-
1
-
-
3442882179
-
Immunogenicity of constitutively active V599EBRaf
-
10.1158/0008-5472.CAN-04-0937 15289355 10.1158/0008-5472.CAN-04-0937 1:CAS:528:DC%2BD2cXmtF2lsr8%3D
-
Andersen MH, Fensterle J, Ugurel S, Reker S, Houben R, Guldberg P, Berger TG, Schadendorf D, Trefzer U, Brocker EB, Straten P, Rapp UR, Becker JC (2004) Immunogenicity of constitutively active V599EBRaf. Cancer Res 64(15):5456-5460. doi: 10.1158/0008-5472.CAN-04-0937
-
(2004)
Cancer Res
, vol.64
, Issue.15
, pp. 5456-5460
-
-
Andersen, M.H.1
Fensterle, J.2
Ugurel, S.3
Reker, S.4
Houben, R.5
Guldberg, P.6
Berger, T.G.7
Schadendorf, D.8
Trefzer, U.9
Brocker, E.B.10
Straten, P.11
Rapp, U.R.12
Becker, J.C.13
-
2
-
-
0034951252
-
Mutational analysis of TSC1 and TSC2 genes in gangliogliomas
-
11437991 10.1046/j.0305-1846.2001.00302.x 1:CAS:528:DC%2BD3MXltlKnsro%3D
-
Becker AJ, Lobach M, Klein H, Normann S, Nothen MM, von Deimling A, Mizuguchi M, Elger CE, Schramm J, Wiestler OD, Blumcke I (2001) Mutational analysis of TSC1 and TSC2 genes in gangliogliomas. Neuropathol Appl Neurobiol 27(2):105-114
-
(2001)
Neuropathol Appl Neurobiol
, vol.27
, Issue.2
, pp. 105-114
-
-
Becker, A.J.1
Lobach, M.2
Klein, H.3
Normann, S.4
Nothen, M.M.5
Von Deimling, A.6
Mizuguchi, M.7
Elger, C.E.8
Schramm, J.9
Wiestler, O.D.10
Blumcke, I.11
-
3
-
-
84873715417
-
Detection of the BRAF V600E mutation in serous ovarian tumors: A comparative analysis of immunohistochemistry with a mutation-specific monoclonal antibody and allele-specific PCR
-
doi: 10.1016/j.humpath.2012.07.010
-
Bosmuller H, Fischer A, Pham DL, Fehm T, Capper D, von Deimling A, Bonzheim I, Staebler A, Fend F (2012) Detection of the BRAF V600E mutation in serous ovarian tumors: a comparative analysis of immunohistochemistry with a mutation-specific monoclonal antibody and allele-specific PCR. Hum Pathol doi: 10.1016/j.humpath.2012.07.010
-
(2012)
Hum Pathol
-
-
Bosmuller, H.1
Fischer, A.2
Pham, D.L.3
Fehm, T.4
Capper, D.5
Von Deimling, A.6
Bonzheim, I.7
Staebler, A.8
Fend, F.9
-
4
-
-
33947574174
-
Clinical and molecular characteristics of malignant transformation of low-grade glioma in children
-
10.1200/JCO.2006.06.8213 17308273 10.1200/JCO.2006.06.8213 1:CAS:528:DC%2BD2sXjt1Kgu7Y%3D
-
Broniscer A, Baker SJ, West AN, Fraser MM, Proko E, Kocak M, Dalton J, Zambetti GP, Ellison DW, Kun LE, Gajjar A, Gilbertson RJ, Fuller CE (2007) Clinical and molecular characteristics of malignant transformation of low-grade glioma in children. J Clin Oncol 25(6):682-689. doi: 10.1200/JCO.2006.06.8213
-
(2007)
J Clin Oncol
, vol.25
, Issue.6
, pp. 682-689
-
-
Broniscer, A.1
Baker, S.J.2
West, A.N.3
Fraser, M.M.4
Proko, E.5
Kocak, M.6
Dalton, J.7
Zambetti, G.P.8
Ellison, D.W.9
Kun, L.E.10
Gajjar, A.11
Gilbertson, R.J.12
Fuller, C.E.13
-
5
-
-
84869220840
-
Utilization of a MAB for BRAFV600E detection in papillary thyroid carcinoma
-
10.1530/ERC-12-0239 22997209 10.1530/ERC-12-0239 1:CAS:528: DC%2BC3sXhsFCitbc%3D
-
Bullock M, O'Neill C, Chou A, Clarkson A, Dodds T, Toon C, Sywak M, Sidhu SB, Delbridge LW, Robinson BG, Learoyd DL, Capper D, von Deimling A, Clifton-Bligh RJ, Gill AJ (2012) Utilization of a MAB for BRAFV600E detection in papillary thyroid carcinoma. Endocr Relat Cancer 19(6):779-784. doi: 10.1530/ERC-12-0239
-
(2012)
Endocr Relat Cancer
, vol.19
, Issue.6
, pp. 779-784
-
-
Bullock, M.1
O'Neill, C.2
Chou, A.3
Clarkson, A.4
Dodds, T.5
Toon, C.6
Sywak, M.7
Sidhu, S.B.8
Delbridge, L.W.9
Robinson, B.G.10
Learoyd, D.L.11
Capper, D.12
Von Deimling, A.13
Clifton-Bligh, R.J.14
Gill, A.J.15
-
6
-
-
84857030136
-
Immunohistochemical testing of BRAF V600E status in 1,120 tumor tissue samples of patients with brain metastases
-
10.1007/s00401-011-0887-y 22012135 10.1007/s00401-011-0887-y 1:CAS:528:DC%2BC38XpslyktA%3D%3D
-
Capper D, Berghoff AS, Magerle M, Ilhan A, Wohrer A, Hackl M, Pichler J, Pusch S, Meyer J, Habel A, Petzelbauer P, Birner P, von Deimling A, Preusser M (2012) Immunohistochemical testing of BRAF V600E status in 1,120 tumor tissue samples of patients with brain metastases. Acta Neuropathol 123(2):223-233. doi: 10.1007/s00401-011-0887-y
