Independent and epistatic effects of variants in VPS10-d receptors on Alzheimer disease risk and processing of the amyloid precursor protein (APP)

Translational Psychiatry

Volumn 3, Issue , 2013, Pages

  Reitz, C ^a,b,c   Tosto, G ^b   Vardarajan, B ^d   Rogaeva, E ^e   Ghani, M ^e   Rogers, R S ^b   Conrad, C ^b   Haines, J L ^f   Pericak Vance, M A ^g   Fallin, M D ^h   Foroud, T ⁱ   Farrer, L A ^d,j   Schellenberg, G D ^k   George Hyslop, P S ^e,l,m   Mayeux, R ^a,b,c,n  

^a NewYork Presbyterian Hospital   (United States)

^b Taub Institute for Research on Alzheimer's Disease and the Aging Brain and the Gertrude H Sergievsky Center   (United States)

^c University of Toronto ^*  (United States)

^d BOSTON UNIVERSITY   (United States)

^e UNIVERSITY OF TORONTO   (Canada)

^f VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^h JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

ⁱ INDIANA UNIVERSITY   (United States)

^j BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^k UNIVERSITY OF PENNSYLVANIA   (United States)

^l UNIVERSITY HEALTH NETWORK   (Canada)

^m UNIVERSITY OF CAMBRIDGE   (United Kingdom)

ⁿ Och Spine at New York Presbyterian Hospitals   (United States)

more..

Author keywords

Alzheimer's disease; SORCS2; SORCS3; SORT1

Indexed keywords

AMYLOID PRECURSOR PROTEIN; GAMMA SECRETASE; NEUROPEPTIDE RECEPTOR; SHORT HAIRPIN RNA; SORCS1 PROTEIN; SORCS2 PROTEIN; SORCS3 PROTEIN; SORTILIN; UNCLASSIFIED DRUG; VPS10 PROTEIN; CELL SURFACE RECEPTOR; SORCS1 PROTEIN, HUMAN; SORCS2 PROTEIN, HUMAN; SORCS3 PROTEIN, HUMAN; VESICULAR TRANSPORT ADAPTOR PROTEIN;

ALZHEIMER DISEASE; ARTICLE; CASE CONTROL STUDY; CAUCASIAN; CONCENTRATION (PARAMETERS); ENZYME ACTIVITY; EPISTASIS; FEMALE; GENE EXPRESSION; GENE SILENCING; GENETIC ASSOCIATION; GENETIC RISK; GENETIC VARIABILITY; HUMAN; HUMAN CELL; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; MICROARRAY ANALYSIS; ONSET AGE; PROTEIN DOMAIN; PROTEIN PROCESSING; RISK ASSESSMENT; SINGLE NUCLEOTIDE POLYMORPHISM; STATISTICAL MODEL; AGED; DNA MICROARRAY; GENETIC PREDISPOSITION; GENETICS; METABOLISM; POLYMERASE CHAIN REACTION; RISK FACTOR;

ADAPTOR PROTEINS, VESICULAR TRANSPORT; AGED; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; CASE-CONTROL STUDIES; EPISTASIS, GENETIC; GENETIC PREDISPOSITION TO DISEASE; HUMANS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, CELL SURFACE; RECEPTORS, NEUROPEPTIDE; RISK FACTORS;

EID: 84878632939     PISSN: None     EISSN: 21583188     Source Type: Journal    
DOI: 10.1038/tp.2013.13     Document Type: Article

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