Overdosage of Hand2 causes limb and heart defects in the human chromosomal disorder partial trisomy distal 4q

Human Molecular Genetics

Volumn 22, Issue 12, 2013, Pages 2471-2481

  Tamura, Masaru ^a,b   Hosoya, Masaki ^a,b   Fujita, Motoi ^c   Lida, Tomoko ^c   Amano, Takanori ^a   Maeno, Akiteru ^a   Kataoka, Taro ^a,b   Otsuka, Taketo ^c   Tanaka, Shigekazu ^a   Tomizawa, Shuichi ^c   Shiroishi, Toshihiko ^a,b  

^a NATIONAL INSTITUTE OF GENETICS   (Japan)

^b GRADUATE UNIVERSITY FOR ADVANCED STUDIES   (Japan)

^c Niigata National Hospital   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHROMOSOME 4Q; CHROMOSOME 6; CHROMOSOME 8; CONGENITAL HEART MALFORMATION; CONTROLLED STUDY; DEVELOPMENTAL DISORDER; EMBRYO; GENE; GENE DOSAGE; GENE INSERTION; GENETIC CROSS; GENOME; HAND2 GENE; HUMAN; HUMAN CELL; KNOCKOUT MOUSE; LIMB DEFECT; MOUSE; NONHUMAN; PARTIAL TRISOMY 4; PHENOTYPE; PRIORITY JOURNAL; RIM4 GENE;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CHROMOSOME DISORDERS; CHROMOSOMES, HUMAN, PAIR 4; DISEASE MODELS, ANIMAL; EXTREMITIES; FEMALE; GENE DOSAGE; HEART; HEART DEFECTS, CONGENITAL; HUMANS; LIMB DEFORMITIES, CONGENITAL; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; TRISOMY;

ANIMALIA; MUS;

EID: 84878492211     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddt099     Document Type: Article

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