-
(2012)
Acta Neuropathol
, vol.123
, Issue.2
, pp. 223-233
-
-
Capper, D.1
Berghoff, A.S.2
Magerle, M.3
Ilhan, A.4
Wohrer, A.5
Hackl, M.6
Pichler, J.7
Pusch, S.8
Meyer, J.9
Habel, A.10
Petzelbauer, P.11
Birner, P.12
Von Deimling, A.13
Preusser, M.14
-
7
-
-
79959580390
-
Assessment of BRAF V600E mutation status by immunohistochemistry with a mutation-specific monoclonal antibody
-
10.1007/s00401-011-0841-z 21638088 10.1007/s00401-011-0841-z 1:CAS:528:DC%2BC3MXnvVKnsr0%3D
-
Capper D, Preusser M, Habel A, Sahm F, Ackermann U, Schindler G, Pusch S, Mechtersheimer G, Zentgraf H, von Deimling A (2011) Assessment of BRAF V600E mutation status by immunohistochemistry with a mutation-specific monoclonal antibody. Acta Neuropathol 122(1):11-19. doi: 10.1007/s00401-011-0841-z
-
(2011)
Acta Neuropathol
, vol.122
, Issue.1
, pp. 11-19
-
-
Capper, D.1
Preusser, M.2
Habel, A.3
Sahm, F.4
Ackermann, U.5
Schindler, G.6
Pusch, S.7
Mechtersheimer, G.8
Zentgraf, H.9
Von Deimling, A.10
-
8
-
-
84872818282
-
Dual-specificity MAP kinase phosphatases (MKPs): Shaping the outcome of MAP kinase signalling
-
10.1111/j.1742-4658.2012.08716.x 22812510
-
Caunt CJ, Keyse SM (2012) Dual-specificity MAP kinase phosphatases (MKPs): shaping the outcome of MAP kinase signalling. FEBS J. doi: 10.1111/j.1742-4658.2012.08716.x
-
(2012)
FEBS J
-
-
Caunt, C.J.1
Keyse, S.M.2
-
9
-
-
84875410796
-
Detection of BRAF p.V600E mutations in melanomas: Comparison of four methods argues for sequential use of immunohistochemistry and pyrosequencing
-
10.1016/j.jmoldx.2012.09.001 23159108 10.1016/j.jmoldx.2012.09.001 1:CAS:528:DC%2BC3sXhs1elt7o%3D
-
Colomba E, Helias-Rodzewicz Z, Von Deimling A, Marin C, Terrones N, Pechaud D, Surel S, Cote JF, Peschaud F, Capper D, Blons H, Zimmermann U, Clerici T, Saiag P, Emile JF (2013) Detection of BRAF p.V600E mutations in melanomas: comparison of four methods argues for sequential use of immunohistochemistry and pyrosequencing. J Mol Diagn 15(1):94-100. doi: 10.1016/j.jmoldx.2012.09.001
-
(2013)
J Mol Diagn
, vol.15
, Issue.1
, pp. 94-100
-
-
Colomba, E.1
Helias-Rodzewicz, Z.2
Von Deimling, A.3
Marin, C.4
Terrones, N.5
Pechaud, D.6
Surel, S.7
Cote, J.F.8
Peschaud, F.9
Capper, D.10
Blons, H.11
Zimmermann, U.12
Clerici, T.13
Saiag, P.14
Emile, J.F.15
-
10
-
-
18444374405
-
Mutations of the BRAF gene in human cancer
-
10.1038/nature00766 12068308 10.1038/nature00766 1:CAS:528: DC%2BD38XkvVagsLo%3D
-
Davies H, Bignell GR, Cox C, Stephens P, Edkins S, Clegg S, Teague J, Woffendin H, Garnett MJ, Bottomley W, Davis N, Dicks E, Ewing R, Floyd Y, Gray K, Hall S, Hawes R, Hughes J, Kosmidou V, Menzies A, Mould C, Parker A, Stevens C, Watt S, Hooper S, Wilson R, Jayatilake H, Gusterson BA, Cooper C, Shipley J, Hargrave D, Pritchard-Jones K, Maitland N, Chenevix-Trench G, Riggins GJ, Bigner DD, Palmieri G, Cossu A, Flanagan A, Nicholson A, Ho JW, Leung SY, Yuen ST, Weber BL, Seigler HF, Darrow TL, Paterson H, Marais R, Marshall CJ, Wooster R, Stratton MR, Futreal PA (2002) Mutations of the BRAF gene in human cancer. Nature 417(6892):949-954. doi: 10.1038/nature00766
-
(2002)
Nature
, vol.417
, Issue.6892
, pp. 949-954
-
-
Davies, H.1
Bignell, G.R.2
Cox, C.3
Stephens, P.4
Edkins, S.5
Clegg, S.6
Teague, J.7
Woffendin, H.8
Garnett, M.J.9
Bottomley, W.10
Davis, N.11
Dicks, E.12
Ewing, R.13
Floyd, Y.14
Gray, K.15
Hall, S.16
Hawes, R.17
Hughes, J.18
Kosmidou, V.19
Menzies, A.20
Mould, C.21
Parker, A.22
Stevens, C.23
Watt, S.24
Hooper, S.25
Wilson, R.26
Jayatilake, H.27
Gusterson, B.A.28
Cooper, C.29
Shipley, J.30
Hargrave, D.31
Pritchard-Jones, K.32
Maitland, N.33
Chenevix-Trench, G.34
Riggins, G.J.35
Bigner, D.D.36
Palmieri, G.37
Cossu, A.38
Flanagan, A.39
Nicholson, A.40
Ho, J.W.41
Leung, S.Y.42
Yuen, S.T.43
Weber, B.L.44
Seigler, H.F.45
Darrow, T.L.46
Paterson, H.47
Marais, R.48
Marshall, C.J.49
Wooster, R.50
Stratton, M.R.51
Futreal, P.A.52
more..
