Expression of the bmp receptor alk3 in the second heart field is essential for development of the dorsal mesenchymal protrusion and atrioventricular septation

Circulation Research

Volumn 112, Issue 11, 2013, Pages 1420-1432

  Briggs, Laura E ^a   Phelps, Aimee L ^a   Brown, Elizabeth ^a   Kakarla, Jayant ^b   Anderson, Robert H ^a,b   Van Den Hoff, Maurice J B ^c   Wessels, Andy ^a,c  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b NEWCASTLE UNIVERSITY   (United Kingdom)

^c ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

Alk3; atrial septal defect; atrioventricular septal defect; bone morphogenetic protein; dorsal mesenchymal protrusion

Indexed keywords

BIOLOGICAL MARKER; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 4; BONE MORPHOGENETIC PROTEIN RECEPTOR 1A; OSTEOGENIC PROTEIN 1; SMAD1 PROTEIN; SMAD5 PROTEIN; SMAD8 PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ATRIOVENTRICULAR SEPTAL DEFECT; CELL PROLIFERATION; DORSAL MESENCHYMAL PROTRUSION; HEART; HEART DEVELOPMENT; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ALK3; ATRIAL SEPTAL DEFECT; ATRIOVENTRICULAR SEPTAL DEFECT; BONE MORPHOGENETIC PROTEIN; DORSAL MESENCHYMAL PROTRUSION;

ANIMALS; ATRIAL SEPTUM; BONE MORPHOGENETIC PROTEIN RECEPTORS, TYPE I; BONE MORPHOGENETIC PROTEINS; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GREEN FLUORESCENT PROTEINS; HEART SEPTAL DEFECTS; HEART SEPTAL DEFECTS, ATRIAL; MALE; MESODERM; MICE; MICE, 129 STRAIN; MICE, KNOCKOUT; MYOCARDIUM; PREGNANCY; SIGNAL TRANSDUCTION; VENTRICULAR SEPTUM;

EID: 84878634760     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.112.300821     Document Type: Article

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