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Volumn 98, Issue 6, 2013, Pages 2604-2612

Two weeks of reduced activity decreases leg lean mass and induces "anabolic resistance" of myofibrillar protein synthesis in healthy elderly

Author keywords

[No Author keywords available]

Indexed keywords

C REACTIVE PROTEIN; INSULIN; MUSCLE PROTEIN; PHENYLALANINE DERIVATIVE; TUMOR NECROSIS FACTOR ALPHA;

EID: 84878507725     PISSN: 0021972X     EISSN: 19457197     Source Type: Journal    
DOI: 10.1210/jc.2013-1502     Document Type: Article
Times cited : (308)

References (39)
  • 1
    • 0030968884 scopus 로고    scopus 로고
    • Sarcopenia: Origins and clinical relevance
    • Rosenberg IH. Sarcopenia: origins and clinical relevance. J Nutr. 1997;127:990S-991S. (Pubitemid 27209486)
    • (1997) Journal of Nutrition , vol.127 , Issue.5 SUPPL.
    • Rosenberg, I.H.1
  • 5
    • 0034485454 scopus 로고    scopus 로고
    • The response of muscle protein anabolism to combined hyperaminoacidemia and glucose-induced hyperinsulinemia is impaired in the elderly
    • DOI 10.1210/jc.85.12.4481
    • Volpi E, Mittendorfer B, Rasmussen BB, Wolfe RR. The response of muscle protein anabolism to combined hyperaminoacidemia and glucose-induced hyperinsulinemia is impaired in the elderly. J Clin Endocrinol Metab. 2000;85:4481-4490. (Pubitemid 32157622)
    • (2000) Journal of Clinical Endocrinology and Metabolism , vol.85 , Issue.12 , pp. 4481-4490
    • Volpi, E.1    Mittendorfer, B.2    Rasmussen, B.B.3    Wolfe, R.R.4
  • 7
    • 34249678700 scopus 로고    scopus 로고
    • Aerobic exercise overcomes the age-related insulin resistance of muscle protein metabolism by improving endothelial function and Akt/mammalian target of rapamycin signaling
    • DOI 10.2337/db06-1566
    • Fujita S, Rasmussen BB, Cadenas JG, et al. Aerobic exercise overcomes the age-related insulin resistance of muscle protein metabolism by improving endothelial function and Akt/mammalian target of rapamycin signaling. Diabetes. 2007;56:1615-1622. (Pubitemid 46842620)
    • (2007) Diabetes , vol.56 , Issue.6 , pp. 1615-1622
    • Fujita, S.1    Rasmussen, B.B.2    Cadenas, J.G.3    Drummond, M.J.4    Glynn, E.L.5    Sattler, F.R.6    Volpi, E.7
  • 8
    • 84870043638 scopus 로고    scopus 로고
    • Resistance exercise enhances myofibrillar protein synthesis with graded intakes of whey protein in older men
    • Yang Y, Breen L, Burd NA, et al. Resistance exercise enhances myofibrillar protein synthesis with graded intakes of whey protein in older men. Br J Nutr. 2012;108:1780-1788.
    • (2012) Br J Nutr. , vol.108 , pp. 1780-1788
    • Yang, Y.1    Breen, L.2    Burd, N.A.3
  • 9
    • 70350118850 scopus 로고    scopus 로고
    • Effects of aging on human skeletal muscle after immobilization and retraining
    • Suetta C, Hvid LG, Justesen L, et al. Effects of aging on human skeletal muscle after immobilization and retraining. J Appl Physiol. 2009;107:1172-1180.
    • (2009) J Appl Physiol , vol.107 , pp. 1172-1180
    • Suetta, C.1    Hvid, L.G.2    Justesen, L.3
  • 10
    • 78651329227 scopus 로고    scopus 로고
    • Effects of aging on muscle mechanical function and muscle fiber morphology during short-term immobilization and subsequent retraining
    • Hvid L, Aagaard P, Justesen L, et al. Effects of aging on muscle mechanical function and muscle fiber morphology during short-term immobilization and subsequent retraining. J Appl Physiol. 2010;109:1628-1634.
    • (2010) J Appl Physiol , vol.109 , pp. 1628-1634
    • Hvid, L.1    Aagaard, P.2    Justesen, L.3
  • 12
    • 73849139203 scopus 로고    scopus 로고