-
11
-
-
78651328442
-
Malignant ganglioglioma: Case report and review of literature
-
10.1007/s11060-010-0248-z 20524041 10.1007/s11060-010-0248-z
-
DeMarchi R, Abu-Abed S, Munoz D, Loch Macdonald R (2011) Malignant ganglioglioma: case report and review of literature. J Neurooncol 101(2):311-318. doi: 10.1007/s11060-010-0248-z
-
(2011)
J Neurooncol
, vol.101
, Issue.2
, pp. 311-318
-
-
Demarchi, R.1
Abu-Abed, S.2
Munoz, D.3
Loch MacDonald, R.4
-
12
-
-
79953184268
-
BRAF V600E mutations are common in pleomorphic xanthoastrocytoma: Diagnostic and therapeutic implications
-
10.1371/journal.pone.0017948 21479234 10.1371/journal.pone.0017948 1:CAS:528:DC%2BC3MXks1KktL8%3D
-
Dias-Santagata D, Lam Q, Vernovsky K, Vena N, Lennerz JK, Borger DR, Batchelor TT, Ligon KL, Iafrate AJ, Ligon AH, Louis DN, Santagata S (2011) BRAF V600E mutations are common in pleomorphic xanthoastrocytoma: diagnostic and therapeutic implications. PLoS One 6(3):e17948. doi: 10.1371/journal.pone. 0017948
-
(2011)
PLoS One
, vol.6
, Issue.3
, pp. 17948
-
-
Dias-Santagata, D.1
Lam, Q.2
Vernovsky, K.3
Vena, N.4
Lennerz, J.K.5
Borger, D.R.6
Batchelor, T.T.7
Ligon, K.L.8
Iafrate, A.J.9
Ligon, A.H.10
Louis, D.N.11
Santagata, S.12
-
13
-
-
78149467927
-
Activating mutations in BRAF characterize a spectrum of pediatric low-grade gliomas
-
10.1093/neuonc/noq007 20156809 10.1093/neuonc/noq007 1:CAS:528: DC%2BC3cXps1WksL0%3D
-
Dougherty MJ, Santi M, Brose MS, Ma C, Resnick AC, Sievert AJ, Storm PB, Biegel JA (2010) Activating mutations in BRAF characterize a spectrum of pediatric low-grade gliomas. Neuro Oncol 12(7):621-630. doi: 10.1093/neuonc/noq007
-
(2010)
Neuro Oncol
, vol.12
, Issue.7
, pp. 621-630
-
-
Dougherty, M.J.1
Santi, M.2
Brose, M.S.3
Ma, C.4
Resnick, A.C.5
Sievert, A.J.6
Storm, P.B.7
Biegel, J.A.8
-
14
-
-
2942552470
-
Unlocking the code of 14-3-3
-
10.1242/jcs.01171 15090593 10.1242/jcs.01171 1:CAS:528: DC%2BD2cXksVykurc%3D
-
Dougherty MK, Morrison DK (2004) Unlocking the code of 14-3-3. J Cell Sci 117(Pt 10):1875-1884. doi: 10.1242/jcs.01171
-
(2004)
J Cell Sci
, vol.117
, Issue.PART 10
, pp. 1875-1884
-
-
Dougherty, M.K.1
Morrison, D.K.2
-
15
-
-
33845592531
-
NRAS and BRAF mutations in melanoma tumours in relation to clinical characteristics: A study based on mutation screening by pyrosequencing
-
10.1097/01.cmr.0000232300.22032.86 17119447 10.1097/01.cmr.0000232300. 22032.86 1:CAS:528:DC%2BD28Xht1antrvL
-
Edlundh-Rose E, Egyhazi S, Omholt K, Mansson-Brahme E, Platz A, Hansson J, Lundeberg J (2006) NRAS and BRAF mutations in melanoma tumours in relation to clinical characteristics: a study based on mutation screening by pyrosequencing. Melanoma Res 16(6):471-478. doi: 10.1097/01.cmr.0000232300. 22032.86
-
(2006)
Melanoma Res
, vol.16
, Issue.6
, pp. 471-478
-
-
Edlundh-Rose, E.1
Egyhazi, S.2
Omholt, K.3
Mansson-Brahme, E.4
Platz, A.5
Hansson, J.6
Lundeberg, J.7
-
16
-
-
80052273582
-
Functional characterization of a BRAF insertion mutant associated with pilocytic astrocytoma
-
10.1002/ijc.25893 21190184 10.1002/ijc.25893 1:CAS:528: DC%2BC3MXhtFSjsb%2FJ
-
Eisenhardt AE, Olbrich H, Roring M, Janzarik W, Anh TN, Cin H, Remke M, Witt H, Korshunov A, Pfister SM, Omran H, Brummer T (2011) Functional characterization of a BRAF insertion mutant associated with pilocytic astrocytoma. Int J Cancer 129(9):2297-2303. doi: 10.1002/ijc.25893
-
(2011)
Int J Cancer
, vol.129
, Issue.9
, pp. 2297-2303
-
-
Eisenhardt, A.E.1
Olbrich, H.2
Roring, M.3
Janzarik, W.4
Anh, T.N.5
Cin, H.6
Remke, M.7
Witt, H.8
Korshunov, A.9
Pfister, S.M.10
Omran, H.11
Brummer, T.12
-
17
-
-
66849099801
-
Activation of the ERK/MAPK pathway: A signature genetic defect in posterior fossa pilocytic astrocytomas
-
10.1002/path.2558 19373855 10.1002/path.2558 1:CAS:528: DC%2BD1MXms1Kiu7w%3D
-
Forshew T, Tatevossian RG, Lawson AR, Ma J, Neale G, Ogunkolade BW, Jones TA, Aarum J, Dalton J, Bailey S, Chaplin T, Carter RL, Gajjar A, Broniscer A, Young BD, Ellison DW, Sheer D (2009) Activation of the ERK/MAPK pathway: a signature genetic defect in posterior fossa pilocytic astrocytomas. J Pathol 218(2):172-181. doi: 10.1002/path.2558
-
(2009)
J Pathol
, vol.218
, Issue.2
, pp. 172-181
-
-
Forshew, T.1
Tatevossian, R.G.2
Lawson, A.R.3
Ma, J.4
Neale, G.5
Ogunkolade, B.W.6
Jones, T.A.7
Aarum, J.8
Dalton, J.9
Bailey, S.10
Chaplin, T.11
Carter, R.L.12
Gajjar, A.13
Broniscer, A.14
