The emerging role of MRI in quantitative renal glomerular morphology

American Journal of Physiology - Renal Physiology

Volumn 304, Issue 10, 2013, Pages 1252-1257

  Bennett, K M ^a   Bertram, John F ^b   Beeman, Scott C ^c   Gretz, Norbert ^d  

^a University of Hawaii ^*  (United States)

^b MONASH UNIVERSITY   (Australia)

^c AZ 85281   (United States)

^d UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Glomerular counting; Glomerular filtration rate; Glomerular sizing; Kidney; Magnetic resonance imaging; MRI; Stereology

Indexed keywords

FERRITIN;

CHRONIC KIDNEY DISEASE; GLOMERULOSCLEROSIS; GLOMERULUS; GLOMERULUS BASEMENT MEMBRANE; HISTOLOGY; HUMAN; IMAGE ANALYSIS; IMMUNOHISTOCHEMISTRY; KIDNEY STRUCTURE; KIDNEY TUBULE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; PROTEIN BINDING; QUANTITATIVE ANALYSIS; REVIEW;

EID: 84878636182     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00714.2012     Document Type: Review

References (34)

1. Abercrombie M. Estimation of nuclear population from microtome sections. Anat Rec 94: 239-247, 1946.
2. Badea CT, Drangova M, Holdsworth DW, Johnson GA. In vivo small-animal imaging using micro-CT and digital subtraction angiogra-phy. Phys Med Biol 53: R319-R350, 2008.
3. Batsford SR, Sasaki M, Takamiya H, Vogt A. Cationic macromolecule-induced nephrotic syndrome in rabbits. Lack of immune complex involvement. Lab Invest 49: 260-269, 1983.
4. Beeman SC, Georges JF, Bennett KM. Toxicity, biodistribution, and ex vivo MRI detection of intravenously injected cationized ferritin. Magn Reson Med 69: 853-861, 2013.
5. Beeman SC, Zhang M, Gubhaju L, Wu T, Bertram JF, Frakes DH, Cherry BR, Bennett KM. Measuring glomerular number and size in perfused kidneys using MRI. Am J Physiol Renal Physiol 300: F1454- F1457, 2011.
6. Bennett KM, Zhou H, Sumner JP, Dodd SJ, Bouraoud N, Doi K, Star RA, Koretsky AP. MRI of the basement membrane using charged nanoparticles as contrast agents. Magn Reson Med 60: 564-574, 2008.
7. Bertram JF, Douglas-Denton RN, Diouf B, Hughson MD, Hoy WE. Human nephron number: implications for health and disease. Pediatr Nephrol 26: 1529-1533, 2011.
8. Bertram JF, Soosaipillai MC, Ricardo SD, Ryan GB. Total numbers of glomeruli and individual glomerular cell types in the normal rat kidney. Cell Tissue Res 270: 37-45, 1992.
9. Bertram JF. Analyzing renal glomeruli with the new stereology. Int Rev Cytol 161: 111-172, 1995.
10. Brenner B, Garcia DL, Anderson S. Less of one, more of the other? Am J Hypertens 1: 335-347, 1988.
11. Bulte JW, Douglas T, Mann S, Frankel RB, Moskowitz BM, Brooks RA, Baumgarner CD, Vymazal J, Strub MP, Frank JA. Magnetofer-ritin: characterization of a novel superparamagnetic MR contrast agent. J Magn Reson Imaging 4: 497-505, 1994.
12. Chevalier RL, Forbes MS. Generation and evolution of atubular glom-eruli in the progression of renal disorders. J Am Soc Nephrol 19: 197-206, 2008.
13. Clavijo-Jordan V, Caplan MR, Bennett KM. Simplified synthesis and relaxometry of magnetoferrin for magnetic resonance imaging. Magn Reson Med 64: 1260-1266, 2010.
14. Cohen B, Dafni H, Meir G, Harmelin A, Neeman M. Ferritin as an endogenous MRI reporter for noninvasive imaging of gene expression in C6 glioma tumors. Neoplasia 7: 109-117, 2005.
15. Danon D, Goldstein L, Marikovsky Y, Skutelsky E. Use of cationized ferritin as a label of negative charges on cell surfaces. J Ultrastruct Res 38: 500-510, 1972.
