Nicotinamide attenuates the injury-induced decrease of hippocalcin in ischemic brain injury

Neuroscience Letters

Volumn 545, Issue , 2013, Pages 6-10

  Koh, Phil Ok ^a  

^a Gyeongsang National University   (South Korea)

Author keywords

Hippocalcin; Neuroprotection; Nicotinamide

Indexed keywords

GLUTAMIC ACID; HIPPOCALCIN; NICOTINAMIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; BRAIN TISSUE; CONTROLLED STUDY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NERVE CELL NECROSIS; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEOMICS; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SINGLE DRUG DOSE; WESTERN BLOTTING;

ANIMALS; DOWN-REGULATION; HIPPOCALCIN; INFARCTION, MIDDLE CEREBRAL ARTERY; MALE; NEUROPROTECTIVE AGENTS; NIACINAMIDE; RATS; RATS, SPRAGUE-DAWLEY; TREATMENT OUTCOME;

EID: 84878607219     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2013.04.010     Document Type: Article

References (27)

1. Carafoli E. Intracellular calcium homeostasis. Ann. Rev. Biochem. 1987, 56:395-433.
2. Crowley C.L., Payne C.M., Bernstein H., Bernstein C., Roe D. The NAD+ precursors, nicotinic acid and nicotinamide protect cells against apoptosis induced by a multiple stress inducer, deoxycholate. Cell Death Differ. 2000, 7:314-326.
3. Hayashi T., Abe K. Ischemic neuronal cell death and organellae damage. Neurol. Res. 2004, 26:827-834.
4. Hoane M.R., Tan A.A., Pierce J.L., Anderson G.D., Smith D.C. Nicotinamide treatment reduces behavioural impairments and provides cortical protection after fluid percussion injury in the rat. J. Neurotrauma 2006, 10:1535-1548.
5. Hoane M.R., Kaplan S.A., Ellis A.L. The effects of nicotinamide on apoptosis and blood-brain barrier breakdown following traumatic brain injury. Brain Res. 2006, 1125:185-193.
6. Hoane M.R., Gilbert D.R., Holland M.A., Pierce J.L. Nicotinamide reduces acute cortical neuronal death and edema in the traumatically injured brain. Neurosci. Lett. 2006, 408:35-39.
7. Holland M.A., Tan A.A., Smith D.C., Hoane M.R. Nicotinamide treatment provides acute neuroprotection and GFAP regulation following fluid percussion injury. J. Neurotrauma 2008, 25:140-152.
8. Katsura K., Kristián T., Siesjo B.K. Energy metabolism, ion homeostasis, and cell damage in the brain. Biochem. Soc. Trans. 1994, 22:991-996.
9. Kennedy M.B. Regulation of neuronal function by calcium. Trends Neurosci. 1989, 12:417-420.
10. Klaidman L., Morales M., Kem S., Yang J., Chang M.L., Adams J.D. Nicotinamide offers multiple protective mechanisms in stroke as a precursor for NAD+, as a PARP inhibitor and by partial restoration of mitochondrial function. Pharmacology 2003, 69:150-157.
11. Koh P.O. Ischemic injury decreases parvalbumin expression in a middle cerebral artery occlusion animal model and glutamate-exposed HT22 cells. Neurosci. Lett. 2012, 512:17-21.
12. Koh P.O. Focal cerebral ischemia reduces protein phosphatase 2A subunit B expression in brain tissue and HT22 cell. Lab. Anim. Res. 2011, 27:73-76.
13. Koh P.O. Nicotinamide restores the reduction of parvalbumin in cerebral ischemic injury. J. Vet. Med. Sci. 2013, 75:225-229.
14. Korhonen L., Hansson I., Kukkonen J.P., Brannvall K., Kobayashi M., Takamatsu K., Lindholm D. Hippocalcin protects against caspase-12-induced and age-dependent neuronal degeneration. Mol. Cell. Neurosci. 2005, 28:85-95.
15. Kristian T., Siesjo B.K. Calcium in ischemic cell death. Stroke 1998, 29:705-718.
16. Li F., Chong Z.Z., Maiese K. Navigating novel mechanisms of cellular plasticity with the NAD+ precursor and nutrient nicotinamide. Front. Biosci. 2004, 9:2500-2520.
17. Lindholm D., Mercer E.A., Yu L.Y., Chen Y., Kukkonen J., Korhonen L., Arumäe U. Neuronal apoptosis inhibitory protein: structural requirements for hippocalcin binding and effects on survival of NGF-dependent sympathetic neurons. Biochim. Biophys. Acta 2002, 1600:138-147.
18. Longa E.Z., Weinstein P.R., Carlson S., Cummins R. Reversible middle cerebral artery occlusion without craniectomy in rats. Stroke 1989, 20:84-91.
19. Maher P., Davis J.B. The role of monoamine metabolism in oxidative glutamate toxicity. J. Neurosci. 1996, 16:6394-6401.
20. Mercer E.A., Korhonen L., Skoglosa Y., Olsson P.A., Kukkonen J.P., Lindholm D. NAIP interacts with hippocalcin and protects neurons against calcium-induced cell death through caspase-3-dependent and -independent pathways. EMBO J. 2000, 19:3597-3607.
21. Mokudai T., Ayoub I.A., Sakakibara Y., Lee E.J., Ogilvy C.S., Maynard K.I. Delayed treatment with nicotinamide (Vitamin B(3)) improves neurological outcome and reduces infarct volume after transient focal cerebral ischemia in Wistar rats. Stroke 2000, 31:1679-1685.
22. Orrenius S., Nicotera P. The calcium ion and cell death. J. Neural. Transm. Suppl. 1994, 43:1-11.
23. Saitoh S., Takamatsu K., Kobayashi M., Noguchi T. Distribution of hippocalcin mRNA and immunoreactivity in rat brain. Neurosci. Lett. 1993, 157:107-110.
24. Slomka M., Zieminska E., Salinska E., Lazarewicz J.W. Neuroprotective effects of nicotinamide and 1-methylnicotinamide in acute excitotoxicity in vitro. Folia Neuropathol. 2008, 46:69-80.
25. Starkov A.A., Chinopoulos C., Fiskum G. Mitochondrial calcium and oxidative stress as mediators of ischemic brain injury. Cell Calcium 2004, 36:257-264.
26. Sung J.H., Kim M.O., Koh P.O. Nicotinamide prevents the down-regulation of MEK/ERK/p90RSK signaling cascade in brain ischemic injury. J. Vet. Med. Sci. 2012, 74:35-41.
27. Yang J., Klaidman L.K., Chang M.L., Kem S., Sugawara T., Chan P. Nicotinamide therapy protects against both necrosis and apoptosis in a stroke model. Pharmacol. Biochem. Behav. 2002, 73:901-910.