Young, B.D.15
Ellison, D.W.16
Sheer, D.17
-
18
-
-
0038243934
-
Potential tumor suppressive pathway involving DUSP6/MKP-3 in pancreatic cancer
-
10.1016/S0002-9440(10)64315-5 12759238 10.1016/S0002-9440(10)64315-5 1:CAS:528:DC%2BD3sXkvVyjsbk%3D
-
Furukawa T, Sunamura M, Motoi F, Matsuno S, Horii A (2003) Potential tumor suppressive pathway involving DUSP6/MKP-3 in pancreatic cancer. Am J Pathol 162(6):1807-1815. doi: 10.1016/S0002-9440(10)64315-5
-
(2003)
Am J Pathol
, vol.162
, Issue.6
, pp. 1807-1815
-
-
Furukawa, T.1
Sunamura, M.2
Motoi, F.3
Matsuno, S.4
Horii, A.5
-
19
-
-
0028834247
-
Age-related changes in diagnoses, histological features, and survival in children with brain tumors: 1930-1979. The Childhood Brain Tumor Consortium
-
8584145 10.1227/00006123-199512000-00004 1:STN:280:DyaK287lvF2gtw%3D%3D
-
Gilles FH, Sobel EL, Tavare CJ, Leviton A, Hedley-Whyte ET (1995) Age-related changes in diagnoses, histological features, and survival in children with brain tumors: 1930-1979. The Childhood Brain Tumor Consortium. Neurosurgery 37(6):1056-1068
-
(1995)
Neurosurgery
, vol.37
, Issue.6
, pp. 1056-1068
-
-
Gilles, F.H.1
Sobel, E.L.2
Tavare, C.J.3
Leviton, A.4
Hedley-Whyte, E.T.5
-
20
-
-
69949114447
-
Type and frequency of IDH1 and IDH2 mutations are related to astrocytic and oligodendroglial differentiation and age: A study of 1,010 diffuse gliomas
-
10.1007/s00401-009-0561-9 19554337 10.1007/s00401-009-0561-9
-
Hartmann C, Meyer J, Balss J, Capper D, Mueller W, Christians A, Felsberg J, Wolter M, Mawrin C, Wick W, Weller M, Herold-Mende C, Unterberg A, Jeuken JW, Wesseling P, Reifenberger G, von Deimling A (2009) Type and frequency of IDH1 and IDH2 mutations are related to astrocytic and oligodendroglial differentiation and age: a study of 1,010 diffuse gliomas. Acta Neuropathol 118(4):469-474. doi: 10.1007/s00401-009-0561-9
-
(2009)
Acta Neuropathol
, vol.118
, Issue.4
, pp. 469-474
-
-
Hartmann, C.1
Meyer, J.2
Balss, J.3
Capper, D.4
Mueller, W.5
Christians, A.6
Felsberg, J.7
Wolter, M.8
Mawrin, C.9
Wick, W.10
Weller, M.11
Herold-Mende, C.12
Unterberg, A.13
Jeuken, J.W.14
Wesseling, P.15
Reifenberger, G.16
Von Deimling, A.17
-
21
-
-
80055084211
-
BRAF-KIAA1549 fusion transcripts are less frequent in pilocytic astrocytomas diagnosed in adults
-
10.1111/j.1365-2990.2011.01193.x 21696415 10.1111/j.1365-2990.2011.01193. x 1:CAS:528:DC%2BC3MXhs1KjsbnN
-
Hasselblatt M, Riesmeier B, Lechtape B, Brentrup A, Stummer W, Albert FK, Sepehrnia A, Ebel H, Gerss J, Paulus W (2011) BRAF-KIAA1549 fusion transcripts are less frequent in pilocytic astrocytomas diagnosed in adults. Neuropathol Appl Neurobiol 37(7):803-806. doi: 10.1111/j.1365-2990.2011.01193.x
-
(2011)
Neuropathol Appl Neurobiol
, vol.37
, Issue.7
, pp. 803-806
-
-
Hasselblatt, M.1
Riesmeier, B.2
Lechtape, B.3
Brentrup, A.4
Stummer, W.5
Albert, F.K.6
Sepehrnia, A.7
Ebel, H.8
Gerss, J.9
Paulus, W.10
-
22
-
-
43049133343
-
Comprehensive characterization of genomic aberrations in gangliogliomas by CGH, array-based CGH and interphase FISH
-
10.1111/j.1750-3639.2008.00122.x 18371186 10.1111/j.1750-3639.2008.00122. x 1:CAS:528:DC%2BD1cXovFelsr4%3D
-
Hoischen A, Ehrler M, Fassunke J, Simon M, Baudis M, Landwehr C, Radlwimmer B, Lichter P, Schramm J, Becker AJ, Weber RG (2008) Comprehensive characterization of genomic aberrations in gangliogliomas by CGH, array-based CGH and interphase FISH. Brain Pathol 18(3):326-337. doi: 10.1111/j.1750-3639. 2008.00122.x
-
(2008)
Brain Pathol
, vol.18
, Issue.3
, pp. 326-337
-
-
Hoischen, A.1
Ehrler, M.2
Fassunke, J.3
Simon, M.4
Baudis, M.5
Landwehr, C.6
Radlwimmer, B.7
Lichter, P.8
Schramm, J.9
Becker, A.J.10
Weber, R.G.11
-
23
-
-
80052022841
-
Isocitrate dehydrogenase 1 analysis differentiates gangliogliomas from infiltrative gliomas
-
10.1111/j.1750-3639.2011.00480.x 21314850 1:CAS:528:DC%2BC3MXht1Cru7nN
-
Horbinski C, Kofler J, Yeaney G, Camelo-Piragua S, Venneti S, Louis DN, Perry A, Murdoch G, Nikiforova M (2011) Isocitrate dehydrogenase 1 analysis differentiates gangliogliomas from infiltrative gliomas. Brain Pathol 21(5):564-574. doi: 10.1111/j.1750-3639.2011.00480.x
-
(2011)
Brain Pathol
, vol.21
, Issue.5
, pp. 564-574
-
-
Horbinski, C.1
Kofler, J.2
Yeaney, G.3
Camelo-Piragua, S.4
Venneti, S.5
Louis, D.N.6
Perry, A.7
Murdoch, G.8
Nikiforova, M.9
-
24
-
-
68749098096
-
