias utilizing the vh3-21 gene display highly restricted vlambda2-14 gene use and homologous cdr3s: Implicating recognition of a common antigen epitope
-
Tobin G, Thunberg U, Johnson A et al (2003) Chronic lymphocytic leukemias utilizing the VH3-21 gene display highly restricted Vlambda2-14 gene use and homologous CDR3s: implicating recognition of a common antigen epitope. Blood 101:4952-4957
-
(2003)
Blood
, vol.101
, pp. 4952-4957
-
-
Tobin, G.1
Thunberg, U.2
Johnson, A.3
-
20
-
-
4944244255
-
Chronic lymphocytic leukemia b cells of more than 1% of patients express virtually identical immunoglobulins
-
Widhopf GF 2nd, Rassenti LZ, Toy TL, Gribben JG, Wierda WG, Kipps TJ (2004) Chronic lymphocytic leukemia B cells of more than 1% of patients express virtually identical immunoglobulins. Blood 104:2499-2504
-
(2004)
Blood
, vol.104
, pp. 2499-2504
-
-
Widhopf, G.F.1
Rassenti, L.Z.2
Toy, T.L.3
Gribben, J.G.4
Wierda, W.G.5
Kipps, T.J.6
-
21
-
-
11144356992
-
Remarkably similar antigen receptors among a subset of patients with chronic lymphocytic leukemia
-
Ghiotto F, Fais F, Valetto A et al (2004) Remarkably similar antigen receptors among a subset of patients with chronic lymphocytic leukemia. J Clin Invest 113:1008-1016
-
(2004)
J Clin Invest
, vol.113
, pp. 1008-1016
-
-
Ghiotto, F.1
Fais, F.2
Valetto, A.3
-
22
-
-
4344704897
-
Multiple distinct sets of stereotyped antigen receptors indicate a role for antigen in promoting chronic lymphocytic leukemia
-
Messmer BT, Albesiano E, Efremov DG et al (2004) Multiple distinct sets of stereotyped antigen receptors indicate a role for antigen in promoting chronic lymphocytic leukemia. J Exp Med 200:519-525
-
(2004)
J Exp Med
, vol.200
, pp. 519-525
-
-
Messmer, B.T.1
Albesiano, E.2
Efremov, D.G.3
-
23
-
-
7244232709
-
Subsets with restricted immunoglobulin gene rearrangement features indicate a role for antigen selection in the development of chronic lymphocytic leukemia
-
Tobin G, Thunberg U, Karlsson K et al (2004) Subsets with restricted immunoglobulin gene rearrangement features indicate a role for antigen selection in the development of chronic lymphocytic leukemia. Blood 104:2879-2885
-
(2004)
Blood
, vol.104
, pp. 2879-2885
-
-
Tobin, G.1
Thunberg, U.2
Karlsson, K.3
-
24
-
-
33846108722
-
Over 20% of patients with chronic lymphocytic leukemia carry stereotyped receptors: Pathogenetic implications and clinical correlations
-
Stamatopoulos K, Belessi C, Moreno C et al (2007) Over 20% of patients with chronic lymphocytic leukemia carry stereotyped receptors: pathogenetic implications and clinical correlations. Blood 109:259-270
-
(2007)
Blood
, vol.109
, pp. 259-270
-
-
Stamatopoulos, K.1
Belessi, C.2
Moreno, C.3
-
25
-
-
38949203770
-
Stereotyped patterns of somatic hypermutation in subsets of patients with chronic lymphocytic leukemia: Implications for the role of antigen selection in leukemogenesis
-
Murray F, Darzentas N, Hadzidimitriou A et al (2008) Stereotyped patterns of somatic hypermutation in subsets of patients with chronic lymphocytic leukemia: implications for the role of antigen selection in leukemogenesis. Blood 111:1524-1533
-
(2008)
Blood
, vol.111
, pp. 1524-1533
-
-
Murray, F.1
Darzentas, N.2
Hadzidimitriou, A.3
-
26
-
-
58549100059
-
Molecular and clinical features of chronic lymphocytic leukaemia with stereotyped b cell receptors: Results from an italian multicentre study
-
Bomben R, Dal Bo M, Capello D et al (2009) Molecular and clinical features of chronic lymphocytic leukaemia with stereotyped B cell receptors: results from an Italian multicentre study. Br J Haematol 144:492-506
-
(2009)
Br J Haematol
, vol.144
, pp. 492-506
-
-
Bomben, R.1
Dal Bo, M.2
Capello, D.3
-
27
-
-
74249107417
-
A different ontogenesis for chronic lymphocytic leukemia cases carrying stereotyped antigen receptors: Molecular and computational evidence
-
Darzentas N, Hadzidimitriou A, Murray F et al (2010) A different ontogenesis for chronic lymphocytic leukemia cases carrying stereotyped antigen receptors: molecular and computational evidence. Leukemia 24:125-132
-
(2010)
Leukemia
, vol.24
, pp. 125-132
-
-
Darzentas, N.1
Hadzidimitriou, A.2
Murray, F.3
-
28
-
-
80052929598
-
Is there a role for antigen selection in mantle cell lymphoma? Immunogenetic support from a series of 807 cases
-
Hadzidimitriou A, Agathangelidis A, Darzentas N et al (2011) Is there a role for antigen selection in mantle cell lymphoma? Immunogenetic support from a series of 807 cases. Blood 118:3088-3095
-
(2011)
Blood
, vol.118
, pp. 3088-3095
-
-
Hadzidimitriou, A.1
Agathangelidis, A.2
Darzentas, N.3
-
29
-
-
82555169707
-
Unlocking the secrets of immunoglobulin receptors in mantle cell lymphoma: Implications for the origin and selection of the malignant cells
-
Agathangelidis A, Hadzidimitriou A, Rosenquist R, Stamatopoulos K (2011) Unlocking the secrets of immunoglobulin receptors in mantle cell lymphoma: implications for the origin and selection of the malignant cells. Semin Cancer Biol 21:299-307
-
(2011)
Semin Cancer Biol
, vol.21
, pp. 299-307
-
-
Agathangelidis, A.1
Hadzidimitriou, A.2
Rosenquist, R.3
Stamatopoulos, K.4
-
30
-
-
84863785935
-
Over 30% of patients with splenic marginal zone lymphoma express the same immunoglobulin heavy variable gene: Ontogenetic implications
-
Bikos V, Darzentas N, Hadzidimitriou A et al (2012) Over 30% of patients with splenic marginal zone lymphoma express the same immunoglobulin heavy variable gene: ontogenetic implications. Leukemia. 26:1638-1646]
-
(2012)
Leukemia.
