Xanthine oxidase inhibition attenuates skeletal muscle signaling following acute exercise but does not impair mitochondrial adaptations to endurance training

American Journal of Physiology - Endocrinology and Metabolism

Volumn 304, Issue 8, 2013, Pages

  Wadley, G D ^a,b   Nicolas, M A ^b   Hiam, D S ^a   McConell, G K ^b,c  

^a DEAKIN UNIVERSITY   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c VICTORIA UNIVERSITY   (Australia)

Author keywords

Allopurinol; Contraction; MAPK; PGC 1a; Reactive oxygen species

Indexed keywords

3 HYDROXYACYL COENZYME A DEHYDROGENASE; ALLOPURINOL; CITRATE SYNTHASE; CYTOCHROME C; GA BINDING PROTEIN; GLUCOSE TRANSPORTER 4; GLUTATHIONE DISULFIDE; MESSENGER RNA; MITOCHONDRIAL PROTEIN; MITOCHONDRIAL TRANSCRIPTION FACTOR A; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; URIC ACID; XANTHINE OXIDASE; XANTHINE OXIDASE INHIBITOR;

ADAPTATION; ANIMAL EXPERIMENT; ARTICLE; ATTENUATION; BLOOD SAMPLING; CONTROLLED STUDY; DRUG INHIBITION; ENDURANCE TRAINING; ENZYME ACTIVITY; MALE; MITOCHONDRION; MUSCLE CONTRACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; TREADMILL EXERCISE; URIC ACID BLOOD LEVEL;

ADAPTATION, PHYSIOLOGICAL; ALLOPURINOL; ANIMALS; ENZYME INHIBITORS; GLUCOSE TRANSPORTER TYPE 4; MALE; MITOCHONDRIA; MITOGEN-ACTIVATED PROTEIN KINASES; MUSCLE CONTRACTION; MUSCLE, SKELETAL; PHENOLS; PHYSICAL ENDURANCE; PHYSICAL EXERTION; PLANT EXTRACTS; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; RNA, MESSENGER; RNA-BINDING PROTEINS; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; URIC ACID; XANTHINE; XANTHINE OXIDASE;

EID: 84878522331     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00568.2012     Document Type: Article

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