Duplication of 7q34 is specific to juvenile pilocytic astrocytomas and a hallmark of cerebellar and optic pathway tumours
-
10.1038/sj.bjc.6605179 19603027 10.1038/sj.bjc.6605179 1:CAS:528:DC%2BD1MXpvFyisbo%3D
-
Jacob K, Albrecht S, Sollier C, Faury D, Sader E, Montpetit A, Serre D, Hauser P, Garami M, Bognar L, Hanzely Z, Montes JL, Atkinson J, Farmer JP, Bouffet E, Hawkins C, Tabori U, Jabado N (2009) Duplication of 7q34 is specific to juvenile pilocytic astrocytomas and a hallmark of cerebellar and optic pathway tumours. Br J Cancer 101(4):722-733. doi: 10.1038/sj.bjc.6605179
-
(2009)
Br J Cancer
, vol.101
, Issue.4
, pp. 722-733
-
-
Jacob, K.1
Albrecht, S.2
Sollier, C.3
Faury, D.4
Sader, E.5
Montpetit, A.6
Serre, D.7
Hauser, P.8
Garami, M.9
Bognar, L.10
Hanzely, Z.11
Montes, J.L.12
Atkinson, J.13
Farmer, J.P.14
Bouffet, E.15
Hawkins, C.16
Tabori, U.17
Jabado, N.18
-
25
-
-
79960397029
-
Genetic aberrations leading to MAPK pathway activation mediate oncogene-induced senescence in sporadic pilocytic astrocytomas
-
10.1158/1078-0432.CCR-11-0127 21610151 10.1158/1078-0432.CCR-11-0127 1:CAS:528:DC%2BC3MXovFehtrY%3D
-
Jacob K, Quang-Khuong DA, Jones DT, Witt H, Lambert S, Albrecht S, Witt O, Vezina C, Shirinian M, Faury D, Garami M, Hauser P, Klekner A, Bognar L, Farmer JP, Montes JL, Atkinson J, Hawkins C, Korshunov A, Collins VP, Pfister SM, Tabori U, Jabado N (2011) Genetic aberrations leading to MAPK pathway activation mediate oncogene-induced senescence in sporadic pilocytic astrocytomas. Clin Cancer Res 17(14):4650-4660. doi: 10.1158/1078-0432.CCR-11- 0127
-
(2011)
Clin Cancer Res
, vol.17
, Issue.14
, pp. 4650-4660
-
-
Jacob, K.1
Quang-Khuong, D.A.2
Jones, D.T.3
Witt, H.4
Lambert, S.5
Albrecht, S.6
Witt, O.7
Vezina, C.8
Shirinian, M.9
Faury, D.10
Garami, M.11
Hauser, P.12
Klekner, A.13
Bognar, L.14
Farmer, J.P.15
Montes, J.L.16
Atkinson, J.17
Hawkins, C.18
Korshunov, A.19
Collins, V.P.20
Pfister, S.M.21
Tabori, U.22
Jabado, N.23
more..
-
26
-
-
0029909798
-
The clinical significance of extracellular matrix in gangliogliomas
-
8957448 10.1097/00005072-199612000-00008 1:STN:280:DyaK2s7hs1elsg%3D%3D
-
Jaffey PB, Mundt AJ, Baunoch DA, Armstrong DL, Hamilton WJ, Zagaja VG, Grossman RG, Wollmann RL (1996) The clinical significance of extracellular matrix in gangliogliomas. J Neuropathol Exp Neurol 55(12):1246-1252
-
(1996)
J Neuropathol Exp Neurol
, vol.55
, Issue.12
, pp. 1246-1252
-
-
Jaffey, P.B.1
Mundt, A.J.2
Baunoch, D.A.3
Armstrong, D.L.4
Hamilton, W.J.5
Zagaja, V.G.6
Grossman, R.G.7
Wollmann, R.L.8
-
27
-
-
55349107544
-
Tandem duplication producing a novel oncogenic BRAF fusion gene defines the majority of pilocytic astrocytomas
-
10.1158/0008-5472.CAN-08-2097 18974108 10.1158/0008-5472.CAN-08-2097 1:CAS:528:DC%2BD1cXhtlSktbfM
-
Jones DT, Kocialkowski S, Liu L, Pearson DM, Backlund LM, Ichimura K, Collins VP (2008) Tandem duplication producing a novel oncogenic BRAF fusion gene defines the majority of pilocytic astrocytomas. Cancer Res 68(21):8673-8677. doi: 10.1158/0008-5472.CAN-08-2097
-
(2008)
Cancer Res
, vol.68
, Issue.21
, pp. 8673-8677
-
-
Jones, D.T.1
Kocialkowski, S.2
Liu, L.3
Pearson, D.M.4
Backlund, L.M.5
Ichimura, K.6
Collins, V.P.7
-
28
-
-
8844252330
-
Mutation analysis of the Ras pathway genes NRAS, HRAS, KRAS and BRAF in glioblastomas
-
10.1007/s00401-004-0929-9 15517309 10.1007/s00401-004-0929-9 1:CAS:528:DC%2BD2cXhtVSitLrK
-
Knobbe CB, Reifenberger J, Reifenberger G (2004) Mutation analysis of the Ras pathway genes NRAS, HRAS, KRAS and BRAF in glioblastomas. Acta Neuropathol 108(6):467-470. doi: 10.1007/s00401-004-0929-9
-
(2004)
Acta Neuropathol
, vol.108
, Issue.6
, pp. 467-470
-
-
Knobbe, C.B.1
Reifenberger, J.2
Reifenberger, G.3
-
29
-
-
84862109270
-
Immunohistochemical detection of the BRAF V600E-mutated protein in papillary thyroid carcinoma
-
10.1097/PAS.0b013e318246b527 22592144 10.1097/PAS.0b013e318246b527
-
Koperek O, Kornauth C, Capper D, Berghoff AS, Asari R, Niederle B, von Deimling A, Birner P, Preusser M (2012) Immunohistochemical detection of the BRAF V600E-mutated protein in papillary thyroid carcinoma. Am J Surg Pathol 36(6):844-850. doi: 10.1097/PAS.0b013e318246b527
-
(2012)
Am J Surg Pathol
, vol.36
, Issue.6
, pp. 844-850
-
-
Koperek, O.1
Kornauth, C.2
Capper, D.3
Berghoff, A.S.4
Asari, R.5
Niederle, B.6
Von Deimling, A.7
Birner, P.8
Preusser, M.9
-
30
-
-
32044455746
-