16. DeHoff R, Rhines F. Determination of number of particles per unit volume from measurements made on random plane sections: the general cylinder and the ellipsoid. Trans Metall Soc AIME, 1961.
17. Floderus S. Untersuchungen uber den Bau der menschlichen hypophse mit besondener Berucksichtigung der quantitativen mikromorphologis-chen Verhaltnisse. Acta Pathol Microbiol Scand 53: 1-276, 1944.
18. Genove G, DeMarco U, Xu H, Goins WF, Ahrens ET. A new transgene reporter for in vivo magnetic resonance imaging. Nat Med 11: 450-454, 2005.
19. Gossuin Y, Muller R, Gillis P, Bartel L. Relaxivities of human liver and spleen ferritin. Magn Reson Imaging 23: 1001-1004, 2005.
20. Heilmann M, Neudecker S, Wolf I, Gubhaju L, Sticht C, Schock-Kusch D, Kriz W, Bertram JF, Schad LR, Gretz N. Quantification of glomerular number and size distribution in normal rat kidneys using magnetic resonance imaging. Nephrol Dial Transplant 27: 100-107, 2012.
21. Hoy WE, Hughson MD, Zimanyi M, Samuel T, Douglas-Denton R, Holden L, Mott S, Bertram JF. Distribution of volumes of individual glomeruli in kidneys at autopsy: association with age, nephron number, birth weight and body mass index. Clin Nephrol 74, Suppl 1: S105-12, 2010.
22. Kubosawa H, Nakayama H, Sano T, Kondo Y. Morphological alterations of glomerulus induced by infusion of cationized ferritin. Acta Pathol Jpn 43: 445-455, 1993.
23. Marcussen N. Atubular glomeruli and the structural basis for chronic renal failure. Lab Invest 66: 265-284, 1992.
24. Heywood BR, Mann S, Meldrum FC. Magnetoferritin: in vitro synthesis of a novel magnetic protein. Science 257: 522-523, 1992.
25. Moritz KM, Wintour EM, Black MJ, Bertram JF, Caruana G. Factors influencing mammalian kidney development: implications for health in adult life. Adv Anat Embryol Cell Biol 196: 1-78, 2008.
26. Pedersen M, Karstoft K, Lødrup A, Jespersen B, Nyengaard JR. Advantages and controversies in the era of intrarenal volumetry. Am J Nephrol 33, Suppl 1: 40-45, 2011.
27. Puelles VG, Zimanyi MA, Samuel T, Hughson MD, Douglas-Denton RN, Bertram JF, Armitage JA. Estimating individual glomerular volume in the human kidney: clinical perspectives. Nephrol Dial Transplant 27: 1880-1888, 2012.
28. Qian C, Murphy-Boesch J, Dodd S, Koretsky A. Sensitivity enhancement of remotely coupled NMR detectors using wirelessly powered parametric amplification. Magn Reson Med 68: 989-996, 2012.
29. Qian C, Yu X, Chen DY, Dodd S, Bouraoud N, Pothayee N, Chen Y, Beeman S, Bennett K, Murphy-Boesch J, Koretsky A. Wireless Amplified Nuclear MR Detector (WAND) for high-spatial-resolution MR imaging of internal organs: preclinical demonstration in a rodent model. Radiology 2013 Feb 7 [Epub ahead of print].
30. Qian C, Zabow G, Koretsky A. Engineering novel detectors and sensors for MRI. J Magn Reson 229: 67-74, 2013.
31. Sterio DC. The unbiased estimation of number and sizes of arbitrary particles using the disector. J Microsc 134: 127-136, 1984.
32. Uchida M, Terashima M, Cunningham CH, Suzuki Y, Willits DA, Willis AF, Yang PC, Tsao PS, McConnell MV, Young MJ, Douglas T. A human ferritin iron oxide nano-composite magnetic resonance contrast agent. Magn Reson Med 60: 1073-1081, 2008.
33. Weibel ER, Gomez DM. A principle for counting tissue structures on random sections. J Appl Physiol 17: 343-348, 1962.
34. Xie L, Cianciolo RE, Hulette B, Lee HW, Qi Y, Cofer G, Johnson GA. Magnetic resonance histology of age-related nephropathy in the Sprague Dawley rat. Toxicol Pathol 40: 764-778, 2012.