, vol.26
, pp. 1638-1646
-
-
Bikos, V.1
Darzentas, N.2
Hadzidimitriou, A.3
-
31
-
-
77957776534
-
Stereotyped patterns of b-cell receptor in splenic marginal zone lymphoma
-
Zibellini S, Capello D, Forconi F et al (2010) Stereotyped patterns of B-cell receptor in splenic marginal zone lymphoma. Haematologica 95:1792-1796
-
(2010)
Haematologica
, vol.95
, pp. 1792-1796
-
-
Zibellini, S.1
Capello, D.2
Forconi, F.3
-
32
-
-
0033711628
-
Diversity in the cdr3 region of v(h) is suf ficient for most antibody speci ficities
-
Xu JL, Davis MM (2000) Diversity in the CDR3 region of V(H) is suf ficient for most antibody speci ficities. Immunity 13:37-45
-
(2000)
Immunity
, vol.13
, pp. 37-45
-
-
Xu, J.L.1
Davis, M.M.2
-
33
-
-
3142613577
-
Length of the antibody heavy chain complementarity determining region 3 as a speci ficity-determining factor
-
Barrios Y, Jirholt P, Ohlin M (2004) Length of the antibody heavy chain complementarity determining region 3 as a speci ficity-determining factor. J Mol Recognit 17:332-338
-
(2004)
J Mol Recognit
, vol.17
, pp. 332-338
-
-
Barrios, Y.1
Jirholt, P.2
Ohlin, M.3
-
34
-
-
0027317580
-
Performance evaluation of amino acid substitution matrices
-
Henikoff S, Henikoff JG (1993) Performance evaluation of amino acid substitution matrices. Proteins 17:49-61
-
(1993)
Proteins
, vol.17
, pp. 49-61
-
-
Henikoff, S.1
Henikoff, J.G.2
-
35
-
-
80355126549
-
Toll-like receptor signaling pathway in chronic lymphocytic leukemia: Distinct gene expression pro files of potential pathogenetic signi ficance in speci fic subsets of patients
-
Arvaniti E, Ntoufa S, Papakonstantinou N et al (2011) Toll-like receptor signaling pathway in chronic lymphocytic leukemia: distinct gene expression pro files of potential pathogenetic signi ficance in speci fic subsets of patients. Haematologica 96:1644-1652
-
(2011)
Haematologica
, vol.96
, pp. 1644-1652
-
-
Arvaniti, E.1
Ntoufa, S.2
Papakonstantinou, N.3
-
36
-
-
0026592314
-
Immunoglobulin vh clan and family identity predicts variable domain structure and may in fl uence antigen binding
-
Kirkham PM, Mortari F, Newton JA, Schroeder HW Jr (1992) Immunoglobulin VH clan and family identity predicts variable domain structure and may in fl uence antigen binding. EMBO J 11:603-609
-
(1992)
EMBO J
, vol.11
, pp. 603-609
-
-
Kirkham, P.M.1
Mortari, F.2
Newton, J.A.3
Schroeder Jr., H.W.4
-
37
-
-
0031684427
-
Combinatorial pattern discovery in biological sequences: The teiresias algorithm
-
Rigoutsos I, Floratos A (1998) Combinatorial pattern discovery in biological sequences: the TEIRESIAS algorithm. Bioinformatics 14: 55-67
-
(1998)
Bioinformatics
, vol.14
, pp. 55-67
-
-
Rigoutsos, I.1
Floratos, A.2
-
38
-
-
1242276733
-
Imgt standardized criteria for statistical analysis of immunoglobulin v-region amino acid properties
-
Pommie C, Levadoux S, Sabatier R, Lefranc G, Lefranc MP (2004) IMGT standardized criteria for statistical analysis of immunoglobulin V-REGION amino acid properties. J Mol Recognit 17:17-32
-
(2004)
J Mol Recognit
, vol.17
, pp. 17-32
-
-
Pommie, C.1
Levadoux, S.2
Sabatier, R.3
Lefranc, G.4
Lefranc, M.P.5
-
39
-
-
84861033763
-
Stereotyped b-cell receptors in one-third of chronic lymphocytic leukemia: A molecular classi fication with implications for targeted therapies
-
Agathangelidis A, Darzentas N, Hadzidimitriou A et al (2012) Stereotyped B-cell receptors in one-third of chronic lymphocytic leukemia: a molecular classi fication with implications for targeted therapies. Blood 119:4467-4475
-
(2012)
Blood
, vol.119
, pp. 4467-4475
-
-
Agathangelidis, A.1
Darzentas, N.2
Hadzidimitriou, A.3
|