    • Protecting muscle mass and function in older adults during bed rest
    • English KL, Paddon-Jones D. Protecting muscle mass and function in older adults during bed rest. Curr Opin Clin Nutr Metab Care. 2010;13:34-39.
    • (2010) Curr Opin Clin Nutr Metab Care , vol.13 , pp. 34-39
    • English, K.L.1    Paddon-Jones, D.2
  • 14
    • 84863313241 scopus 로고    scopus 로고
    • Changes in insulin sensitivity precede changes in body composition during 14 days of step reduction combined with overfeeding in healthy young men
    • Knudsen SH, Hansen LS, Pedersen M, et al. Changes in insulin sensitivity precede changes in body composition during 14 days of step reduction combined with overfeeding in healthy young men. J Appl Physiol. 2012;113:7-15.
    • (2012) J Appl Physiol , vol.113 , pp. 7-15
    • Knudsen, S.H.1    Hansen, L.S.2    Pedersen, M.3
  • 15
    • 77951959117 scopus 로고    scopus 로고
    • A 2-wk reduction of ambulatory activity attenuates peripheral insulin sensitivity
    • Krogh-Madsen R, Thyfault JP, Broholm C, et al. A 2-wk reduction of ambulatory activity attenuates peripheral insulin sensitivity. J Appl Physiol. 2010;108:1034-1040.
    • (2010) J Appl Physiol , vol.108 , pp. 1034-1040
    • Krogh-Madsen, R.1    Thyfault, J.P.2    Broholm, C.3
  • 17
    • 80053554220 scopus 로고    scopus 로고
    • Skeletal muscle protein metabolism in the elderly: Interventions to counteract the 'anabolic resistance' of ageing
    • Breen L, Phillips SM. Skeletal muscle protein metabolism in the elderly: interventions to counteract the 'anabolic resistance' of ageing. Nutr Metab (Lond). 2011;8:68.
    • (2011) Nutr Metab (Lond) , vol.8 , pp. 68
    • Breen, L.1    Phillips, S.M.2
  • 18
    • 84859517950 scopus 로고    scopus 로고
    • Canadian Institutes of Health Research, Natural Science and Engineering Research Council, Social Sciences and Humanities Research Council of Canada. Accessed May 1, 2013
    • Canadian Institutes of Health Research, Natural Science and Engineering Research Council, Social Sciences and Humanities Research Council of Canada. Tri-council policy statement: ethical conduct for research involving humans; 2010. http://www.ethics.gc.ca/pdf/eng/tcps2/TCPS-2-FINAL-Web.pdf. Accessed May 1, 2013.
    • (2010) Tri-council Policy Statement: Ethical Conduct for Research Involving Humans
  • 19
    • 79959316895 scopus 로고    scopus 로고
    • Beneficial effects of resistance exercise on glycemic control are not further improved by protein ingestion
    • Breen L, Philp A, Shaw CS, Jeukendrup AE, Baar K, Tipton KD. Beneficial effects of resistance exercise on glycemic control are not further improved by protein ingestion. PLoS One. 2011;6:e20613.
    • (2011) PLoS One , vol.6
    • Breen, L.1    Philp, A.2    Shaw, C.S.3    Jeukendrup, A.E.4    Baar, K.5    Tipton, K.D.6
  • 20
    • 80052591726 scopus 로고    scopus 로고
    • Increased consumption of dairy foods and protein during diet- and exercise-induced weight loss promotes fat mass loss and lean mass gain in overweight and obese premenopausal women
    • Josse AR, Atkinson SA, Tarnopolsky MA, Phillips SM. Increased consumption of dairy foods and protein during diet- and exercise-induced weight loss promotes fat mass loss and lean mass gain in overweight and obese premenopausal women. J Nutr. 2011;141:1626-1634.
    • (2011) J Nutr , vol.141 , pp. 1626-1634
    • Josse, A.R.1    Atkinson, S.A.2    Tarnopolsky, M.A.3    Phillips, S.M.4
  • 21
    • 0033775478 scopus 로고    scopus 로고
    • Lower limb skeletal muscle mass: Development of dual-energy x-ray absorptiometry prediction model
