The efficiency and stability of bubble formation by acoustic vaporization of submicron perfluorocarbon droplets

Ultrasonics

Volumn 53, Issue 7, 2013, Pages 1368-1376

  Reznik, Nikita ^a   Shpak, Oleksandr ^b   Gelderblom, Erik C ^b   Williams, Ross ^c   De Jong, Nico ^b,d   Versluis, Michel ^b   Burns, Peter N ^a,c  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TWENTE   (Netherlands)

^c Canada   (Canada)

^d ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

Ultrasound contrast agents Perfluorocarbon droplets Droplet vaporization High speed imaging Microbubbles

Indexed keywords

BUBBLE COALESCENCE; COATING MATERIAL; LIQUID DROPLETS; OPTICAL IMAGING; PERFLUOROCARBONS; ULTRA HIGH SPEED; ULTRASOUND CONTRAST AGENT; ULTRASOUND EXCITATION;

BUBBLES (IN FLUIDS); COALESCENCE; DROPS; MEDICAL IMAGING; ULTRASONICS; VAPORIZATION;

VAPORS;

CONTRAST MEDIUM; FLUOROCARBON; ORGANIC COMPOUND; PERFLUOROPENTANE; ZONYL;

ACOUSTICS; ARTICLE; CHEMISTRY; EQUIPMENT DESIGN; HUMAN; MICROBUBBLE; TRANSDUCER; VOLATILIZATION;

ACOUSTICS; CONTRAST MEDIA; EQUIPMENT DESIGN; FLUOROCARBONS; HUMANS; MICROBUBBLES; ORGANIC CHEMICALS; TRANSDUCERS; VOLATILIZATION;

MLCS; MLOWN;

EID: 84878540855     PISSN: 0041624X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ultras.2013.04.005     Document Type: Conference Paper

References (44)