BRAF mutations are associated with distinctive clinical, pathological and molecular features of colorectal cancer independently of microsatellite instability status
-
10.1186/1476-4598-5-2 16403224 10.1186/1476-4598-5-2
-
Li WQ, Kawakami K, Ruszkiewicz A, Bennett G, Moore J, Iacopetta B (2006) BRAF mutations are associated with distinctive clinical, pathological and molecular features of colorectal cancer independently of microsatellite instability status. Mol Cancer 5:2. doi: 10.1186/1476-4598-5-2
-
(2006)
Mol Cancer
, vol.5
, pp. 2
-
-
Li, W.Q.1
Kawakami, K.2
Ruszkiewicz, A.3
Bennett, G.4
Moore, J.5
Iacopetta, B.6
-
31
-
-
4344660712
-
The ras/mitogen-activated protein kinase pathway inhibitor and likely tumor suppressor proteins, sprouty 1 and sprouty 2 are deregulated in breast cancer
-
10.1158/0008-5472.CAN-04-1207 15342396 10.1158/0008-5472.CAN-04-1207 1:CAS:528:DC%2BD2cXntFClsb4%3D
-
Lo TL, Yusoff P, Fong CW, Guo K, McCaw BJ, Phillips WA, Yang H, Wong ES, Leong HF, Zeng Q, Putti TC, Guy GR (2004) The ras/mitogen-activated protein kinase pathway inhibitor and likely tumor suppressor proteins, sprouty 1 and sprouty 2 are deregulated in breast cancer. Cancer Res 64(17):6127-6136. doi: 10.1158/0008-5472.CAN-04-1207
-
(2004)
Cancer Res
, vol.64
, Issue.17
, pp. 6127-6136
-
-
Lo, T.L.1
Yusoff, P.2
Fong, C.W.3
Guo, K.4
McCaw, B.J.5
Phillips, W.A.6
Yang, H.7
Wong, E.S.8
Leong, H.F.9
Zeng, Q.10
Putti, T.C.11
Guy, G.R.12
-
32
-
-
84978034236
-
Prognostic and clinicopathologic associations of oncogenic BRAF in metastatic melanoma
-
10.1200/JCO.2010.32.4327 21343559 10.1200/JCO.2010.32.4327
-
Long GV, Menzies AM, Nagrial AM, Haydu LE, Hamilton AL, Mann GJ, Hughes TM, Thompson JF, Scolyer RA, Kefford RF (2011) Prognostic and clinicopathologic associations of oncogenic BRAF in metastatic melanoma. J Clin Oncol 29(10):1239-1246. doi: 10.1200/JCO.2010.32.4327
-
(2011)
J Clin Oncol
, vol.29
, Issue.10
, pp. 1239-1246
-
-
Long, G.V.1
Menzies, A.M.2
Nagrial, A.M.3
Haydu, L.E.4
Hamilton, A.L.5
Mann, G.J.6
Hughes, T.M.7
Thompson, J.F.8
Scolyer, R.A.9
Kefford, R.F.10
-
33
-
-
84871619722
-
Immunohistochemistry is highly sensitive and specific for the detection of V600E BRAF mutation in melanoma
-
10.1097/PAS.0b013e31826485c0 23026937 10.1097/PAS.0b013e31826485c0
-
Long GV, Wilmott JS, Capper D, Preusser M, Zhang YE, Thompson JF, Kefford RF, von Deimling A, Scolyer RA (2013) Immunohistochemistry is highly sensitive and specific for the detection of V600E BRAF mutation in melanoma. Am J Surg Pathol 37(1):61-65. doi: 10.1097/PAS.0b013e31826485c0
-
(2013)
Am J Surg Pathol
, vol.37
, Issue.1
, pp. 61-65
-
-
Long, G.V.1
Wilmott, J.S.2
Capper, D.3
Preusser, M.4
Zhang, Y.E.5
Thompson, J.F.6
Kefford, R.F.7
Von Deimling, A.8
Scolyer, R.A.9
-
34
-
-
34547122001
-
The 2007 WHO classification of tumours of the central nervous system
-
10.1007/s00401-007-0243-4 17618441 10.1007/s00401-007-0243-4
-
Louis DN, Ohgaki H, Wiestler OD, Cavenee WK, Burger PC, Jouvet A, Scheithauer BW, Kleihues P (2007) The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol 114(2):97-109. doi: 10.1007/s00401-007-0243-4
-
(2007)
Acta Neuropathol
, vol.114
, Issue.2
, pp. 97-109
-
-
Louis, D.N.1
Ohgaki, H.2
Wiestler, O.D.3
Cavenee, W.K.4
Burger, P.C.5
Jouvet, A.6
Scheithauer, B.W.7
Kleihues, P.8
-
35
-
-
70849116358
-
Profiling critical cancer gene mutations in clinical tumor samples
-
10.1371/journal.pone.0007887 19924296 10.1371/journal.pone.0007887
-
MacConaill LE, Campbell CD, Kehoe SM, Bass AJ, Hatton C, Niu L, Davis M, Yao K, Hanna M, Mondal C, Luongo L, Emery CM, Baker AC, Philips J, Goff DJ, Fiorentino M, Rubin MA, Polyak K, Chan J, Wang Y, Fletcher JA, Santagata S, Corso G, Roviello F, Shivdasani R, Kieran MW, Ligon KL, Stiles CD, Hahn WC, Meyerson ML, Garraway LA (2009) Profiling critical cancer gene mutations in clinical tumor samples. PLoS One 4(11):e7887. doi: 10.1371/journal.pone.0007887
-
(2009)
PLoS One
, vol.4
, Issue.11
, pp. 7887
-
-
MacConaill, L.E.1
Campbell, C.D.2
Kehoe, S.M.3
Bass, A.J.4
Hatton, C.5
Niu, L.6
Davis, M.7
Yao, K.8
Hanna, M.9
Mondal, C.10
Luongo, L.11
Emery, C.M.12
Baker, A.C.13
Philips, J.14
Goff, D.J.15
Fiorentino, M.16
Rubin, M.A.17
Polyak, K.18
Chan, J.19
Wang, Y.20
Fletcher, J.A.21
Santagata, S.22
Corso, G.23
Roviello, F.24
Shivdasani, R.25
Kieran, M.W.26
Ligon, K.L.27
Stiles, C.D.28
Hahn, W.C.29
Meyerson, M.L.30
Garraway, L.A.31
more..
