Gold nanoparticles disrupt zebrafish eye development and pigmentation

Toxicological Sciences

Volumn 133, Issue 2, 2013, Pages 275-288

  Kim, Ki Tae ^a,b   Zaikova, Tatiana ^b,c   Hutchison, James E ^b,c   Tanguay, Robert L ^a,b  

^a OREGON STATE UNIVERSITY   (United States)

^b Safer Nanomaterials and Nanomanufacturing Initiative   (United States)

^c UNIVERSITY OF OREGON   (United States)

Author keywords

Behavior; Eye defect; Gold nanoparticles; Neuronal toxicity; Pigmentation; Zebrafish

Indexed keywords

GOLD NANOPARTICLE; LIGAND; PAIRED BOX TRANSCRIPTION FACTOR; PROTEIN BAX; PROTEIN P53; TRANSCRIPTION FACTOR OTX2; TRANSCRIPTION FACTOR SOX10; GOLD; METAL NANOPARTICLE; P53 PROTEIN, ZEBRAFISH; ZEBRAFISH PROTEIN; TRANSCRIPTION FACTOR PAX6;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DEATH; EMBRYO; EYE; EYE DEVELOPMENT; EYE MALFORMATION; EYE PIGMENTATION; GENE EXPRESSION; GROWTH INHIBITION; IN SITU HYBRIDIZATION; NONHUMAN; PIGMENT DISORDER; PIGMENTATION; ZEBRA FISH; ANIMAL; ANIMAL BEHAVIOR; ANIMAL EMBRYO; APOPTOSIS; DOSE RESPONSE; DRUG EFFECTS; EMBRYOLOGY; GENE EXPRESSION REGULATION; GENETICS; MOTOR ACTIVITY; NERVE CELL; PATHOLOGY; PHYSIOLOGY; PIGMENT EPITHELIUM; SWIMMING; TOXICITY; BEHAVIOR; DRUG EFFECT; NEURONAL TOXICITY; PRENATAL DEVELOPMENT; ZEBRAFISH.; EYE DISEASE; PROTEIN EXPRESSION;

DANIO RERIO;

ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BEHAVIOR, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; EMBRYO, NONMAMMALIAN; EYE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GOLD; IN SITU HYBRIDIZATION; METAL NANOPARTICLES; MOTOR ACTIVITY; NEURONS; PIGMENT EPITHELIUM OF EYE; SWIMMING; TUMOR SUPPRESSOR PROTEIN P53; ZEBRAFISH; ZEBRAFISH PROTEINS;

BEHAVIOR; EYE DEFECT; GOLD NANOPARTICLES; NEURONAL TOXICITY; PIGMENTATION; ZEBRAFISH.;

EID: 84878483290     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kft081     Document Type: Article

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