1. T.O. Matsunaga, P.S. Sheeran, S. Luois, J.E. Streeter, L.B. Mullin, B. Banerjee, and P.A. Dayton Phase-change nanoparticles using highly volatile per-fluorocarbons: toward a platform for extravascular ultrasound imaging Theranostics 2 12 2012 1185 1198
2. O.D. Kripfgans, J.B. Fowlkes, D.L. Miller, O.P. Eldevik, and P.L. Carson Acoustic droplet vaporization for therapeutic and diagnostic applications Ultrasound Med. Biol. 26 7 2000 1177 1189
3. P.S. Sheeran, and P.A. Dayton Phase-change contrast agents for imaging and therapy Curr. Pharm. Des. 18 15 2012 2152 2165
4. M. Zhang, M.L. Fabiilli, K.J. Haworth, J.B. Fowlkes, O.D. Kripfgans, W.W. Roberts, K.A. Ives, and P.L. Carson Initial investigation of acoustic droplet vaporization for occlusion in canine kidney. Ultrasound Med. Biol. 36 10 2010 1691 1703
5. C.M. Carneal, O.D. Kripfgans, J. Krucker, P.L. Carson, and J.B. Fowlkes A tissue-mimicking ultrasound test object using droplet vaporization to create point targets IEEE Trans. Ultrason. Ferr. 58 9 2011 2013 2025
6. P. Zhang, and T. Porter An in vitro study of a phase-shift nanoemulsion: a potential nucleation agent for bubble-enhanced HIFU tumor ablation Ultrasound Med. Biol. 36 11 2010 1856 1866
7. K.C. Schad, and K. Hynynen In vitro characterization of perfluorocarbon droplets for focused ultrasound therapy Phys. Med. Biol. 55 17 2010 4933 4947
8. K.-I. Kawabata, N. Sugita, H. Yoshikawa, T. Azuma, and S. Umemura Nanoparticles with multiple perfluorocarbons for controllable ultrasonically induced phase shifting Jpn. J. Appl. Phys. 44 6 2005 4548 4552
9. M. Zhang, M.L. Fabiilli, K.J. Haworth, F. Padilla, S.D. Swanson, O.D. Kripfgans, P.L. Carson, and J.B. Fowlkes Acoustic droplet vaporization for enhancement of thermal ablation by high intensity focused ultrasound Acad Radiol 18 9 2011 1123 1132
10. M.L. Fabiilli, K.J. Haworth, I.E. Sebastian, O.D. Kripfgans, P.L. Carson, and J.B. Fowlkes Delivery of chlorambucil using an acoustically-triggered perfluoropentane emulsion Ultrasound Med. Biol. 36 8 2010 1364 1375
11. M.L. Fabiilli, J.A. Lee, O.D. Kripfgans, P.L. Carson, and J.B. Fowlkes Delivery of water-soluble drugs using acoustically triggered perfluorocarbon double emulsions Pharm. Res. 27 12 Dec. 2010 2753 2765
12. N.Y. Rapoport, Z. Gao, and A. Kennedy Multifunctional nanoparticles for combining ultrasonic tumor imaging and targeted chemotherapy J. Natl. Cancer Inst. 99 14 Jul. 2007 1095 1106
13. O. Couture, A. Urban, A. Bretagne, L. Martinez, M. Tanter, and P. Tabeling In vivo targeted delivery of large payloads with an ultrasound clinical scanner Med. Phys. 39 8 2012 5229 5237
14. N. Reznik, R. Williams, and P.N. Burns Investigation of vaporized submicron perfluorocarbon droplets as an ultrasound contrast agent Ultrasound Med. Biol. 37 8 2011 1271 1279
15. P.S. Sheeran, V.P. Wong, S. Luois, R.J. McFarland, W.D. Ross, S. Feingold, T.O. Matsunaga, and P.A. Dayton Decafluorobutane as a phase-change contrast agent for low-energy extravascular ultrasonic imaging Ultrasound Med. Biol. 37 9 2011 1518 1530
16. H. Maeda, J. Wu, T. Sawa, Y. Matsumura, and K. Hori Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review J. Control Release 65 1 2000 271 284
17. R.F. Mattrey, F. Scheible, and B.B. Gosink Perfluoroctylbromide: a liver/spleen-specific and tumor-imaging ultrasound contrast material Radiology 1982 20
18. P.N. Burns, and S.R. Wilson Focal liver masses: enhancement patterns on contrast-enhanced images-concordance of US scans with CT scans and MR images Radiology 242 1 2007 162 174
19. J.M. Hudson, R. Williams, B. Lloyd, M. Atri, T.K. Kim, G. Bjarnason, and P.N. Burns Improved flow measurement using microbubble contrast agents and disruption-replenishment: clinical application to tumour monitoring Ultrasound Med. Biol. 37 8 2011 1210 1221
20. O.D. Kripfgans, M.L. Fabiilli, P.L. Carson, and J.B. Fowlkes On the acoustic vaporization of micrometer-sized droplets J. Acoust. Soc. Am. 116 1 2004 272 281
21. Z.Z. Wong, O.D. Kripfgans, A. Qamar, J.B. Fowlkes, and J.L. Bull Bubble evolution in acoustic droplet vaporization at physiological temperature via ultra-high speed imaging Soft Matter 7 8 2011 4009
