Quantification of myocardial perfusion reserve using dynamic SPECT imaging in humans: A feasibility study

Journal of Nuclear Medicine

Volumn 54, Issue 6, 2013, Pages 873-879

  Ben Haim, Simona ^a,b,c   Murthy, Venkatesh L ^d,e   Breault, Christopher ^e   Allie, Rayjanah ^a   Sitek, Arkadiusz ^e   Roth, Nathaniel ^f   Fantony, Jolene ^e   Moore, Stephen C ^e   Park, Mi Ae ^e   Kijewski, Marie ^e   Haroon, Athar ^a   Slomka, Piotr ^g   Erlandsson, Kjell ^b   Baavour, Rafael ^f   Zilberstien, Yoel ^f   Bomanji, Jamshed ^a,b,c   Di Carli, Marcelo F ^e  

^a UNIVERSITY COLLEGE LONDON HOSPITALS   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c SHEBA MEDICAL CENTER   (Israel)

^d UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^e BRIGHAM AND WOMEN S HOSPITAL   (United States)

^f Spectrum Dynamics   (Israel)

^g CEDARS SINAI MEDICAL CENTER   (United States)

Author keywords

Coronary artery disease; Dynamic SPECT; Myocardial perfusion imaging; Quantification; Solid state camera

Indexed keywords

TECHNETIUM 99M; TRACER;

ADULT; AGED; ANGIOCARDIOGRAPHY; ARTICLE; CINEANGIOCARDIOGRAPHY; COHORT ANALYSIS; CONTROLLED STUDY; CORONARY ARTERY DISEASE; DIAGNOSTIC IMAGING; FACTORIAL ANALYSIS; FEASIBILITY STUDY; FEMALE; HEART MUSCLE PERFUSION; HUMAN; IMAGE ANALYSIS; KINETICS; LIMIT OF QUANTITATION; MAJOR CLINICAL STUDY; MALE; MYOCARDIAL PERFUSION IMAGING; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; REPRODUCIBILITY; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; SOLID STATE;

CORONARY ARTERY DISEASE; DYNAMIC SPECT; MYOCARDIAL PERFUSION IMAGING; QUANTIFICATION; SOLID-STATE CAMERA;

AGED; CADMIUM; COHORT STUDIES; CORONARY ARTERY DISEASE; FEASIBILITY STUDIES; FEMALE; HUMANS; MALE; MIDDLE AGED; MYOCARDIAL PERFUSION IMAGING; SENSITIVITY AND SPECIFICITY; TELLURIUM; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON; ZINC;

EID: 84878637226     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: 10.2967/jnumed.112.109652     Document Type: Article

References (36)