    • Shih R, Wang Z, Heo M, Wang W, Heymsfield SB. Lower limb skeletal muscle mass: development of dual-energy x-ray absorptiometry prediction model. J Appl Physiol. 2000;89:1380-1386.
    • (2000) J Appl Physiol , vol.89 , pp. 1380-1386
    • Shih, R.1    Wang, Z.2    Heo, M.3    Wang, W.4    Heymsfield, S.B.5
  • 23
  • 24
    • 0016723939 scopus 로고
    • Percutaneous needle biopsy of skeletal muscle in physiological and clinical research
    • Bergstrom J. Percutaneous needle biopsy of skeletal muscle in physiological and clinical research. Scand J Clin Lab Invest. 1975;35:609-616.
    • (1975) Scand J Clin Lab Invest , vol.35 , pp. 609-616
    • Bergstrom, J.1
  • 25
    • 79952324514 scopus 로고    scopus 로고
    • Validation of a single biopsy approach and bolus protein feeding to determine myofibrillar protein synthesis in stable isotope tracer studies in humans
    • Burd NA, West DW, Rerecich T, Prior T, Baker SK, Phillips SM. Validation of a single biopsy approach and bolus protein feeding to determine myofibrillar protein synthesis in stable isotope tracer studies in humans. Nutr Metab (Lond). 2011;8:15.
    • (2011) Nutr Metab (Lond) , vol.8 , pp. 15
    • Burd, N.A.1    West, D.W.2    Rerecich, T.3    Prior, T.4    Baker, S.K.5    Phillips, S.M.6
  • 26
    • 58149389265 scopus 로고    scopus 로고
    • Ingested protein dose response of muscle and albumin protein synthesis after resistance exercise in young men
    • Moore DR, Robinson MJ, Fry JL, et al. Ingested protein dose response of muscle and albumin protein synthesis after resistance exercise in young men. Am J Clin Nutr. 2009;89:161-168.
    • (2009) Am J Clin Nutr , vol.89 , pp. 161-168
    • Moore, D.R.1    Robinson, M.J.2    Fry, J.L.3
  • 27
    • 57649232182 scopus 로고    scopus 로고
    • Immobilization induces anabolic resistance inhumanmyofibrillar protein synthesis with low and high dose amino acid infusion
    • Glover EI, Phillips SM, Oates BR, et al. Immobilization induces anabolic resistance inhumanmyofibrillar protein synthesis with low and high dose amino acid infusion. J Physiol. 2008;586:6049-6061.
    • (2008) J Physiol , vol.586 , pp. 6049-6061
    • Glover, E.I.1    Phillips, S.M.2    Oates, B.R.3
  • 28
    • 67349226375 scopus 로고    scopus 로고
    • Changes in inflammatory biomarkers across weight classes in a representative US population: A link between obesity and inflammation
    • Nguyen XM, Lane J, Smith BR, Nguyen NT. Changes in inflammatory biomarkers across weight classes in a representative US population: a link between obesity and inflammation. J Gastrointest Surg. 2009;13:1205-1212.
    • (2009) J Gastrointest Surg , vol.13 , pp. 1205-1212
    • Nguyen, X.M.1    Lane, J.2    Smith, B.R.3    Nguyen, N.T.4
  • 29
    • 84861707373 scopus 로고    scopus 로고
    • Supplementation of a suboptimal protein dose with leucine or essential amino acids: Effects on myofibrillar protein synthesis at rest and following resistance exercise in men
    • Churchward-Venne TA, Burd NA, Mitchell CJ, et al. Supplementation of a suboptimal protein dose with leucine or essential amino acids: effects on myofibrillar protein synthesis at rest and following resistance exercise in men. J Physiol. 2012;590:2751-2765.
    • (2012) J Physiol , vol.590 , pp. 2751-2765
    • Churchward-Venne, T.A.1    Burd, N.A.2    Mitchell, C.J.3
  • 30
    • 0032821965 scopus 로고    scopus 로고
    • Insulin sensitivity indices obtained from oral glucose tolerance testing: Comparison with the euglycemic insulin clamp
    • DOI 10.2337/diacare.22.9.1462
    • Matsuda M, DeFronzo RA. Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp. Diabetes Care. 1999;22:1462-1470. (Pubitemid 29418240)