22. K.J. Haworth, O.D, Kripfgans, Initial growth and coalescence of acoustically vaporized perfluorocarbon microdroplets, in: Presented at the IEEE Ultrasonics Symposium, 2008, pp. 623-626.
23. C.C. Church Spontaneous homogeneous nucleation, inertial cavitation and the safety of diagnostic ultrasound Ultrasound Med. Biol. 28 10 2002 1349 1364
24. E. Barber, and G. Cady Vapor pressures of perfluoropentanes J. Phys. Chem.-US 60 4 1956 504 505
25. L.B. Allen, and J.L. Kassner The nucleation of water vapor in the absence of particulate matter and ions J. Colloid Interf. Sci. 30 1 1969 81 93
26. N. Reznik, M. Seo, R. Williams, E. Bolewska-Pedyczak, M. Lee, N. Matsuura, J. Gariepy, F.S. Foster, and P.N. Burns Optical studies of vaporization and stability of fluorescently labelled perfluorocarbon droplets Phys. Med. Biol. 57 21 2012 7205 7217
27. E. Stride The influence of surface adsorption on microbubble dynamics Philos. Trans. Roy. Soc. A 366 1873 2008 2103
28. A. Atchley The Blake threshold of a cavitation nucleus having a radius-dependent surface tension J. Acoust. Soc. Am. 85 1 1989 152 157
29. N. Matsuura, R. Williams, I. Gorelikov, J. Chaudhuri, N. Reznik, J. Rowlands, K. Hynynen, F.S. Foster, P.N. Burns, Nanoparticle-loaded perfluorocarbon droplets for imaging and therapy, in: Presented at the IEEE Ultrasonics Symposium, 2009, pp. 5-8.
30. R. Williams, C. Wright, E. Cherin, N. Reznik, M. Lee, I. Gorelikov, F.S. Foster, N. Matsuura, and P.N. Burns Characterization of submicron phase-change perfluorocarbon droplets for extravascular ultrasound imaging of cancer Ultrasound Med. Biol. 39 3 2013 475 489
31. C.T. Chin, C. Lancée, J.M.G. Borsboom, F. Mastik, M.E. Frijlink, N. de Jong, M. Versluis, and D. Lohse Brandaris 128: A digital 25 million frames per second camera with 128 highly sensitive frames Rev. Sci. Instrum. 74 12 2003 5026
32. S.M. van der Meer, B. Dollet, M.M. Voormolen, C.T. Chin, A. Bouakaz, N. de Jong, M. Versluis, and D. Lohse Microbubble spectroscopy of ultrasound contrast agents J. Acoust. Soc. Am. 121 1 2007 648 656
33. A.L. Klibanov, P.T. Rasche, M.S. Hughes, J.K. Wojdyla, K.P. Galen, J.H. Wible, and G.H. Brandenburger Detection of individual microbubbles of ultrasound contrast agents: imaging of free-floating and targeted bubbles Invest Radiol 39 3 2004 187 195
34. T. Giesecke, and K. Hynynen Ultrasound-mediated cavitation thresholds of liquid perfluorocarbon droplets in vitro Ultrasound Med. Biol. 29 9 2003 1359 1365
35. K. Sarkar, A. Katiyar, and P. Jain Growth and dissolution of an encapsulated contrast microbubble: effects of encapsulation permeability Ultrasound Med. Biol. 35 8 2009 1385 1396
36. A. Kabalnov, D. Klein, T. Pelura, E. Schutt, and J. Weers Dissolution of multicomponent microbubbles in the bloodstream: 1. Theory Ultrasound Med. Biol. 24 5 1998 739 749
37. K.-I. Kawabata, R. Asami, T. Azuma, S. Umemura, Effect of low intensity CW ultrasound on acoustic responses of microbubbles generated from phase change nano droplet, in: Presented at the IEEE Ultrasonics Symposium, 2010, pp. 1940-1943.
38. C.-H. Wang, S.-T. Kang, Y.-H. Lee, Y.-L. Luo, Y.-F. Huang, and C.-K. Yeh Aptamer-conjugated and drug-loaded acoustic droplets for ultrasound theranosis Biomaterials 33 6 2012 1939 1947
39. M.L.J. Overvelde, V. Garbin, J. Sijl, B. Dollet, N. de Jong, D. Lohse, and M. Versluis Nonlinear shell behavior of phospholipid-coated microbubbles Ultrasound Med. Biol. 36 12 2010 2080 2092
40. D.E. Yount On the evolution, generation, and regeneration of gas cavitation nuclei J. Acoust. Soc. Am. 71 6 1982 1473 1481
41. D.F. Evans, and H. Wennerström The Colloidal Domain: Where Physics, Chemistry and Biology Meet 1999 Wiley-VCH New York
42. P.S. Sheeran, S. Luois, P.A. Dayton, and T.O. Matsunaga Formulation and acoustic studies of a new phase-shift agent for diagnostic and therapeutic ultrasound Langmuir 27 17 2011 10412 10420
43. M.L. Fabiilli, K.J. Haworth, N.H. Fakhri, O.D. Kripfgans, P.L. Carson, and J.B. Fowlkes The role of inertial cavitation in acoustic droplet vaporization IEEE Trans. Ultrason. Ferr. 56 5 2009 1006 1017
44. N.Y. Rapoport, D.A. Christensen, A.M. Kennedy, and K.-H. Nam Cavitation properties of block copolymer stabilized phase-shift nanoemulsions used as drug carriers Ultrasound Med. Biol. 36 3 2010 419 429