1. Gibbons RJ, Chatterjee K, Daley J, et al. ACC/AHA/ACP-ASIM guidelines for the management of patients with chronic stable angina: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Management of Patients with Chronic Stable Angina). J Am Coll Cardiol. 1999;33:2092-2197.
2. Shaw LJ, Iskandrian AE. Prognostic value of gated myocardial perfusion SPECT. J Nucl Cardiol. 2004;11:171-185. (Pubitemid 38949912)
3. Hachamovitch R, Hayes S, Friedman JD, et al. Determinants of risk and its temporal variation in patients with normal stress myocardial perfusion scans: what is the warranty period of a normal scan? J Am Coll Cardiol. 2003;41:1329-1340. (Pubitemid 36438995)
4. Berman DS, Kang X, Slomka PJ, et al. Underestimation of extent of ischemia by gated SPECT myocardial perfusion imaging in patients with left main coronary artery disease. J Nucl Cardiol. 2007;14:521-528. (Pubitemid 47163572)
5. Ziadi MC, deKemp RA, Williams K, et al. Does quantification of myocardial flow reserve using rubidium-82 positron emission tomography facilitate detection of multivessel coronary artery disease? J Nucl Cardiol. 2012;19:670-680.
6. Parkash R, deKemp RA, Ruddy TD, et al. Potential utility of rubidium 82 PET quantification in patients with 3-vessel coronary artery disease. J Nucl Cardiol. 2004;11:440-449. (Pubitemid 39115288)
7. Tio RA, Dabeshlim A, Siebelink H-MJ, et al. Comparison between the prognostic value of left ventricular function and myocardial perfusion reserve in patients with ischemic heart disease. J Nucl Med. 2009;50:214-219.
8. 13N-ammonia myocardial perfusion positron emission tomography: added value of coronary flow reserve. J Am Coll Cardiol. 2009;54:150-156.
9. Murthy VL, Naya M, Foster CR, et al. Improved cardiac risk assessment with noninvasive measures of coronary flow reserve. Circulation. 2011;124:2215-2224.
10. Taki J, Fujino S, Nakajima K, et al. Tc-99m retention characteristics during pharmacological hyperemia in human myocardium: comparison with coronary flow reserve measured by Doppler flowire. J Nucl Med. 2001;42:1457-1463. (Pubitemid 32953123)
11. Ito Y, Katoh C, Noriyasu K, et al. Estimation of myocardial blood flow and myocardial flow reserve by 99m-technetium sestamibi imaging: comparison with the results of 15 H2O PET. Eur J Nucl Med Mol Imaging. 2003;30:281-287. (Pubitemid 36686848)
12. Storto G, Cirillo P, Vicario ML, et al. Estimation of coronary flow reserve by Tc-99m sestamibi imaging in patients with coronary artery disease: comparison with the results of intracoronary Doppler technique. J Nucl Cardiol. 2004;11:682-688. (Pubitemid 40012040)
13. Storto G, Soricelli A, Pellegrino T, Petretta M, Cuocolo A. Assessment of the arterial input function for estimation of coronary flow reserve by single photon emission computed tomography: comparison of two different approaches. Eur J Nucl Med Mol Imaging. 2009;36:2034-2041.
14. Marini C, Giusti M, Armonino R, et al. Reduced coronary flow reserve in patients with primary hyperparathyroidism: a study by G-SPECT myocardial perfusion imaging. Eur J Nucl Med Mol Imaging. 2010;37:2256-2263.
15. Daniele S, Nappi C, Acampa W, et al. Incremental prognostic value of coronary flow reserve assessed with single-photon emission computed tomography. J Nucl Cardiol. 2011;18:612-619.
16. Iida H, Eberl S. Quantitative assessment of regional myocardial blood flow with thallium-201 and SPECT. J Nucl Cardiol. 1998;5:313-331. (Pubitemid 28333895)
17. Christian TF, Peters K, Keck B, Allen J, Owens T, Borah B. Gated SPECT imaging to detect changes in myocardial blood flow during progressive coronary occlusion. Int J Cardiovasc Imaging. 2008;24:269-276.
18. 201Tl and dynamic SPECT in canine: optimization and validation of kinetic modeling. Eur J Nucl Med Mol Imaging. 2008;35:896-905.
19. Stabin MG. Radiopharmaceuticals for nuclear cardiology: radiation dosimetry, uncertainties and risk. J Nucl Med. 2008;49:1555-1563.
20. Radiation dose to patients from radiopharmaceuticals (addendum to ICRP publication 53): ICRP publication 80. Ann ICRP. 1998;28.
21. Sitek A, Gullberg GT, Huesman RH. Correction for ambiguous solutions in factor analysis using a penalized least squares objective. IEEE Trans Med Imaging. 2002;21:216-225. (Pubitemid 34630839)
22. Nakazato R, Tamarappoo BK, Kang X, et al. Quantitative upright-supine high-speed SPECT myocardial perfusion imaging for detection of coronary artery disease: correlation with invasive coronary angiography. J Nucl Med. 2010;51:1724-1731.
23. Sharir T, Slomka PJ, Hayes SW, et al. Multicenter trial of high-speed versus conventional single-photon emission computed tomography imaging. J Am Coll Cardiol. 2010;55:1965-1974.
24. Giri S, Shaw LJ, Murthy DR, et al. Impact of diabetes on the risk stratification using stress single-photon emission computed tomography myocardial perfusion imaging in patients with symptoms suggestive of coronary artery disease. Circulation. 2002;105:32-40. (Pubitemid 34049139)
25. Al-Mallah MH, Hachamovitch R, Dorbala S, Di Carli F. Incremental prognostic value of myocardial perfusion imaging in patients referred for stress single-photon emission computed tomography with renal dysfunction. Circ Cardiovasc Imaging. 2009;2:429-436.
26. Murthy VL, Naya M, Foster CR, et al. Coronary vascular dysfunction and prognosis in patients with chronic renal disease. J Am Coll Cardiol Imaging. 2012;5:1025-1034.
27. Murthy VL, Naya M, Foster CR, et al. Association between coronary vascular dysfunction and cardiac mortality in patients with and without diabetes mellitus. Circulation. 2012;126:1858-1868.
28. Yoshinaga K, Chow BJ, deKemp RA, et al. What is the prognostic value of myocardial perfusion imaging using rubidium-82 positron emission tomography? J Am Coll Cardiol. 2006;48:1029-1039. (Pubitemid 44292462)
29. Czernin J, Muller P, Chan S, et al. Influence of age and hemodynamics on myocardial blood flow and flow reserve. Circulation. 1993;88:62-69. (Pubitemid 23195433)
30. Gould KL, Martucci JP, Goldberg DI, et al. Short-term cholesterol lowering decreases size and severity of perfusion abnormalities by positron emission tomography after dipyridamole in patients with coronary artery disease: a potential noninvasive marker of healing coronary endothelium. Circulation. 1994;89:1530-1538.
31. Kaufmann PA, Gnecchi-Ruscone T, Di TM, Schafers KP, Luscher TF, Camici PG. Coronary heart disease in smokers: vitamin C restores coronary microcirculatory function. Circulation. 2000;102:1233-1238.
32. Ziadi MC, Beanlands RSB. The clinical utility of assessing myocardial blood flow using positron emission tomography. J Nucl Cardiol. 2010;17:571-581.
33. Smith AM, Gullberg GT, Christian PE, Datz FL. Kinetic modeling of teboroxime using dynamic SPECT imaging of a canine model. J Nucl Med. 1994;35:484-495. (Pubitemid 24079984)
34. DiBella EVR, Khare HS, Kadrmas DJ, Gullberg GT. SPECT imaging of teboroxime during myocardial blood flow changes. IEEE Trans Nucl Sci. 2000;47:1112-1117.
35. Di Bella EVR, Ross SG, Kadrmas DJ, et al. Compartmental modeling of technetium-99m-labeled teboroxime with dynamic single-photon-emission computed tomography: comparison with static thallium-201 in a canine model. Invest Radiol. 2001;36:178-185. (Pubitemid 32209630)
36. Sugihara H, Yonekura Y, Katoka K, Fukai D, Kitamura N, Tamiguchi Y. Estimation of coronary flow reserve with the use of dynamic SPECT images of Tc-99m tetrofosmin. J Nucl Cardiol. 2001;8:575-579. (Pubitemid 32982778)