    • (1999) Diabetes Care , vol.22 , Issue.9 , pp. 1462-1470
    • Matsuda, M.1    DeFronzo, R.A.2
  • 31
    • 0021813187 scopus 로고
    • Homeostasis model assessment: Insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man
    • DOI 10.1007/BF00280883
    • Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia. 1985;28:412-419. (Pubitemid 15018832)
    • (1985) Diabetologia , vol.28 , Issue.7 , pp. 412-419
    • Matthews, D.R.1    Hosker, J.P.2    Rudenski, A.S.3
  • 33
    • 75949099307 scopus 로고    scopus 로고
    • EAA supplementation to increase nitrogen intake improves muscle function during bed rest in the elderly
    • Ferrando AA, Paddon-Jones D, Hays NP, et al. EAA supplementation to increase nitrogen intake improves muscle function during bed rest in the elderly. Clin Nutr. 2010;29:18-23.
    • (2010) Clin Nutr , vol.29 , pp. 18-23
    • Ferrando, A.A.1    Paddon-Jones, D.2    Hays, N.P.3
  • 35
    • 78149304854 scopus 로고    scopus 로고
    • Muscle full effect after oral protein: Time-dependent concordance and discordance between human muscle protein synthesis and mTORC1 signaling
    • Atherton PJ, Etheridge T, Watt PW, et al. Muscle full effect after oral protein: time-dependent concordance and discordance between human muscle protein synthesis and mTORC1 signaling. Am J Clin Nutr. 2010;92:1080-1088.
    • (2010) Am J Clin Nutr , vol.92 , pp. 1080-1088
    • Atherton, P.J.1    Etheridge, T.2    Watt, P.W.3
  • 36
    • 53149125147 scopus 로고    scopus 로고
    • Disassociation between the effects of amino acids and insulin on signaling, ubiquitin ligases, and protein turnover in human muscle
    • Greenhaff PL, Karagounis LG, Peirce N, et al. Disassociation between the effects of amino acids and insulin on signaling, ubiquitin ligases, and protein turnover in human muscle. Am J Physiol Endocrinol Metab. 2008;295:E595-E604.
    • (2008) Am J Physiol Endocrinol Metab , vol.295
    • Greenhaff, P.L.1    Karagounis, L.G.2    Peirce, N.3
  • 37
    • 77955347040 scopus 로고    scopus 로고
    • Insulin stimulates human skeletal muscle protein synthesis via an indirect mechanism involving endothelial-dependent vasodilation and mammalian target of rapamycin complex 1 signaling
    • Timmerman KL, Lee JL, Dreyer HC, et al. Insulin stimulates human skeletal muscle protein synthesis via an indirect mechanism involving endothelial-dependent vasodilation and mammalian target of rapamycin complex 1 signaling. J Clin Endocrinol Metab. 2010;95:3848-3857.
    • (2010) J Clin Endocrinol Metab , vol.95 , pp. 3848-3857
    • Timmerman, K.L.1    Lee, J.L.2    Dreyer, H.C.3
  • 38
    • 78049318517 scopus 로고    scopus 로고
    • Pharmacological vasodilation improves insulin-stimulated muscle protein anabolism but not glucose utilization in older adults
    • Timmerman KL, Lee JL, Fujita S, et al. Pharmacological vasodilation improves insulin-stimulated muscle protein anabolism but not glucose utilization in older adults. Diabetes. 2010;59:2764-2771.
    • (2010) Diabetes , vol.59 , pp. 2764-2771
    • Timmerman, K.L.1    Lee, J.L.2    Fujita, S.3
  • 39
    • 68549134981 scopus 로고    scopus 로고
    • Changes in basal and insulin and amino acid response of whole body and skeletal muscle proteins in obese men
    • Guillet C, Delcourt I, Rance M, et al. Changes in basal and insulin and amino acid response of whole body and skeletal muscle proteins in obese men. J Clin Endocrinol Metab. 2009;94:3044-3050.
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 3044-3050
    • Guillet, C.1    Delcourt, I.2    Rance, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.