Conditionally immortalized stem cell lines from human spinal cord retain regional identity and generate functional V2a interneurons and motorneurons

Stem Cell Research and Therapy

Volumn 4, Issue 3, 2013, Pages

  Cocks, Graham ^a   Romanyuk, Nataliya ^b   Amemori, Takashi ^b   Jendelova, Pavla ^b,c   Forostyak, Oksana ^b   Jeffries, Aaron R ^a   Perfect, Leo ^a   Thuret, Sandrine ^a   Dayanithi, Govindan ^b,d   Sykova, Eva ^b,c   Price, Jack ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b INSTITUTE OF EXPERIMENTAL MEDICINE   (Czech Republic)

^c CHARLES UNIVERSITY   (Czech Republic)

^d INSERM   (France)

Author keywords

Motoneurons; Neural stem cells; Spinal cord; Spontaneous Ca2+ oscillations; V2a interneurons; Voltage operated Ca2+ channels

Indexed keywords

CALCIUM CHANNEL; ENHANCED GREEN FLUORESCENT PROTEIN; CALCIUM; DIPEPTIDE; N-(N-(3,5-DIFLUOROPHENACETYL)ALANYL)PHENYLGLYCINE TERT-BUTYL ESTER; NOTCH RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CALCIUM TRANSPORT; CARCINOGENESIS; CELL CLONE; CELL DIFFERENTIATION; CELL FATE; CELL FUNCTION; CELL IMMORTALIZATION; CELL SURVIVAL; CELL TRANSPLANTATION; CONTROLLED STUDY; FEMALE; FETUS; FETUS CELL; GENE EXPRESSION PROFILING; HUMAN; HUMAN CELL; IN VITRO STUDY; INTERNEURON; KARYOTYPE; MALE; MICROARRAY ANALYSIS; MOTONEURON; NEURAL STEM CELL; NONHUMAN; ONCOGENE C MYC; PRIORITY JOURNAL; RAT; SPINAL CORD; SPINAL CORD NERVE CELL; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL CULTURE; CYTOLOGY; DRUG EFFECTS; KARYOTYPING; METABOLISM; SPINAL CORD INJURIES; TRANSPLANTATION; WISTAR RAT; XENOGRAFT;

RATTUS;

ANIMALS; CALCIUM; CELL DIFFERENTIATION; CELLS, CULTURED; DIPEPTIDES; FETUS; HUMANS; INTERNEURONS; KARYOTYPING; MALE; MOTOR NEURONS; NEURAL STEM CELLS; RATS; RATS, WISTAR; RECEPTORS, NOTCH; SPINAL CORD; SPINAL CORD INJURIES; TRANSPLANTATION, HETEROLOGOUS;

EID: 84878646860     PISSN: None     EISSN: 17576512     Source Type: Journal    
DOI: 10.1186/scrt220     Document Type: Article

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