Evaluation of antinociceptive activity of Ajuga bracteosa wall ex benth

International Journal of Green Pharmacy

Volumn 7, Issue 1, 2013, Pages 73-76

  Khatri, Raghunath Singh ^a   Ahmad, Mumtaz ^a   Pal, Gagandeep ^a   Ashwlayan, Vrish Dhwaj ^b  

^a Dev Bhoomi Uttarakhand University   (India)

^b SHOBHIT UNIVERSITY   (India)

Author keywords

Anti nociceptive; codeine; formalin; tail flick

Indexed keywords

AJUGA BRACTEOSA EXTRACT; ANTINOCICEPTIVE AGENT; CODEINE; PLANT EXTRACT; UNCLASSIFIED DRUG;

AJUGA; AJUGA BRACTEOSA; ANALGESIA; ANALGESIC ACTIVITY; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; LICKING; MOUSE; NONHUMAN; PAIN; PAIN ASSESSMENT; REACTION TIME; TAIL FLICK TEST;

EID: 84878599085     PISSN: 09738258     EISSN: 19984103     Source Type: Journal    
DOI: 10.4103/0973-8258.111631     Document Type: Article

References (29)

1. Sosa S, Balicet MJ, Arvigo R, Esposito RG, Pizza C, Altinier GA. Screening of the topical anti-inflammatory activity of some central American plants. J Ethanopharmacol 2002;8:211-5. (Pubitemid 34628504)
2. Pilotto A, Franceschi M, Leandro G, Paris F, Niro V, Longo MG, et al. The risk of upper gastrointestinal bleeding in elderly users of aspirin and other non-steroidal anti-inflammatory drugs: The role of gastroprotective drugs. Aging Clin Exp Res 2003;15:494-9. (Pubitemid 38180788)
3. David J, Douglas J. Acute post-operative pain. In: Healy TE, Knight PR, editors. Wylie and Churchil-Davidson's a practice of Anaesthesia, 7 th ed. London: Hodder Arnold 2003. p. 1213-20.
4. Riaz N, Malik A, Aziz-ur-Rehman, Nawaz, SA, Muhammad P, and Choudhary MI. Cholinesterase-inhibiting withanolides from Ajuga bracteosa. Chem Biodivers 2004;1:1289-95.
5. Riaz N, Nawaz SA, Mukhtar N, Malik A, Afza N, Ali S, et al. Isolation and enzyme-inhibition studies of the chemical constituents from Ajuga bracteosa. Chem Biodivers 2007;4:72-83. (Pubitemid 46195866)
6. Choudhary MI, Nawaz SA, Haq ZU, Lodhi MA, Ghayur MN, Jalil S, et al. Withanolides, a new class of natural cholinesterase inhibitors with calcium antagonistic properties. Biochem Biophys Res Commun 2005;334:276-87. (Pubitemid 40978536)
7. Ghufran MA, Qureshi RA, Batool A, Kondratyuk TP, Guilford JM, Marler LE, et al. Evaluation of selected indigenous medicinal plants from the western Himalayas for cytotoxicity and as potential cancer chemopreventive agents. Pharmaceutical Biol 2009;47:533-8.
8. Chandel S, Bagai U. Antiplasmodial activity of Ajuga bracteosa against Plasmodium berghei infected BALB/c mice. Indian J Med Res 2010;131:440-4.
9. Gautam R, Jachak SM, Saklani A. Anti-inflammatory effect of Ajuga bracteosa Wall. Ex Benth. mediated through cyclooxygenase (COX) inhibition. J Ethnopharmacol 2011;133:928-30.
10. Pal A, Panwar RS. A study on Ajuga bracteosa Wall, ex Benth for analgesic activity. Int J Biol Med Res 2012;1:12-4.
11. Kaithwas G, Gautum R, Jachak SM, Saklani A. Antiarthritic effects of Ajuga bracteosa Wall ex Benth. in acute and chronic models of arthritis in albino rats. Asian Pac J Trop Biomed 2012;2:185-8.