-
36
-
-
43049124130
-
BRAF gene duplication constitutes a mechanism of MAPK pathway activation in low-grade astrocytomas
-
10.1172/JCI33656 18398503 10.1172/JCI33656 1:CAS:528:DC%2BD1cXlsF2ntLY%3D
-
Pfister S, Janzarik WG, Remke M, Ernst A, Werft W, Becker N, Toedt G, Wittmann A, Kratz C, Olbrich H, Ahmadi R, Thieme B, Joos S, Radlwimmer B, Kulozik A, Pietsch T, Herold-Mende C, Gnekow A, Reifenberger G, Korshunov A, Scheurlen W, Omran H, Lichter P (2008) BRAF gene duplication constitutes a mechanism of MAPK pathway activation in low-grade astrocytomas. J Clin Invest 118(5):1739-1749. doi: 10.1172/JCI33656
-
(2008)
J Clin Invest
, vol.118
, Issue.5
, pp. 1739-1749
-
-
Pfister, S.1
Janzarik, W.G.2
Remke, M.3
Ernst, A.4
Werft, W.5
Becker, N.6
Toedt, G.7
Wittmann, A.8
Kratz, C.9
Olbrich, H.10
Ahmadi, R.11
Thieme, B.12
Joos, S.13
Radlwimmer, B.14
Kulozik, A.15
Pietsch, T.16
Herold-Mende, C.17
Gnekow, A.18
Reifenberger, G.19
Korshunov, A.20
Scheurlen, W.21
Omran, H.22
Lichter, P.23
more..
-
37
-
-
79957880389
-
BRAF activation induces transformation and then senescence in human neural stem cells: A pilocytic astrocytoma model
-
10.1158/1078-0432.CCR-10-3349 21636552 10.1158/1078-0432.CCR-10-3349 1:CAS:528:DC%2BC3MXmvFCqurs%3D
-
Raabe EH, Lim KS, Kim JM, Meeker A, Mao XG, Nikkhah G, Maciaczyk J, Kahlert U, Jain D, Bar E, Cohen KJ, Eberhart CG (2011) BRAF activation induces transformation and then senescence in human neural stem cells: a pilocytic astrocytoma model. Clin Cancer Res 17(11):3590-3599. doi: 10.1158/1078-0432.CCR- 10-3349
-
(2011)
Clin Cancer Res
, vol.17
, Issue.11
, pp. 3590-3599
-
-
Raabe, E.H.1
Lim, K.S.2
Kim, J.M.3
Meeker, A.4
Mao, X.G.5
Nikkhah, G.6
MacIaczyk, J.7
Kahlert, U.8
Jain, D.9
Bar, E.10
Cohen, K.J.11
Eberhart, C.G.12
-
38
-
-
0022518090
-
Comparative histological, histochemical, immunohistochemical and biochemical studies on oestrogen receptors, lectin receptors, and Barr bodies in human breast cancer
-
2424168 10.1007/BF00708323 1:STN:280:DyaL283jslSrsg%3D%3D
-
Remmele W, Hildebrand U, Hienz HA, Klein PJ, Vierbuchen M, Behnken LJ, Heicke B, Scheidt E (1986) Comparative histological, histochemical, immunohistochemical and biochemical studies on oestrogen receptors, lectin receptors, and Barr bodies in human breast cancer. Virchows Arch A Pathol Anat Histopathol 409(2):127-147
-
(1986)
Virchows Arch A Pathol Anat Histopathol
, vol.409
, Issue.2
, pp. 127-147
-
-
Remmele, W.1
Hildebrand, U.2
Hienz, H.A.3
Klein, P.J.4
Vierbuchen, M.5
Behnken, L.J.6
Heicke, B.7
Scheidt, E.8
-
39
-
-
84876098212
-
Brainstem Ganglioglioma Successfully Treated with Vemurafenib
-
10.1200/JCO.2012.44.1568 23358987
-
Rush S, Foreman N, Liu A (2013) Brainstem Ganglioglioma Successfully Treated With Vemurafenib. J Clin Oncol. doi: 10.1200/JCO.2012.44.1568
-
(2013)
J Clin Oncol
-
-
Rush, S.1
Foreman, N.2
Liu, A.3
-
40
-
-
84866624067
-
BRAFV600E mutant protein is expressed in cells of variable maturation in Langerhans cell histiocytosis
-
10.1182/blood-2012-06-429597 22859608 10.1182/blood-2012-06-429597 1:CAS:528:DC%2BC38XhsVKiu7rJ
-
Sahm F, Capper D, Preusser M, Meyer J, Stenzinger A, Lasitschka F, Berghoff AS, Habel A, Schneider M, Kulozik A, Anagnostopoulos I, Mullauer L, Mechtersheimer G, von Deimling A (2012) BRAFV600E mutant protein is expressed in cells of variable maturation in Langerhans cell histiocytosis. Blood 120(12):e28-e34. doi: 10.1182/blood-2012-06-429597
-
(2012)
Blood
, vol.120
, Issue.12
-
-
Sahm, F.1
Capper, D.2
Preusser, M.3
Meyer, J.4
Stenzinger, A.5
Lasitschka, F.6
Berghoff, A.S.7
Habel, A.8
Schneider, M.9
Kulozik, A.10
Anagnostopoulos, I.11
Mullauer, L.12
Mechtersheimer, G.13
Von Deimling, A.14
-
41
-
-
76549137130
-
Oncogenic BRAF mutation with CDKN2A inactivation is characteristic of a subset of pediatric malignant astrocytomas
-
10.1158/0008-5472.CAN-09-1851 20068183 10.1158/0008-5472.CAN-09-1851 1:CAS:528:DC%2BC3cXltlWrsg%3D%3D
-