12. Patel DG, Gulati OD, Gokhale SD. Positive inotropic action of an alkaloidal fraction from Ajuga bracteosa Well ex Benth. Indian J Physiol Pharmcol 1962;6:224-30.
13. Singh R, Patil SM, Pal G, Ahmad M. Evaluation of in vivo and in vitro anti-inflammatory activity of Ajuga bracteosa Wall ex Benth. Asian Pac J Trop Dis 2012;S404-7.
14. Mbagwu HO, Anene RA, Adeyemi OO. Analgesic, antipyretic and antiinflammatory properties of Mezoneuron benthamianum Baill (Caesalpiniaceae). Nig Q J Hosp Med 2007;17:35-41.
15. Prempeh ABA, Mensah AJ. Analgesic activity of crude aqueous extract of the root bark of Zanthoxylum Xanthoxyloides. Ghana Med J 2008;42:79-84.
16. Pradeep K, Krishna V, Venkatesh, Girish Kumar K, Santosh Kumar SR, Joy H Hoskeri, et al. Antinoceceptive activity of Delonix elata leaf extract. Asian Pac J Trop Biomed 2012;S229-31.
17. Okokon JE, Nwafor PA. Antiinflammatory, analgesic and antipyretic activities of ethanolic root extract of Croton zambesicus. Pak J Pharm Sci 2010;23:383-90.
18. Nwafor PA, Jacks TW, Ekanem AU. Analgesic and anti-inflammatory effects of methanolic extract of Pausinystalia mecroceras stem bark in rodents. J Pharmacol 2007;3:86-90. (Pubitemid 46730180)
19. Dubuission D and Deniss SG. The formalin test: A quantitative study of the analgesic effect of morphine meperidine and brain stem stimulation in rats and cats. Pain 1977 4;161-74.
20. Wong CH, Dey P, Yarmush J, Wu WH, Zbuzek VK. Nifedipine-induced analgesia after epidural injections in rats. Anesth Analg 1994;79:303-6. (Pubitemid 24240869)
21. Richardson JD, Aanonsen L, Hargreaves KM. Antihyperalgesic effects of spinal cannabinoids. Eur J Pharmacol 1998;345:145-53. (Pubitemid 28212345)
22. Chapman CR, Casey KL, Dubner R, Foley KM, Gracely RH, Reading AE. Pain measurement: An overview. Pain 1985;22:1-31. (Pubitemid 15037578)
23. Grumbach L, The production of analgesic activity in man by animal testing. In: Knighton RS, Dumke PR, editors. Pain. Boston: Little Brown and Co; 1966. p. 163-82.
24. Dhawan BN, Cesselin F, Raghubir R, Reisine T, Bradley PB, Portoghese PS, et al. International Union of Pharmacology. XII. Classification of opioid receptors. Pharmacol Rev 1996;48:567-92. (Pubitemid 27023821)
25. Lipman AG, Jackson RC. Opioids. In: Warfield C, Bajwa Z, editors. Principles and Practice of Pain Medicine. New York: McGraw-Hill; 2004. p. 585-8.
26. O'Brien CP. Drug addiction and drug abuse. In: Brunton LL, Lazo JS, Parker KL, editors. Goodman and Gilman's the pharmacological basis of therapeutics. New York: McGraw-Hill; 2006. p. 617.
27. Whittle BA. The use of changes in capillary permeability in rats to distinguish between narcotic and non-narcotic analgesics. Br J Pharmacol Chemother 1964;22:246-53.
28. Chau TT. Analgesic testing in animal models, Pharmacological methods in the control of inflammation. New York: Liss; 1989. p. 195-212.
29. Hunskaar S, Hole K. The formalin test in mice, dissociation between inflammatory pain. Pain 1987;30:103-14. (Pubitemid 17094194)