Schiffman JD, Hodgson JG, VandenBerg SR, Flaherty P, Polley MY, Yu M, Fisher PG, Rowitch DH, Ford JM, Berger MS, Ji H, Gutmann DH, James CD (2010) Oncogenic BRAF mutation with CDKN2A inactivation is characteristic of a subset of pediatric malignant astrocytomas. Cancer Res 70(2):512-519. doi: 10.1158/0008-5472.CAN-09-1851
-
(2010)
Cancer Res
, vol.70
, Issue.2
, pp. 512-519
-
-
Schiffman, J.D.1
Hodgson, J.G.2
Vandenberg, S.R.3
Flaherty, P.4
Polley, M.Y.5
Yu, M.6
Fisher, P.G.7
Rowitch, D.H.8
Ford, J.M.9
Berger, M.S.10
Ji, H.11
Gutmann, D.H.12
James, C.D.13
-
42
-
-
79954441895
-
Analysis of BRAF V600E mutation in 1,320 nervous system tumors reveals high mutation frequencies in pleomorphic xanthoastrocytoma, ganglioglioma and extra-cerebellar pilocytic astrocytoma
-
10.1007/s00401-011-0802-6 21274720 10.1007/s00401-011-0802-6 1:CAS:528:DC%2BC3MXhvVyrsrk%3D
-
Schindler G, Capper D, Meyer J, Janzarik W, Omran H, Herold-Mende C, Schmieder K, Wesseling P, Mawrin C, Hasselblatt M, Louis DN, Korshunov A, Pfister S, Hartmann C, Paulus W, Reifenberger G, von Deimling A (2011) Analysis of BRAF V600E mutation in 1,320 nervous system tumors reveals high mutation frequencies in pleomorphic xanthoastrocytoma, ganglioglioma and extra-cerebellar pilocytic astrocytoma. Acta Neuropathol 121(3):397-405. doi: 10.1007/s00401-011-0802-6
-
(2011)
Acta Neuropathol
, vol.121
, Issue.3
, pp. 397-405
-
-
Schindler, G.1
Capper, D.2
Meyer, J.3
Janzarik, W.4
Omran, H.5
Herold-Mende, C.6
Schmieder, K.7
Wesseling, P.8
Mawrin, C.9
Hasselblatt, M.10
Louis, D.N.11
Korshunov, A.12
Pfister, S.13
Hartmann, C.14
Paulus, W.15
Reifenberger, G.16
Von Deimling, A.17
-
43
-
-
84867743674
-
Pediatric primary anaplastic ganglioglioma: A case report and review of the literature
-
10.1159/000340067 22922381 10.1159/000340067
-
Scoccianti S, Giordano F, Agresti B, Detti B, Cipressi S, Franceschini D, Greto D, Mussa F, Sardi I, Buccoliero A, Arico M, Genitori L, Biti G (2012) Pediatric primary anaplastic ganglioglioma: a case report and review of the literature. Pediatr Neurosurg 48(1):35-41. doi: 10.1159/000340067
-
(2012)
Pediatr Neurosurg
, vol.48
, Issue.1
, pp. 35-41
-
-
Scoccianti, S.1
Giordano, F.2
Agresti, B.3
Detti, B.4
Cipressi, S.5
Franceschini, D.6
Greto, D.7
Mussa, F.8
Sardi, I.9
Buccoliero, A.10
Arico, M.11
Genitori, L.12
Biti, G.13
-
44
-
-
84865001178
-
Detection of BRAF V600E mutations in skin metastases of malignant melanoma by monoclonal antibody VE1
-
10.1016/j.jaad.2012.03.022 22890732 10.1016/j.jaad.2012.03.022 1:CAS:528:DC%2BC38XhtF2itLvO
-
Skorokhod A, Capper D, von Deimling A, Enk A, Helmbold P (2012) Detection of BRAF V600E mutations in skin metastases of malignant melanoma by monoclonal antibody VE1. J Am Acad Dermatol 67(3):488-491. doi: 10.1016/j.jaad.2012.03.022
-
(2012)
J Am Acad Dermatol
, vol.67
, Issue.3
, pp. 488-491
-
-
Skorokhod, A.1
Capper, D.2
Von Deimling, A.3
Enk, A.4
Helmbold, P.5
-
45
-
-
4143139997
-
SPRY2 is an inhibitor of the ras/extracellular signal-regulated kinase pathway in melanocytes and melanoma cells with wild-type BRAF but not with the V599E mutant
-
10.1158/0008-5472.CAN-04-1669 15313890 10.1158/0008-5472.CAN-04-1669 1:CAS:528:DC%2BD2cXmslaltbs%3D
-
Tsavachidou D, Coleman ML, Athanasiadis G, Li S, Licht JD, Olson MF, Weber BL (2004) SPRY2 is an inhibitor of the ras/extracellular signal-regulated kinase pathway in melanocytes and melanoma cells with wild-type BRAF but not with the V599E mutant. Cancer Res 64(16):5556-5559. doi: 10.1158/0008-5472.CAN- 04-1669
-
(2004)
Cancer Res
, vol.64
, Issue.16
, pp. 5556-5559
-
-
Tsavachidou, D.1
Coleman, M.L.2
Athanasiadis, G.3
Li, S.4
Licht, J.D.5
Olson, M.F.6
Weber, B.L.7
-
46
-
-
1842331460
-
Evidence for clonal origin of neoplastic neuronal and glial cells in gangliogliomas
-
9250169 1:CAS:528:DyaK2sXls1WmsL8%3D
-
Zhu JJ, Leon SP, Folkerth RD, Guo SZ, Wu JK, Black PM (1997) Evidence for clonal origin of neoplastic neuronal and glial cells in gangliogliomas. Am J Pathol 151(2):565-571
-
(1997)
Am J Pathol
, vol.151
, Issue.2
, pp. 565-571
-
-
Zhu, J.J.1
Leon, S.P.2
Folkerth, R.D.3
Guo, S.Z.4
Wu, J.K.5
Black, P.M.6
|